GenBank-Updates@genbank.bio.net (01/19/91)
LOCUS HUMCYPBX1 1809 bp ds-DNA PRI 19-JAN-1991
DEFINITION Human steroid 11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exons
1 and 2.
ACCESSION M32864 J05140
KEYWORDS steroid 11-beta-hydroxylase-like-enzyme.
SEGMENT 1 of 3
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1809)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE ;
JOURNAL Unpublished (1989) Cornell Univ., Ithaca, N.Y. 10021
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 1809)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE Characterization of two genes encoding human steroid 11-beta-
hydroxylase (P-450-11-beta)
JOURNAL J. Biol. Chem. 264, 20961-20967 (1989)
STANDARD full staff_entry
COMMENT
[J. Biol. Chem. 264, 20961-20967 (1989)] with intronic gaps.
Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
20961-20967 (1989)] kindly submitted
by P.C.White, 15-NOV-1989.
FEATURES Location/Qualifiers
precursor_RNA 576..>1809
/note="CYP11B2 mRNA and exons"
exon 583..821
/note="11-beta-hydroxylase-like-enzyme, exon 1"
intron 822..1208
/note="CYP11B2 intron A"
exon 1209..1364
/note="11-beta-hydroxylase-like-enzyme, exon 2"
intron 1365..>1809
/note="CYP11B2 intron B"
BASE COUNT 391 a 487 c 583 g 348 t
ORIGIN
1 tacatgtgtt caaaacccac agcatgttga ccaccaggag gagaccccat gtgactccag
61 ggcccctggt tgataacaac gtatcgagat tcctcacatg gaaccagtgc gcttctgtgg
121 tggagggtgt acctgtgtca gggcaggggg tacgtggaca ttttctgcag tttttgatca
181 attttgcaat gaactaatct ctggtataaa aataaagtct attaaaagaa tccaaggggc
241 cctctcatct cacgataaga taaagtcccc atccattttg ctcctctcag ccctggagaa
301 aggagaggcc aggtcccacc accttccacc agcatggacc cccagtccag accccacgcc
361 ttttctcagc atcctcagac cagcaggact tgcagcaatg gggaattagg caccagactt
421 ctccttcatc tacctttggc tgggggcctc cagccttgac cttcgctctg agagtctcag
481 gcaggtccag agccagttct cccatgacgt gatatgtttc cagagcaggt tcctgggtga
541 gataaaagga tttgggctga acagggtgga gggagcattg gaatggcact cagggcaaag
601 gcagaggtgt gcgtggcagc gccctggctg tgcctgcaaa gggcacgggc actgggcact
661 agagccgctc gggcccctag gacggtgctg ccgtttgaag ccatgcccca gcatccaggc
721 aacaggtggc tgaggctgct gcagatgtgg agggagcagg gttatgagca cctgcacctg
781 gagatgcacc agaccttcca ggagctgggg cccattttca ggtaaagccc tccctggccc
841 tcgctgggaa cacccagatc cctccccctg ctgcccagga cactgccagg cactcagcac
901 tgccattccc agcaggtccc ggcactctgc atcctttgga ggatggggaa ggagtgcagc
961 acatgctggt ctgtggtgct gccagggcag gggatagtgc agagaaaacc ccagctcact
1021 gcagagaggg caggactcag aagcactaaa gttgaaaggt tccagggagc cagcaggagg
1081 gctttagctg tgaagccgct aatccaggag cagggagggt ggacaggaga cactttggat
1141 tgggactgca gggtggggcc acgagggaca tgaccccgtc cagcagggcc tcctgcttgg
1201 ccccacaggt acaacttggg aggaccacgc atggtgtgtg tgatgctgcc ggaggatgtg
1261 gagaagctgc aacaggtgga cagcctgcat ccctgcagga tgatcctgga gccctgggtg
1321 gccatcagac aacatcgtgg gcacaaatgt ggcgtgttct tgttgtaagc ggcgagttgg
1381 gagctgagag ctgggagcag ggtgggcagc ctgggtgtag gggggaggcg agagaggtag
1441 gacccaaaag cacatctgcc ctgggcccct gtggtgggca gtgagggtga gcacccggcc
1501 cagaggacgg ccatcctgtg gggtcgcgtc tgcactgtgg gttggggaag cagggcggtg
1561 gtggagaaat gggcaggggc acctctgcag agaagacgca gagcaatgag cccttctgtg
1621 tagtgagaac ccgctctgca ccaacctcgg cggctgcttt ctcttgcggt ctggggactc
1681 tccttcccat aggtcagaaa actgaggccc tgagaagggg acttccactg gcccaggtca
1741 caggctgagt actgagcctg gtgttcgccg gggccacagc ctccctcagg gcgctcaggg
1801 tccctgcag
//GenBank-Updates@genbank.bio.net (01/19/91)
LOCUS HUMCYPBX2 3088 bp ds-DNA PRI 19-JAN-1991
DEFINITION Human steroid 11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exons
3 - 8.
