GenBank-Updates@genbank.bio.net (12/08/90)
LOCUS VLVCG 9202 bp ss-RNA VRL 08-DEC-1990
DEFINITION Visna lentivirus, Icelandic strains LV1-1 and 1514, complete
proviral genome.
ACCESSION M10608
KEYWORDS complete genome; endonuclease; env gene; envelope glycoprotein;
gag gene; integrase; nucleoprotein; pol gene; polyprotein;
protease; protein Q; protein S; reverse transcriptase;
trans-activator; transmembrane protein.
SOURCE Visna lentivirus extrachromosomal proviral DNA.
ORGANISM Visna virus
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (bases 1 to 9202)
AUTHORS Sonigo,P., Alizon,M., Staskus,K., Klatzmann,D., Cole,S., Danos,O.,
Retzel,E., Tiollais,P., Haase,A. and Wain-Hobson,S.
TITLE Nucleotide sequence of the Visna lentivirus: Relationship to the
AIDS virus
JOURNAL Cell 42, 369-382 (1985)
STANDARD full staff_review
FEATURES from to/span description
pept < 339 1817 gag protein (AA at 339)
pept < 1691 5008 pol protein (AA at 1691)
pept < 4956 5657 Q protein (AA at 4956)
pept < 5935 > 8160 env protein (AA at 5935)
pept < 8164 8907 env protein (AA at 8164)
site 8161 8163 internal stop codon in env in [Cell 42,
369-382 (1985)]
mRNA 1 9202 Visna genomic mRNA
LTR < 1 160 5' LTR
LTR 8852 > 9202 3' LTR
rpt 1 97 R repeat 5' copy
rpt 9106 9202 R repeat 3' copy
binding 161 177 primer (Lys-tRNA) binding site
signal 9178 9183 poly-A signal
virion 1 9202 visna lentivirus virion
BASE COUNT 3416 a 1419 c 2399 g 1968 t
ORIGIN 5' end of virion; 27 bp upstream of SstI site.
1 gggaaaagca gagtgctttg gagagctcga aggaaagagt ctccgggcct ctcctgcctg
61 cctgaaaagc tcaataaagg agttggctga tatctgagct tgctggttat tatcgggatt
121 cgttactaat tccgtgcaac accggagcgg atctcgcagc tggcgcccaa cgtggggctc
181 gacaaagaat cagaagaaaa atgagagtta tgggaccacg gacgctgctc ctgtgaggac
241 ggcgaggaga gtaacggaca cggacaaaaa gtgaaagaaa gcttcgggga cgcctgaagt
301 aaggtaagag agacacctac tggggaagta gggaatagcc cttcagtgaa ggagaaagtg
361 ttgcttgggc acaggaggag ggttcgcgac cccttagaaa gacggagggg cgcgggcgtc
421 ctcctgggcc gaggggacac aagagcaaca ctggtaagga agccgccgtg gtgaggctag
481 ctagagacat ggcgaagcaa ggctcaaagg agaaaaaggg ataccccgag ctcaaggaag
541 taattaaagc aacttgtaaa ataagggtag ggcccgggaa ggagaccttg acagaaggga
601 attgtctatg ggcattaaaa actatagact ttatatttga ggatttaaaa acagagccgt
661 ggacgattac aaaaatgtat acagtatggg atagattaaa agggctaact ccggaggaaa
721 caagcaaaag agaattcgcc tccttgcaag ctacgttggc ttgcataatg tgtagtcaaa
781 tgggcatgaa gcccgagaca gtgcaggcag caaagggaat aataagtatg aaagaaggac
841 tacacgaaaa taaggaggcc aagggggaga aggtagagca actctacccc aacttagaga
901 aacataggga agtttatcct attgtgaatt tgcaagcagg agggagaagt tggaaggcgg
961 tagagtcagt agtcttccag caactgcaaa cagtggcaat gcagcatgga cttgtgtccg
1021 aggattttga gaggcaattg gcatattatg ctactacctg gactagtaaa gatatattag
1081 aagtattggc tatgatgcct gggaatagag cacagaagga attaatacaa ggaaaattaa
1141 atgaagaagc agaaaggtgg gtaagacaaa atccacccgg gccgaatgtc ctcacggtgg
1201 atcaaataat gggagtggga caaaccaatc agcaggcatc tcaagccaat atggatcagg
1261 caagacagat atgcctgcag tgggtaataa cagcgttaag atcagtgagg catatgtcac
1321 atagaccagg aaaccctatg ttagtgaagc agaagaatac tgagagttat gaagacttca
1381 tagctcgcct actagaggct attgatgcgg aaccagtgac ggaccctata aaaacatatt
1441 taaaagtaac attgtcatat acaaatgcta gcacagactg tcaaaagcag atggatagga
1501 cattggggac gagggttcaa caagcaacgg tagaagaaaa gatgcaagca tgtcgagatg
1561 tgggatccga aggatttaag atgcaattat tagcacaagc tttgagaccg caagggaagg
1621 caggacacaa aggggtaaat caaaagtgtt ataattgtgg aaaaccagga catctcgcaa
1681 gacagtgtag acaaggaata atatgccatc attgtggaaa aagaggacat atgcaaaagg
1741 actgccggca gaagaaacag cagggaaaca acaggagggg gccacgtgtg gtgccgtccg
1801 cgccccctat gttgtaacag aagcaccacc caaaatagaa ataaaagtag gaacaaggtg
1861 gaaaaaatta ttagtagata cgggggcaga taaaactata gtaacatccc atgatatgtc
1921 agggatacca aagggaagga taatattaca gggcataggg ggaataatag aaggagaaaa
1981 atgggaacaa gtacacttgc aatataaaga taaaatgatc aaaggtacca tagtggtgtt
2041 agctacgagt ccggtagaag tattaggaag agataatatg agagaattgg gaataggatt
2101 aattatggca aatttagaag aaaagaaaat tcccagtaca agagtaagat taaaagaggg
2161 atgtaaggga ccccacatag cgcaatggcc tttgacgcaa gaaaaattag agggattaaa
2221 agaaatagta gacagattag agaaggaagg gaaagtagga agagcgcccc cacactggac
2281 ttgtaatacc cctatatttt gtattaagaa gaaatcagga aaatggagga tgttaataga
2341 ttttagagaa ttaaataagc aaacagaaga tttagcagaa gcacagttag ggttacctca
2401 tccaggagga ttacagagaa agaaacatgt aacaatatta gatataggag atgcatattt
2461 tacaatacca ttatatgagc catatagaca atatacatgc tttaccatgt taagtccaaa
2521 taatttagga ccatgtgtaa gatattattg gaaagtgtta ccacaaggat ggaaattaag
2581 tcctgcagtg tatcaattta caatgcaaaa aatattaaga ggatggatag aagaacaccc
2641 tatgatacaa tttggaatat acatggatga tatctatata gggagtgatt taggactaga
2701 agagcacagg ggtatcgtga acgaactagc atcatatata gcgcaatatg gattcatgct
2761 gcctgaagat aagaggcaag aaggataccc ggcgaaatgg cttggatttg aattgcatcc
2821 ggagaaatgg aaatttcaaa aacatacgct cccagagatt acagaaggac ccataacctt
2881 gaataaacta cagaaattag taggagattt agtttggaga caatccctaa taggaaaaag
2941 catcccaaat atcttaaaat taatggaagg agatagggct ttacaaagtg aaagatacat
3001 agagagtata catgtaagag aatgggaagc ctgtagacaa aagctgaagg aaatggaagg
3061 aaattattat gatgaagaga aggatatcta tgggcaacta gattggggaa ataaagcaat
3121 agaatacata gtatttcaag aaaaaggaaa acctttatgg gtaaatgtag tacatagtat
3181 taagaatttg agtcaagccc aacaaattat caaagcagca caaaaactga cacaagaagt
3241 aataataaga acaggcaaga taccctggat tttgttgccg ggaagggaag aagattggat
3301 attagagtta caaatgggaa acataaattg gatgccatca ttttggtcat gttataaagg
3361 ctcggtgagg tggaaaaaga ggaatgtaat agcggaacta gtcccaggac caacatatta
3421 taccgatgga ggaaagaaaa atgggcgggg aagcctgggg tatattgcct ccacaggtga
3481 aaagtttaga atacatgaag aagggacaaa tcagcagtta gaattgaggg ccatagaaga
3541 ggcatgtaaa cagggaccag aaaaaatgaa tatagtaaca gatagcaggt atgcatatga
3601 atttatgttg cggaactggg acgaagaagt aataagaaac cctatacaag cgagaattat
3661 ggaattagtg cataataaag aaaaaatagg ggtacattgg gtgcctggac acaaggggat
3721 tcctcaaaat gaagaaatag ataggtatat ctcagaaata tttttagcaa aagagggaag
3781 agggatttta caaaaaaggg cagaagatgc tggatatgac ttaatatgtc cacaggagat
3841 aagcattccg gcgggacaag tgaaaaggat agcaattgac ttgaaaataa atttgaaaaa
3901 ggaccagtgg gccatgatag ggaccaaaag cagttttgca aataagggag tattcgtaca
3961 aggaggtatc atagattcgg gatatcaagg aacaatacaa gtagtaatat ataatagtaa
4021 taataaagaa gtagtaatac cacagggaag aaaatttgca cagttgatcc tcatgcctct
