GenBank-Updates@genbank.bio.net (11/09/90)
LOCUS HUMIGHDLA 14929 bp ds-DNA PRI 09-NOV-1990
DEFINITION Human Ig germline H-chain D-region genes, partial cds.
ACCESSION M37277
KEYWORDS diversity exon; germline; immunoglobin heavy chain.
SOURCE Human DNA, clone HUD-3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 14929)
AUTHORS Ichihara,Y., Matsuoka,H. and Kurosawa,Y.
TITLE Organization of human immunoglobulin heavy chain diversity gene
loci
JOURNAL EMBO J. 7, 4141-4150 (1988)
STANDARD simple staff_review
FEATURES from to/span description
pept < 804 > 834 Ig H-chain DXP4 (AA at 804)
pept < 1952 > 1967 Ig H-chain DA4 (AA at 1953)
pept < 2913 > 2932 Ig H-chain DK4 (AA at 2913)
pept < 4762 > 4779 Ig H-chain DN4 (AA at 4762)
pept < 5266 > 5282 Ig H-chain DM1 (AA at 5266)
pept < 7949 > 7979 Ig H-chain DLR1 (AA at 7980)
pept < 10475 > 10505 Ig H-chain DXP1 (AA at 10476)
pept < 10659 > 10689 Ig H-chain DXP'1 (AA at 10660)
pept < 11550 > 11565 Ig H-chain DA1 (AA at 11551)
pept < 12506 > 12528 Ig H-chain DK1 (AA at 12506)
pept < 14011 > 14031 Ig H-chain DN1 (AA at 14011)
pept < 14518 > 14534 Ig H-chain DM2 (AA at 14518)
BASE COUNT 3308 a 4994 c 4069 g 2558 t
ORIGIN
1 gaattcatgc cgccatctgg caggcacaga gcatgggctg ggaggagggg cagggacacc
61 aggcaggttg gcaccaactg aaaattacag aagtctcata catctacctc agccttgcct
121 gacctgggcc tcacctgacc tggacctcac ctggcctgga cctcacctgg cctagacctc
181 acctctgggc ttcacctgag ctcggcctca cctgacttgg accttgcctg tcctgagctc
241 acatgatctg ggcctcacct gacctggttt cacctgacct gggcttcacc tgacctgggc
301 ctcatctgac ctgggcctca ctggcctgga cctcacctgg cctgggcttc acctggcctc
361 aggcctcatc tgcacctgct ccaggtcttg ctggaacctc agtagcactg aggctgcagg
421 ggctcatcca gggttgcaga atgactctag aacctcccac atctcagctt tctgggtgga
481 ggcactggtg gcccagggaa tataaaaagc ctgaatgatg cctgcgtgat ttgggggcaa
541 tttataaacc caaaatggac atggccatgc agcgggtagg gacaatacag acagatatca
601 gcctgaaatg gagcctcagg gcacagtggg cacggacact gtccacctaa gccaggggca
661 gacccgagtg tccccgcagt agacctgaga gcgctgggcc cacagcctcc cctcggtgcc
721 ctgctacctc ctcaggtcag ccctggacat cccgggtttc cccaggctgg cggtaggttt
781 ggggtgaggt ctgtgtcact gtggtattac gatttttgga gtggttatta tacccacagt
841 gtcacagagt ccatcaaaaa cccatccctg ggaaccttct gccacagccc tcctgtgggg
901 caccgccgcg tgccatgtta ggattttgac tgaggacaca gcaccatggg tatggtgcta
961 ccgcagcagt gcagcctgtg acccaaacac acagggcagc aggcacaaca gacaagccca
1021 caagtgacca ccctgagctc ctgcctgcca gccctggaga ccatgaaaca gatggccagg
1081 attatcccat aggtcagcca gacctcagtc caacaggtct gcatcgctgc tgccctccaa
1141 taccagtccg gatggggaca gggccggccc acattaccat ttgctgccat ccggccaaca
1201 gtcccagaag cccctccctc aaggctgggc cacatgtgtg gaccctgaga gccccccatg
1261 tctgagtagg ggcaccagga agtgggctgg ccctgtgcac tgtcactgcc cctgtggtcc
1321 ctggcctgcc tggccctgac acctgggcct ctcctgggtc atttccaaga cagaagacat
1381 tcccaggaca gctggagctg ggagtccatc atcctgcctg gccatcctga gtcctgcgcc
