GenBank-Updates@genbank.bio.net (12/08/90)
LOCUS RATNCPR4 2510 bp ds-DNA ROD 08-DEC-1990
DEFINITION Rat NADPH-cytochrome P-450 oxidoreductase gene, exons 5-10.
ACCESSION M58935
KEYWORDS NADPH-cytochrome P-450 oxidoreductase.
SEGMENT 4 of 6
SOURCE Rat (strain: Wistar) DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2510)
AUTHORS Porter,T.D., Beck,T.W. and Kasper,C.B.
TITLE NADPH-cytochrome P-450 oxidoreductase gene organization correlates
with structural domains of the protein
JOURNAL Biochemistry 29, 9814-9818 (1990)
STANDARD simple staff_entry
FEATURES from to/span description
pept + 26 175 NADPH-cytochrome P-450 oxireductase, exon 5
587 711 NADPH-cytochrome P-450 oxireductase, exon 6
803 892 NADPH-cytochrome P-450 oxireductase, exon 7
1287 1385 NADPH-cytochrome P-450 oxireductase, exon 8
2162 2278 NADPH-cytochrome P-450 oxireductase, exon 9
2367 + 2485 NADPH-cytochrome P-450 oxireductase, exon 10
pre-msg < 1 > 2510 NADPH-cytochrome P-450 oxireductase mRNA and
introns
IVS < 1 25 NADPH-cytochrome P-450 oxireductase intron 4
IVS 176 586 NADPH-cytochrome P-450 oxireductase intron 5
IVS 712 802 NADPH-cytochrome P-450 oxireductase intron 6
IVS 893 1286 NADPH-cytochrome P-450 oxireductase intron 7
IVS 1386 2161 NADPH-cytochrome P-450 oxireductase intron 8
IVS 2279 2366 NADPH-cytochrome P-450 oxireductase intron 9
(no splice consensus)
IVS 2486 > 2510 NADPH-cytochrome P-450 oxireductase intron 10
BASE COUNT 513 a 755 c 674 g 568 t
ORIGIN
1 agtggtgaca cccctgtctc tctaggccga cctgagcagc ctgcctgaga tcgacaagtc
61 cctggtagtc ttctgcatgg ccacatacgg agagggcgac cccacggaca atgcgcagga
121 cttctatgac tggctgcagg agactgacgt ggacctcact ggggtcaagt ttgctgtgag
181 tctccacaga atcctgtggc agctcccccg agcactaggc ctccctgtgc aaactgtgtc
241 tccctctgtt aataaacaat gtgacagggc aggtagcttc agcttagcct gatccttact
301 ctggtggagc ctcacccaga gcggcccctc ccatgctact atctgatccc cagaacattg
361 gctactggat gcaaagccaa aagcaccgga gcctccagct aagctgggct gagacatagc
421 ctggttgtaa aaggcgctac ctgggctgca ggtctcctaa ataaagccat cagctgttcc
481 tctcagggcg cataaagcca gactgtgggt gaaggataca gtccacccca aggacatcag
541 atggcgtgaa gtcccatcct cagagcctcc cctgttgtcc acacaggtat ttggtcttgg
601 gaacaagacc tatgagcact tcaatgccat gggcaagtat gtggaccagc ggctggagca
661 gcttggcgcc cagcgcatct ttgagttggg ccttggtgat gatgacggga agtgagtgcc
721 acaccccagt cacgggtcta gcctggcatg tgggcctccc tcttacccct agcctcgcta
