GenBank-Updates@genbank.bio.net (12/07/90)
LOCUS ECOCFAIA 7176 bp ds-DNA BCT 07-DEC-1990
DEFINITION E.coli CFA/I fimbrial operon cfa a, cfa b, cfa c, cfa e, cfa d'
genes, complete cds.
ACCESSION M55661
KEYWORDS colonisation factor antigen I; regulatory protein.
SOURCE Escherichia coli (enterotoxigenic) DNA.
ORGANISM Escherichia coli
Prokaryota; Bacteria; Gracilicutes; Scotobacteria;
Facultatively anaerobic rods; Enterobacteriaceae.
REFERENCE 1 (bases 1 to 7176)
AUTHORS Hamers,A.M., Pel,H.J., Willshaw,G.A., Kusters,J.G.,
van der Zeijst,B.A.M. and Gaastra,W.
TITLE The nucleotide sequence of the first two genes of the CFA/I
fimbrial operon of human enterotoxigenic Escherichia coli
JOURNAL Microb. Pathog. 6, 297-309 (1989)
STANDARD simple staff_entry
REFERENCE 2 (bases 1 to 7176)
AUTHORS Gaastra,W., Jordi,B.J.A.M., Mul,E.M.A., Hamers,A.M.,
McConnell,M.M., Willshaw,G.A., Smith,H.R. and van der Zeijst,B.A.M.
TITLE The silent regulatory gene cfaD' on region 1 of the CFA/I plasmid
NTP 113 of enterotoxigenic Escherichia coli
JOURNAL Unpublished (1990)
STANDARD simple staff_entry
FEATURES from to/span description
pept 848 1468 colonisation factor antigen I (cfa a)
precursor
sigp 848 904 colonisation factor antigen I signal peptide
matp 905 1465 colonisation factor antigen I
pept 1595 2107 colonisation factor antigen I (cfa b)
precursor
sigp 1595 1663 colonisation factor antigen I signal peptide
matp 1664 2104 colonisation factor antigen I
pept 2172 4781 colonisation factor antigen I (cfa c)
precursor
sigp 2172 2237 colonisation factor antigen I signal peptide
matp 2238 4778 colonisation factor antigen I
pept 4785 5867 colonisation factor antigen I (cfa e)
precursor
sigp 4785 4844 colonisation factor antigen I signal peptide
matp 4845 5864 colonisation factor antigen I
pept 6824 6390 (c) truncated CfaD-like protein with a stop codon
and frameshift deletions between bp 6029 and
6824.
BASE COUNT 2442 a 1129 c 1271 g 2333 t 1 others
ORIGIN
1 cttctctgct ctgrctgaag gtctgcagcc tcatcaactg agtgataaac aatcaactaa
61 aggagcactt atgagcgatg tattgttgtc tatggatacc tgtcaccagc tgctgcggat
121 gctgaaaaca cgccagtcag agtagttgac gtctaatagt taggggttca gatgagtggc
181 tcagcgtatg taccatttgc ttccatacgg atttaaacct caggcggaat aggtgataga
241 ttgtaaatct attcgtcatt atgttaactc aatttcaata tgcaaggcgg catagtgtgg
301 tgtcattttg ttaaaaactt tttaactttg tcgattttag caggccacaa acgacaaacc
361 ttcccgaagc cggtacccta gtgcttttcc tgataaatcg cctgtcagac tgatgtacac
421 ccaacctaac ggtgacatta agcattaatc ttcacgccta aaccttatgt gagaacggcg
481 ttgtacaacc ttgtagtggc gatgagcatt acaacgaaaa ttatccacat agtgcgttgg
541 gatatttctt attgaggaaa tatcggtgtc attaagtaac gttaacttaa gataaagaat
