GenBank-Updates@genbank.bio.net (12/22/90)
LOCUS HUMIREBP 3355 bp ss-mRNA PRI 22-DEC-1990
DEFINITION Human iron-responsive element-binding protein mRNA, complete cds.
ACCESSION M58510 M37835
KEYWORDS RNA regulatory protein; iron-responsive element-binding protein.
SOURCE Human T cell line 4T, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3355)
AUTHORS Rouault,T.A., Tang,C.K., Kaptain,S., Burgess,W.H., Haile,D.J.,
Samaniego,F., McBride,O.W., Harford,J.B. and Klausner,R.D.
TITLE Cloning of the cDNA encoding RNA regulatory protein-the human
iron-responsive element-binding protein
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 7958-7962 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
mRNA 1..3355
/gene="IRE-BP"
/partial
/product="iron-responsive regulatory protein"
CDS 262..2634
/gene="IRE-BP"
/codon_start=262
/product="iron-responsive regulatory protein"
BASE COUNT 882 a 773 c 805 g 895 t
ORIGIN
1 cccacacact gacatgacag ggcttgggca agactcctgt tctacttatc cttttgaaat
61 acctcaccct gccactccac catgtatgat cattccagag atctttgtga ctagagttag
121 tgtcctagga aaaccagaac tcagaacttg cctccatggt tgagtaacaa gctgtacaag
181 aacatagaag tgccatttaa gcctgctcgt gtcatcctgc aggactttac gggtgtgccc
241 gctgtggttg actttgctgc aatgcgtgat gctgtgaaaa agttaggagg agatccagag
301 aaaataaacc ctgtctgccc tgctgatctt gtaatagatc attccatcca ggttgatttc
361 aacagaaggg cagacagctt acagaagaat caagacctgg aatttgaaag aaatagagag
421 cgatttgaat ttttaaagtg gggttcccag gcttttcaca acatgcggat tattccccct
481 ggctcaggaa tcatccacca ggtgaatttg gaatatttgg caagagtggt atttgatcag
541 gatggatatt attacccaga cagcctcgtg ggcacagact cgcacactac catgattgat
601 ggcttgggca ttcttggttg gggtgtcggt ggtattgaag cagaagctgt catgctgggt
661 cagccaatca gtatggtgct tcgtcaggtg attggctaca ggctgatggg gaagccccac
721 cctctggtaa catccactga catcgtgctc accattacca agcacctccg ccaggttggg
781 gtagtgggca aatttgtcga gttcttcggg cctggagtag cccagttgtc cattgctgac
841 cgagctacga ttgctaacat gtgtccagag tacggagcaa ctgctgcctt tttcccagtt
901 gatgaagtta gtatcacgta cctggtgcaa acaggtcgtg atgaagaaaa attaaagtat
961 attaaaaaat atcttcaggc tgtaggaatg tttcgagatt tcaatgaccc ttctcaagac
1021 ccagacttca cccaggttgt ggaattagat ttgaaaacag tagtgccttg ctgtagtgga
1081 cccaaaaggc ctcaggacaa agttgctgtg tccgacatga aaaaggactt tgagagctgc
1141 cttggagcca agcaaggatt taaaggattc caagttgctc ctgaacatca taatgaccat
1201 aagaccttta tctatgataa cactgaattc acccttgctc atggttctgt ggtcattgct
1261 gccattacta gctgcacaaa caccagtaat ccgtctgtga tgttaggggc aggattgtta
1321 gcaaagaaag ctgtggatgc tggcctgaac gtgatgcctt acatcaaaac tagcctgtct
1381 cctgggagtg gcgtggtcac ctactaccta caagaaagcg gagtcatgcc ttatctgtct
1441 cagcttgggt ttgacgtggt gggctatggc tgcatgacct gcattggcaa cagtgggcct
