GenBank-Updates@genbank.bio.net (01/23/91)
LOCUS HUMTCRB21 1261 bp ds-DNA PRI 23-JAN-1991
DEFINITION Human T-cell receptor beta chain gene variable region.
ACCESSION M33233
KEYWORDS T-cell receptor beta chain; variable region.
SOURCE Human sperm DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1261)
AUTHORS Wilson,R.K., Lai,E., Kim,L.D. and Hood,L.
TITLE Sequence and expression of a novel human T-cell receptor beta-chain
variable gene segment subfamily
JOURNAL Immunogenetics 32, 406-412 (1990)
STANDARD full staff_entry
COMMENT Authorin copy of sequence [Unpublished (1990) CIT, 391 S.Holliston
Ave., Pasadena,CA 91125] kindly submitted by R.K.Wilson
26-MAR-1990.
FEATURES Location/Qualifiers
CDS join(589..637,739..1031)
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
/partial
exon <589..637
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
misc_signal 504..508
/note="TATA box"
intron 638..738
/note="intron A"
exon 739..>1031
/note="T-cell receptor beta chain gene variable region"
misc_signal 1037..1043
/note="heptamer rearrangement signal"
misc_signal 1066..1074
/note="nonamer rearrangement signal"
BASE COUNT 336 a 305 c 277 g 343 t
ORIGIN
1 aagcttgata acagaaaaga gaaagctggc cattgacctt caccaaaaat gaacccttcc
61 aactctctct cagggtatta ttttacccct ttagcttaga gcatgtcagc tggttcaaca
121 tgcttctagg ataaacctgt gtcaactacc ccagctccca ctctgtctaa gctcatagca
181 atgagaaaat ggagaacctg gtaagacaga aatgcccaga gagaaggata tacagataag
241 acatagaggt tactaattgt tgtctgtatt ttgagttgcc tttgacacat tcaagtagaa
301 acatgcagca gaagatggcc ctggagatgc agtgggtgat ccaatccccc aagccctaga
361 gatgtgagta aagacacttg gatgaactta cacacagtcc atgatacgct aaagcaactt
421 ctagctctgt tttagttcat aacaactggt ttctaagaac ttaggcactt gtggagacaa
481 tgatgttact gtaggaacta ccgtataagg acaggatgtc ccacctcctc tgctcctgtt
541 cacaaggacc ctgaactggc aaagctccca tcctgccctg accctgccat gagcaccagg
601 cttctctgct ggatggccct ctgtctcctg ggggcaggtg tgtcctaaga acaccatgat
661 catcccattg gaaattccag tgatttcttc aatcatttct gtctttctgt tttcaaattc
721 tgtctttttc cccaacagaa ctctcagaag ctgaagttgc ccagtccccc agatataaga
781 ttacagagaa aagccaggct gtggcttttt ggtgtgatcc tatttctggc catgctaccc
841 tttactggta ccggcagatc ctgggacagg gcccggagct tctggttcaa tttcaggatg
901 agagtgtagt agatgattca cagttgccta aggatcgatt ttctgcagag aggctcaaag
961 gagtagactc cactctcaag atccagcctg cagagcttgg ggactcggcc atgtatctct
1021 gtgccagcag cttagccaca gcgttgcaga gactttctct cctgtgcaca aaactccagg
1081 gctctctccg ctctactcag ctcacagcag cctttcctta ttcctcatcc tctcagggaa
1141 gaagtgagtt ttcagatata gctagggttc atatagtggg aggaaatgaa ctattttctt
1201 aaaacatgag cgctatagtt gttggttgaa aacatgtctt agggatttga aacacttctg
1261 g
//GenBank-Updates@genbank.bio.net (01/23/91)
LOCUS HUMTCRB22 1669 bp ds-DNA PRI 23-JAN-1991
DEFINITION Human T-cell receptor beta chain gene variable region.
ACCESSION M33234
KEYWORDS T-cell receptor beta chain; variable region.
SOURCE Human sperm DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1669)
AUTHORS Wilson,R.K., Lai,E., Kim,L.D. and Hood,L.
TITLE Sequence and expression of a novel human T-cell receptor beta-chain
variable gene segment subfamily
JOURNAL Immunogenetics 32, 406-412 (1990)
STANDARD full staff_entry
COMMENT Authorin copy of sequence [Unpublished (1990) CIT, 391 S.Holliston
Ave., Pasadena,CA 91125] kindly submitted by R.K.Wilson
26-MAR-1990.