601 ctgtctggaa atcgcagggc caagaacact cagtacatct gtggcgataa tactatcgct
661 tcttattcat tccaatatgc agttcctgtg gatatttgct tgaacatcgc agcattagtg
721 agtgcacaga attatagcat cgataccaaa taacacaggt tacacaatga tttgtttgca
781 ttgtcttgtt tttttatctc attttttttt gttttgattt attattgatg gaagctcagg
841 aggaaatatg cataaattat tctatttact aagtttactc atggctccat ttgttgcaaa
901 tgcaaacttt atgatatatc caatatcaaa agatttaaag aatggaaata gcgagttagt
961 tcgtgtttat tcaaaatcaa aagagataca atatataaaa atatatacaa agaagattat
1021 taatcccggt acaactgaag aatataaggt tgatataccc aattgggatg gtgggcttgt
1081 agtcactcct cagaaagtta tcctccctgc aggagcgagt aaatcaatac gtttaactca
1141 atttaaaata ccaaaaaaag aggaagttta cagagtatat tttgaggcgg taaaaccaga
1201 tagcaaagaa aatgtaattg ataataaaaa actaacaaca gagctatctg ttaatataat
1261 ttatgcggct ctaattagat ctttaccaag tgaacaaaat atatcactaa atatttctag
1321 aaatgcaaaa aaaaatataa ttatttataa taatgggaat gttagagcag gcgttaaaga
1381 tatttatttt tgtaagtcat ctaatatcga tgataactgt gtaaaaaaag cgtataacaa
1441 gaatatatat ccagaaaaag tcatttgata cgctggttaa taacaatttt ttcttatgtt
1501 ttcattaaat taaaccatga aggcatagaa aaagagcaag ggctaataca attaaaggtt
1561 ccttgattac tcatctatat actaaggagt tctaatgaaa tttaaaaaaa ctattggtgc
1621 aatggctctg accacaatgt ttgtagcagt gagtgcttca gcagtagaga aaaatattac
1681 tgtaacagct agtgttgatc ctgcaattga tcttttgcaa gctgatggca atgctctgcc
1741 atcagctgta aagttagctt attctcccgc atcaaaaact tttgaaagtt acagagtaat
1801 gactcaagta catacaaacg atgcaactaa aaaagtaatt gttaaacttg ctgatacacc
1861 acagcttaca gatgttctga attcaactgt tcaaatgcct atcagtgtgt catggggagg
1921 acaagtatta tctacaacag ccaaagaatt tgaagctgct gctttgggat attctgcatc
1981 cggtgtaaat ggcgtatcat cttctcaaga gttagtaatt agcgctgcac ctaaaactgc
2041 cggtaccgcc ccaactgcag gaaactattc aggagtagta tctcttgtaa tgactttggg
2101 atcctgattc ttttatttaa aaggaggggg tatgtttata catccctcct ttttcatgga
2161 aatgaattta tatgaagcat aaaaaaaaga atagattagt cgtagcgatt tcagttgcat
2221 taattccata tataggggtt accggagata tacccgactc tttccgtgat ttatggggag
2281 aacaagatga attttatgaa gtaaaactat atgggcaaac tctaggaata catcgaatta
2341 aaacaacccc aacacatatt aagttttatt cacccgaaag cattttagat aaaataaatt
2401 taaaaaaaga aaaggaaaag gaattgagtg ttttttttac taattctttt tcaagaaatg
2461 gcaatatgag ttgtcagggt aacactacta tacagtataa ctgcaattac attaaaacaa
2521 aatcagtaga tgtcatcgtt gatgatgttg ataatgttgt taaccttttt ataggtaatg
2581 aatttctgga ttctgaagca cacaatgatg aatatcatca attatcacgg aatgtaaaaa
2641 aagcttttat acaaagccag acaattaatc tctcagattc tggaaagtat aaaagattgt
2701 ctatttcagg gaatagcgcg ctgggtatta cagatacaag ttatgctgtc ttaaattggt
2761 ggatgaatta caataaatct aatggttaca gcaacaacga aaaaacaatc aatagtttat