1441 tttccaaacc tcacccggga agccaacaga ggaatcacct cccacaggca gagacaaaga
1501 ccttccagaa atctctgtct ctctccccag tgggcaccct cttccagggc agtcctcagt
1561 gatatcacag tgggaaccca catctggatc gggactgccc ccagaacaca agatggccca
1621 cagggacagc cccacagccc agcccttccc agacccctaa aaggcgtccc accccctgca
1681 tctgccccag ggctcaaact ccaggaggac tgactcctgc acaccctcct gccagacatc
1741 acctcagccc ctcctggaag ggacaggagc gcgcaagggt gagtcagacc ctcctgccct
1801 cgatggcagg cggagaagat tcagaaaggt ctgagatccc caggacgcag caccactgtc
1861 aatgggggcc ccagacgcct ggaccagggc ctgcgtggga aaggcctctg ggcacactca
1921 ggggcttttt gtgaagggtc ctcctactgt gtgactacag taactaccac agtgatgaac
1981 ccagcagcaa aaactgaccg gactcccaag gtttatgcac acttctcgct cagagctctc
2041 caggatcaga agagccgggc ccaagggttt ctgcccagac cctcggcctc tagggacatc
2101 ttggccatga cagcccatgg gctgtgcccc acacatcgtc tgccttcaaa caagggcttc
2161 agagggctct gaggtgacct cactgatgac cacaggtgcc ctggcccctt ccccgccagc
2221 tgcaccagac cccgtcctga cagatgcccc gattccaaca gccaattcct ggggccagga
2281 atcgctgtag acaccagcct ccttccaaca cctcttgcca attgcctgga ttcccatccc
2341 ggttggaatc aagaggacag catcccccag gctcccaaca ggcaggactc ccacaccctc
2401 ctctgagagg ccgctgtgtt ccgtagggcc aggctgcaga cagtccccct cacctgccac
2461 tagacaaatg cctgctgtag atgtccccac ctggaaaaga ccactcatgg agcccccagc
2521 cccaggtaca gccatagaga gagtctctga ggcccctaag aagtagccat gcccagttct
2581 gccgggaccc tcggccaggc tgacaggagt ggacgctgga gctgggccca cactgggcca
2641 cataggagct caccagtgag ggcaggagag cacatgccgg ggagcaccca gcctcctgct
2701 gaccagaggc ccgtcccaga gcccaggagg ctgcagaggc ctctccaggg ggacactgtg
2761 catgtctggt ccctgagcag ccccccatgt ccccagtcct ggggggcccc ctggcacagc
2821 tgtctggacc ctctctattc cctgggaagc tcctcctgac agccccgcct ccagttccag
2881 gtgtggttat tgtcaggggg tgtcagactg tggtggatac agctatggtt accacagtgg
2941 tgctgcccat agcagcaacc aggccaagta gacaggcccc tgtgcgcagc cccaggcatc
3001 cacttcacct gcttctcctg gggctctcaa ggctgctgtt ttctgcactc tcccctctgt
3061 ggggagggtt ccctcagtgg gaggatctgt tctcaacatc ccagggcctc attcctgcaa
3121 ggaaggccaa tgatgggcaa cctcacatgc cgcggctaag atagggtggg cagctggcgg
3181 ggacaggaca tcctgctggg gtatctgtca ctgtgcctag tggggcactg gctcccaaac
3241 aacgcagtcc tcgccaaaat ccccacggcc tcccccgcta ggggctggcc tgatctcctg
3301 cagtcctagg aggctgctga cctccagaat ggctccgtcc ccagttccag ggcgagagca
3361 gatcccaggc cggctgcaga ctgggaggcc accccctcct tcccagggtt cactgcaggt
3421 gaccagggca ggaaatggcc tgaacacagg gataaccggg ccatccccca acagagtcca
3481 ccccctcctg ctctgtaccc cgcaccccca aggccagccc atgacatccg acaaccccac
3541 accagagtca ctgcccggtg ctgccctagg gaggacccct cagcccccac cctgtctaga
3601 ggactgggga ggacaggaca cgccctctcc ttatggttcc cccacctggc tctggctggg
3661 acccttgggg tgtggacaga aaggacgctt gcctgattgg cccccaggag cccagaactt
3721 ctctccaggg accccagccc gagcaccccc ttacccagga cccagccctg cccctcctcc
3781 catctgctct cctctcatca ccccatggga atccagaatc cccaggaagc catcaggaag
