GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS HUMIL6GP 3085 bp ss-mRNA PRI 16-JAN-1991
DEFINITION Human membrane glycoprotein gp130, complete cds.
ACCESSION M57230
KEYWORDS interleukin 6; interleukin 6 receptor;
interleukin 6 signal transducer; membrane glycoprotein.
SOURCE Human placenta and myeloma cell line (U266), cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3085)
AUTHORS Hibi,M., Murakami,M., Saito,M., Hirano,T., Taga,T. and Kishimoto,T.
TITLE Molecular cloning and expression of an IL-6 signal transducer,
gp130
JOURNAL Cell 63, 1149-1157 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
sig_peptide 256..321
/gene="gp130 gene"
/codon_start=256
CDS 256..3012
/gene="gp130 gene"
/codon_start=256
/product="membrane glycoprotein 130"
mat_peptide 322..3009
/gene="gp130 gene"
/codon_start=322
/product="membrane glycoprotein 130"
BASE COUNT 977 a 637 c 656 g 815 t
ORIGIN
1 gagcagccaa aaggcccgcg gagtcgcgct gggccgcccc ggcgcagctg aaccgggggc
61 cgcgcctgcc aggccgacgg gtctggccca gcctggcgcc aaggggttcg tgcgctgtgg
121 agacgcggag ggtcgaggcg gcgcggcctg agtgaaaccc aatggaaaaa gcatgacatt
181 tagaagtaga agacttagct tcaaatccct actccttcac ttactaattt tgtgatttgg
241 aaatatccgc gcaagatgtt gacgttgcag acttgggtag tgcaagcctt gtttattttc
301 ctcaccactg aatctacagg tgaacttcta gatccatgtg gttatatcag tcctgaatct
361 ccagttgtac aacttcattc taatttcact gcagtttgtg tgctaaagga aaaatgtatg
421 gattattttc atgtaaatgc taattacatt gtctggaaaa caaaccattt tactattcct
481 aaggagcaat atactatcat aaacagaaca gcatccagtg tcacctttac agatatagct
541 tcattaaata ttcagctcac ttgcaacatt cttacattcg gacagcttga acagaatgtt
601 tatggaatca caataatttc aggcttgcct ccagaaaaac ctaaaaattt gagttgcatt
661 gtgaacgagg ggaagaaaat gaggtgtgag tgggatggtg gaagggaaac acacttggag
721 acaaacttca ctttaaaatc tgaatgggca acacacaagt ttgctgattg caaagcaaaa
781 cgtgacaccc ccacctcatg cactgttgat tattctactg tgtattttgt caacattgaa
841 gtctgggtag aagcagagaa tgcccttggg aaggttacat cagatcatat caattttgat
901 cctgtatata aagtgaagcc caatccgcca cataatttat cagtgatcaa ctcagaggaa
961 ctgtctagta tcttaaaatt gacatggacc aacccaagta ttaagagtgt tataatacta
1021 aaatataaca ttcaatatag gaccaaagat gcctcaactt ggagccagat tcctcctgaa
1081 gacacagcat ccacccgatc ttcattcact gtccaagacc ttaaaccttt tacagaatat
1141 gtgtttagga ttcgctgtat gaaggaagat ggtaagggat actggagtga ctggagtgaa
1201 gaagcaagtg ggatcaccta tgaagataga ccatctaaag caccaagttt ctggtataaa
1261 atagatccat cccatactca aggctacaga actgtacaac tcgtgtggaa gacattgcct
1321 ccttttgaag ccaatggaaa aatcttggat tatgaagtga ctctcacaag atggaaatca
1381 catttacaaa attacacagt taatgccaca aaactgacag taaatctcac aaatgatcgc
1441 tatctagcaa ccctaacagt aagaaatctt gttggcaaat cagatgcagc tgttttaact
1501 atccctgcct gtgactttca agctactcac cctgtaatgg atcttaaagc attccccaaa
1561 gataacatgc tttgggtgga atggactact ccaagggaat ctgtaaagaa atatatactt
1621 gagtggtgtg tgttatcaga taaagcaccc tgtatcacag actggcaaca agaagatggt
1681 accgtgcatc gcacctattt aagagggaac ttagcagaga gcaaatgcta tttgataaca
1741 gttactccag tatatgctga tggaccagga agccctgaat ccataaaggc ataccttaaa
1801 caagctccac cttccaaagg acctactgtt cggacaaaaa aagtagggaa aaacgaagct
1861 gtcttagagt gggaccaact tcctgttgat gttcagaatg gatttatcag aaattatact
1921 atattttata gaaccatcat tggaaatgaa actgctgtga atgtggattc ttcccacaca
1981 gaatatacat tgtcctcttt gactagtgac acattgtaca tggtacgaat ggcagcatac
2041 acagatgaag gtgggaagga tggtccagaa ttcactttta ctaccccaaa gtttgctcaa
2101 ggagaaattg aagccatagt cgtgcctgtt tgcttagcat tcctattgac aactcttctg
2161 ggagtgctgt tctgctttaa taagcgagac ctaattaaaa aacacatctg gcctaatgtt
2221 ccagatcctt caaagagtca tattgcccag tggtcacctc acactcctcc aaggcacaat
2281 tttaattcaa aagatcaaat gtattcagat ggcaatttca ctgatgtaag tgttgtggaa
2341 atagaagcaa atgacaaaaa gccttttcca gaagatctga aatcattgga cctgttcaaa
2401 aaggaaaaaa ttaatactga aggacacagc agtggtattg gggggtcttc atgcatgtca
2461 tcttctaggc caagcatttc tagcagtgat gaaaatgaat cttcacaaaa cacttcgagc
2521 actgtccagt attctaccgt ggtacacagt ggctacagac accaagttcc gtcagtccaa
2581 gtcttctcaa gatccgagtc tacccagccc ttgttagatt cagaggagcg gccagaagat
2641 ctacaattag tagatcatgt agatggcggt gatggtattt tgcccaggca acagtacttc
2701 aaacagaact gcagtcagca tgaatccagt ccagatattt cacattttga aaggtcaaag
2761 caagtttcat cagtcaatga ggaagatttt gttagactta aacagcagat ttcagatcat
2821 atttcacaat cctgtggatc tgggcaaatg aaaatgtttc aggaagtttc tgcagcagat
2881 gcttttggtc caggtactga gggacaagta gaaagatttg aaacagttgg catggaggct
2941 gcgactgatg aaggcatgcc taaaagttac ttaccacaga ctgtacggca aggcggctac
3001 atgcctcagt gaaggactag tagttcctgc tacaacttca gcagtaccta taaagtaaag
3061 ctaaaatgat tttatctgtg aattc
//