FEATURES Location/Qualifiers
CDS join(591..639,732..1024)
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
/partial
exon <591..639
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
misc_signal 505..509
/note="TATA box"
intron 640..731
/note="intron A"
exon 732..>1024
/note="T-cell receptor beta chain gene variable region"
misc_signal 1030..1036
/note="heptamer rearrangement signal"
misc_signal 1060..1068
/note="nonamer rearrangement signal"
BASE COUNT 493 a 356 c 346 g 474 t
ORIGIN
1 aggcttcata cataatacat aatgaagatt gagtaacagc aaaaagggaa ctagtcattg
61 gccttcagat aaaatgaaac ctcccaactt tgtgctcagg gaattattta cccctttagg
121 ttagagtatg tcagctagtt caatgcagtt ctaggataaa gctgtgtcaa ttaccctaga
181 ggactgggag catggaggac ctggtagaaa agaaataccc aaagagaagg aaaattacac
241 acaaaatcaa gaggtcacta attgatatat ctattttgag ttgcctttga gacttccacg
301 tagaaacatc tagcacagga taggcctaga gatgtagtga cagatctaat cccccaagcc
361 ctgatatgtg agtgaggacg cttggatgaa cttccagtct atgaatacat taaacaaact
421 tttagctctg ttttagttta caacaactgt tttctaagaa cttaagcatt tgtggagaca
481 atgatgtcac tgtaggaact tctctgtaag gacagcaaca tcccacttcc tctgctcctg
541 ctcacagtga ccctgatctg gcaaagcttc catcctgccc tgaccctgcc atgggtacca
601 ggctcctctg ctgggtggcc ttctgtctcc tggtggaagg tgagtcctag gaacaccatg
661 atcctcacat aatctcccag tgattattcc tagtcatttc cttctatttt aaaattcttt
721 ttcccccaca gaactcatag aagctggagt ggttcagtct cccagatata agattataga
781 gaaaaaacag cctgtggctt tttggtgcaa tcctatttct ggccacaata ccctttactg
841 gtacctgcag aacttgggac agggaacgga gcttctgatt cgatatgaga atgaggaagc
901 agtagacgat tcacagttgc ctaaggaacg attttctgaa gagaggataa aaggagtaga
961 ctccactctc aagaaccagc ctgcagagct tgggaactcg gccgtgtatc tctgtgccag
1021 cagcttagac acagtgtagc agagacactt ccctcctgtg cagaaaaccg caggactctc
1081 tcctctctac tcagctcaca gcagcctttc cttattcctc atcctcccag aaagaagtga
1141 gttttcagat atagctagat tcatatagtg gagaaatgaa ctattttctt acaacatgag
1201 cgctataatt gttgcttgaa aatgtgtctc agggatttga aacacttctt gggacaactc
1261 aagaaaccta aagtgactta tcagagattg agtcctcagg ggtagtgatg gtttatgtgg
1321 gataaaagta tgtgatcatg tttcatgtac aataaactta taaatcagat agtgattata
1381 ccaagacacg caaacagcag gctcccctta tgtagttgtc agcatgtgaa tgattgttac
1441 ccttagtgac aaccccggct gtctagtctg caaagtctca acacacagta tgtgtttggc
1501 aaatcttttt ccttctgttt tatttttggt aaagtatgct aagaatgatg ttgttaatga
1561 tagtgattat aatttcaggt atgttattca gccctttttc cagttcaaag aaatgaacac
1621 aaatggatac cccggcaacc aggtgcaaat cttagctcca gatgaattc
//GenBank-Updates@genbank.bio.net (01/23/91)
LOCUS HUMTCRB23 455 bp ds-DNA PRI 23-JAN-1991
DEFINITION Human T-cell receptor beta chain gene variable region.
ACCESSION M33235
KEYWORDS T-cell receptor beta chain; variable region.
SOURCE Human placenta DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 455)
AUTHORS Wilson,R.K., Lai,E., Kim,L.D. and Hood,L.
TITLE Sequence and expression of a novel human T-cell receptor beta-chain
variable gene segment subfamily
JOURNAL Immunogenetics 32, 406-412 (1990)
STANDARD full staff_entry
COMMENT Authorin copy of sequence [Unpublished (1990) CIT, 391 S.Holliston
Ave., Pasadena,CA 91125] kindly submitted by R.K.Wilson
26-MAR-1990.
FEATURES Location/Qualifiers
CDS join(22..70,163..>455)
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
exon 22..70
/note="T-cell receptor beta chain gene variable region
/hgml_locus_uid='LP0151Q' /map='7q35' /nomgen='TCRB'"
intron 71..162
/note="intron A"
exon 163..>455
/note="T-cell receptor beta chain gene variable region"
BASE COUNT 105 a 119 c 104 g 127 t
ORIGIN
1 ccatcctgcc ctgaccctgc catgggcacc aggctcctct gctgggcggc cctctgtctc
61 ctgggagcag gtgagtccta ggaacaccat gatcacattg gatctctctg attatttcaa
121 tcatttcctt ctattttcaa attctgtctt tttccttctc agaactcaca gaagctggag
181 ttgcccagtc tcccagatat aagattatag agaaaaggca gagtgtggct ttttggtgca
241 atcctatatc tggccatgct accctttact ggtaccagca gatcctggga cagggcccaa
301 agcttctgat tcagtttcag aataacggtg tagtggatga ttcacagttg cctaaggatc
361 gattttctgc agagaggctc aaaggagtag actccactct caagatccag cctgcaaagc
421 ttgagaactc ggccgtgtat ctctgtgcca gcagt
//