1501 ttacctgaac ctgtggtaga agccatcaca cagggagacc ttgtagctgt tggagtcatc
1561 attggaacag gaattttgaa ggctgagctt taccccaaca cccgggccaa ctatttagcc
1621 tctcccccct tagtaatagc atatgcaatt gctggaacca tcagaatcga ctttgagaaa
1681 gagccattgg gagtaaatgc aaagggacag caggtatttc tgaaagatat ctggccgact
1741 agagacgaga tccaggcagt ggagcgtcag tatgtcatcc cggggatgtt taaggaagtc
1801 tatcagaaaa tagagactgt gaatgaaagc tggaatgcct tagcaacccc atcagataag
1861 ctgtttttct ggaattccaa atctacgtat atcaaatcac caccattctt tgaaaacctg
1921 actttggatc ttcagccccc taaatctata gtggatgcct atgtgctgct aaatttggga
1981 gattcggtaa caactgacca catctcccca gctggaaata ttgcaagaaa cagtcctgct
2041 gctcgctact taactaacag aggcctaact ccacgagaat tcaactccta tggctccccc
2101 gaggtaatga cgccgtcatg gcacggggaa catttgccaa cattgcgctt gttaaacaga
2161 tttttgaaca agcaggcacc acagactatc catctgcctt ctggggaaat ccttgatgtg
2221 tttgatgctg ctgagcggta ccagcaggca ggccttcccc tgatcgttct ggctggcaaa
2281 gagtacggtg caggcagctc ccgagactgg gcagctaagg gccctttcct gctgggaatc
2341 aaagccgtcc tggccgagag ctacgagcgc attcaccgca gtaacctggt tgggatgggt
2401 gtgatcccac ttgaatatct ccctggtgag aatgcagatg ccctggggct cacagggcaa
2461 gaacgataca ctatcattat tccagaaaac ctcaaaccac aaatgaaagt ccaggtcaag
2521 ctggatactg gcaagacctt ccaggctgtc atgaggtttg acactgatgt ggagctcact
2581 tatttcctca acgggggcat cctcaactac atgatccgca agatggccaa gtaggagacg
2641 tgcacttggt cgtgcgccca gggaggaagc cgcaccacca gccagcgcag gccctggtgg
2701 agaggcctcc ctggctgcct ctgggagggg tgctgccttg tagatggagc aagtgagcac
2761 tgagggtctg gtgccaatcc tgtaggcaca aaaccagaag gttctacatt ctctattttt
2821 gttaatcatc ttctcttttt ccagaatttg gaagctagaa tggtgggaat gtcagtagtg
2881 ccagaaagag agaaccaagc ttgtctttaa agttactgat cacaggacgt tgctttttca
2941 ctgtttccta ttaatcttca gctgaacaca agcaaacctt ctcaggaggt gtctcctacc
3001 ctcttattgt tcctcttacg ctctgctcaa tgaaaccttc ctcttgaggg tcattttcct
3061 ttctgtatta attataccag tgttaagtga catagataag aactttgcac acttcaaatc
3121 agagcagtga ttctctcttc tctccccttt tccttcagag tgaatcatcc agactcctca
3181 tggataggtc gggtgttaaa gttgttttga ttatgtacct tttgatagat ccacataaaa
3241 agaaatgtga agttttcttt tactatcttt tcatttatca agcagagacc tttgttggga
3301 ggcggtttgg gagaacacat ttctaatttg aatgaaatga aatctatttt cagtg
//GenBank-Updates@genbank.bio.net (12/22/90)
LOCUS HUMIREBPA 3354 bp ss-mRNA PRI 22-DEC-1990
DEFINITION Human iron -responsive element-binding protein mRNA, complete cds.
ACCESSION M58511 M37836
KEYWORDS RNA regulatory protein; iron-responsive element-binding protein.
SOURCE Human adult T cell line YT, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3354)
AUTHORS Rouault,T.A., Tang,C.K., Kaptain,S., Burgess,W.H., Haile,D.J.,
Samaniego,F., McBride,O.W., Harford,J.B. and Klausner,R.D.