3841 ggctgaggga ggaagtgggg ccacgtgcac caccaggcag gaggctccgt ctttgtgaac
3901 ccagggaggt gccagcctcc tagagggtat ggtccaccct gcctatggct cccacagtgg
3961 caggctgcag ggaaggacca gggacggtgt gggggagggc tcagggccgc gcgggtgctc
4021 catcttggat gagcccatct ctctcaccca cggactcacc cacctcctct ccaccctggt
4081 cacacgtcgt ccacaccatc ctaagtccca cctacaccag agccggcaca gccagtgcag
4141 acagaggctg gggtgcaggg gggccgccag ggcagctttg gggagggagg aatggaggaa
4201 ggggagttca gtgaagaggc ccccctcccc tgggtccagg atcctcctct gggacccccg
4261 gatcccatcc cctccaggct ctgggaggag aagcaggatg ggagaatctg tgcgggaccc
4321 tctcacagtg gaatacctcc acagcggctc aggcaagacc caaaagcccc tcagtgagcc
4381 ctccactgca gtcctgggcc tgggtagcag cccctcccac agaggatgaa cccagcaccc
4441 cgaggatgtc ctgccagggg gagctcagag ccatgaagga gcaggatatg ggacccccga
4501 tacaggcaca gacctcagct ccattcagga ctgccacgtc ctgccctggg aggaacccct
4561 ttctctagtc cctgcaggcc aggaggcagc tgactcctga cttggacgcc tattccagac
4621 accagacaga ggggcaggcc ccccagaacc agggatgagg acgccccgtc aaggccagaa
4681 aagaccaagt tgtgctgagc ccagcaaggg aaggtcccca aacaaaccag gaacgtttct
4741 gaaggtgtct gtgtcacagt ggagtatagc agctcgtccc acagtgacac tcgccaggcc
4801 agaaacccca tcccaagtca gcggaatgca gagagagcag ggaggacatg tttaggatct
4861 gaggccgcac ctgacaccca ggccagcaga cgtctcctgt ccatggcacc ctgccatgtc
4921 ctgcatttct ggaagaacaa gggcaggctg aagggggtcc aggaccagga gatgggtccc
4981 ctctacccag agaaggagcc aggcaggaca caagccccct ccccattgag gctgacctgc
5041 ccagagggtc ctgggcccac cccacacacc ggggcggaat gtgtgcaggc ctcggtctct
5101 gtgggtgttc cgctagctgg ggctcacagt gctcacccca cacctaaaac gagccacagc
5161 ctcagagccc ctgaaggaga ccccgcccac aagcccagcc cccacccagg aggccccaga
5221 gcacagggcg ccccgtcgga ttctgaacag ccccgagtca cagtgggtat aactggaact
5281 accactgtga gaaaagcttc gtccaaaacg gtctcctggc cacagtcgga ggccccgcca
5341 gagaggggag cagccacccc aaacccatgt tctgccggct cccatgaccc cgtgcacctg
5401 gagccccaca gtgtccccac tggatgggag gacaagggcc gggggctccg gcgggtcggg
5461 gcaggggctt gatggcttcc ttctgccgtg gctccagtgc ccctggctgg agttgaccct
5521 tctgacaagt gtcctcagag agtcagggat cagtggcacc tcccaacatc aaccccacgc
5581 agcccaggca caaaccccac atccagggcc aactccagga acagagacac cccaataccc
5641 tgggggaccc caaccctgat gactcccgtc ccatctctgt ccctcacttg gggcctgctg
5701 cggggcgagc acttgggagc aaactcaggc ttaggggaca ccactgtggg cctgacctcg
5761 agcaggccac agacccttcc ctcctgccct ggtgcagcac agactttggg gtctgggcag
5821 ggaggaactt ctggcaggtc accaagcaca gagcccccag gctgaggtgg ccccaggggg
5881 aaccccagca ggtggcccac tacccttcct cccagctgga ccccatgtct tccccaagat
5941 aggggtgcca tccaaggcag gtcctccatg gagccccctt caggctcctc tccagacccc
6001 actgggcctc agtccccact ctaggaatgc agccaccacg ggcacaccag gcagcccagg
6061 cccagccacc ctgcagtgcc caagcccaca ccctggagga gagcagggtg cgtctgggag
6121 gggctgggct ccccaccccc acccccacct gcacacccca cccacccttg cccgggcccc
6181 ctgcaggagg gtcagagccc ccatgggata tggacttagg gtctcactca cgcacctccc
