GenBank-Updates@genbank.bio.net (01/25/91)
LOCUS HUMSPC1 4190 bp ss-mRNA PRI 25-JAN-1991
DEFINITION Human muscle beta spectrin mRNA, 3' end.
ACCESSION M37884
KEYWORDS acetlycholine receptor; actin binding protein;
cytoskeleton protein; muscle beta spectrin; structural protein.
SOURCE Human fetal skeletal muscle, cDNA to mRNA, clone 6A.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4190)
AUTHORS Winkelmann,J.C., Costa,F.F., Linzie,B.L. and Forget,B.G.
TITLE beta spectrin in human skeletal muscle: Tissue-specific
differential processing of 3' beta spectrin pre-mRNA generates a
beta spectrin isoform with a unique carboxyl terminus
JOURNAL J. Biol. Chem. 265, 20449-20454 (1990)
STANDARD simple staff_review
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by J.C.Winkelmann, 21-AUG-1990.
University of Minnesota
Box 480 UMHC
516 Delaware Street SE
Minneapolis, MN 55455
FEATURES Location/Qualifiers
CDS <1..3825
/gene="spectrin"
/evidence=EXPERIMENTAL
/codon_start=1
/product="muscle beta spectrin"
misc_feature 3184..3184
/note="differential splice site"
/gene="spectrin"
BASE COUNT 973 a 1179 c 1374 g 664 t
ORIGIN Chromosome 14 q23-q24
1 gacttgctgg gggaagtcag ccagctgcag gccttcctgc aggatctgga tgacttccag
61 gcctggctct ccatcaccca gaaggctgtg gcctctgagg acatgcccga atccctccca
121 gaggctgagc agctcctgca gcagcatgca ggtatcaagg atgagattga cgggcaccaa
181 gacagctacc agcgtgttaa ggagtctggg gagaaagtga tccaaggcca gacggaccca
241 gagtatctgc ttctgggcca gcggctggag ggcctggata ctggctggga tgccctgggc
301 aggatgtggg agagccgcag ccacaccctc gctcagtgcc ttggcttcca ggagttccag
361 aaagatgcca agcaggctga agccatcctc agcaaccagg aatacactct ggctcacttg
421 gagcccccag actccctgga agctgcagag gctgggatcc ggaagtttga ggatttcttg
481 gggtctatgg agaacaaccg ggataaggtc ttgagtcctg tggactctgg aaacaagctg
541 gtagctgagg gaaacctata ctcagacaag atcaaggaga aggtgcagct gattgaggac
601 aggcacagga agaacaacga gaaggcccag gaggcctctg tcctactgag agacaacctg
661 gagctacaga acttcctcca gaactgccag gagctcactc tctggatcaa cgacaagctg
721 ctgacatctc aggatgtctc ctatgatgaa gcacgaaacc ttcacaataa atggctaaag
781 caccaggcgt ttgtggcaga gctggcttcc catgaagggt ggctagagaa catcgatgcg
841 gaaggaaagc agctgatgga tgagaagccc cagtttacag ccctggtgtc ccaaaagctg
901 gaagccctgc accggctctg ggacgagctg caggccacca caaaggagaa gacccagcac
961 ctctcggctg ccaggagctc cgacctgcgc ttgcagaccc atgctgacct caacaagtgg
1021 atcagcgcca tggaggacca gctgcgatca gacgacccgg gcaaggacct gaccagtgtc
1081 aatcggatgt tggctaagct gaagcgagtg gaggaccaag tgaatgtgcg gaaagaggag
1141 ctgggggagc tgtttgccca ggtgccttca atgggagagg agggaggaga tgcagacttg
1201 agcatcgaga agcggttcct ggacctcctg gaacccctag gaaggaggaa gaagcagctg
1261 gaatcatcca gagccaagct gcagatcagc cgggacttag aggatgagac gctttgggtg
1321 gaggagaggc tgcctctggc ccagtcagcc gactatggca ctaatctgca aactgtgcaa
1381 ctgttcatga agaagaacca gacactgcag aatgagattc tgggccatac gccgcgggtt
1441 gaggatgtgc tgcagagagg gcagcagctg gtggaggcgg cggagatcga ctgccaggac
1501 cttgaggagc gcctggggca cctgcagagc tcctgggaca ggctgcggga ggcagcggcc
1561 gggaggctgc agcgactgag ggacgccaat gaggcacagc agtactacct ggatgcggac