TITLE Cloning of the cDNA encoding RNA regulatory protein-the human
iron-responsive element-binding protein
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 7958-7962 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 261..2633
/gene="IRE-BP"
/codon_start=261
/product="iron-responsive element -binding protein"
BASE COUNT 882 a 773 c 804 g 895 t
ORIGIN
1 ccacacactg acatgacagg gcttgggcaa gactcctgtt ctacttatcc ttttgaaata
61 cctcaccctg ccactccacc atgtatgatc attccagaga tctttgtgac tagagttagt
121 gtcctaggaa aaccagaact cagaacttgc ctccatggtt gagtaacaag ctgtacaaga
181 acatagaagt gccatttaag cctgctcgtg tcatcctgca ggactttacg ggtgtgcccg
241 ctgtggttga ctttgctgca atgcgtgatg ctgtgaaaaa gttaggagga gatccagaga
301 aaataaaccc tgtctgccct gctgatcttg taatagatca ttccatccag gttgatttca
361 acagaagggc agacagctta cagaagaatc aagacctgga atttgaaaga aatagagagc
421 gatttgaatt tttaaagtgg ggttcccagg cttttcacaa catgcggatt attccccctg
481 gctcaggaat catccaccag gtgaatttgg aatatttggc aagagtggta tttgatcagg
541 atggatatta ttacccagac agcctcgtgg gcacagactc gcacactacc atgattgatg
601 gcttgggcat tcttggttgg ggtgtcggtg gtattgaagc agaagctgtc atgctgggtc
661 agccaatcag tatggtgctt cctcaggtga ttggctacag gctgatgggg aagccccacc
721 ctctggtaac atccactgac atcgtgctca ccattaccaa gcacctccgc caggttgggg
781 tagtgggcaa atttgtcgag ttcttcgggc ctggagtagc ccagttgtcc attgctgacc
841 gagctacgat tgctaacatg tgtccagagt acggagcaac tgctgccttt ttcccagttg
901 atgaagttag tatcacgtac ctggtgcaaa caggtcgtga tgaagaaaaa ttaaagtata
961 ttaaaaaata tcttcaggct gtaggaatgt ttcgagattt caatgaccct tctcaagacc
1021 cagacttcac ccaggttgtg gaattagatt tgaaaacagt agtgccttgc tgtagtggac
1081 ccaaaaggcc tcaggacaaa gttgctgtgt ccgacatgaa aaaggacttt gagagctgcc
1141 ttggagccaa gcaaggattt aaaggattcc aagttgctcc tgaacatcat aatgaccata
1201 agacctttat ctatgataac actgaattca cccttgctca tggttctgtg gtcattgctg
1261 ccattactag ctgcacaaac accagtaatc cgtctgtgat gttaggggca ggattgttag
1321 caaagaaagc tgtggatgct ggcctgaacg tgatgcctta catcaaaact agcctgtctc
1381 ctgggagtgg cgtggtcacc tactacctac aagaaagcgg agtcatgcct tatctgtctc
1441 agcttgggtt tgacgtggtg ggctatggct gcatgacctg cattggcaac agtgggcctt
1501 tacctgaacc tgtggtagaa gccatcacac agggagacct tgtagctgtt ggagtcatca
1561 ttggaacagg aattttgaag gctgagcttt accccaacac ccgggccaac tatttagcct
1621 ctcccccctt agtaatagca tatgcaattg ctggaaccat cagaatcgac tttgagaaag
1681 agccattggg agtaaatgca aagggacagc aggtatttct gaaagatatc tggccgacta
1741 gagacgagat ccaggcagtg gagcgtcagt atgtcatccc ggggatgttt aaggaagtct
1801 atcagaaaat agagactgtg aatgaaagct ggaatgcctt agcaacccca tcagataagc
1861 tgtttttctg gaattccaaa tctacgtata tcaaatcacc accattcttt gaaaacctga
1921 ctttggatct tcagccccct aaatctatag tggatgccta tgtgctgcta aatttgggag
1981 attcggtaac aactgaccac atctccccag ctggaaatat tgcaagaaac agtcctgctg
2041 ctcgctactt aactaacaga ggcctaactc cacgagaatt caactcctat ggctcccccg
2101 aggtaatgac gccgtcatgg cacggggaac atttgccaac attgcgcttg ttaaacagat
2161 ttttgaacaa gcaggcacca cagactatcc atctgccttc tggggaaatc cttgatgtgt
2221 ttgatgctgc tgagcggtac cagcaggcag gccttcccct gatcgttctg gctggcaaag
