GenBank-Updates@genbank.bio.net (01/19/91)
LOCUS HUMGSHPXG 1733 bp ds-DNA PRI 19-JAN-1991 DEFINITION Human glutathione peroxidase gene, complete cds. ACCESSION Y00483 KEYWORDS glutathione peroxidase. SOURCE Human leukocyte DNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 1733) AUTHORS Ishida,K. TITLE ; JOURNAL Unpublished (1987) Nippon Kayaku Co.,Ltd, Kita-ku, Tokyo 115, Japan STANDARD simple automatic REFERENCE 2 (bases 1 to 1733) AUTHORS Ishida,K., Morino,T., Takagi,K. and Sukenaga,Y. TITLE Nucleotide sequence of a human gene for glutathione peroxidase JOURNAL Nucleic Acids Res. 15, 10051-10051 (1987) STANDARD simple automatic COMMENT An in-phase 'tga' codon is located at positions 612-614 and encodes selenocysteine. FEATURES Location/Qualifiers CDS join(474..611,615..719,998..1357) /note="glutathione peroxidase" precursor_RNA 155..1566 /note="GTP mRNA and intron" exon 474..611 /note="glutathione peroxidase, exon 1 (EC 1.11.1.9). /nomgen='GPX1' /map='3q11-q12' /hgml_locus_uid='LE0062E'" exon 615..719 /note="glutathione peroxidase, exon 1" intron 720..997 /note="GTP intron" exon 998..1357 /note="glutathione peroxidase, exon 2" BASE COUNT 277 a 529 c 526 g 401 t ORIGIN 1 aacctagatc cctctgctgt cccctgcact gccggtaaca tggcacagca gagcagggtt 61 gtttgtgcac gggcagctcc tgcagctgct gccgtcgccc accagcctcc tatgccaaac 121 cccacatcct aactcaggaa cctctgagaa aaaacggagc cctcgagggg cccagccttg 181 gaagggtaac tggaccgctg ccgcctggtt gcctgggcca gaccagacat gcctgctgct 241 ccttccggct taggaggagc acgcgtcccg ctcgcgcgca ctctccagcc ttttcctggc 301 tgaggagggg ccgagcctcc ggtagggcgg gggccggatg aggcgggacc tcaggcccgg 361 aaaactgcct gtgccacgtg acccgccgcc ggccagttaa aaggaggcgc ctgctggcct 421 ccccttacag tgcttgttcg gggcgctccg ctggcttctt ggacaattgc gccatgtgtg 481 ctgctcggct agcggcggcg gcggcccagt cggtgtatgc cttctcggcg cgcccgttgg 541 ccggcgggga gcctgtgagc ctgggctccc tgcggggcaa ggtactactt atcgagaatg 601 tggcgtccct ctgaggcacc acggtccggg actacaccca gatgaacgag ctgcagcggc 661 gcctcggacc ccggggcctg gtggtgctcg gcttcccgtg caaccagttt gggcatcagg 721 tgcgccgggc ggagcgggac gggacggggg cggacgtgca gtagtggctg ggggcgccgg 781 cggtgtggtg gtgggtgcgt cggctccatg cgcggagagt ctggctactc tctcgtttcc 841 tttctgttgc tcgtagctgc tgaaattcct ctccgccctt gggattgcgc atggagggaa 901 aaatcccggt gactcataga aaatctcccc tgtttgtggt tagaacgttt ctctcctcct 961 cttgaccccg ggttctagct gcccttctct cctgtaggag aacgccaaga acgaagagat 1021 tctgaattcc ctcaagtacg tccggcctgg tggtgggttc gagcccaact tcatgctctt 1081 cgagaagtgc gaggtgaacg gtgcgggggc gcaccctctc ttcgccttcc tgcgggaggc 1141 cctgccagct cccagcgacg acgccaccgc gcttatgacc gaccccaagc tcatcacctg 1201 gtctccggtg tgtcgcaacg atgttgcctg gaactttgag aagttcctgg tgggccctga 1261 cggtgtgccc ctacgcaggt acagccgccg cttccagacc attgacatcg agcctgacat 1321 cgaagccctg ctgtctcaag ggcccagctg tgcctagggc gcccctccta ccccggctgc 1381 ttggcagttg cagtgctgct gtctcggggg ggttttcatc tatgagggtg tttcctctaa 1441 acctacgagg gaggaacacc ttgatcttac agaaaatacc acctcgagat gggtgctggt 1501 cctgttgatc ccagtctctg ccagaccaag gctagtttcc ccactaataa agtgccgggt 1561 gtcagcagac tgtgtgtatg tcctgtgtca ttgtcatttg ggaattcttt ttcttttctt 1621 tttttttttt tttttttgag acggagtttt ttgctctatt gcccaggctt gagtgcagtg 1681 gcgcaatcta ggctcactgc aagctccgcc tcccgggttc agcatttctg cta //