GenBank-Updates@genbank.bio.net (01/23/91)
LOCUS HUMRAF1PR 1194 bp ds-DNA UNA 23-JAN-1991
DEFINITION Human raf-1 oncogene promoter region.
ACCESSION M38134
KEYWORDS promoter region; raf-1 oncogene.
SOURCE Human liver DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1194)
AUTHORS Beck,T.W., Brennscheidt,U., Sithanandam,G., Cleveland,J. and
Rapp,U.R.
TITLE Molecular organization of the human Raf-1 promoter region
JOURNAL Mol. Cell. Biol. 10, 3325-3333 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
misc_feature 110..117
/type="octamer motif"
/gene="raf-1"
protein_bind 413..422
/bound_moiety="Sp1 protein"
/gene="raf-1"
protein_bind 675..684
/bound_moiety="Sp1 protein"
/gene="raf-1"
protein_bind 686..695
/bound_moiety="Sp1 protein"
/gene="raf-1"
mRNA 844..>1194
/gene="raf-1"
mRNA 845..>1194
/gene="raf-1"
mRNA 846..>1194
/gene="raf-1"
mRNA 870..>1194
/gene="raf-1"
mRNA 871..>1194
/gene="raf-1"
protein_bind 1027..1036
/bound_moiety="Sp1 protein"
/gene="raf-1"
RBS 1147..1152
/standard_name="Shine-Diago"
/gene="raf-1"
BASE COUNT 243 a 305 c 373 g 273 t
ORIGIN
1 aactatctag ttcattcttg gatggatgac aacccagatt ggatgtgtag cagcgttctc
61 ttaaccagtt tcctattaat cttcatttca tccccagtgt ttctccagaa tgcaaataat
121 atggcattaa atatcttcac acatagcttt ttgtgtatgt gtatacttat ttctctagaa
181 ttagtgtcta gaagtgaaac tgccgggaga aggatatata cttttaacat gtccaagttc
241 cactgtgata gcgctgcgag ggcacacaac aggtttcaat ataccttgga ccaaaccgga
301 tattatcagt ttttttaact tgttgctaat gtgatggggg aaaaatgaac tcggaattta
361 cacacaagga aaagaccgtt taaggttcag ggactgtcca catagctgtc aagtggcgga
421 gccgtgattt ggtattaaag tgcccggaga ggacgcgtca aagttggaca ctgtgccctg
481 tgtcctgagg cacgtctggt gatcgctggg ccttgcaatg ctgggcaggc aggccttcct
541 ctccccttct aggcctctgg ccactcctgg ctggccgaaa gccggttctt ctcgattacc
601 gagtgcctct cctgaaagca agtcagcgtc gcctaacctc ttcagcttcg aaatggcggc
661 caccagatcg ctaggccacg ccccgggggc gggcctgagt tcaggccaga gcgatggatg
721 cccgagccaa gttagaagtc gactgccagt agggctcgcg cagaatcgga ggccggtggc
781 gtcgcggtcg ggaggacgga gcaccgagtc gagggctcgc tcgtctgggc cgcccgagag
841 tcttaatcgc gggcgctttg gcgccatctt tagatggcgg gagtaagagg aaaacgattg
901 tgaggcggga acggctttct gctgcctttt ttgggccccg aaaagggtca gctggccggg
961 ctttggggcg cgtgcctgag gcgcggacgc gtttgctacg atgcgggggc tgctcggggc
1021 tccgtccctg ggctggggac gcgccgaatg tgaccgcctc ccgctccctc acccgccgcg
1081 gggaggagga gcgggcgaga agctgccgcc gaacgacagg acgttggggc ggcctggctc
1141 cctcaggtag gtggcaggac cgggtcgtgg atgccggggg agccggcggc gggc
//