4081 aatacatgaa gagttggagc catggggaga aacaagaaaa acagaaagag gggaacaagg
4141 atttggatca acagggatgt attggataga aaatattccc ctagcagaag aagagcataa
4201 caaatggcat caagatgctg tgtccttgca tttagaattt gggattccca ggacagctgc
4261 agaagatata gttcaacaat gtgatgtgtg tcaagaaaat aaaatgccta gtacattaag
4321 aggcagtaat aaaaggggca tagaccattg gcaagtagac tatacccact atgaagacaa
4381 gataatattg gtctgggtag aaacaaattc aggactaatc tatgcagaga gggtaaaagg
4441 agaaacagga caagaattta gggtgcaaac tatgaaatgg tatgcgatgt ttgccccgaa
4501 atcattgcag tctgataacg gaccagcatt tgtagcagaa tctactcagc tcttaatgaa
4561 atatttgggc atagaacata ctacagggat cccctggaac ccacaatctc aagcattagt
4621 agagagaaca catcagacgt taaagaatac attagaaaaa cttataccta tgtttaatgc
4681 gtttgaatca gccctcgcag ggaccctcat tactctaaat ataaaaagaa agggtgggct
4741 agggacaagc cctatggata tatttatatt taataaggaa caacaaagaa tacagcaaca
4801 aagtaaatca aaacaagaaa aaattcgatt ttgttattac agaacaagaa aaagagggca
4861 tccaggagag tggcaaggac caacacaggt actttggggc ggggacggtg cgattgtagt
4921 gaaagacaga ggcacagata gatatctggt gatagctaac aaagatgtta agttcatacc
4981 gccaccaaaa gaaatacaaa aagaataaag caagggagat aggaccccag ttgccactat
5041 gggcatggaa agaaacagca tttagtataa atcaagaacc ctattggtat agtaccataa
5101 ggctacaagg gttgatgtgg aataaaagag ggcataaact tatgtttgta aaagaaaacc
5161 aagggtatga gtattgggaa acatcaggaa aacagtggaa aatggagata agacgagatc
5221 tggatctgat agcccaaata aattttagaa atgcatggca atataaaagc cagggagaat
5281 ggaaaacaat aggggtctgg tatgaatcac caggggatta caagggaaaa gagaatcagt
5341 tttggttcca ttggagaata gctctctgca gctgtaacaa aacaaggtgg gatatacggg
5401 aattcatgat agggaagcat aggtgggatt tatgtaaatc gtgtatacaa ggggagatag
5461 ttaagaatac aaatccaaga agcttacaac gcttagcttt attgcaccta gcaaaagacc
5521 atgtatttca agtaatgcca ttgtggagag ccaggagagt cacagtgcag aagtttccat
5581 ggtgtcgtag cccaatgggt tacacgatac cttggtctct gcaggaatgc tgggaaatgg
5641 aatccatctt tgaataatgg aagaagtacc aagaagacag ccaggaggct tagtagaagt
5701 agagggagta tttcaatttt atgaagactg ggaatgttgg gactatgtaa gtcaaagagt
5761 atctgacgaa agactacaac gatggctagc tatgcttact aataatcagc ttagaagaca
5821 agtaattagg gaagcacaga tctggatgtg gaaacataag ggagctgcag ttagaagaaa
5881 ttgtggttgc aggctatgta accccggctg gggaagccaa gtaagaaatg ttgaactgtg
5941 ataagcctgt ctaggatggc cagcaaagaa agtaagccaa gcagaacaac gtggagagac
6001 atggagcccc cactccgaga aacatggaat caagtattac aggagctagt aaaaagacaa
6061 caacaggagg aagaagaaca gcagggactg gtatcaggta agaaaaaatc atgggtaagt
6121 attgacctcc tggggacaga aggaaaagat attaagaagg taaatatatg ggaaccatgt
6181 gaaaagtggt ttgcacaggt ggtatggggg gtattgtggg tgctgcaaat tgtgttgtgg
6241 ggatgtctca tgtgggaagt gagaaaagga aaccagtgtc aagcagaaga agtgatagca
6301 ttggtgagtg atcctggagg atttcagagg gtgcagcacg tagaaacagt gcctgtgacc
6361 tgtgtgacaa aaaatttcac tcaatgggga tgtcaacccg agggggccta tccagatcct
6421 gaactggagt atagaaatat atctagggaa atcttagagg aagtatataa acaagactgg
6481 ccctggaata cttatcattg gcctttatgg caaatggaaa atatgaggca atggatgaaa
6541 gaaaatgaaa aggagtataa ggaaagaaca aacaaaacga aggaagatat agatgatctg
6601 gtagcaggaa gaataagggg aagattttgt gtgccatatc cctatgcttt actacgatgt
6661 gaggagtggt gttggtaccc tgaatctatt aatcaagaaa caggacatgc tgaaaaaata
6721 aaaataaact gcacaaaagc aaaagcagtt tcttgtacag aaaaaatgcc cttagcagca
6781 gtccagcggg tatattggga aaaagaggat gaagaaagca tgaagttttt gaatataaaa
6841 gcctgtaata tatcattgag gtgtcaagat gaaggaaaga gtccgggagg atgtgtacaa
6901 ggatacccca ttccaaaggg agcagaaata ataccagaag ctatgaaata cctcagggga
6961 aagaaaagtc gatatggagg gatcaaggat aaaaatgggg aattaaaatt acctctctct
7021 gtaagggtat gggtgaggat ggcgaatttg tcaggatggg tgaatggaac gcctccttac
7081 tggagtgcaa ggattaatgg gagtacaggg ataaatggaa caaggtggta tggagtagga
7141 acactacatc acttagggta taacattagc agtaacccag agggagggat atgtaacttt
7201 acaggagaac tttggatagg gggtgacaga ttcccatatt attataagcc ctcatggaat
7261 tgttcacaaa attggacagg tcacccagta tggcacgtat ttagatactt ggatatgaca
7321 gaacatatga caagcagatg tatacaaaga cctaaaagac ataatataac agtaggaaat
7381 ggaacaataa cggggaattg tagtgtaaca aattgggatg gatgtaactg tacaaggtca
7441 ggaaatcatt tgtataatag cacaagcgga ggactgttag taatcatatg caggcaaaat
7501 agcaccataa caggaataat gggaacgaac actaattgga caacaatgtg gaacatctac
7561 caaaattgct caagatgtaa caacagtagc ctagacagaa caggtagtgg gaccttggga
7621 acagtgaaca accttaaatg tagcttacca cacagaaatg agagtaacaa gtggacatgt
7681 aagagccaaa gagactcata tatagctgga agagacttct ggggaaaagt aaaagcaaaa
7741 tacagttgtg agagtaattt agggggtcta gatagtatga tgcatcagca aatgttactg
7801 caacgatacc aagtaataag agtaagagct tacacatatg gtgttgtaga aatgccacaa
7861 tcgtatatgg aggagcgagg ggaaaacagg aggtcaagaa ggaacctcca aaggaagaaa
7921 agagggatag gcttggttat tgtgctagcc atcatggcaa taatcgctgc tgcaggagct
7981 ggtctcggtg tcgcaaacgc cgtgcagcaa tcctatacca ggacggctgt ccagtctctt
8041 gctaacgcaa ctgctgccca gcaggaagtg ttggaagcat cgtatgccat ggtacagcat
8101 atagccaaag gaataagaat cctagaggca agagtggcta gggtggaagc cctggtagat
8161 tgaatgatgg tataccaaga attggattgc tggcattatc aacactactg tgtaacctca
8221 acaagaagtg aagtagccaa ttatgtaaac tggacaagat ttaaagataa ctgtacctgg
8281 caacagtggg aggaagaaat agaacaacac gagggaaact tgagtctatt actcagagaa
8341 gcagcattac aagtacacat agctcaaaga gatgctagga gaatcccaga tgcttggaaa
8401 gcaatacaag aagcatttaa ctggtcctct tggttctcgt ggctcaaata tataccctgg
8461 attatcatgg gaattgtagg attaatgtgt tttagaatac taatgtgtgt gatatcaatg
8521 tgtttgcagg cttacaagca agtaaagcag atcagatata cacaggtaac agtggtgata
8581 gaagcaccgg tggaattgga ggaaaaacaa aaaagaaacg gggatggtac aaatggctgc
8641 gcaagcttag agcacgagag aagaacatcc catcgcagtt ttatccagat atggagagca
8701 acatggtggg catggaaaac ctcaccttgg agacacaact ggaggacaat gccctatata
8761 accctgctac ccatattggt gatatggcaa tggatggaag agaatggatg gaatggagag
8821 aatcagcaca aaaagaaaaa agaaagggtg gactgtcagg acagagaaca aatgcctacc
8881 ctggaaaatg actatgtaga gttataggaa ggtcatgtca ctgttaccag aaatcatagt
8941 caggatgaca cagcaaatgt aaccagttac cagaaatcat agtcaggatg acacagcaaa
9001 tgtaaccgca agttctgctt ttttgcgcta agtcatgtag cagctgatgc ttgagtcata
9061 accgcagatg taaacaagtt gcctatataa gccgcttgct agctggggaa aagcagagtg
9121 ctttggagag ctcgaaggaa agagtctccg ggcctctcct gcctgcctga aaagctcaat
9181 aaaggagttg gctgatatct ga
//GenBank-Updates@genbank.bio.net (12/08/90)
LOCUS VLVCGA 9202 bp ss-RNA VRL 08-DEC-1990
DEFINITION Visna lentivirus, Icelandic strains LV1-1 and 1514, complete
proviral genome.
