GenBank-Updates@genbank.bio.net (02/01/91)
LOCUS HUMIGHP1 560 bp ds-DNA PRI 01-FEB-1991
DEFINITION Human processed IgH chain gene, VDH-region, exons 1 and 2.
ACCESSION M38066
KEYWORDS diversity exon; immunoglobin heavy chain; joining exon;
processed gene; variable region.
SOURCE Human (patient 1) rearranged DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 560)
AUTHORS White,M.B., Word,C.J., Humphries,C.G., Blattner,F.R. and
Tucker,P.W.
TITLE Immunoglobulin d switching can occur through homologous
recombination in human B cells
JOURNAL Mol. Cell. Biol. 10, 3690-3699 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
sig_peptide join(7..52,154..164)
/gene="IgH"
CDS join(7..52,154..522)
/gene="IgH"
/partial
/product="immunoglobulin heavy chain"
intron 53..153
/number=1
/gene="IgH"
mat_peptide 165..522
/gene="IgH"
/codon_start=165
/partial
/product="immunoglobulin heavy chain"
intron 523..560
/number=2
/gene="IgH"
/partial
BASE COUNT 123 a 129 c 165 g 143 t
ORIGIN
1 ctcaccatgg agttcgggct gagttgggtt ttcctcgttg cgctcttaag aggtgaatca
61 tggagaaata gagagactga gtgtgactga acatgagtga gaaaaattgg atttgtgtga
121 cattttctga taacggtgtc cttctccttg caggtgtcca gtgtcaggtg caactggtgg
181 agtcgggggg aggcgtagtc caggctggga ggtccctgag gctctcctgt gcaacgtctg
241 gattcatgtt cagtacctat gccatgcact gggtccgcca ggctccaggc aaggggctgg
301 agtgggtggc tgttatttgg tacgatggaa gtcaagcctc ctacacagat tccgtgaggg
361 gccgattcac catctccaga gacaattcca agaaaatcct ttatttggaa atgagtggcc
421 tgagagccga ggacacggct acctattact gtgcgaccca acatgactac agtcaccaaa
481 gagattactg gggccaggga accctggtca ccgtctcctc aggtgagtcc tcggagtctc
541 tctacttctt tgctcttgga
//