2821 actttagaca tgatttagat aagagatatt attatcaatt tggacgaatg gatcgtacag
2881 atttatcaca aagtattagc gggagcttta attttaactt acttccttta cccgatattg
2941 atggtatacg gacaggaacc acacaatctt atatcaaaaa tacagataag tttatcgcat
3001 cccctgtaac tgttatgtta actaattttt ccagagtgga agcttttcgc aatgatcaat
3061 tattgggcgt atggtattta gattctggag taaatgaatt agatacagct cgtttacctt
3121 atggcagtta cgatcttaaa ttaaaaattt ttgaaaacac tcaattagtt cgtgaagaaa
3181 taattccttt taataaagga agaagctcta ttggtgatat gcaatgggat attttcgttc
3241 agggagggaa tattgttaat gataatgatc gttacataga aaaacaaaat aatcataagt
3301 catcgattaa tactgggcta cgtttaccaa ttacgaaaaa tatctctgtt caacagggag
3361 tatctgttat agataataaa agttattatg aaggaagtct gaaatggaat tccggcattc
3421 tatctggctc actaaatagt gagttcagtt ttctttgggg agataatgca aaaggtaatt
3481 atcaaagtat ctcgtatacc gatggattta gcttatcatt ttatcataat gataagcggg
3541 tcgataattg tggaagaaat tacaatgctg gttggagtgg atgctacgaa tcatattcgg
3601 catctttaag tattccttta ttaggatgga caagtactct gggatatagt gacacttata
3661 gtgaatcagt gtataaaagc catattcttt ctgaatatgg cttttataat caaaacatat
3721 ataaagggag aacccaaaga tggcaactga cttcatccac ctctttaaaa tggatggatt
3781 ataattttat gccagcaatt ggaatatata acagtgaaca aagacaactg actgataaag
3841 gcggatatat atctgtaact atcacccgag ccagcagaga aaattcatta aatacagggt
3901 attcttacaa ctattccaga ggaaactatt cttctaacga attatttgtt gatggatata
3961 tgacatcaac aaataatggt gattatcatg aggcaggaat gcgttttaat aaaaatagac
4021 ataatgcaga aggtagactt tcaggtcgta taaacaatcg atttggagat ttaaatggtt
4081 cattcagcat gaataaaaac agaaacacca acagtaccaa tcattctctc actggtggtt
4141 ataattcctc atttgctctt acaagtgatg gattttactg gggaggaagt acagctggtt
4201 tgacaaaact ggctggcggt attatcaagg ttaaatcaaa cgatactaaa aaaaacttgg
4261 taaaagtgac tgggacattg tacggtgatt attcgctagg gagcaacgat aatgctttta
4321 ttcctgtacc agcattaact ccagccagtt taatcattga agataataat tatggtgata
4381 ataatatttc tatacttgcg ccaacaaaca acgatatgtt tatgttgccg ggtaatgttt
4441 atcctgttga aattgaaacc aaagtaagtg tttcttatat tggtagaggt tttgacccaa
4501 acggcacgcc actttctggc gcacatgttt tgaatgaacc acatgttatc ctggatgagg
4561 acggtggatt ttcgtttgaa tatacaggta atgagaaaac acttttttta ttaaagggca
4621 ggactattta tacatgtcaa ctggggaaaa ataaagttca taaaggcatt gttttcgtcg
4681 gggatgttat atgtgatatt aatagcacaa gttccttacc agatgaattt gtaaagaacc
4741 cacgtgtgca ggatttgctg gcaaagaatg ataaaggata aacgatgaat aaaattttat
4801 ttatttttac attgtttttt tcttcagggt tttttacatt tgccgtatcg gcagataaaa
4861 atcccggaag tgaaaacatg actaatacta ttggtcccca tgacaggggg ggatcttccc
4921 ccatatataa tatcttaaat tcctatctta cagcatacaa tggaagccat catctgtatg
4981 ataggatgag ttttttatgt ttgtcttctc aaaatacact gaatggagca tgcccaagca
5041 gtgatgcccc tggcactgct acaattgatg gcgaaacaaa tataacatta caatttacgg