ACCESSION M51543
KEYWORDS complete genome; endonuclease; env gene; envelope glycoprotein;
gag gene; integrase; nucleoprotein; pol gene; polyprotein;
protease; reverse transcriptase; sor gene; trans-activator;
transmembrane protein.
SOURCE Visna lentivirus extrachromosomal proviral DNA.
ORGANISM Visna virus
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (bases 1 to 9202)
AUTHORS Braun,M.J., Clements,J.E. and Gonda,M.A.
TITLE The visna virus genome: Evidence for a hypervariable site in the
env gene and sequence homology among lentivirus envelope proteins
JOURNAL J. Virol. 61, 4046-4054 (1987)
STANDARD full staff_review
FEATURES from to/span description
pept < 339 1817 gag protein (AA at 339)
pept < 1691 5008 pol protein (AA at 1691)
pept < 4956 5657 sor protein (AA at 4956)
pept < 5654 5941 tat protein (AA at 5654)
pept < 5935 > 8160 env protein (AA at 5935)
pept < 8164 8907 env protein (AA at 8164) /pseudo="8161-8163"
site 8161 8163 internal stop codon in env protein
mRNA 1 9202 Visna genomic mRNA
LTR 1 160 5' LTR
LTR 8852 9202 3' LTR
rpt 1 97 R repeat 5' copy
rpt 9106 9202 R repeat 3' copy
binding 161 177 primer (Lys-tRNA) binding site
signal 9178 9183 poly-A signal
virion 1 9202 visna lentivirus virion
BASE COUNT 3416 a 1419 c 2399 g 1968 t
ORIGIN 5' end of virion; 27 bp upstream of SstI site.
1 gggaaaagca gagtgctttg gagagctcga aggaaagagt ctccgggcct ctcctgcctg
61 cctgaaaagc tcaataaagg agttggctga tatctgagct tgctggttat tatcgggatt
121 cgttactaat tccgtgcaac accggagcgg atctcgcagc tggcgcccaa cgtggggctc
181 gacaaagaat cagaagaaaa atgagagtta tgggaccacg gacgctgctc ctgtgaggac
241 ggcgaggaga gtaacggaca cggacaaaaa gtgaaagaaa gcttcgggga cgcctgaagt
301 aaggtaagag agacacctac tggggaagta gggaatagcc cttcagtgaa ggagaaagtg
361 ttgcttgggc acaggaggag ggttcgcgac cccttagaaa gacggagggg cgcgggcgtc
421 ctcctgggcc gaggggacac aagagcaaca ctggtaagga agccgccgtg gtgaggctag
481 ctagagacat ggcgaagcaa ggctcaaagg agaaaaaggg ataccccgag ctcaaggaag
541 taattaaagc aacttgtaaa ataagggtag ggcccgggaa ggagaccttg acagaaggga
601 attgtctatg ggcattaaaa actatagact ttatatttga ggatttaaaa acagagccgt
661 ggacgattac aaaaatgtat acagtatggg atagattaaa agggctaact ccggaggaaa
721 caagcaaaag agaattcgcc tccttgcaag ctacgttggc ttgcataatg tgtagtcaaa
781 tgggcatgaa gcccgagaca gtgcaggcag caaagggaat aataagtatg aaagaaggac
841 tacacgaaaa taaggaggcc aagggggaga aggtagagca actctacccc aacttagaga
901 aacataggga agtttatcct attgtgaatt tgcaagcagg agggagaagt tggaaggcgg
961 tagagtcagt agtcttccag caactgcaaa cagtggcaat gcagcatgga cttgtgtccg
1021 aggattttga gaggcaattg gcatattatg ctactacctg gactagtaaa gatatattag
1081 aagtattggc tatgatgcct gggaatagag cacagaagga attaatacaa ggaaaattaa
1141 atgaagaagc agaaaggtgg gtaagacaaa atccacccgg gccgaatgtc ctcacggtgg
1201 atcaaataat gggagtggga caaaccaatc agcaggcatc tcaagccaat atggatcagg
1261 caagacagat atgcctgcag tgggtaataa cagcgttaag atcagtgagg catatgtcac
1321 atagaccagg aaaccctatg ttagtgaagc agaagaatac tgagagttat gaagacttca
1381 tagctcgcct actagaggct attgatgcgg aaccagtgac ggaccctata aaaacatatt
1441 taaaagtaac attgtcatat acaaatgcta gcacagactg tcaaaagcag atggatagga
1501 cattggggac gagggttcaa caagcaacgg tagaagaaaa gatgcaagca tgtcgagatg
1561 tgggatccga aggatttaag atgcaattat tagcacaagc tttgagaccg caagggaagg
1621 caggacacaa aggggtaaat caaaagtgtt ataattgtgg aaaaccagga catctcgcaa
1681 gacagtgtag acaaggaata atatgccatc attgtggaaa aagaggacat atgcaaaagg
1741 actgccggca gaagaaacag cagggaaaca acaggagggg gccacgtgtg gtgccgtccg
1801 cgccccctat gttgtaacag aagcaccacc caaaatagaa ataaaagtag gaacaaggtg
1861 gaaaaaatta ttagtagata cgggggcaga taaaactata gtaacatccc atgatatgtc
1921 agggatacca aagggaagga taatattaca gggcataggg ggaataatag aaggagaaaa
1981 atgggaacaa gtacacttgc aatataaaga taaaatgatc aaaggtacca tagtggtgtt
2041 agctacgagt ccggtagaag tattaggaag agataatatg agagaattgg gaataggatt
2101 aattatggca aatttagaag aaaagaaaat tcccagtaca agagtaagat taaaagaggg
2161 atgtaaggga ccccacatag cgcaatggcc tttgacgcaa gaaaaattag agggattaaa
2221 agaaatagta gacagattag agaaggaagg gaaagtagga agagcgcccc cacactggac
2281 ttgtaatacc cctatatttt gtattaagaa gaaatcagga aaatggagga tgttaataga
2341 ttttagagaa ttaaataagc aaacagaaga tttagcagaa gcacagttag ggttacctca
2401 tccaggagga ttacagagaa agaaacatgt aacaatatta gatataggag atgcatattt
2461 tacaatacca ttatatgagc catatagaca atatacatgc tttaccatgt taagtccaaa
2521 taatttagga ccatgtgtaa gatattattg gaaagtgtta ccacaaggat ggaaattaag
2581 tcctgcagtg tatcaattta caatgcaaaa aatattaaga ggatggatag aagaacaccc
2641 tatgatacaa tttggaatat acatggatga tatctatata gggagtgatt taggactaga
2701 agagcacagg ggtatcgtga acgaactagc atcatatata gcgcaatatg gattcatgct
2761 gcctgaagat aagaggcaag aaggataccc ggcgaaatgg cttggatttg aattgcatcc
2821 ggagaaatgg aaatttcaaa aacatacgct cccagagatt acagaaggac ccataacctt
2881 gaataaacta cagaaattag taggagattt agtttggaga caatccctaa taggaaaaag
2941 catcccaaat atcttaaaat taatggaagg agatagggct ttacaaagtg aaagatacat
3001 agagagtata catgtaagag aatgggaagc ctgtagacaa aagctgaagg aaatggaagg
3061 aaattattat gatgaagaga aggatatcta tgggcaacta gattggggaa ataaagcaat
3121 agaatacata gtatttcaag aaaaaggaaa acctttatgg gtaaatgtag tacatagtat
3181 taagaatttg agtcaagccc aacaaattat caaagcagca caaaaactga cacaagaagt
3241 aataataaga acaggcaaga taccctggat tttgttgccg ggaagggaag aagattggat
3301 attagagtta caaatgggaa acataaattg gatgccatca ttttggtcat gttataaagg
3361 ctcggtgagg tggaaaaaga ggaatgtaat agcggaacta gtcccaggac caacatatta
3421 taccgatgga ggaaagaaaa atgggcgggg aagcctgggg tatattgcct ccacaggtga
3481 aaagtttaga atacatgaag aagggacaaa tcagcagtta gaattgaggg ccatagaaga
3541 ggcatgtaaa cagggaccag aaaaaatgaa tatagtaaca gatagcaggt atgcatatga
3601 atttatgttg cggaactggg acgaagaagt aataagaaac cctatacaag cgagaattat
3661 ggaattagtg cataataaag aaaaaatagg ggtacattgg gtgcctggac acaaggggat
3721 tcctcaaaat gaagaaatag ataggtatat ctcagaaata tttttagcaa aagagggaag
3781 agggatttta caaaaaaggg cagaagatgc tggatatgac ttaatatgtc cacaggagat
3841 aagcattccg gcgggacaag tgaaaaggat agcaattgac ttgaaaataa atttgaaaaa
3901 ggaccagtgg gccatgatag ggaccaaaag cagttttgca aataagggag tattcgtaca
3961 aggaggtatc atagattcgg gatatcaagg aacaatacaa gtagtaatat ataatagtaa
4021 taataaagaa gtagtaatac cacagggaag aaaatttgca cagttgatcc tcatgcctct
4081 aatacatgaa gagttggagc catggggaga aacaagaaaa acagaaagag gggaacaagg