6241 ctcctgggag aaggggtctc atgcccagat ccccccagca gcgctggtca caggtagagg
6301 cagtggcccc agggccaccc tgacctggcc cctcaggcat cctctagccc tggctgccct
6361 gctgtccctg ggaggcctgg gctccaccag accacaggtc tagggcaccg cccacactgg
6421 ggccgcccac acacagctca caggaagaag ataagctcca gacccccagg cccgggacct
6481 gccttgctgc tacgacttcc tgccccagac ctcgttgccc tcccccgtcc acttacacac
6541 aggccaggaa gactgttccc acacagacca accccagacg gggaccacct ggcactcagg
6601 tcactgccat ttccttctcc attcacttcc aatgcctctg tgcttcctcc tcctccttcc
6661 ttcgggggag caccctgtgc agctcctccc tgcagtccac accctgggga gacccgaccc
6721 tgcagcccac accctgggga gacctgaccc tcctccagcc ctttctcccc cgctgctctt
6781 gccacccacc aagacagccc tggggtcctg tccctacagc ccccacccag ttctctacct
6841 agacccgtct tcctccctct aaacacctct cccaggccaa ccctacacct gcaggccctc
6901 ccctccactg ccaaagaccc tcagtttctc ctgcctgtgc ccacccccgt gctcctcctg
6961 cccacagctc gagctcttcc tctcctaggg cccctgaggg atggcattga ccgtgccctc
7021 gcacccacac actgcccatg ccctcacatt cctcctggcc actccagccc cactcccctc
7081 tcaggcctgg ctctggtatt tctgggacaa agccttaccc aagtctttcc catgcaggcc
7141 tgggccctta ccctcactgc ccggttacag ggcagcctcc tgtgcacaga agcagggagc
7201 tcagcccttc cacaggcaga aggcactgaa agaaatcggc ctccagcgcc ttgacacacg
7261 tctgcctgtg tctctcactg cccgcacctg cagggaggct cggcactccc tctaaagacg
7321 agggatccag gcagcagcat cacaggagaa tgcagggcta ccagacatcc cagtcctctc
7381 acaggcctct cctgggaaga gacctgaaga cgcccagtca acggagtcta acaccaaacc
7441 tccctggagg ccgatgggta gtaacggagt cattgccaga cctggaggca ggggagcagt
7501 gagcccgagc ccacaccata gggccagagg acagccactg acatcccaag ccactcactg
7561 gtggtcccac aacaccccat ggaaagagga cagacccaca gtcccacctg gaccagggca
7621 gagactgctg agacccagca ccagaaccaa ccaagaaaca ccaggcaaca gcatcagagg
7681 gggctctggc agaacagagg aggggaggtc tccttcacca gcaggcgctt cccttgaccg
7741 aagacaggat ccatgcaact cccccaggac aaaggaggag ccccttgttc agcactgggc
7801 tcagagtcct ctccaagaca cccagagttt cagacaaaaa ccccctggaa tgcacagtct
7861 cagcaggaga gccagccaga gccagcaaga tggggctcag tgacacccgc agggacagga
7921 ggattttgtg ggggctcgtg tcactgtgag gatattgtac taatggtgta tgctataccc
7981 acagtgacac agccccattc ccaaagccct actgcaaacg cattccactt ctggggctga
8041 ggggctgggg gagcgtctgg gaaatagggc tcaggggtgt ccatcaatgc ccaaaacgca
8101 ccagactccc ctccatacat cacacccacc agccagcgag cagagtaaac agaaaatgag
8161 aagcaagctg gggaagcttg cacaggcccc aaggaaagag ctttggcggg tgtgtaagag
8221 gggatgcggg cagagcctga gcagggcctt ttgctgtttc tgctttcctg tgcagagagt
8281 tccataaact ggtgttcgag atcaatggct gggagtgagc ccaggaggac agcgtgggaa
8341 gagcacaggg aaggaggagc agccgctatc ctacactgtc atctttcgaa agtttgcctt
8401 gtgcccacac tgctgcatca tgggatgctt aacagctgat gtagacacag ctaaagagag
8461 aatcagtgag atggatttgc agcacagatc tgaataaatt ctccagaatg tggagcagca
8521 cagaagcaag cacacagaaa gtgcctgatg caaggacaaa gttcagtggg caccttcagg
8581 cattgctgct gggcacagac actctgaaaa gccctggcag gaactccctg tgacaaagca
8641 gaaccctcag gcaatgccag ccccagagcc ctccctgaga gcctcatggg caaagatgtg
