GenBank-Updates@genbank.bio.net (02/02/91)
LOCUS HUMGBP1 2881 bp ss-mRNA PRI 02-FEB-1991
DEFINITION Human guanylate binding protein isoform I (GBP-2) mRNA, complete
cds.
ACCESSION M55542
KEYWORDS guanylate binding protein isoform I.
SOURCE Human foreskin fibroblast, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2881)
AUTHORS Cheng,Y.-S.E., Patterson,C.E. and Staeheli,P.
TITLE Interferon-induced guanylate-binding proteins lack a N(T)KXD
consensus motif and bind GMP in addition to GDP and GTP
JOURNAL Unpublished (0)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA <1..>2881
/gene="GBP-1"
/product="guanylate binding protein isoform I"
CDS 69..1847
/gene="GBP-1"
/evidence=EXPERIMENTAL
/codon_start=69
/product="guanylate binding protein isoform I"
BASE COUNT 945 a 592 c 650 g 694 t
ORIGIN
1 acagaagtgc tagaagccag tgctcgtgaa ctaaggagaa aaagaacaga caagggaaca
61 gcctggacat ggcatcagag atccacatga caggcccaat gtgcctcatt gagaacacta
121 atgggcgact gatggcgaat ccagaagctc tgaagatcct ttctgccatt acacagccta
181 tggtggtggt ggcaattgtg ggcctctacc gcacaggcaa atcctacctg atgaacaagc
241 tggctggaaa gaaaaagggc ttctctctgg gctccacggt gcagtctcac actaaaggaa
301 tctggatgtg gtgtgtgccc caccccaaga agccaggcca catcctagtt ctgctggaca
361 ccgagggtct gggagatgta gagaagggtg acaaccagaa tgactcctgg atcttcgccc
421 tggccgtcct cctgagcagc accttcgtgt acaatagcat aggaaccatc aaccagcagg
481 ctatggacca actgtactat gtgacagagc tgacacatag aatccgatca aaatcctcac
541 ctgatgagaa tgagaatgag gttgaggatt cagctgactt tgtgagcttc ttcccagact
601 ttgtgtggac actgagagat ttctccctgg acttggaagc agatggacaa cccctcacac
661 cagatgagta cctgacatac tccctgaagc tgaagaaagg taccagtcaa aaagatgaaa
721 cttttaacct gcccagactc tgtatccgga aattcttccc aaagaaaaaa tgctttgtct
781 ttgatcggcc cgttcaccgc aggaagcttg cccagctcga gaaactacaa gatgaagagc
841 tggaccccga atttgtgcaa caagtagcag acttctgttc ctacatcttt agtaattcca
901 aaactaaaac tctttcagga ggcatccagg tcaacgggcc tcgtctagag agcctggtgc
961 tgacctacgt caatgccatc agcagtgggg atctgccgtg catggagaac gcagtcctgg
1021 ccttggccca gatagagaac tcagctgcag tgcaaaaggc tattgcccac tatgaacagc
1081 agatgggcca gaaggtgcag ctgcccacag aaagcctcca ggagctgctg gacctgcaca
1141 gggacagtga gagagaggcc attgaagtct tcatcaggag ttccttcaaa gatgtggacc
1201 atctatttca aaaggagtta gcggcccagc tagaaaaaaa gcgggatgac ttttgtaaac
1261 agaatcagga agcatcatca gatcgttgct caggtttact tcaggtcatt ttcagtcctc
1321 tagaagaaga agtgaaggcg ggaatttatt cgaaaccagg gggctatcgt ctctttgttc
1381 agaagctaca agacctgaag aaaaagtact atgaggaacc gaggaagggg atacaggctg
1441 aagagattct gcagacatac ttgaaatcca aggagtctat gactgatgca attctccaga
1501 cagaccagac tctcacagaa aaagaaaagg agattgaagt ggaacgtgtg aaagctgagt
1561 ctgcacaggc ttcagcaaaa atgttgcagg aaatgcaaag aaagaatgag cagatgatgg
1621 aacagaagga gaggagttat caggaacact tgaaacaact gactgagaag atggagaacg
1681 acagggtcca gttgctgaaa gagcaagaga ggaccctcgc tcttaaactt caggaacagg
1741 agcaactact aaaagaggga tttcaaaaag aaagcagaat aatgaaaaat gagatacagg
1801 atctccagac gaaaatgaga cgacgaaagg catgtaccat aagctaaaga ccagagcctt
1861 cctgtcaccc ctaaccaagg cataattgaa acaattttag aatttggaac aagcgtcact
1921 acatttgata ataattagat cttgcatcat aacaccaaaa gtttataaag gcatgtggta
1981 caatgatcaa aatcatgttt tttcttaaaa aaaaaaaaaa gactgtaaat tgtgcaacaa
2041 agatgcattt acctctgtat caactcagga aatctcataa gctggtacca ctcaggagaa
2101 gtttattctt ccagatgacc agcagtagac aaatggatac tgagcagagt cttaggtaaa
2161 agtcttggga aatatttggg cattggtctg gccaagtcta caatgtccca atatcaagga
2221 caaccaccct agcttcttag tgaagacaat gtacagttat ccattagatc aagactacac
2281 ggtctatgag caataatgtg atttctggac attgcccatg tataatcctc actgatgatt
2341 tcaagctaaa gcaaaccacc ttatacagag atctagaatc tctttatgtt ctccagagga
2401 aggtggaaga aaccatgggc aggagtagga attgagtgat aaacaattgg gctaatgaag
2461 aaaacttctc ttattgttca gttcatccag attataactt caatgggaca ctttagacca
2521 ttagacaatt gacactggat taaacaaatt cacataatgc caaatacaca atgtatttat
2581 agcaacgtat aatttgcaaa gatggacttt aaaagatgct gtgtaactaa actgaaataa
2641 ttcaattact tattatttag aatgttaaag cttatgatag tcttttctaa ttcttaacac
2701 tcatacttga aatctttccg agtttcccca gaagagaata tgggattttt tttgacattt
2761 ttgacccatt taataatgct cttgtgttta cctagtatat gtagactttg tcttatgtgt
2821 caaaagtcct aggaaagtgg ttgatgtttc ttatagcaat taaaaattat ttttgaactg
2881 a
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