5101 aaaaaagaag tctaattaaa agagaactgc aaattaaagg ctataaacaa tttttgttca
5161 aaaatgctaa ttgcccatct aaactagcac ttaactcatc tcattttcaa tgtaatagag
5221 aacaagcttc aggtgctact ttatcgttat acataccagc tggtgaatta aataaattac
5281 cttttggggg ggtctggaat gccgttctga agctaaatgt aaaaagacga tatgatacaa
5341 cctatgggac ttacactata aacatcacag ttaatttaac tgataaggga aatattcaga
5401 tatggttacc acagttcaaa agtaacgctc gtgtcgatct taacttgcgt ccaactggtg
5461 gtggtacata tatcggaaga aattctgttg atatgtgctt ttatgatgga tatagtacta
5521 acagcagctc tttggagata agatttcagg atgataattc taaatctgat ggaaaatttt
5581 atctaaagaa aataaatgat gactccaaag aacttgtata cactttgtca cttctcctgg
5641 caggtaaaaa tttaacacca acaaatggac aggcattaaa tattaacact gcttctctgg
5701 aaacaaactg gaatagaatt acagctgtca ccatgccaga aatcagtgtt ccggtgttgt
5761 gttggcctgg acgtttgcaa ttggatgcaa aagtgaaaaa tcccgaggct ggacaatata
5821 tggggaatat taaaattact ttcacaccaa gtagtcaaac actctagata acaacatatt
5881 ggcgctattg ccggccaata ttgtaaatag gtaatctgtt tgttaacaaa acattttatt
5941 tcaattcagt ttgcgtcgca ataaatctct actagagaca tttttataca gcatagtatt
6001 atgcaacaca ttcaaaataa agtaattttt atcctccttt aaaataagta aaaaactgct
6061 ttggtgcaac accataatgt ttattaaaaa ccctaataaa ataagatata ctagaaattc
6121 caatcatatt tgatatctgt gatatctggt atggattttc aagcagcaat aacgcagcct
6181 tgctcattct cgattgcatt aagatctggt taaaattagt attctcagat tctagtcttt
6241 tcctgatggt tatttctgat acattaaacg tatctgcaat aatagccaaa gtccattttc
6301 tggatagatc tttttcgata acactcctga ccttatcaga aaaaaattca cagatgatat
6361 ataaattgat tctattattt ttcattattc taaatttttg aaatcaaata tatcagacta
6421 gatataaaaa ctgagtcatc ataactattt atatttttta atacatccag taaggtttta
6481 tctacttctg ttttaattat ttttcttgac atatttctac aatcattgat atctattttt
6541 gacatgccat atattatcat taatgcattc tttaaatgtc ttagtatgtc tccgttcaat
6601 ctgaatgcaa tatatggttt ttctgataaa atttgcttct gtattcttac agatatattt
6661 actcctcttt caagaaatac aagtctgtta ctagaacatg tgattttctc ttcttctgaa
6721 tatatatcca taatacaatt tgatgtatat aatacagtgt atatatgaat cataatatta
6781 ttaattttta tcatttcttt ttcttcagtg tatttaaaat ccatcttata cctacaaaag
6841 gcaagaggtt tgatttgctt gtacaatcac cttttgaaca gttggcctaa cttttgctaa
6901 aagaaagata tgttttttca acttttttgc tttttttatt attgtatctt tttgatgctt
6961 ttctgtgatg tacacttatg tgtgattaat gttttatcgg agatagtgtt tcaatggaaa
7021 taaaagagtg ttttcatgtt ttatcaaaaa aagccgctct ggcagaaaaa aacatggatt
7081 tagtttctgc atttgaactt tggaaacaag catcactttt gtgtaaaaac gctaaaaata
7141 tagactggtg cataaataga gcaatgtttt gtgaag
//GenBank-Updates@genbank.bio.net (01/31/91)
LOCUS ECOCFAIA 7176 bp ds-DNA BCT 31-JAN-1991
DEFINITION E.coli CFA/I fimbrial operon cfa a, cfa b, cfa c, cfa e, cfa d'
genes, complete cds.