8701 cacaacaggt gtttctcata gccccaaact gagagcaaag caaacgtcca tctgaaggag
8761 aacaggcaaa taaacgatgg caggttcatg aaatgcaaac ccagacagcc acaagcacaa
8821 aagtacaggg ttataagcga ctctggttga gttcatgaca atgctgagta attggagtaa
8881 caaagtaaac tccaaaaaat actttcaatg tgatttcttc taaataaaat ttacaccctg
8941 caaaatgaac tgtcttctta agggatacat ttcccagtta gaaaaccata aagaaaacca
9001 agaaaaggat gatcacataa acacagtggt ggttacttct gctggggaag gaagagggta
9061 tgaactgaga tacacagggt gggcaagtct cctaacaaga acagaacgaa tacattacag
9121 taccttgaaa acagcagtta aacttctaaa ttgcaagaag aggaaaatgg acacagttgt
9181 gtttagaaaa ttctcagtcc agcactgttc ataatagcaa agacattaac ccaggtcgga
9241 taaataagcg atgacacagg caattgcaca atgatacaga catatattta gtatatgaga
9301 catcgatgat gtatccccaa ataaacgact ttaaagagat aaagggctga tgtgtggtgg
9361 cattcacctc cctgggatcc ccggacaggt tgcaggctca ctgtgcagca gggcaggcgg
9421 gtacctgctg gcagttcctg gggcctgatg tggagcaagc gcagggccat atatcccgga
9481 gacggcacag tcagtgaatt ccagagagaa gcaactcagc cacactcccc aggcagagcc
9541 cgagagggac gcccacgcac agggaggcag agcccagcac ctccgcagcc agcaccacct
9601 gtgcacgggc caccaccttg caggcacaga gtgggtgctg agaggagggg cagggacacc
9661 aggcaggtga gcacccagag aaaactgcag acgcctcaca catccacctc agcctcccct
9721 gacctggacc tcactgcctg ggcctcactt aacctgggct tcacctgacc ttggcctcac
9781 ctgacttgga cctgcctgtc ccaagcttta cctgacctgg gcctcaactc acctgaacgt
9841 ctcctgacct gggtttaacc tgtcctggaa ctcacctggc cttggcttcc cctgacctgg
9901 acctcatctg gcctgggctt cacctggcct gggcctcacc tgacctggac ctcatctggc
9961 ctggacctca cctggcctgg acttcacctg gcctgggctt cacctgacct ggacctcacc
10021 tggcctcggg cctcacctgc acctgctcca ggtcttgctg gagcctgagt agcactgagg
10081 gtgcagaagc tcatccaggg ttggggaatg actctagaag tctcccacat ctgacctttc
10141 tgggtggagg cagctggtgg ccctgggaat ataaaaatct ccagaatgat gactctgtga
10201 tttgtgggca acttatgaac ccgaaaggac atggccatgg ggtgggtagg gacataggga
10261 cagatgccag cctgaggtgg agcctcagga cacaggtggg cacggacact atccacataa
10321 gcgagggata gacccgagtg tccccacagc agacctgaga gcgctgggcc cacagcctcc
10381 cctcagagcc ctgctgcctc ctccggtcag ccctggacat cccaggtttc cccaggcctg
10441 ccggtaggtt tagaatgagg tctgtgtcac tgtggtatta cgatattttg actggttatt
10501 ataaccacag tgtcacagag tccatcaaaa acccatgcct ggaagcttcc cgccacagcc
10561 ctccccatgg ggccctgctg cctcctcagg tcagccccgg acatcccggg tttccccagg
10621 ctgggcggta ggtttggggt gaggtctgtg tcactgtggt attactatgg ttcggggagt
10681 tattataacc acagtgtcac agagtccatc aaaaacccat ccctgggagc ctcccgccac
10741 agccctccct gcagggaccg tacgtgccat gttaggattt tgatcgagga gacagcacca
10801 tgggtatggt ggctaccaca gcagtgcagc ctgtgaccca aacccacagg gcagcaggca
10861 cgatggacag gcccgtgact gaccacgctg ggctccagcc tgccagccct ggagatcatg
10921 aaacagatgg ccaaggtcac cctacaggtc atccagatct ggctccgagg ggtctgcatc
10981 gctgctgccc tcccaacgcc agtccaaatg ggacagggac ggcctcacag caccatctgc
11041 tgccatcagg ccagcgatcc cagaagcccc tccctcaagg ctgggccaca tgtgtggaca