2281 agtacggtgc aggcagctcc cgagactggg cagctaaggg ccctttcctg ctgggaatca
2341 aagccgtcct ggccgagagc tacgagcgca ttcaccgcag taacctggtt gggatgggtg
2401 tgatcccact tgaatatctc cctggtgaga atgcagatgc cctggggctc acagggcaag
2461 aacgatacac tatcattatt ccagaaaacc tcaaaccaca aatgaaagtc caggtcaagc
2521 tggatactgg caagaccttc caggctgtca tgaggtttga cactgatgtg gagctcactt
2581 atttcctcaa cgggggcatc ctcaactaca tgatccgcaa gatggccaag taggagacgt
2641 gcacttggtc gtgcgcccag ggaggaagcc gcaccaccag ccagcgcagg ccctggtgga
2701 gaggcctccc tggctgcctc tgggaggggt gctgccttgt agatggagca agtgagcact
2761 gagggtctgg tgccaatcct gtaggcacaa aaccagaagg ttctacattc tctatttttg
2821 ttaatcatct tctctttttc cagaatttgg aagctagaat ggtgggaatg tcagtagtgc
2881 cagaaagaga gaaccaagct tgtctttaaa gttactgatc acaggacgtt gctttttcac
2941 tgtttcctat taatcttcag ctgaacacaa gcaaaccttc tcaggaggtg tctcctaccc
3001 tcttattgtt cctcttacgc tctgctcaat gaaaccttcc tcttgagggt cattttcctt
3061 tctgtattaa ttataccagt gttaagtgac atagataaga actttgcaca cttcaaatca
3121 gagcagtgat tctctcttct ctcccctttt ccttcagagt gaatcatcca gactcctcat
3181 ggataggtcg ggtgttaaag ttgttttgat tatgtacctt ttgatagatc cacataaaaa
3241 gaaatgtgaa gttttctttt actatctttt catttatcaa gcagagacct ttgttgggag
3301 gcggtttggg agaacacatt tctaatttga atgaaatgaa atctattttc agtg
//GenBank-Updates@genbank.bio.net (01/24/91)
LOCUS HUMIREBPA 3402 bp ss-mRNA PRI 24-JAN-1991
DEFINITION Human iron -responsive element-binding protein mRNA, complete cds.
ACCESSION M58511 M37836
KEYWORDS RNA regulatory protein; iron-responsive element-binding protein.
SOURCE Human adult T cell line YT, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3402)
AUTHORS Rouault,T.A., Tang,C.K., Kaptain,S., Burgess,W.H., Haile,D.J.,
Samaniego,F., McBride,O.W., Harford,J.B. and Klausner,R.D.
TITLE Cloning of the cDNA encoding RNA regulatory protein-the human
iron-responsive element-binding protein
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 7958-7962 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 364..2844
/note="The start site at 364 is putative."
/gene="IRE-BP"
/codon_start=364
/product="iron-responsive element -binding protein"
BASE COUNT 1037 a 626 c 739 g 1000 t
ORIGIN
1 aggcctcccc cttcttcccc cgctggcccc ctccccggag ggataatatg gtctccggcg
61 atggacgccc caaaagcagg atacgccttt gagtacctta ttgaaacatt aaatgacagt
121 tcacataaga agttcttcga tgtatctaaa cttggcacca agtatgatgt tctgccttac
181 tcaatacggg tcttgttgga agctgctgta cgaaattgtg atggcttttt aatgaagaag
241 gaagatgtta tgaacatttt agactggaaa accaaacaaa gcaatgttga agtgcccttt
301 ttccctgccc gtgttcttct tcctcatttt actggaatac cagcaatggt ggattttgct
361 gctatgaggg aggcagtgaa aactcttgga ggtgatcctg agaaagtcca tcctgcttgt
421 ccgacagatc ttacagttga ccattcttta caaattgact tcagtaaatg tgcaatacag
481 aatgcaccaa atcctggagg tggtgacctg cagaaagcag gaaagctctc tccacttaaa
541 gtgcagccta agaagcttcc ctgcagaggc cagactacct gccgaggatc ttgtgattct
601 ggagaactag gccgaaactc aggaacattt tcttcgcaga ttgagaatac acccatcctg
661 tgtccttttc atttgcaacc agtgcctgaa cctgaaacag tgttaaaaaa tcaagaagta
721 gaattcggca gaaatcgaga gaggcttcag ttttttaagt ggagttcaag agttttaaag
