GenBank-Updates@genbank.bio.net (02/01/91)
LOCUS HUMGPIIB 703 bp ss-mRNA PRI 01-FEB-1991
DEFINITION Human platelet glycoprotein IIb mRNA, 3' end.
ACCESSION M18085 J05494 M35365 M54791
KEYWORDS fibrinogen receptor; glycoprotein IIb; platelet glycoprotein IIb;
platelet membrane glycoprotein.
SOURCE Human (erythroleukemia (HEL) cell line), cDNA to mRNA, clone
lambda-H3.1.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 703)
AUTHORS Bray,P.F., Rosa,J.-P., Johnston,G.I., Shiu,D.T., Cook,R.G., Lau,C.,
Kan,Y.W., McEver,R.P. and Shuman,M.A.
TITLE Platelet glycoprotein IIb: Chromosomal localization and tissue
expression
JOURNAL J. Clin. Invest. 80, 1812-1817 (1987)
STANDARD simple staff_review
REFERENCE 2 (sites)
AUTHORS Bray,P.F., Leung,C.S.-I. and Shuman,M.A.
TITLE Human platelets and megakaryocytes contain alternately spliced
glycoprotein IIb mRNAs
JOURNAL J. Biol. Chem. 265, 9587-9590 (1990)
STANDARD full staff_review
FEATURES Location/Qualifiers
mat_peptide one-of(63..518,72..518)
/note="alternate"
/product="glycoprotein IIb-beta"
mRNA <1..703
/product="glycoprotein IIb"
mat_peptide one-of(<1..62,<1..71)
/codon_start=3
/product="glycoprotein IIb-alpha"
CDS <1..521
/codon_start=3
/product="glycoprotein IIb"
mat_peptide 108..518
/product="glycoprotein IIb-beta"
BASE COUNT 112 a 224 c 218 g 149 t
ORIGIN Chromosome 17q21.3.
1 aggtggactg ggggctgccc atccccagcc cctcccccat tcacccggcc catcacaagc
61 gggatcgcag acagatcttc ctgccagagc ccgagcagcc ctcgaggctt caggatccag
121 ttctcgtaag ctgcgactcg gcgccctgta ctgtggtgca gtgtgacctg caggagatgg
181 cgcgcgggca gcgggccatg gtcacggtgc tggccttcct gtggctgccc agcctctacc
241 agaggcctct ggatcagttt gtgctgcagt cgcacgcatg gttcaacgtg tcctccctcc
301 cctatgcggt gcccccgctc agcctgcccc gaggggaagc tcaggtgtgg acacagctgc
361 tccgggcctt ggaggagagg gccattccaa tctggtgggt gctggtgggt gtgctgggtg
421 gcctgctgct gctcaccatc ctggtcctgg ccatgtggaa ggtcggcttc ttcaagcgga
481 accggccacc cctggaagaa gatgatgaag agggggagtg atggtgcagc ctacactatt
541 ctagcaggag ggttgggcgt gctacctgca ccgccccttc tccaacaagt tgcctccaag
601 ctttgggttg gagctgttcc attgggtcct cttggtgtcg tttccctccc aacagagctg
661 ggctaccccc cctcctgctg cctaataaag agactgagcc ctg
//