4141 atttggatca acagggatgt attggataga aaatattccc ctagcagaag aagagcataa
4201 caaatggcat caagatgctg tgtccttgca tttagaattt gggattccca ggacagctgc
4261 agaagatata gttcaacaat gtgatgtgtg tcaagaaaat aaaatgccta gtacattaag
4321 aggcagtaat aaaaggggca tagaccattg gcaagtagac tatacccact atgaagacaa
4381 gataatattg gtctgggtag aaacaaattc aggactaatc tatgcagaga gggtaaaagg
4441 agaaacagga caagaattta gggtgcaaac tatgaaatgg tatgcgatgt ttgccccgaa
4501 atcattgcag tctgataacg gaccagcatt tgtagcagaa tctactcagc tcttaatgaa
4561 atatttgggc atagaacata ctacagggat cccctggaac ccacaatctc aagcattagt
4621 agagagaaca catcagacgt taaagaatac attagaaaaa cttataccta tgtttaatgc
4681 gtttgaatca gccctcgcag ggaccctcat tactctaaat ataaaaagaa agggtgggct
4741 agggacaagc cctatggata tatttatatt taataaggaa caacaaagaa tacagcaaca
4801 aagtaaatca aaacaagaaa aaattcgatt ttgttattac agaacaagaa aaagagggca
4861 tccaggagag tggcaaggac caacacaggt actttggggc ggggacggtg cgattgtagt
4921 gaaagacaga ggcacagata gatatctggt gatagctaac aaagatgtta agttcatacc
4981 gccaccaaaa gaaatacaaa aagaataaag caagggagat aggaccccag ttgccactat
5041 gggcatggaa agaaacagca tttagtataa atcaagaacc ctattggtat agtaccataa
5101 ggctacaagg gttgatgtgg aataaaagag ggcataaact tatgtttgta aaagaaaacc
5161 aagggtatga gtattgggaa acatcaggaa aacagtggaa aatggagata agacgagatc
5221 tggatctgat agcccaaata aattttagaa atgcatggca atataaaagc cagggagaat
5281 ggaaaacaat aggggtctgg tatgaatcac caggggatta caagggaaaa gagaatcagt
5341 tttggttcca ttggagaata gctctctgca gctgtaacaa aacaaggtgg gatatacggg
5401 aattcatgat agggaagcat aggtgggatt tatgtaaatc gtgtatacaa ggggagatag
5461 ttaagaatac aaatccaaga agcttacaac gcttagcttt attgcaccta gcaaaagacc
5521 atgtatttca agtaatgcca ttgtggagag ccaggagagt cacagtgcag aagtttccat
5581 ggtgtcgtag cccaatgggt tacacgatac cttggtctct gcaggaatgc tgggaaatgg
5641 aatccatctt tgaataatgg aagaagtacc aagaagacag ccaggaggct tagtagaagt
5701 agagggagta tttcaatttt atgaagactg ggaatgttgg gactatgtaa gtcaaagagt
5761 atctgacgaa agactacaac gatggctagc tatgcttact aataatcagc ttagaagaca
5821 agtaattagg gaagcacaga tctggatgtg gaaacataag ggagctgcag ttagaagaaa
5881 ttgtggttgc aggctatgta accccggctg gggaagccaa gtaagaaatg ttgaactgtg
5941 ataagcctgt ctaggatggc cagcaaagaa agtaagccaa gcagaacaac gtggagagac
6001 atggagcccc cactccgaga aacatggaat caagtattac aggagctagt aaaaagacaa
6061 caacaggagg aagaagaaca gcagggactg gtatcaggta agaaaaaatc atgggtaagt
6121 attgacctcc tggggacaga aggaaaagat attaagaagg taaatatatg ggaaccatgt
6181 gaaaagtggt ttgcacaggt ggtatggggg gtattgtggg tgctgcaaat tgtgttgtgg
6241 ggatgtctca tgtgggaagt gagaaaagga aaccagtgtc aagcagaaga agtgatagca
6301 ttggtgagtg atcctggagg atttcagagg gtgcagcacg tagaaacagt gcctgtgacc
6361 tgtgtgacaa aaaatttcac tcaatgggga tgtcaacccg agggggccta tccagatcct
6421 gaactggagt atagaaatat atctagggaa atcttagagg aagtatataa acaagactgg
6481 ccctggaata cttatcattg gcctttatgg caaatggaaa atatgaggca atggatgaaa
6541 gaaaatgaaa aggagtataa ggaaagaaca aacaaaacga aggaagatat agatgatctg
6601 gtagcaggaa gaataagggg aagattttgt gtgccatatc cctatgcttt actacgatgt
6661 gaggagtggt gttggtaccc tgaatctatt aatcaagaaa caggacatgc tgaaaaaata
6721 aaaataaact gcacaaaagc aaaagcagtt tcttgtacag aaaaaatgcc cttagcagca
6781 gtccagcggg tatattggga aaaagaggat gaagaaagca tgaagttttt gaatataaaa
6841 gcctgtaata tatcattgag gtgtcaagat gaaggaaaga gtccgggagg atgtgtacaa
6901 ggatacccca ttccaaaggg agcagaaata ataccagaag ctatgaaata cctcagggga
6961 aagaaaagtc gatatggagg gatcaaggat aaaaatgggg aattaaaatt acctctctct
7021 gtaagggtat gggtgaggat ggcgaatttg tcaggatggg tgaatggaac gcctccttac
7081 tggagtgcaa ggattaatgg gagtacaggg ataaatggaa caaggtggta tggagtagga
7141 acactacatc acttagggta taacattagc agtaacccag agggagggat atgtaacttt
7201 acaggagaac tttggatagg gggtgacaga ttcccatatt attataagcc ctcatggaat
7261 tgttcacaaa attggacagg tcacccagta tggcacgtat ttagatactt ggatatgaca
7321 gaacatatga caagcagatg tatacaaaga cctaaaagac ataatataac agtaggaaat
7381 ggaacaataa cggggaattg tagtgtaaca aattgggatg gatgtaactg tacaaggtca
7441 ggaaatcatt tgtataatag cacaagcgga ggactgttag taatcatatg caggcaaaat
7501 agcaccataa caggaataat gggaacgaac actaattgga caacaatgtg gaacatctac
7561 caaaattgct caagatgtaa caacagtagc ctagacagaa caggtagtgg gaccttggga
7621 acagtgaaca accttaaatg tagcttacca cacagaaatg agagtaacaa gtggacatgt
7681 aagagccaaa gagactcata tatagctgga agagacttct ggggaaaagt aaaagcaaaa
7741 tacagttgtg agagtaattt agggggtcta gatagtatga tgcatcagca aatgttactg
7801 caacgatacc aagtaataag agtaagagct tacacatatg gtgttgtaga aatgccacaa
7861 tcgtatatgg aggagcgagg ggaaaacagg aggtcaagaa ggaacctcca aaggaagaaa
7921 agagggatag gcttggttat tgtgctagcc atcatggcaa taatcgctgc tgcaggagct
7981 ggtctcggtg tcgcaaacgc cgtgcagcaa tcctatacca ggacggctgt ccagtctctt
8041 gctaacgcaa ctgctgccca gcaggaagtg ttggaagcat cgtatgccat ggtacagcat
8101 atagccaaag gaataagaat cctagaggca agagtggcta gggtggaagc cctggtagat
8161 tgaatgatgg tataccaaga attggattgc tggcattatc aacactactg tgtaacctca
8221 acaagaagtg aagtagccaa ttatgtaaac tggacaagat ttaaagataa ctgtacctgg
8281 caacagtggg aggaagaaat agaacaacac gagggaaact tgagtctatt actcagagaa
8341 gcagcattac aagtacacat agctcaaaga gatgctagga gaatcccaga tgcttggaaa
8401 gcaatacaag aagcatttaa ctggtcctct tggttctcgt ggctcaaata tataccctgg
8461 attatcatgg gaattgtagg attaatgtgt tttagaatac taatgtgtgt gatatcaatg
8521 tgtttgcagg cttacaagca agtaaagcag atcagatata cacaggtaac agtggtgata
8581 gaagcaccgg tggaattgga ggaaaaacaa aaaagaaacg gggatggtac aaatggctgc
8641 gcaagcttag agcacgagag aagaacatcc catcgcagtt ttatccagat atggagagca
8701 acatggtggg catggaaaac ctcaccttgg agacacaact ggaggacaat gccctatata
8761 accctgctac ccatattggt gatatggcaa tggatggaag agaatggatg gaatggagag
8821 aatcagcaca aaaagaaaaa agaaagggtg gactgtcagg acagagaaca aatgcctacc
8881 ctggaaaatg actatgtaga gttataggaa ggtcatgtca ctgttaccag aaatcatagt
8941 caggatgaca cagcaaatgt aaccagttac cagaaatcat agtcaggatg acacagcaaa
9001 tgtaaccgca agttctgctt ttttgcgcta agtcatgtag cagctgatgc ttgagtcata
9061 accgcagatg taaacaagtt gcctatataa gccgcttgct agctggggaa aagcagagtg
9121 ctttggagag ctcgaaggaa agagtctccg ggcctctcct gcctgcctga aaagctcaat
9181 aaaggagttg gctgatatct ga
//GenBank-Updates@genbank.bio.net (01/31/91)
LOCUS VLVCG 9202 bp ss-RNA VRL 31-JAN-1991
DEFINITION Visna lentivirus, Icelandic strains LV1-1 and 1514, complete
proviral genome.