ACCESSION M32880 J05140
KEYWORDS steroid 11-beta-hydroxylase-like-enzyme.
SEGMENT 2 of 3
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3088)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE ;
JOURNAL Unpublished (1989) Cornell Univ., Ithaca, N.Y. 10021
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 3088)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE Characterization of two genes encoding human steroid 11-beta-
hydroxylase (P-450-11-beta)
JOURNAL J. Biol. Chem. 264, 20961-20967 (1989)
STANDARD full staff_entry
COMMENT
[J. Biol. Chem. 264, 20961-20967 (1989)] with intronic gaps.
Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
20961-20967 (1989)] kindly submitted
by P.C.White, 15-NOV-1989.
FEATURES Location/Qualifiers
precursor_RNA <1..>3088
/note="CYP11B2 mRNA and introns"
intron <1..360
/note="CYP11B2 intron B"
exon 361..560
/note="11-beta-hydroxylase-like-enzyme, exon 3"
intron 561..697
/note="CYP11B2 intron C"
exon 698..901
/note="11-beta-hydroxylase-like-enzyme, exon 4"
intron 902..1186
/note="CYP11B2 intron D"
exon 1187..1341
/note="11-beta-hydroxylase-like-enzyme, exon 5"
intron 1342..2150
/note="CYP11B2 intron E"
exon 2151..2317
/note="11-beta-hydroxylase-like-enzyme, exon 6"
intron 2318..2716
/note="CYP11B2 intron F"
exon 2717..2795
/note="11-beta-hydroxylase-like-enzyme, exon 7"
intron 2796..2875
/note="CYP11B2 intron G"
exon 2876..3073
/note="11-beta-hydroxylase-like-enzyme, exon 8"
intron 3074..>3088
/note="CYP11B2 intron H"
BASE COUNT 592 a 906 c 985 g 605 t
ORIGIN About 800 bp after segmennt 1; chromosome 8q22.
1 aacaggggtc acctcctttc ttggagaaaa gccctaccct gttactacag ggagggcctg
61 catgggtgag gtggtgccag acttgggtcg ccaggtccca ggaatgacct cagttaccct
121 gtcagcacct gtgggcagaa gctacagtct catccctgct tagacctgag cggcctttgc
181 ccagcacctg gaggtcgctc tgagaaaagg tctgcagctc gaacacaaac aggcagcttc
241 taccagggcc ccagtcactc ctgcaggccg attccccttg ggtacaagga ggatgggata
301 cggggtcagg gcctgtgtct tgctggggcg gcctcacaag ctctgccctg gcctctgtag
361 gaatgggcct gaatggcgct tcaaccgatt gcggctgaac ccagatgtgc tgtcgcccaa
421 ggccgtgcag aggttcctcc cgatggtgga tgcagtggcc agggactttt cccaggccct
481 gaggaagaag gtgctgcaga acgcccgggg gagcctgacc ctggacgtcc agcccagcat
541 cttccactac accatagaag gtgtgggcca tgcgggaagg tccagcccca gagaccctgg
601 agtggccagg gatggggatg gaggactgaa gggagtgtgg ggaggcagcc aggaggtccg
661 gggctgcctt gtgctcagca gtgcatcctc cccgcagcca gcaacttagc tctttttgga
721 gagcggctgg gcctggttgg ccacagcccc agttctgcca gcctgaactt cctccatgcc
781 ctggaggtca tgttcaaatc caccgtccag ctcatgttca tgcccaggag cctgtctcgc
841 tggatcagcc ccaaggtgtg gaaggagcac tttgaggcct gggactgcat cttccagtac
901 ggtgaggcca gggacccggg cagtgctatg gggaagggac accatggggg cccaatttct