ACCESSION M55661
KEYWORDS colonisation factor antigen I; regulatory protein.
SOURCE Escherichia coli (enterotoxigenic) DNA.
ORGANISM NTP 513
E7473.
REFERENCE 1 (bases 1 to 7176)
AUTHORS Hamers,A.M., Pel,H.J., Willshaw,G.A., Kusters,J.G., van der
Zeijst,B.A. and Gaastra,W.
TITLE The nucleotide sequence of the first two genes of the CFA/I
fimbrial operon of human enterotoxigenic Escherichia coli
JOURNAL Microb. Pathog. 6, 297-309 (1989)
STANDARD simple staff_entry
REFERENCE 2 (bases 1 to 7176)
AUTHORS Gaastra,W., Jordi,B.J., Mul,E.M., Hamers,A.M., McConnell,M.M.,
Willshaw,G.A., Smith,H.R. and van der Zeijst,B.A.
TITLE A silent regulatory gene cfaD' on region 1 of the CFA/I plasmid NTP
113 of enterotoxigenic Escherichia coli
JOURNAL Unpublished (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 848..1468
/product="colonisation factor antigen a"
/gene="cfa a"
/codon_start=848
sig_peptide 848..904
/gene="cfa a"
/codon_start=848
mat_peptide 905..1465
/product="colonisation factor antigen a"
/gene="cfa a"
/codon_start=905
CDS 1595..2107
/product="colonisation factor antigen b"
/gene="cfa b"
/codon_start=1595
sig_peptide 1595..1663
/gene="cfa b"
/codon_start=1595
mat_peptide 1664..2104
/product="colonisation factor antigen b"
/gene="cfa b"
/codon_start=1664
CDS 2172..4781
/product="colonisation factor antigen c"
/gene="cfa c"
/codon_start=2172
sig_peptide 2172..2237
/gene="cfa c"
/codon_start=2172
mat_peptide 2238..4778
/product="colonisation factor antigen c"
/gene="cfa c"
/codon_start=2238
CDS 4785..5867
/note="unpublished sequence"
/product="colonisation factor antigen e"
/gene="cfa e"
/codon_start=4785
sig_peptide 4785..4844
/gene="cfa e"
/codon_start=4785
mat_peptide 4845..5864
/product="colonisation factor antigen e"
/gene="cfa e"
/codon_start=4845
CDS complement(6390..6824)
/note="truncated CfaD-like protein with a stop codon and
frameshift deletions between bp 6029 and 6824."
/product="colonisation factor antigen d'"
/gene="cfa d'"
/codon_start=6390
BASE COUNT 2442 a 1129 c 1271 g 2333 t 1 others
ORIGIN
1 cttctctgct ctgrctgaag gtctgcagcc tcatcaactg agtgataaac aatcaactaa
61 aggagcactt atgagcgatg tattgttgtc tatggatacc tgtcaccagc tgctgcggat
121 gctgaaaaca cgccagtcag agtagttgac gtctaatagt taggggttca gatgagtggc
181 tcagcgtatg taccatttgc ttccatacgg atttaaacct caggcggaat aggtgataga
241 ttgtaaatct attcgtcatt atgttaactc aatttcaata tgcaaggcgg catagtgtgg
301 tgtcattttg ttaaaaactt tttaactttg tcgattttag caggccacaa acgacaaacc
361 ttcccgaagc cggtacccta gtgcttttcc tgataaatcg cctgtcagac tgatgtacac
421 ccaacctaac ggtgacatta agcattaatc ttcacgccta aaccttatgt gagaacggcg