ACCESSION M10608
KEYWORDS complete genome; endonuclease; env gene; envelope glycoprotein;
gag gene; integrase; nucleoprotein; pol gene; polyprotein;
protease; protein Q; protein S; reverse transcriptase;
trans-activator; transmembrane protein.
SOURCE Visna lentivirus extrachromosomal proviral DNA.
ORGANISM Visna virus
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (bases 1 to 9202)
AUTHORS Sonigo,P., Alizon,M., Staskus,K., Klatzmann,D., Cole,S., Danos,O.,
Retzel,E., Tiollais,P., Haase,A. and Wain-Hobson,S.
TITLE Nucleotide sequence of the Visna lentivirus: Relationship to the
AIDS virus
JOURNAL Cell 42, 369-382 (1985)
STANDARD full staff_review
FEATURES Location/Qualifiers
LTR <1..160
/note="5' LTR"
mRNA 1..9202
/note="Visna genomic mRNA"
repeat_region 1..97
/note="R repeat 5' copy"
virion 1..9202
/note="visna lentivirus virion"
misc_binding 161..177
/note="primer (Lys-tRNA) binding site"
CDS 339..1817
/product="gag protein"
/gene="gag"
/codon_start=339
/partial
CDS 1691..5008
/product="pol protein"
/gene="pol"
/codon_start=1691
/partial
CDS 4956..5657
/product="Q protein"
/codon_start=4956
/partial
CDS 5935..8907
/pseudo=8161-8163
/product="envelope protein"
/gene="env"
/codon_start=5935
/partial
misc_feature 8161..8163
/note="internal stop codon in env in [Cell 42, 369-382
(1985)]"
LTR 8852..>9202
/note="3' LTR"
repeat_region 9106..9202
/note="R repeat 3' copy"
misc_signal 9178..9183
BASE COUNT 3416 a 1419 c 2399 g 1968 t
ORIGIN 5' end of virion; 27 bp upstream of SstI site.
1 gggaaaagca gagtgctttg gagagctcga aggaaagagt ctccgggcct ctcctgcctg
61 cctgaaaagc tcaataaagg agttggctga tatctgagct tgctggttat tatcgggatt
121 cgttactaat tccgtgcaac accggagcgg atctcgcagc tggcgcccaa cgtggggctc
181 gacaaagaat cagaagaaaa atgagagtta tgggaccacg gacgctgctc ctgtgaggac
241 ggcgaggaga gtaacggaca cggacaaaaa gtgaaagaaa gcttcgggga cgcctgaagt
301 aaggtaagag agacacctac tggggaagta gggaatagcc cttcagtgaa ggagaaagtg
361 ttgcttgggc acaggaggag ggttcgcgac cccttagaaa gacggagggg cgcgggcgtc
421 ctcctgggcc gaggggacac aagagcaaca ctggtaagga agccgccgtg gtgaggctag
481 ctagagacat ggcgaagcaa ggctcaaagg agaaaaaggg ataccccgag ctcaaggaag
541 taattaaagc aacttgtaaa ataagggtag ggcccgggaa ggagaccttg acagaaggga
601 attgtctatg ggcattaaaa actatagact ttatatttga ggatttaaaa acagagccgt
661 ggacgattac aaaaatgtat acagtatggg atagattaaa agggctaact ccggaggaaa
721 caagcaaaag agaattcgcc tccttgcaag ctacgttggc ttgcataatg tgtagtcaaa
781 tgggcatgaa gcccgagaca gtgcaggcag caaagggaat aataagtatg aaagaaggac
841 tacacgaaaa taaggaggcc aagggggaga aggtagagca actctacccc aacttagaga
901 aacataggga agtttatcct attgtgaatt tgcaagcagg agggagaagt tggaaggcgg
961 tagagtcagt agtcttccag caactgcaaa cagtggcaat gcagcatgga cttgtgtccg
1021 aggattttga gaggcaattg gcatattatg ctactacctg gactagtaaa gatatattag
1081 aagtattggc tatgatgcct gggaatagag cacagaagga attaatacaa ggaaaattaa
1141 atgaagaagc agaaaggtgg gtaagacaaa atccacccgg gccgaatgtc ctcacggtgg
1201 atcaaataat gggagtggga caaaccaatc agcaggcatc tcaagccaat atggatcagg
1261 caagacagat atgcctgcag tgggtaataa cagcgttaag atcagtgagg catatgtcac
1321 atagaccagg aaaccctatg ttagtgaagc agaagaatac tgagagttat gaagacttca
1381 tagctcgcct actagaggct attgatgcgg aaccagtgac ggaccctata aaaacatatt
1441 taaaagtaac attgtcatat acaaatgcta gcacagactg tcaaaagcag atggatagga
1501 cattggggac gagggttcaa caagcaacgg tagaagaaaa gatgcaagca tgtcgagatg
1561 tgggatccga aggatttaag atgcaattat tagcacaagc tttgagaccg caagggaagg
1621 caggacacaa aggggtaaat caaaagtgtt ataattgtgg aaaaccagga catctcgcaa
1681 gacagtgtag acaaggaata atatgccatc attgtggaaa aagaggacat atgcaaaagg
1741 actgccggca gaagaaacag cagggaaaca acaggagggg gccacgtgtg gtgccgtccg
1801 cgccccctat gttgtaacag aagcaccacc caaaatagaa ataaaagtag gaacaaggtg
1861 gaaaaaatta ttagtagata cgggggcaga taaaactata gtaacatccc atgatatgtc
1921 agggatacca aagggaagga taatattaca gggcataggg ggaataatag aaggagaaaa
1981 atgggaacaa gtacacttgc aatataaaga taaaatgatc aaaggtacca tagtggtgtt
2041 agctacgagt ccggtagaag tattaggaag agataatatg agagaattgg gaataggatt
2101 aattatggca aatttagaag aaaagaaaat tcccagtaca agagtaagat taaaagaggg
2161 atgtaaggga ccccacatag cgcaatggcc tttgacgcaa gaaaaattag agggattaaa
2221 agaaatagta gacagattag agaaggaagg gaaagtagga agagcgcccc cacactggac
2281 ttgtaatacc cctatatttt gtattaagaa gaaatcagga aaatggagga tgttaataga
2341 ttttagagaa ttaaataagc aaacagaaga tttagcagaa gcacagttag ggttacctca
2401 tccaggagga ttacagagaa agaaacatgt aacaatatta gatataggag atgcatattt
2461 tacaatacca ttatatgagc catatagaca atatacatgc tttaccatgt taagtccaaa
2521 taatttagga ccatgtgtaa gatattattg gaaagtgtta ccacaaggat ggaaattaag
2581 tcctgcagtg tatcaattta caatgcaaaa aatattaaga ggatggatag aagaacaccc
2641 tatgatacaa tttggaatat acatggatga tatctatata gggagtgatt taggactaga
2701 agagcacagg ggtatcgtga acgaactagc atcatatata gcgcaatatg gattcatgct
2761 gcctgaagat aagaggcaag aaggataccc ggcgaaatgg cttggatttg aattgcatcc
2821 ggagaaatgg aaatttcaaa aacatacgct cccagagatt acagaaggac ccataacctt
2881 gaataaacta cagaaattag taggagattt agtttggaga caatccctaa taggaaaaag
2941 catcccaaat atcttaaaat taatggaagg agatagggct ttacaaagtg aaagatacat
3001 agagagtata catgtaagag aatgggaagc ctgtagacaa aagctgaagg aaatggaagg
3061 aaattattat gatgaagaga aggatatcta tgggcaacta gattggggaa ataaagcaat
3121 agaatacata gtatttcaag aaaaaggaaa acctttatgg gtaaatgtag tacatagtat
3181 taagaatttg agtcaagccc aacaaattat caaagcagca caaaaactga cacaagaagt
3241 aataataaga acaggcaaga taccctggat tttgttgccg ggaagggaag aagattggat
3301 attagagtta caaatgggaa acataaattg gatgccatca ttttggtcat gttataaagg
3361 ctcggtgagg tggaaaaaga ggaatgtaat agcggaacta gtcccaggac caacatatta
3421 taccgatgga ggaaagaaaa atgggcgggg aagcctgggg tatattgcct ccacaggtga
3481 aaagtttaga atacatgaag aagggacaaa tcagcagtta gaattgaggg ccatagaaga
3541 ggcatgtaaa cagggaccag aaaaaatgaa tatagtaaca gatagcaggt atgcatatga
3601 atttatgttg cggaactggg acgaagaagt aataagaaac cctatacaag cgagaattat
3661 ggaattagtg cataataaag aaaaaatagg ggtacattgg gtgcctggac acaaggggat
3721 tcctcaaaat gaagaaatag ataggtatat ctcagaaata tttttagcaa aagagggaag
3781 agggatttta caaaaaaggg cagaagatgc tggatatgac ttaatatgtc cacaggagat
3841 aagcattccg gcgggacaag tgaaaaggat agcaattgac ttgaaaataa atttgaaaaa
3901 ggaccagtgg gccatgatag ggaccaaaag cagttttgca aataagggag tattcgtaca
3961 aggaggtatc atagattcgg gatatcaagg aacaatacaa gtagtaatat ataatagtaa