961 ccctctccac cacccagtgg ggaatggagg ccacagggag gggtcgggga ttcctcacct
1021 tcctgccggg gagattggtg cgaggctggg gctgggctgg gctgatccgg agaatttggg
1081 atgagagcag ggagatttgg gtgtcggggc agtctcggca ggaggaggac actgaaggat
1141 gcttcccagc accaagatct agggctgtcc cctgctccct gtacaggtga caactgtatc
1201 cagaaaatct accaggaact ggccttcaac cgccctcaac actacacagg catcgtggca
1261 gagctcctgt tgaaggcgga actgtcacta gaagccatca aggccaactc tatggaactc
1321 actgcaggga gcgtggacac ggtcaggcca gcaaccagcc ccacccagag agggtgatgc
1381 caagccctgc ctcccagcac tgcctgccaa tgccacacgg cacccacgtt ccccatcccc
1441 aggctacagg ccccacattt ctgttgccct cagccttccc cctcctttgt taagggatga
1501 gatttgcagg ggaggggaaa tgtgagctcc ccctcacatg agactgagtt tgcagttacc
1561 tgtgtgggga tccatgctcc aggctggaag aaagttggat gaggccctgg acacacagca
1621 gctctgtccc cactggaaag ctctgggtgt acaaggagaa ggagggttga gaggcagctg
1681 gaggactcca ctgggcaccc ttcccagtgt gcccggtcac cttgggccag aaatgtacat
1741 gcatgggagg gcagggttgt ggggaaggca gcagcacggg ctccagccag tgcagagggg
1801 cctgtgggtg cacagtgggg agaactcaat ggaagcagag ggagctgggg ctccagaact
1861 cccaggatga tgctgaggtc tggccccctt ttctaaggtg gctgtgagaa cccgcctgaa
1921 gaggctgcag gggacctggg ccttggtgga gatgggggtc agctttgcgt gaagaagtca
1981 gggaatctgg cccaagtggt catcaaggtt tcagatccgg cgtcccaggg ctctgtcgtg
2041 ctcagggcat ggatgtctcc acccctcaga gggaggttgt cctggctggg gtgtcccggg
2101 ggctgagtcc tcctgtgcaa ggtcagaccc tgcagacatg gcttctgtag acagcgtttc
2161 cgttgctgat gacgctcttt gagctggctc ggaaccccga cgtgcagcag atcctgcgca
2221 aggagagcct ggccgccgca gccagcatca gtgaacatcc ccagaaggca accaccgagc
2281 tgcccttgct gcgggcggcc ctcaaggaga ccttgaggtg ggtgctggat gaggcctccc
2341 tgtggccctg gccccctgct ggagagcagc ccccactggg tggtggcaga cagaatctgg
2401 ggctgataaa cagcgtcacc cagcagccca ttcccctgca cctgctcttc ctccccctca
2461 aggtctggga gctcttcttc ctctgaatcc ctcttcaaca ccctggggat taacgtgggg
2521 catgtccttc tgcgcttggg gcttctcaag ttaggggagg tttggctggg ctcagcaggt
2581 gcaaggaagc acttcgtcac gacctgggct tcccatgggc cagggagctg tgcggggtct
2641 tcggtaggaa gggtgcagag agcacaggga gccccatcca gctgaggacc ctttctgtgg
2701 atgcccccac ctccaggctc taccctgtgg gtctgttttt ggagcgagtg gtgagctcag
2761 acttggtgct tcagaactac cacatcccag ctggggtgag tgagccccca cacccctcga
2821 gctgagaacc tccctcccca gtcattccct gatccctgct ctgcaccgtc cgcagacatt
2881 ggtacaggtt ttcctctact cgctgggtcg caatgccgcc ttgttcccga ggcctgagcg
2941 gtataatccc cagcgctggc tagacatcag gggctccggc aggaacttgc accacgtgcc
3001 ctttggcttt ggcatgcgcc agtgcctcgg gcggcgcctg gcagaggcag agatgctgct
3061 gctgctgcac cacgtaagca ggcctggg
//GenBank-Updates@genbank.bio.net (01/19/91)
LOCUS HUMCYPBX3 1101 bp ds-DNA PRI 19-JAN-1991
DEFINITION Human steroid 11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon
9.