1621 gaggctgagg cctggattgg cgagcaggag ctctatgtca tctccgatga gatccccaag
1681 gatgaagagg gcgccatcgt gatgctgaag cgacatttgc ggcagcagcg tgcggtggag
1741 gactacggcc ggaacatcaa gcagctggcc agccgggccc agggcctgct gtctgcaggc
1801 caccctgagg gggaacagat catcagactt caggggcaag tggacaagca ctacgcaggg
1861 ctgaaggacg tggcggaaga gcgcaagcgc aagctggaga acatgtacca cctgttccag
1921 ctcaagcggg agaccgacga cctggagcag tggatttcag aaaaggagct agtggcctct
1981 tccccggaaa tggggcaaga ctttgaccac gtgactcttc tgcgggacaa gttccgggac
2041 tttgcccggg agaccggggc gattgggcag gagcgggtgg acaatgtgaa tgccttcatc
2101 gagcgactca tcgacgcggg ccacagcgag gcggccacca tcgccgagtg gaaggacggg
2161 ctgaacgaga tgtgggcaga cctcctggag ctcattgaca cgcgcatgca gctgctggcc
2221 gcctcctatg acctgcaccg ctacttctac acgggtgccg agatcctggg cctcatcgac
2281 gagaagcacc gcgagctgcc cgaggacgtg gggctggacg ccagcacggc cgagtccttc
2341 caccgggtgc acacagcctt cgagcgggac gttcacctgc tgggtgtcca ggtgcagcag
2401 ttccaggacg tggccacccg tctgcagaca gcatatgctg gggagaaggc agaggccatc
2461 cagaacaagg agcaggaggt gtctgccgcg tggcaggcgc tgctcgatgc ctgtgccggg
2521 cgccggaccc agctagtgga cacggcggat aaattccgct tcttcagcat ggcccgtgac
2581 ctcctctcct ggatggagag catcatccgg cagatcgaga cccaggagag gcccagggat
2641 gtctcctctg tggaactgct catgaagtat caccagggca tcaatgcaga gattgaaacc
2701 cggagcaaga acttcagtgc ctgcctggag cttggcgagt ccctgctgca gcggcagcac
2761 caggcctcag aggagatccg cgagaaactg cagcaggtga tgtccaggag gaaagagatg
2821 aatgagaagt gggaagcccg ctgggagcgg ctccgcatgt tgctggaggt gtgccagttc
2881 tcgagggatg cctctgtggc tgaggcgtgg ctgattgccc aggagcccta cctggccagc
2941 ggggactttg gacacacagt ggacagtgtg gagaagctca tcaagaggca tgaggctttt
3001 gagaagtcca cggccagctg ggcagagcgc tttgctgccc tggagaagcc caccacgctt
3061 gagctgaaag aacgccagat tgcagagaga cccgcagagg agactgggcc tcaagaggag
3121 gaaggcgaga cagcagggga ggctccagtt tcccaccatg cggccaccga gagaacgtcc
3181 ccgggggaag aagagggaac gtggcctcag aacctgcagc agccaccacc gccgggtcag
3241 cacaaggatg ggcagaaatc cactggggat gagaggccca ccacggagcc cctctttaag
3301 gtcctagata cgcctctgag cgagggtgat gagcccgcaa cgctgccggc cccgcgggac
3361 catgggcaga gtgtgcagat ggaaggctac ctgggccgca agcatgacct ggaggggccc
3421 aacaagaagg cttccaacag gtcctggaac aacctgtact gtgtgctcag gaacagtgag
3481 ctaaccttct acaaggatgc caagaacctg gccctgggga tgccctacca tggggaggaa
3541 cccctggccc tgagacatgc catctgtgag attgctgcca actacaagaa gaagaagcac
3601 gtctttaagc tgaggctgag taatggcagc gagtggctct tccatggcaa ggatgaggag
3661 gagatgctgt cctggctgca gggcgtgagc accgccatca acgagtccca gagcatccgc
3721 gtcaaggcgc agagcctgcc cctgccttcc ctctccggcc ccgacgccag cctcggcaag
3781 aaagacaagg agaagagatt cagcttcttc cccaaaaaga agtagcaggt ggggctggcg
3841 ggcgcggcgg agtcgggacg cgcagagacc gggcagccca ggccttggcc tcctctcgcc
3901 gccgcccgcc ggtcgaatcg agatgagtcg agtcgcgggc cgggcccccg ggccccacgc
3961 tgcactgcaa aagctgcctt cgcccgcgtg tcctgggccg acgccccctc catgccctcg
4021 cccgcgctgg ctccgctcca gggacagggg ctcccagctc ctctggcgcc tttggggcct
4081 ccaggcctgg gggcaggaaa cggttctctg aggcacacgc cctcctctcc caccctcctc
4141 ctgagccgag ggggcacagg ccccttaccc ccaaccaaaa aaaaaaaaaa
//