4021 taataaagaa gtagtaatac cacagggaag aaaatttgca cagttgatcc tcatgcctct
4081 aatacatgaa gagttggagc catggggaga aacaagaaaa acagaaagag gggaacaagg
4141 atttggatca acagggatgt attggataga aaatattccc ctagcagaag aagagcataa
4201 caaatggcat caagatgctg tgtccttgca tttagaattt gggattccca ggacagctgc
4261 agaagatata gttcaacaat gtgatgtgtg tcaagaaaat aaaatgccta gtacattaag
4321 aggcagtaat aaaaggggca tagaccattg gcaagtagac tatacccact atgaagacaa
4381 gataatattg gtctgggtag aaacaaattc aggactaatc tatgcagaga gggtaaaagg
4441 agaaacagga caagaattta gggtgcaaac tatgaaatgg tatgcgatgt ttgccccgaa
4501 atcattgcag tctgataacg gaccagcatt tgtagcagaa tctactcagc tcttaatgaa
4561 atatttgggc atagaacata ctacagggat cccctggaac ccacaatctc aagcattagt
4621 agagagaaca catcagacgt taaagaatac attagaaaaa cttataccta tgtttaatgc
4681 gtttgaatca gccctcgcag ggaccctcat tactctaaat ataaaaagaa agggtgggct
4741 agggacaagc cctatggata tatttatatt taataaggaa caacaaagaa tacagcaaca
4801 aagtaaatca aaacaagaaa aaattcgatt ttgttattac agaacaagaa aaagagggca
4861 tccaggagag tggcaaggac caacacaggt actttggggc ggggacggtg cgattgtagt
4921 gaaagacaga ggcacagata gatatctggt gatagctaac aaagatgtta agttcatacc
4981 gccaccaaaa gaaatacaaa aagaataaag caagggagat aggaccccag ttgccactat
5041 gggcatggaa agaaacagca tttagtataa atcaagaacc ctattggtat agtaccataa
5101 ggctacaagg gttgatgtgg aataaaagag ggcataaact tatgtttgta aaagaaaacc
5161 aagggtatga gtattgggaa acatcaggaa aacagtggaa aatggagata agacgagatc
5221 tggatctgat agcccaaata aattttagaa atgcatggca atataaaagc cagggagaat
5281 ggaaaacaat aggggtctgg tatgaatcac caggggatta caagggaaaa gagaatcagt
5341 tttggttcca ttggagaata gctctctgca gctgtaacaa aacaaggtgg gatatacggg
5401 aattcatgat agggaagcat aggtgggatt tatgtaaatc gtgtatacaa ggggagatag
5461 ttaagaatac aaatccaaga agcttacaac gcttagcttt attgcaccta gcaaaagacc
5521 atgtatttca agtaatgcca ttgtggagag ccaggagagt cacagtgcag aagtttccat
5581 ggtgtcgtag cccaatgggt tacacgatac cttggtctct gcaggaatgc tgggaaatgg
5641 aatccatctt tgaataatgg aagaagtacc aagaagacag ccaggaggct tagtagaagt
5701 agagggagta tttcaatttt atgaagactg ggaatgttgg gactatgtaa gtcaaagagt
5761 atctgacgaa agactacaac gatggctagc tatgcttact aataatcagc ttagaagaca
5821 agtaattagg gaagcacaga tctggatgtg gaaacataag ggagctgcag ttagaagaaa
5881 ttgtggttgc aggctatgta accccggctg gggaagccaa gtaagaaatg ttgaactgtg
5941 ataagcctgt ctaggatggc cagcaaagaa agtaagccaa gcagaacaac gtggagagac
6001 atggagcccc cactccgaga aacatggaat caagtattac aggagctagt aaaaagacaa
6061 caacaggagg aagaagaaca gcagggactg gtatcaggta agaaaaaatc atgggtaagt
6121 attgacctcc tggggacaga aggaaaagat attaagaagg taaatatatg ggaaccatgt
6181 gaaaagtggt ttgcacaggt ggtatggggg gtattgtggg tgctgcaaat tgtgttgtgg
6241 ggatgtctca tgtgggaagt gagaaaagga aaccagtgtc aagcagaaga agtgatagca
6301 ttggtgagtg atcctggagg atttcagagg gtgcagcacg tagaaacagt gcctgtgacc
6361 tgtgtgacaa aaaatttcac tcaatgggga tgtcaacccg agggggccta tccagatcct
6421 gaactggagt atagaaatat atctagggaa atcttagagg aagtatataa acaagactgg
6481 ccctggaata cttatcattg gcctttatgg caaatggaaa atatgaggca atggatgaaa
6541 gaaaatgaaa aggagtataa ggaaagaaca aacaaaacga aggaagatat agatgatctg
6601 gtagcaggaa gaataagggg aagattttgt gtgccatatc cctatgcttt actacgatgt
6661 gaggagtggt gttggtaccc tgaatctatt aatcaagaaa caggacatgc tgaaaaaata
6721 aaaataaact gcacaaaagc aaaagcagtt tcttgtacag aaaaaatgcc cttagcagca
6781 gtccagcggg tatattggga aaaagaggat gaagaaagca tgaagttttt gaatataaaa
6841 gcctgtaata tatcattgag gtgtcaagat gaaggaaaga gtccgggagg atgtgtacaa
6901 ggatacccca ttccaaaggg agcagaaata ataccagaag ctatgaaata cctcagggga
6961 aagaaaagtc gatatggagg gatcaaggat aaaaatgggg aattaaaatt acctctctct
7021 gtaagggtat gggtgaggat ggcgaatttg tcaggatggg tgaatggaac gcctccttac
7081 tggagtgcaa ggattaatgg gagtacaggg ataaatggaa caaggtggta tggagtagga
7141 acactacatc acttagggta taacattagc agtaacccag agggagggat atgtaacttt
7201 acaggagaac tttggatagg gggtgacaga ttcccatatt attataagcc ctcatggaat
7261 tgttcacaaa attggacagg tcacccagta tggcacgtat ttagatactt ggatatgaca
7321 gaacatatga caagcagatg tatacaaaga cctaaaagac ataatataac agtaggaaat
7381 ggaacaataa cggggaattg tagtgtaaca aattgggatg gatgtaactg tacaaggtca
7441 ggaaatcatt tgtataatag cacaagcgga ggactgttag taatcatatg caggcaaaat
7501 agcaccataa caggaataat gggaacgaac actaattgga caacaatgtg gaacatctac
7561 caaaattgct caagatgtaa caacagtagc ctagacagaa caggtagtgg gaccttggga
7621 acagtgaaca accttaaatg tagcttacca cacagaaatg agagtaacaa gtggacatgt
7681 aagagccaaa gagactcata tatagctgga agagacttct ggggaaaagt aaaagcaaaa
7741 tacagttgtg agagtaattt agggggtcta gatagtatga tgcatcagca aatgttactg
7801 caacgatacc aagtaataag agtaagagct tacacatatg gtgttgtaga aatgccacaa
7861 tcgtatatgg aggagcgagg ggaaaacagg aggtcaagaa ggaacctcca aaggaagaaa
7921 agagggatag gcttggttat tgtgctagcc atcatggcaa taatcgctgc tgcaggagct
7981 ggtctcggtg tcgcaaacgc cgtgcagcaa tcctatacca ggacggctgt ccagtctctt
8041 gctaacgcaa ctgctgccca gcaggaagtg ttggaagcat cgtatgccat ggtacagcat
8101 atagccaaag gaataagaat cctagaggca agagtggcta gggtggaagc cctggtagat
8161 tgaatgatgg tataccaaga attggattgc tggcattatc aacactactg tgtaacctca
8221 acaagaagtg aagtagccaa ttatgtaaac tggacaagat ttaaagataa ctgtacctgg
8281 caacagtggg aggaagaaat agaacaacac gagggaaact tgagtctatt actcagagaa
8341 gcagcattac aagtacacat agctcaaaga gatgctagga gaatcccaga tgcttggaaa
8401 gcaatacaag aagcatttaa ctggtcctct tggttctcgt ggctcaaata tataccctgg
8461 attatcatgg gaattgtagg attaatgtgt tttagaatac taatgtgtgt gatatcaatg
8521 tgtttgcagg cttacaagca agtaaagcag atcagatata cacaggtaac agtggtgata
8581 gaagcaccgg tggaattgga ggaaaaacaa aaaagaaacg gggatggtac aaatggctgc
8641 gcaagcttag agcacgagag aagaacatcc catcgcagtt ttatccagat atggagagca
8701 acatggtggg catggaaaac ctcaccttgg agacacaact ggaggacaat gccctatata
8761 accctgctac ccatattggt gatatggcaa tggatggaag agaatggatg gaatggagag
8821 aatcagcaca aaaagaaaaa agaaagggtg gactgtcagg acagagaaca aatgcctacc
8881 ctggaaaatg actatgtaga gttataggaa ggtcatgtca ctgttaccag aaatcatagt
8941 caggatgaca cagcaaatgt aaccagttac cagaaatcat agtcaggatg acacagcaaa
9001 tgtaaccgca agttctgctt ttttgcgcta agtcatgtag cagctgatgc ttgagtcata
9061 accgcagatg taaacaagtt gcctatataa gccgcttgct agctggggaa aagcagagtg
9121 ctttggagag ctcgaaggaa agagtctccg ggcctctcct gcctgcctga aaagctcaat
9181 aaaggagttg gctgatatct ga
//GenBank-Updates@genbank.bio.net (01/31/91)
LOCUS VLVCGA 9202 bp ss-RNA VRL 31-JAN-1991
DEFINITION Visna lentivirus, Icelandic strains LV1-1 and 1514, complete
proviral genome.