ACCESSION M32881 J05140
KEYWORDS steroid 11-beta-hydroxylase-like-enzyme.
SEGMENT 3 of 3
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1101)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE ;
JOURNAL Unpublished (1989) Cornell Univ., Ithaca, N.Y. 10021
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 1101)
AUTHORS Mornet,E., Dupont,J., Vitek,A. and White,P.C.
TITLE Characterization of two genes encoding human steroid 11-beta-
hydroxylase (P-450-11-beta)
JOURNAL J. Biol. Chem. 264, 20961-20967 (1989)
STANDARD full staff_entry
COMMENT
[J. Biol. Chem. 264, 20961-20967 (1989)] with intronic gaps.
Draft entry and computer-readable sequence for [J. Biol. Chem. 264,
20961-20967 (1989)] kindly submitted
by P.C.White, 15-NOV-1989.
FEATURES Location/Qualifiers
precursor_RNA <1..>1101
/note="CYP11B2 mRNA and introns"
intron <1..100
/note="CYP11B2 intron H"
CDS join(M32864:583..821,
M32864:1209..1364,M32880:361..560,M32880:698..901,
M32880:1187..1341,M32880:2151..2317,
M32880:2717..2795,M32880:2876..3073,101..214)
/note="11-beta-hydroxylase-like-enzyme"
exon 101..214
/note="11-beta-hydroxylase-like-enzyme, exon 9"
BASE COUNT 222 a 345 c 282 g 252 t
ORIGIN About 500 bp after segment 2; chromosome 8q22.
1 ccccttcagc ataattgttg cacctgggac gatgggagga agctgcccca ggtccatggg
61 ctactgacca ggcctgatgg aaacccagcc tctgtcctag gtgctgaagc gcttcctggt
121 ggagacacta actcaagagg acataaagat ggtctacagc ttcatattga ggcctggcac
181 gtcccccctc ctcactttca gagcgattaa ctagtcttgc atctgcaccc agggtcccag
241 cctggccacc agcttccctc tgcctgaccc caggccacct gtcttctctc ccacgtgcac
301 agcttcctga gtcacccctc tgtccagcca gctcctgcac aaatggaact ccccagggcc
361 tccaggactg gggcttgcca ggcttgtcaa atagcaaggc cagcgcacag ctggagcgat
421 cttgctgcag gcctgccttg tccccagccc cacctggccc cttctccagc aagcagtgcc
481 ctctggacac ttgactctac tcctcccagc gctggctcca ggctcctcat gaggccatgc
541 aagggtgctg tgattttgtc ccttgccttc ctgcctagtc tcacatgtcc ctgtccctct
601 cgccctggcc agggcctctg tgcagacagt gtcagagtca ttaagcggga tcccagcatc
661 tcagagtcca gtcaagttcc ctcctgcagc ctgaccccag gcagctcgag catgccctga
721 gctctctgaa agttgtcacc cagaaatacg atcctgcagg gtagactaaa aaggcccctg
781 tggtcactta tactgacaca ttttaagtga tacaactgag tctcgagggg cgtgtgttcc
841 ccagctgatc atgtcagcct catgccccag gcctcgtctt tcatggacca ggtcttgttc
901 aagcagcgag tgttgggtcc tctgcttcct gagctgtccc ctggaaaagg tcccgaggat
961 gctgtcagga gatggaagag tcatgtgggg tgggaacctg gggtgtggtt ccagaaatgt
1021 ttttggcaac aggagagaca ggattgggcc aacaaggact cagatgagtt tattgactca
1081 ttcctctgga agatacgcag c
//