481 ttgtacaacc ttgtagtggc gatgagcatt acaacgaaaa ttatccacat agtgcgttgg
541 gatatttctt attgaggaaa tatcggtgtc attaagtaac gttaacttaa gataaagaat
601 ctgtctggaa atcgcagggc caagaacact cagtacatct gtggcgataa tactatcgct
661 tcttattcat tccaatatgc agttcctgtg gatatttgct tgaacatcgc agcattagtg
721 agtgcacaga attatagcat cgataccaaa taacacaggt tacacaatga tttgtttgca
781 ttgtcttgtt tttttatctc attttttttt gttttgattt attattgatg gaagctcagg
841 aggaaatatg cataaattat tctatttact aagtttactc atggctccat ttgttgcaaa
901 tgcaaacttt atgatatatc caatatcaaa agatttaaag aatggaaata gcgagttagt
961 tcgtgtttat tcaaaatcaa aagagataca atatataaaa atatatacaa agaagattat
1021 taatcccggt acaactgaag aatataaggt tgatataccc aattgggatg gtgggcttgt
1081 agtcactcct cagaaagtta tcctccctgc aggagcgagt aaatcaatac gtttaactca
1141 atttaaaata ccaaaaaaag aggaagttta cagagtatat tttgaggcgg taaaaccaga
1201 tagcaaagaa aatgtaattg ataataaaaa actaacaaca gagctatctg ttaatataat
1261 ttatgcggct ctaattagat ctttaccaag tgaacaaaat atatcactaa atatttctag
1321 aaatgcaaaa aaaaatataa ttatttataa taatgggaat gttagagcag gcgttaaaga
1381 tatttatttt tgtaagtcat ctaatatcga tgataactgt gtaaaaaaag cgtataacaa
1441 gaatatatat ccagaaaaag tcatttgata cgctggttaa taacaatttt ttcttatgtt
1501 ttcattaaat taaaccatga aggcatagaa aaagagcaag ggctaataca attaaaggtt
1561 ccttgattac tcatctatat actaaggagt tctaatgaaa tttaaaaaaa ctattggtgc
1621 aatggctctg accacaatgt ttgtagcagt gagtgcttca gcagtagaga aaaatattac
1681 tgtaacagct agtgttgatc ctgcaattga tcttttgcaa gctgatggca atgctctgcc
1741 atcagctgta aagttagctt attctcccgc atcaaaaact tttgaaagtt acagagtaat
1801 gactcaagta catacaaacg atgcaactaa aaaagtaatt gttaaacttg ctgatacacc
1861 acagcttaca gatgttctga attcaactgt tcaaatgcct atcagtgtgt catggggagg
1921 acaagtatta tctacaacag ccaaagaatt tgaagctgct gctttgggat attctgcatc
1981 cggtgtaaat ggcgtatcat cttctcaaga gttagtaatt agcgctgcac ctaaaactgc
2041 cggtaccgcc ccaactgcag gaaactattc aggagtagta tctcttgtaa tgactttggg
2101 atcctgattc ttttatttaa aaggaggggg tatgtttata catccctcct ttttcatgga
2161 aatgaattta tatgaagcat aaaaaaaaga atagattagt cgtagcgatt tcagttgcat
2221 taattccata tataggggtt accggagata tacccgactc tttccgtgat ttatggggag
2281 aacaagatga attttatgaa gtaaaactat atgggcaaac tctaggaata catcgaatta
2341 aaacaacccc aacacatatt aagttttatt cacccgaaag cattttagat aaaataaatt
2401 taaaaaaaga aaaggaaaag gaattgagtg ttttttttac taattctttt tcaagaaatg
2461 gcaatatgag ttgtcagggt aacactacta tacagtataa ctgcaattac attaaaacaa
2521 aatcagtaga tgtcatcgtt gatgatgttg ataatgttgt taaccttttt ataggtaatg
2581 aatttctgga ttctgaagca cacaatgatg aatatcatca attatcacgg aatgtaaaaa
2641 aagcttttat acaaagccag acaattaatc tctcagattc tggaaagtat aaaagattgt
2701 ctatttcagg gaatagcgcg ctgggtatta cagatacaag ttatgctgtc ttaaattggt