781 accctctcct ccctctctcc agcttggaag aggatttcat cacgtggagg gagcagttct
841 ggccagctgt gtgcgagttc tttggggtag aagccactgg ggaggagtcg aggtaagtgg
901 aaggccacag ctagggcccc ggctgggtgg ccctggggac acagtgaggt gtgggggtcg
961 gcaagagctc aagcatagat gaagaagccc ccagaaggtg agggggatga ggtggggtct
1021 ccctttctgt cctgtgcgtt cgctaggaca ctggctttcc tcccaccagt gcttcctggc
1081 cagctagtcc tctcaggctc tcggggtcag cctcagccct tctcctgcct ttgcttctct
1141 gtgtgtctgc tacagggtcc cctgcgtcct aatgtcactt gtcttccgtc catatcccct
1201 ttagctcaag ccctttctct ctctggctga ccctgaagct tcccccttcc cagccctgac
1261 cacagccttg gtttttccat tcccagcatt cgccagtatg agctcgtggt ccacgaagac
1321 atggacgcag ccaaggtgta cacgggtgag atgggccgtc tgaagagcta cgagaaccag
1381 aaaccgtgag tggaggaagc ggggtgggac ggacagctct ggggcccttg agtacccaca
1441 gcccagggag atgtgtgatc ctctggagtc ctctgaatga gcacagtggg gtccccacac
1501 tttcatgccc tctatcagga agggtacaag ctgcccaagg gacaggtgct cttccccacg
1561 caggccttag gagccaagcc ctgccatatt aaacttgggc aaaaagtccc attctgtcct
1621 tagagtccac tgccattggg catgcagctc agctggcgag tgcttccata acccgtgagg
1681 ccccggggtc cgtccccagg accgcacaga ctgggcgtgg tacacacacc tttgagctca
1741 gcacactcgg ggaaggaagt ccagttctct tatcctcagc tgcatagcgg ggttcaaggc
1801 aagccgggga tgcacgaaaa gtccaaacca ttccgttcac tttgacccct ccatccctct
1861 gggtgctgcc cagattcacg ctggaaccct ccttagtcat cgtggtctcc tggggtcaag
1921 ccagccatcc tgctgggtca gactcctcca cttgtcactc ctagccacac tgtggtccct
1981 gaatgtgagt gtgaaaacca aatggcatgc agtggtctca ggacttggca gctccactcc
2041 gctcaagtcc cccataggca gagggtctca aattttatag gaaccaggcc tgtgtgtccc
2101 ttcgctttgc ccatcttact acattcatgg gcaaatcact ggcctcctct tttcccatca
2161 gccccttcga tgctaagaat ccattcctgg ctgctgtcac cgccaaccgg aagctgaacc
2221 aaggcactga gcggcatcta atgcacctgg agttggacat ctcagactcc aagatcaggt
2281 acctgccgcc tcccatctcc ctgtggtaag cctggccctg aggcatctgg tggcttcctc
2341 ctgagccttg cacttccttc ctctaggtat gaatctggag atcacgtggc tgtgtaccca
2401 gccaatgact cagccctggt caaccagatt ggggagatcc tgggagctga cctggatgtc
2461 atcatgtctc taaacaatct cgatggtaag ttccagaatt gagggccttg
//GenBank-Updates@genbank.bio.net (01/31/91)
LOCUS RATNCPR4 2510 bp ds-DNA ROD 31-JAN-1991
DEFINITION Rat NADPH-cytochrome P-450 oxidoreductase gene, exons 5-10.
ACCESSION M58935
KEYWORDS NADPH-cytochrome P-450 oxidoreductase.
SEGMENT 4 of 6
SOURCE Rat (strain: Wistar) DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2510)
AUTHORS Porter,T.D., Beck,T.W. and Kasper,C.B.
