GenBank-Updates@genbank.bio.net (02/09/91)
LOCUS HUMPRLR 2723 bp ss-mRNA PRI 09-FEB-1991
DEFINITION Human prolactin (PRL) receptor mRNA, complete cds.
ACCESSION M31661 M60727
KEYWORDS prolactin receptor.
SOURCE Human hepatoma cell line HepG2, cDNA to mRNA, (library of
J.C.Edman).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2723)
AUTHORS Boutin,J.-., Edery,M., Shirota,M., Jolicoeur,C., Lesueur,L.,
Ali,S., Gould,D., Djiane,J. and Kelly,P.A.
TITLE Identification of a cDNA encoding a long form of prolactin receptor
in human hepatoma and breast cancer cells
JOURNAL Mol. Endocrinol. 3, 1455-1461 (1989)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS 285..2153
/gene="PRL receptor"
/codon_start=1
/product="prolactin receptor"
sig_peptide 285..356
/gene="PRL receptor"
/codon_start=1
/product="prolactin receptor"
mat_peptide 357..2150
/note="prolactin receptor"
/gene="PRL receptor"
/codon_start=1
/product="prolactin receptor"
BASE COUNT 785 a 655 c 593 g 690 t
ORIGIN
1 ggaggctgaa atccccagac gccggttttc tgggctgggc tttctgctta ctcactcctt
61 ctccctcttt ctggatttta ccgaccgttc gcgaaacagc tttccacaca atggagcttc
121 atgtcctcgt gcaggaagta ctcatcgact gatgtggcag actttgctcc ctgacaaaac
181 taaagaactc tcctattcat ggaggcgaac actgaggatg ctttccacat gaaccctgaa
241 gtgaacttct gatacatttc ctgcagcaag agaaggcagc caacatgaag gaaaatgtgg
301 catctgcaac cgttttcact ctgctacttt ttctcaacac ctgccttctg aatggacagt
361 tacctcctgg aaaacctgag atctttaaat gtcgttctcc caataaggaa acattcacct
421 gctggtggag gcctgggaca gatggaggac ttcctaccaa ttattcactg acttaccaca
481 gggaaggaga gacactcatg catgaatgtc cagactacat aaccggtggc cccaactcct
541 gccactttgg caagcagtac acctccatgt ggaggacata catcatgatg gtcaatgcca
601 ctaaccagat gggaagcagt ttctcggatg aactttatgt ggacgtgact tacatagttc
661 agccagaccc tcctttggag ctggctgtgg aagtaaaaca gccagaagac agaaaaccct
721 acctgtggat taaatggtct ccacctaccc tgattgactt aaaaactggt tggttcacgc
781 tcctgtatga aattcgatta aaacccgaga aagcagctga gtgggagatc cattttgctg
841 ggcagcaaac agagtttaag attctcagcc tacatccagg acagaaatac cttgtccagg
901 ttcgctgcaa accagaccat ggatactgga gtgcatggag tccagcgacc ttcattcaga
961 tacctagtga cttcaccatg aatgatacaa ccgtgtggat ctctgtggct gtcctttctg
1021 ctgtcatctg tttgattatt gtctgggcag tggctttgaa gggctatagc atggtgacct
1081 gcatctttcc gccagttcct gggccaaaaa taaaaggatt tgatgctcat ctgttggaga
1141 agggcaagtc tgaagaacta ctgagtgcct tgggatgcca agactttcct cccacttctg
1201 actatgagga cttgctggtg gagtatttag aagtagatga tagtgaggac cagcatctaa
1261 tgtcagtcca ttcaaaagaa cacccaagtc aaggtatgaa acccacatac ctggatcctg
1321 acactgactc aggccggggg agctgtgaca gcccttccct tttgtctgaa aagtgtgagg
1381 aaccccaggc caatccctcc acattctatg atcctgaggt cattgagaag ccagagaatc
1441 ctgaaacaac ccacacctgg gacccccagt gcataagcat ggaaggcaaa atcccctatt
1501 ttcatgctgg tggatccaaa tgttcaacat ggcccttacc acagcccagc cagcacaacc
1561 ccagatcctc ttaccacaat attactgatg tgtgtgagct ggctgtgggc cctgcaggtg
1621 caccggccac tctgttgaat gaagcaggta aagatgcttt aaaatcctct caaaccatta
1681 agtctagaga agagggaaag gcaacccagc agagggaggt agaaagcttc cattctgaga
1741 ctgaccagga tacgccctgg ctgctgcccc aggagaaaac cccctttggc tccgctaaac
1801 ccttggatta tgtggagatt cacaaggtca acaaagatgg tgcattatca ttgctaccaa
1861 aacagagaga gaacagcggc aagcccaaga agcccgggac tcctgagaac aataaggagt
1921 atgccaaggt gtccggggtc atggataaca acatcctggt gttggtgcca gatccacatg
1981 ctaaaaacgt ggcttgcttt gaagaatcag ccaaagaggc cccaccatca cttgaacaga
2041 atcaagctga gaaagccctg gccaacttca ctgcaacatc aagcaagtgc aggctccagc
2101 tgggtggttt ggattacctg gatcccgcat gttttacaca ctcctttcac tgatagcttg
2161 actaatggaa tgattggtta aaatgtgatt tttcttcagg taacactaca gagtacgtga
2221 aatgctcaag aatgtagtca gactgacact actaaagctc ccagctcctt tcatgctcca
2281 tttttaacca cttgcctctt tctccagcag ctgattccag aacaaatcat tatgtttcct
2341 aactgtgatt tgtagattta ctttttgctg ttagttataa aactatgtgt tcaatgaaat
2401 aaaagcacac tgcttagtat tcttgaggga caatgccaat aggtatatcc tctggaaaag
2461 gctttcatga tttggcatgg gacagacgga aatgaaattg tcaaaattgt ttaccataga
2521 aagatgacaa aagaaaattt tccacatagg aaaatgccat gaaaattgct tttgaaaaac
2581 aactgcataa cctttacact cctcgtccat tttattagga ttacccaaat ataaccattt
2641 aaagaaagaa tgcattccag aacaaattgt ttacataagt tcctatacct tactgacaca
2701 ttgctgatat gcaagtaaga aat
//