2761 ggatgaatta caataaatct aatggttaca gcaacaacga aaaaacaatc aatagtttat
2821 actttagaca tgatttagat aagagatatt attatcaatt tggacgaatg gatcgtacag
2881 atttatcaca aagtattagc gggagcttta attttaactt acttccttta cccgatattg
2941 atggtatacg gacaggaacc acacaatctt atatcaaaaa tacagataag tttatcgcat
3001 cccctgtaac tgttatgtta actaattttt ccagagtgga agcttttcgc aatgatcaat
3061 tattgggcgt atggtattta gattctggag taaatgaatt agatacagct cgtttacctt
3121 atggcagtta cgatcttaaa ttaaaaattt ttgaaaacac tcaattagtt cgtgaagaaa
3181 taattccttt taataaagga agaagctcta ttggtgatat gcaatgggat attttcgttc
3241 agggagggaa tattgttaat gataatgatc gttacataga aaaacaaaat aatcataagt
3301 catcgattaa tactgggcta cgtttaccaa ttacgaaaaa tatctctgtt caacagggag
3361 tatctgttat agataataaa agttattatg aaggaagtct gaaatggaat tccggcattc
3421 tatctggctc actaaatagt gagttcagtt ttctttgggg agataatgca aaaggtaatt
3481 atcaaagtat ctcgtatacc gatggattta gcttatcatt ttatcataat gataagcggg
3541 tcgataattg tggaagaaat tacaatgctg gttggagtgg atgctacgaa tcatattcgg
3601 catctttaag tattccttta ttaggatgga caagtactct gggatatagt gacacttata
3661 gtgaatcagt gtataaaagc catattcttt ctgaatatgg cttttataat caaaacatat
3721 ataaagggag aacccaaaga tggcaactga cttcatccac ctctttaaaa tggatggatt
3781 ataattttat gccagcaatt ggaatatata acagtgaaca aagacaactg actgataaag
3841 gcggatatat atctgtaact atcacccgag ccagcagaga aaattcatta aatacagggt
3901 attcttacaa ctattccaga ggaaactatt cttctaacga attatttgtt gatggatata
3961 tgacatcaac aaataatggt gattatcatg aggcaggaat gcgttttaat aaaaatagac
4021 ataatgcaga aggtagactt tcaggtcgta taaacaatcg atttggagat ttaaatggtt
4081 cattcagcat gaataaaaac agaaacacca acagtaccaa tcattctctc actggtggtt
4141 ataattcctc atttgctctt acaagtgatg gattttactg gggaggaagt acagctggtt
4201 tgacaaaact ggctggcggt attatcaagg ttaaatcaaa cgatactaaa aaaaacttgg
4261 taaaagtgac tgggacattg tacggtgatt attcgctagg gagcaacgat aatgctttta
4321 ttcctgtacc agcattaact ccagccagtt taatcattga agataataat tatggtgata
4381 ataatatttc tatacttgcg ccaacaaaca acgatatgtt tatgttgccg ggtaatgttt
4441 atcctgttga aattgaaacc aaagtaagtg tttcttatat tggtagaggt tttgacccaa
4501 acggcacgcc actttctggc gcacatgttt tgaatgaacc acatgttatc ctggatgagg
4561 acggtggatt ttcgtttgaa tatacaggta atgagaaaac acttttttta ttaaagggca
4621 ggactattta tacatgtcaa ctggggaaaa ataaagttca taaaggcatt gttttcgtcg
4681 gggatgttat atgtgatatt aatagcacaa gttccttacc agatgaattt gtaaagaacc
4741 cacgtgtgca ggatttgctg gcaaagaatg ataaaggata aacgatgaat aaaattttat
4801 ttatttttac attgtttttt tcttcagggt tttttacatt tgccgtatcg gcagataaaa
4861 atcccggaag tgaaaacatg actaatacta ttggtcccca tgacaggggg ggatcttccc
4921 ccatatataa tatcttaaat tcctatctta cagcatacaa tggaagccat catctgtatg