781 aatgtggcag tgatccctcc tggaactgga atggctcatc aaataaactt agaatatttg
841 tcaagagtgg tttttgaaga aaaagacctc ctcttcccag acagtgtagt cggcacagat
901 tcacacataa cgatggtgaa tggtttaggg attctggggt ggggggttgg aggcattgaa
961 acagaagcag ttatgcttgg tctgccagtt tctcttactt taccagaggt ggttggatgt
1021 gagttaactg ggtcatcaaa cccttttgtt acatccatag atgttgttct tggtattaca
1081 aagcacctca ggcaagtagg agtggctgga aagtttgttg agttttttgg aagtggagtt
1141 tcacaattat ctatagttga tcgaactaca atagcaaaca tgtgtccgga atatggtgct
1201 atcctcagct ttttccctgt tgacaatgtg acattaaaac atttagaaca tacaggtttt
1261 agcaaagcca aactcgaatc aatggaaaca taccttaaag ctgtgaaatt gtttcgaaat
1321 gaccagaatt cttcaggaga acctgaatac tcccaggtga tccagattaa tctgaattca
1381 atagttccat ctgttagtgg tccaaaaaga cctcaggata gagttgctgt gacagatatg
1441 aaaagcgatt tccaggcttg cttaaatgaa aaggttggat ttaaaggctt ccaaattgca
1501 gctgaaaaac aaaaggatat tgtctccatt cattatgaag gaagtgaata taagctgtct
1561 catggatcag tggtcattgc tgcagttatc agttgtacca ataattgcaa tccatctgtc
1621 atgcttgctg caggtctttt ggctaaaaag gctgttgaag ctggtctgcg tgttaaacct
1681 tatataagaa caagtttatc tccaggcagt gggatggtta cacattacct cagttcaagt
1741 ggagtattac catatctaag taagcttgga tttgaatcgt tggctatgga tgttcaactt
1801 gtgtgggaaa tacagcaccc ttatcagacg acgattttaa atgcagtaaa acagggtgat
1861 ttggttacct gtggaatttt atctggaaac aaaaattttg aaggtactga ccccaccggc
1921 aagaacattt acctgcatga tatttggcct agtcgagaag aagttcatcg agtagaggaa
1981 gaacatgtta tactatccat gtttaaagca ttaaaagata aaatagaaat ggggaataaa
2041 cggtggaatt ccttagaagc accggattca gttttgtttc catgggactt aaagtctact
2101 tatatcagat gcccttcatt ttttgataaa cttaccaaag agccaattgc actccaggct
2161 attgaaaatg cccatgtctt attatatttg ggagactctg tcacaacaga tcatatatca
2221 cctgcaggaa gtatcgctag gaatagtgct gccgctaagt atttgacaaa cagaggcctt
2281 acccctcgtg aattcaactc ttacggagct cgaagaggta atgatgctgt aatgacaaga
2341 ggcacttttg caaatatcaa gctttttaat aagtttattg gaaaaccagc tcctaaaaca
2401 attcattttc catcaggaca gacgctagat gtatttgagg ctgcagagct gtaccagaaa
2461 gaaggtatcc cactgattat tttagcagga aagaaatatg gttcaggaaa ctccagagac
2521 tgggctgcca aaggaccgta tttactgggt gtgaaagctg ttttggctga aagttatgaa
2581 aaaatacaca aagatcattt gattggaatt ggcatagctc cacttcagtt ccttccagga
2641 gaaaatgcag attccttggg cctctccggt agagaaacat tttctttaac atttcctgaa
2701 gaactgtctc ctggaattac attgaatata cagacaagca ctggaaaagt attcagcgtg
2761 attgcttcgt ttgaagatga tgtggaaata acattataca aacatggagg attattaaac
2821 tttgtggcac gaaaattctc atagtatcta cttaccatag atacctttca taactggtaa
2881 ctgcaaagcc ttttgtgctg gacccaggaa tccttaccat ggagcagcag atagtcccag
2941 tatactcact tatctcatcc atggatgtaa atgatgatga atcaacatag taactgaaat
3001 gaaatacttc ttgattttaa ataatatacg aatggtgcta ttaatattgc taaaatcaac
3061 gtgtgaagtg tgttgtggaa gagacctgta agtatggggg ggggcgatat tatcagacca
3121 ttttgtaaat aaaggcagaa tttgtgtact cagaccaccc cgtaaataag gcagaatttg
3181 tgttgaagat tcttatatga ataaccttac tggatttgtt tagttttgca ccaataaaac
3241 tgtgtactac tgtttgttgg tttaagagta gcagattgaa atataagaag ccagattaga
3301 ctctaaaatt gtggccattg gaatctcatt tataaatgga ccttttaagt atattaattc
3361 ctcttcagaa ttgagctgga cacatttggc attcttagtt tg
//