ACCESSION M51543
KEYWORDS complete genome; endonuclease; env gene; envelope glycoprotein;
gag gene; integrase; nucleoprotein; pol gene; polyprotein;
protease; reverse transcriptase; sor gene; trans-activator;
transmembrane protein.
SOURCE Visna lentivirus extrachromosomal proviral DNA.
ORGANISM Visna virus
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (bases 1 to 9202)
AUTHORS Braun,M.J., Clements,J.E. and Gonda,M.A.
TITLE The visna virus genome: Evidence for a hypervariable site in the
env gene and sequence homology among lentivirus envelope proteins
JOURNAL J. Virol. 61, 4046-4054 (1987)
STANDARD full staff_review
FEATURES Location/Qualifiers
LTR <1..160
/note="5' LTR"
mRNA 1..9202
/note="Visna genomic mRNA"
repeat_region 1..97
/note="R repeat 5' copy"
virion 1..9202
/note="visna lentivirus virion"
misc_binding 161..177
CDS 339..1817
/product="gag protein"
/gene="gag"
/codon_start=339
/partial
CDS 1691..5008
/product="pol protein"
/gene="pol"
/codon_start=1691
/partial
CDS 4956..5657
/product="sor protein"
/codon_start=4956
/partial
CDS 5654..5941
/product="tat protein"
/gene="tat"
/codon_start=5654
/partial
CDS 5935..8907
/pseudo=8161-8163
/product="envelope protein"
/gene="env"
/codon_start=5935
/partial
misc_feature 8161..8163
/note="internal stop codon in env protein"
LTR 8852..9202
/note="3' LTR"
repeat_region 9106..9202
/note="R repeat 3' copy"
misc_signal 9178..9183
BASE COUNT 3416 a 1419 c 2399 g 1968 t
ORIGIN 5' end of virion; 27 bp upstream of SstI site.
1 gggaaaagca gagtgctttg gagagctcga aggaaagagt ctccgggcct ctcctgcctg
61 cctgaaaagc tcaataaagg agttggctga tatctgagct tgctggttat tatcgggatt
121 cgttactaat tccgtgcaac accggagcgg atctcgcagc tggcgcccaa cgtggggctc
181 gacaaagaat cagaagaaaa atgagagtta tgggaccacg gacgctgctc ctgtgaggac
241 ggcgaggaga gtaacggaca cggacaaaaa gtgaaagaaa gcttcgggga cgcctgaagt
301 aaggtaagag agacacctac tggggaagta gggaatagcc cttcagtgaa ggagaaagtg
361 ttgcttgggc acaggaggag ggttcgcgac cccttagaaa gacggagggg cgcgggcgtc
421 ctcctgggcc gaggggacac aagagcaaca ctggtaagga agccgccgtg gtgaggctag
481 ctagagacat ggcgaagcaa ggctcaaagg agaaaaaggg ataccccgag ctcaaggaag
541 taattaaagc aacttgtaaa ataagggtag ggcccgggaa ggagaccttg acagaaggga
601 attgtctatg ggcattaaaa actatagact ttatatttga ggatttaaaa acagagccgt
661 ggacgattac aaaaatgtat acagtatggg atagattaaa agggctaact ccggaggaaa
721 caagcaaaag agaattcgcc tccttgcaag ctacgttggc ttgcataatg tgtagtcaaa
781 tgggcatgaa gcccgagaca gtgcaggcag caaagggaat aataagtatg aaagaaggac
841 tacacgaaaa taaggaggcc aagggggaga aggtagagca actctacccc aacttagaga
901 aacataggga agtttatcct attgtgaatt tgcaagcagg agggagaagt tggaaggcgg
961 tagagtcagt agtcttccag caactgcaaa cagtggcaat gcagcatgga cttgtgtccg
1021 aggattttga gaggcaattg gcatattatg ctactacctg gactagtaaa gatatattag
1081 aagtattggc tatgatgcct gggaatagag cacagaagga attaatacaa ggaaaattaa
1141 atgaagaagc agaaaggtgg gtaagacaaa atccacccgg gccgaatgtc ctcacggtgg
1201 atcaaataat gggagtggga caaaccaatc agcaggcatc tcaagccaat atggatcagg
1261 caagacagat atgcctgcag tgggtaataa cagcgttaag atcagtgagg catatgtcac
1321 atagaccagg aaaccctatg ttagtgaagc agaagaatac tgagagttat gaagacttca
1381 tagctcgcct actagaggct attgatgcgg aaccagtgac ggaccctata aaaacatatt
1441 taaaagtaac attgtcatat acaaatgcta gcacagactg tcaaaagcag atggatagga
1501 cattggggac gagggttcaa caagcaacgg tagaagaaaa gatgcaagca tgtcgagatg
1561 tgggatccga aggatttaag atgcaattat tagcacaagc tttgagaccg caagggaagg
1621 caggacacaa aggggtaaat caaaagtgtt ataattgtgg aaaaccagga catctcgcaa
1681 gacagtgtag acaaggaata atatgccatc attgtggaaa aagaggacat atgcaaaagg
1741 actgccggca gaagaaacag cagggaaaca acaggagggg gccacgtgtg gtgccgtccg
1801 cgccccctat gttgtaacag aagcaccacc caaaatagaa ataaaagtag gaacaaggtg
1861 gaaaaaatta ttagtagata cgggggcaga taaaactata gtaacatccc atgatatgtc
1921 agggatacca aagggaagga taatattaca gggcataggg ggaataatag aaggagaaaa
1981 atgggaacaa gtacacttgc aatataaaga taaaatgatc aaaggtacca tagtggtgtt
2041 agctacgagt ccggtagaag tattaggaag agataatatg agagaattgg gaataggatt
2101 aattatggca aatttagaag aaaagaaaat tcccagtaca agagtaagat taaaagaggg
2161 atgtaaggga ccccacatag cgcaatggcc tttgacgcaa gaaaaattag agggattaaa
2221 agaaatagta gacagattag agaaggaagg gaaagtagga agagcgcccc cacactggac
2281 ttgtaatacc cctatatttt gtattaagaa gaaatcagga aaatggagga tgttaataga
2341 ttttagagaa ttaaataagc aaacagaaga tttagcagaa gcacagttag ggttacctca
2401 tccaggagga ttacagagaa agaaacatgt aacaatatta gatataggag atgcatattt
2461 tacaatacca ttatatgagc catatagaca atatacatgc tttaccatgt taagtccaaa
2521 taatttagga ccatgtgtaa gatattattg gaaagtgtta ccacaaggat ggaaattaag
2581 tcctgcagtg tatcaattta caatgcaaaa aatattaaga ggatggatag aagaacaccc
2641 tatgatacaa tttggaatat acatggatga tatctatata gggagtgatt taggactaga
2701 agagcacagg ggtatcgtga acgaactagc atcatatata gcgcaatatg gattcatgct
2761 gcctgaagat aagaggcaag aaggataccc ggcgaaatgg cttggatttg aattgcatcc
2821 ggagaaatgg aaatttcaaa aacatacgct cccagagatt acagaaggac ccataacctt
2881 gaataaacta cagaaattag taggagattt agtttggaga caatccctaa taggaaaaag
2941 catcccaaat atcttaaaat taatggaagg agatagggct ttacaaagtg aaagatacat
3001 agagagtata catgtaagag aatgggaagc ctgtagacaa aagctgaagg aaatggaagg
3061 aaattattat gatgaagaga aggatatcta tgggcaacta gattggggaa ataaagcaat
3121 agaatacata gtatttcaag aaaaaggaaa acctttatgg gtaaatgtag tacatagtat
3181 taagaatttg agtcaagccc aacaaattat caaagcagca caaaaactga cacaagaagt
3241 aataataaga acaggcaaga taccctggat tttgttgccg ggaagggaag aagattggat
3301 attagagtta caaatgggaa acataaattg gatgccatca ttttggtcat gttataaagg
3361 ctcggtgagg tggaaaaaga ggaatgtaat agcggaacta gtcccaggac caacatatta
3421 taccgatgga ggaaagaaaa atgggcgggg aagcctgggg tatattgcct ccacaggtga
3481 aaagtttaga atacatgaag aagggacaaa tcagcagtta gaattgaggg ccatagaaga
3541 ggcatgtaaa cagggaccag aaaaaatgaa tatagtaaca gatagcaggt atgcatatga
3601 atttatgttg cggaactggg acgaagaagt aataagaaac cctatacaag cgagaattat
3661 ggaattagtg cataataaag aaaaaatagg ggtacattgg gtgcctggac acaaggggat
3721 tcctcaaaat gaagaaatag ataggtatat ctcagaaata tttttagcaa aagagggaag
3781 agggatttta caaaaaaggg cagaagatgc tggatatgac ttaatatgtc cacaggagat
3841 aagcattccg gcgggacaag tgaaaaggat agcaattgac ttgaaaataa atttgaaaaa
3901 ggaccagtgg gccatgatag ggaccaaaag cagttttgca aataagggag tattcgtaca