4981 ataggatgag ttttttatgt ttgtcttctc aaaatacact gaatggagca tgcccaagca
5041 gtgatgcccc tggcactgct acaattgatg gcgaaacaaa tataacatta caatttacgg
5101 aaaaaagaag tctaattaaa agagaactgc aaattaaagg ctataaacaa tttttgttca
5161 aaaatgctaa ttgcccatct aaactagcac ttaactcatc tcattttcaa tgtaatagag
5221 aacaagcttc aggtgctact ttatcgttat acataccagc tggtgaatta aataaattac
5281 cttttggggg ggtctggaat gccgttctga agctaaatgt aaaaagacga tatgatacaa
5341 cctatgggac ttacactata aacatcacag ttaatttaac tgataaggga aatattcaga
5401 tatggttacc acagttcaaa agtaacgctc gtgtcgatct taacttgcgt ccaactggtg
5461 gtggtacata tatcggaaga aattctgttg atatgtgctt ttatgatgga tatagtacta
5521 acagcagctc tttggagata agatttcagg atgataattc taaatctgat ggaaaatttt
5581 atctaaagaa aataaatgat gactccaaag aacttgtata cactttgtca cttctcctgg
5641 caggtaaaaa tttaacacca acaaatggac aggcattaaa tattaacact gcttctctgg
5701 aaacaaactg gaatagaatt acagctgtca ccatgccaga aatcagtgtt ccggtgttgt
5761 gttggcctgg acgtttgcaa ttggatgcaa aagtgaaaaa tcccgaggct ggacaatata
5821 tggggaatat taaaattact ttcacaccaa gtagtcaaac actctagata acaacatatt
5881 ggcgctattg ccggccaata ttgtaaatag gtaatctgtt tgttaacaaa acattttatt
5941 tcaattcagt ttgcgtcgca ataaatctct actagagaca tttttataca gcatagtatt
6001 atgcaacaca ttcaaaataa agtaattttt atcctccttt aaaataagta aaaaactgct
6061 ttggtgcaac accataatgt ttattaaaaa ccctaataaa ataagatata ctagaaattc
6121 caatcatatt tgatatctgt gatatctggt atggattttc aagcagcaat aacgcagcct
6181 tgctcattct cgattgcatt aagatctggt taaaattagt attctcagat tctagtcttt
6241 tcctgatggt tatttctgat acattaaacg tatctgcaat aatagccaaa gtccattttc
6301 tggatagatc tttttcgata acactcctga ccttatcaga aaaaaattca cagatgatat
6361 ataaattgat tctattattt ttcattattc taaatttttg aaatcaaata tatcagacta
6421 gatataaaaa ctgagtcatc ataactattt atatttttta atacatccag taaggtttta
6481 tctacttctg ttttaattat ttttcttgac atatttctac aatcattgat atctattttt
6541 gacatgccat atattatcat taatgcattc tttaaatgtc ttagtatgtc tccgttcaat
6601 ctgaatgcaa tatatggttt ttctgataaa atttgcttct gtattcttac agatatattt
6661 actcctcttt caagaaatac aagtctgtta ctagaacatg tgattttctc ttcttctgaa
6721 tatatatcca taatacaatt tgatgtatat aatacagtgt atatatgaat cataatatta
6781 ttaattttta tcatttcttt ttcttcagtg tatttaaaat ccatcttata cctacaaaag
6841 gcaagaggtt tgatttgctt gtacaatcac cttttgaaca gttggcctaa cttttgctaa
6901 aagaaagata tgttttttca acttttttgc tttttttatt attgtatctt tttgatgctt
6961 ttctgtgatg tacacttatg tgtgattaat gttttatcgg agatagtgtt tcaatggaaa
7021 taaaagagtg ttttcatgtt ttatcaaaaa aagccgctct ggcagaaaaa aacatggatt
7081 tagtttctgc atttgaactt tggaaacaag catcactttt gtgtaaaaac gctaaaaata
7141 tagactggtg cataaataga gcaatgtttt gtgaag
//