TITLE NADPH-cytochrome P-450 oxidoreductase gene organization correlates
with structural domains of the protein
JOURNAL Biochemistry 29, 9814-9818 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron order(M58934:155..>179,<1..25)
/number=4
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 26..175
/number=5
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
intron 176..586
/number=5
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 587..711
/number=6
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
intron 712..802
/number=6
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 803..892
/number=7
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
intron 893..1286
/number=7
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 1287..1385
/number=8
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
intron 1386..2161
/number=8
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 2162..2278
/number=9
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
intron 2279..2366
/number=9
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
exon 2367..2485
/number=10
/gene="NADPH-cytochrome P-450 oxidoreductase gene"
BASE COUNT 513 a 755 c 674 g 568 t
ORIGIN
1 agtggtgaca cccctgtctc tctaggccga cctgagcagc ctgcctgaga tcgacaagtc
61 cctggtagtc ttctgcatgg ccacatacgg agagggcgac cccacggaca atgcgcagga
121 cttctatgac tggctgcagg agactgacgt ggacctcact ggggtcaagt ttgctgtgag
181 tctccacaga atcctgtggc agctcccccg agcactaggc ctccctgtgc aaactgtgtc
241 tccctctgtt aataaacaat gtgacagggc aggtagcttc agcttagcct gatccttact
301 ctggtggagc ctcacccaga gcggcccctc ccatgctact atctgatccc cagaacattg
361 gctactggat gcaaagccaa aagcaccgga gcctccagct aagctgggct gagacatagc
421 ctggttgtaa aaggcgctac ctgggctgca ggtctcctaa ataaagccat cagctgttcc
481 tctcagggcg cataaagcca gactgtgggt gaaggataca gtccacccca aggacatcag
541 atggcgtgaa gtcccatcct cagagcctcc cctgttgtcc acacaggtat ttggtcttgg
601 gaacaagacc tatgagcact tcaatgccat gggcaagtat gtggaccagc ggctggagca
661 gcttggcgcc cagcgcatct ttgagttggg ccttggtgat gatgacggga agtgagtgcc
721 acaccccagt cacgggtcta gcctggcatg tgggcctccc tcttacccct agcctcgcta
781 accctctcct ccctctctcc agcttggaag aggatttcat cacgtggagg gagcagttct
841 ggccagctgt gtgcgagttc tttggggtag aagccactgg ggaggagtcg aggtaagtgg
901 aaggccacag ctagggcccc ggctgggtgg ccctggggac acagtgaggt gtgggggtcg
961 gcaagagctc aagcatagat gaagaagccc ccagaaggtg agggggatga ggtggggtct
1021 ccctttctgt cctgtgcgtt cgctaggaca ctggctttcc tcccaccagt gcttcctggc
1081 cagctagtcc tctcaggctc tcggggtcag cctcagccct tctcctgcct ttgcttctct
1141 gtgtgtctgc tacagggtcc cctgcgtcct aatgtcactt gtcttccgtc catatcccct
1201 ttagctcaag ccctttctct ctctggctga ccctgaagct tcccccttcc cagccctgac
1261 cacagccttg gtttttccat tcccagcatt cgccagtatg agctcgtggt ccacgaagac
1321 atggacgcag ccaaggtgta cacgggtgag atgggccgtc tgaagagcta cgagaaccag
1381 aaaccgtgag tggaggaagc ggggtgggac ggacagctct ggggcccttg agtacccaca
1441 gcccagggag atgtgtgatc ctctggagtc ctctgaatga gcacagtggg gtccccacac
1501 tttcatgccc tctatcagga agggtacaag ctgcccaagg gacaggtgct cttccccacg
1561 caggccttag gagccaagcc ctgccatatt aaacttgggc aaaaagtccc attctgtcct
1621 tagagtccac tgccattggg catgcagctc agctggcgag tgcttccata acccgtgagg
1681 ccccggggtc cgtccccagg accgcacaga ctgggcgtgg tacacacacc tttgagctca
1741 gcacactcgg ggaaggaagt ccagttctct tatcctcagc tgcatagcgg ggttcaaggc
1801 aagccgggga tgcacgaaaa gtccaaacca ttccgttcac tttgacccct ccatccctct
1861 gggtgctgcc cagattcacg ctggaaccct ccttagtcat cgtggtctcc tggggtcaag
1921 ccagccatcc tgctgggtca gactcctcca cttgtcactc ctagccacac tgtggtccct
1981 gaatgtgagt gtgaaaacca aatggcatgc agtggtctca ggacttggca gctccactcc
2041 gctcaagtcc cccataggca gagggtctca aattttatag gaaccaggcc tgtgtgtccc
2101 ttcgctttgc ccatcttact acattcatgg gcaaatcact ggcctcctct tttcccatca
2161 gccccttcga tgctaagaat ccattcctgg ctgctgtcac cgccaaccgg aagctgaacc
2221 aaggcactga gcggcatcta atgcacctgg agttggacat ctcagactcc aagatcaggt
2281 acctgccgcc tcccatctcc ctgtggtaag cctggccctg aggcatctgg tggcttcctc
2341 ctgagccttg cacttccttc ctctaggtat gaatctggag atcacgtggc tgtgtaccca
2401 gccaatgact cagccctggt caaccagatt ggggagatcc tgggagctga cctggatgtc
2461 atcatgtctc taaacaatct cgatggtaag ttccagaatt gagggccttg
//