3961 aggaggtatc atagattcgg gatatcaagg aacaatacaa gtagtaatat ataatagtaa
4021 taataaagaa gtagtaatac cacagggaag aaaatttgca cagttgatcc tcatgcctct
4081 aatacatgaa gagttggagc catggggaga aacaagaaaa acagaaagag gggaacaagg
4141 atttggatca acagggatgt attggataga aaatattccc ctagcagaag aagagcataa
4201 caaatggcat caagatgctg tgtccttgca tttagaattt gggattccca ggacagctgc
4261 agaagatata gttcaacaat gtgatgtgtg tcaagaaaat aaaatgccta gtacattaag
4321 aggcagtaat aaaaggggca tagaccattg gcaagtagac tatacccact atgaagacaa
4381 gataatattg gtctgggtag aaacaaattc aggactaatc tatgcagaga gggtaaaagg
4441 agaaacagga caagaattta gggtgcaaac tatgaaatgg tatgcgatgt ttgccccgaa
4501 atcattgcag tctgataacg gaccagcatt tgtagcagaa tctactcagc tcttaatgaa
4561 atatttgggc atagaacata ctacagggat cccctggaac ccacaatctc aagcattagt
4621 agagagaaca catcagacgt taaagaatac attagaaaaa cttataccta tgtttaatgc
4681 gtttgaatca gccctcgcag ggaccctcat tactctaaat ataaaaagaa agggtgggct
4741 agggacaagc cctatggata tatttatatt taataaggaa caacaaagaa tacagcaaca
4801 aagtaaatca aaacaagaaa aaattcgatt ttgttattac agaacaagaa aaagagggca
4861 tccaggagag tggcaaggac caacacaggt actttggggc ggggacggtg cgattgtagt
4921 gaaagacaga ggcacagata gatatctggt gatagctaac aaagatgtta agttcatacc
4981 gccaccaaaa gaaatacaaa aagaataaag caagggagat aggaccccag ttgccactat
5041 gggcatggaa agaaacagca tttagtataa atcaagaacc ctattggtat agtaccataa
5101 ggctacaagg gttgatgtgg aataaaagag ggcataaact tatgtttgta aaagaaaacc
5161 aagggtatga gtattgggaa acatcaggaa aacagtggaa aatggagata agacgagatc
5221 tggatctgat agcccaaata aattttagaa atgcatggca atataaaagc cagggagaat
5281 ggaaaacaat aggggtctgg tatgaatcac caggggatta caagggaaaa gagaatcagt
5341 tttggttcca ttggagaata gctctctgca gctgtaacaa aacaaggtgg gatatacggg
5401 aattcatgat agggaagcat aggtgggatt tatgtaaatc gtgtatacaa ggggagatag
5461 ttaagaatac aaatccaaga agcttacaac gcttagcttt attgcaccta gcaaaagacc
5521 atgtatttca agtaatgcca ttgtggagag ccaggagagt cacagtgcag aagtttccat
5581 ggtgtcgtag cccaatgggt tacacgatac cttggtctct gcaggaatgc tgggaaatgg
5641 aatccatctt tgaataatgg aagaagtacc aagaagacag ccaggaggct tagtagaagt
5701 agagggagta tttcaatttt atgaagactg ggaatgttgg gactatgtaa gtcaaagagt
5761 atctgacgaa agactacaac gatggctagc tatgcttact aataatcagc ttagaagaca
5821 agtaattagg gaagcacaga tctggatgtg gaaacataag ggagctgcag ttagaagaaa
5881 ttgtggttgc aggctatgta accccggctg gggaagccaa gtaagaaatg ttgaactgtg
5941 ataagcctgt ctaggatggc cagcaaagaa agtaagccaa gcagaacaac gtggagagac
6001 atggagcccc cactccgaga aacatggaat caagtattac aggagctagt aaaaagacaa
6061 caacaggagg aagaagaaca gcagggactg gtatcaggta agaaaaaatc atgggtaagt
6121 attgacctcc tggggacaga aggaaaagat attaagaagg taaatatatg ggaaccatgt
6181 gaaaagtggt ttgcacaggt ggtatggggg gtattgtggg tgctgcaaat tgtgttgtgg
6241 ggatgtctca tgtgggaagt gagaaaagga aaccagtgtc aagcagaaga agtgatagca
6301 ttggtgagtg atcctggagg atttcagagg gtgcagcacg tagaaacagt gcctgtgacc
6361 tgtgtgacaa aaaatttcac tcaatgggga tgtcaacccg agggggccta tccagatcct
6421 gaactggagt atagaaatat atctagggaa atcttagagg aagtatataa acaagactgg
6481 ccctggaata cttatcattg gcctttatgg caaatggaaa atatgaggca atggatgaaa
6541 gaaaatgaaa aggagtataa ggaaagaaca aacaaaacga aggaagatat agatgatctg
6601 gtagcaggaa gaataagggg aagattttgt gtgccatatc cctatgcttt actacgatgt
6661 gaggagtggt gttggtaccc tgaatctatt aatcaagaaa caggacatgc tgaaaaaata
6721 aaaataaact gcacaaaagc aaaagcagtt tcttgtacag aaaaaatgcc cttagcagca
6781 gtccagcggg tatattggga aaaagaggat gaagaaagca tgaagttttt gaatataaaa
6841 gcctgtaata tatcattgag gtgtcaagat gaaggaaaga gtccgggagg atgtgtacaa
6901 ggatacccca ttccaaaggg agcagaaata ataccagaag ctatgaaata cctcagggga
6961 aagaaaagtc gatatggagg gatcaaggat aaaaatgggg aattaaaatt acctctctct
7021 gtaagggtat gggtgaggat ggcgaatttg tcaggatggg tgaatggaac gcctccttac
7081 tggagtgcaa ggattaatgg gagtacaggg ataaatggaa caaggtggta tggagtagga
7141 acactacatc acttagggta taacattagc agtaacccag agggagggat atgtaacttt
7201 acaggagaac tttggatagg gggtgacaga ttcccatatt attataagcc ctcatggaat
7261 tgttcacaaa attggacagg tcacccagta tggcacgtat ttagatactt ggatatgaca
7321 gaacatatga caagcagatg tatacaaaga cctaaaagac ataatataac agtaggaaat
7381 ggaacaataa cggggaattg tagtgtaaca aattgggatg gatgtaactg tacaaggtca
7441 ggaaatcatt tgtataatag cacaagcgga ggactgttag taatcatatg caggcaaaat
7501 agcaccataa caggaataat gggaacgaac actaattgga caacaatgtg gaacatctac
7561 caaaattgct caagatgtaa caacagtagc ctagacagaa caggtagtgg gaccttggga
7621 acagtgaaca accttaaatg tagcttacca cacagaaatg agagtaacaa gtggacatgt
7681 aagagccaaa gagactcata tatagctgga agagacttct ggggaaaagt aaaagcaaaa
7741 tacagttgtg agagtaattt agggggtcta gatagtatga tgcatcagca aatgttactg
7801 caacgatacc aagtaataag agtaagagct tacacatatg gtgttgtaga aatgccacaa
7861 tcgtatatgg aggagcgagg ggaaaacagg aggtcaagaa ggaacctcca aaggaagaaa
7921 agagggatag gcttggttat tgtgctagcc atcatggcaa taatcgctgc tgcaggagct
7981 ggtctcggtg tcgcaaacgc cgtgcagcaa tcctatacca ggacggctgt ccagtctctt
8041 gctaacgcaa ctgctgccca gcaggaagtg ttggaagcat cgtatgccat ggtacagcat
8101 atagccaaag gaataagaat cctagaggca agagtggcta gggtggaagc cctggtagat
8161 tgaatgatgg tataccaaga attggattgc tggcattatc aacactactg tgtaacctca
8221 acaagaagtg aagtagccaa ttatgtaaac tggacaagat ttaaagataa ctgtacctgg
8281 caacagtggg aggaagaaat agaacaacac gagggaaact tgagtctatt actcagagaa
8341 gcagcattac aagtacacat agctcaaaga gatgctagga gaatcccaga tgcttggaaa
8401 gcaatacaag aagcatttaa ctggtcctct tggttctcgt ggctcaaata tataccctgg
8461 attatcatgg gaattgtagg attaatgtgt tttagaatac taatgtgtgt gatatcaatg
8521 tgtttgcagg cttacaagca agtaaagcag atcagatata cacaggtaac agtggtgata
8581 gaagcaccgg tggaattgga ggaaaaacaa aaaagaaacg gggatggtac aaatggctgc
8641 gcaagcttag agcacgagag aagaacatcc catcgcagtt ttatccagat atggagagca
8701 acatggtggg catggaaaac ctcaccttgg agacacaact ggaggacaat gccctatata
8761 accctgctac ccatattggt gatatggcaa tggatggaag agaatggatg gaatggagag
8821 aatcagcaca aaaagaaaaa agaaagggtg gactgtcagg acagagaaca aatgcctacc
8881 ctggaaaatg actatgtaga gttataggaa ggtcatgtca ctgttaccag aaatcatagt
8941 caggatgaca cagcaaatgt aaccagttac cagaaatcat agtcaggatg acacagcaaa
9001 tgtaaccgca agttctgctt ttttgcgcta agtcatgtag cagctgatgc ttgagtcata
9061 accgcagatg taaacaagtt gcctatataa gccgcttgct agctggggaa aagcagagtg
9121 ctttggagag ctcgaaggaa agagtctccg ggcctctcct gcctgcctga aaagctcaat
9181 aaaggagttg gctgatatct ga
//