11101 tgagagccct catgtctgag taggggcaca ggagggaggg gctggccctg tgcactgtcc
11161 ctgcccctgt ggtccctggc ctgcctggcc ctgacactga gcctctcctg ggtcatttcc
11221 aagacagaag acattcctgg ggacagccgg agctgggcgt cgctcatcct gcccggccgt
11281 cctgagtcct gctcatttcc agacctcacc ggggaagcca acagaggact cgcctcccac
11341 attcagagac aaagaacctt ccagaaatcc ctgcctctct ccccagtgga caccctcttc
11401 caggacagtc ctcagtggca tcacagcggc ctgagatccc caggacgcag caccgctgtc
11461 aataggggcc ccaaatgcct ggaccagggc ctgcgtggga aaggtctctg gccacactcg
11521 ggctttttgt gaagggccct cctgctgtgt gactacagta actaccatag tgatgaaccc
11581 agtggcaaaa actggctgga aacccagggg ctgtgtgcac gcctcagctt ggagctctcc
11641 aggagcacaa gagccgggcc caaggatttg tgcccagacc ctcagcctct agggacacct
11701 gggccatctc agcctgggct ggtgccctgc acaccatctt cctccaaata ggggcttcag
11761 agggctctga ggtgacctca ctcatgacca caggtgacct ggcccttccc tgccagctat
11821 accagaccct gtcttgacag atgccccgat tccaacagcc aattcctggg accctgaata
11881 gctgtagaca ccagcctcat tccagtacct cctgccaatt gcctggattc ccatcctggc
11941 tggaatcaag aaggcagcat ccgccaggct cccaacaggc aggactcccg cacaccctcc
12001 tctgagaggc cgctgtgttc cgcagggcca ggccctggac agttcccctc acctgccact
12061 agagaaacac ctgccattgt cgtccccacc tggaaaagac cactcgtgga gcccccagcc
12121 ccaggtacag ctgtagagag agtcctcgag gcccctaaga aggagccatg cccagttctg
12181 ccgggaccct cggccaggcc gacaggagtg gacgctggag ctggcccaca ctgggcatag
12241 gagctcacca gtgagggcag gagagcacat gccggggagc acccagcctc ctgctgacca
12301 gaggcctgcc ccagagccca ggaggctgca gaggcctctc cagggagaca ctgtgcatgt
12361 ctggtaccta agcagccccc cacgtcccca gtcctggggg cccctggctc agctgtctgg
12421 accctccctg ttccctggga agctcctcct gacagccccg cctccagttc caggtgtggt
12481 tattgtcagg cgatgtcaga ctgtggtgga tatagtggct acgattacca cagtggtgcc
12541 gcccatagca gcaaccaggc caagtagaca ggcccctgct gcgcagcccc aggcatccac
12601 ttcacctgct tctcctgggg ctctcaaggc tgctgtctgt cctctggccc tctgtgggga
12661 gggttccctc agtgggaggt ctgtgctcca gggcagggat gattgagata gaaatcaaag
12721 gctggcaggg aaaggcagct tcccgccctg agaggtgcag gcagcaccac ggagccacgg
12781 agtcacagag ccacggagcc cccattgtgg gcatttgaga gtgctgtgcc cccggcagcc
12841 cagccctgat ggggaagcct gtcccatccc acagcccggg tcccacgggc agcgggcaca
12901 gaagctgcca ggttgtcctc tatgatcctc atccctccag cagcatcccc tccacagtgg
12961 ggaaactgag gcttggagca ccacccggcc ccctggaaat gaggctgtga gcccagacag
13021 tgggcccaga gcactgtgag taccccggca gtacctggct gcagggatca gccagagatg
13081 ccaaaccctg agtgaccagc ctacaggagg atccggcccc acccaggcca ctcgattaat
13141 gctcaacccc ctgccctgga gacctcttcc agtaccacca gcagctcagc ttctcagggc
13201 ctcatccctg caagaaggtc aagggctggg cctgccagaa acacagcacc ctccctagcc
13261 ctggctaaga cagggtgggc agacggctgt ggacgggaca tattgctggg gcatttctca
13321 ctgtcacttc tgggtggtag ctctgacaaa aacgcagacc ctgccaaaat ccccactgcc
13381 tcccgctagg ctggcctgga atcctgctgt cctaggaggc tgctgacctc caggatggct
13441 ccgtccccag ttccagggcg agagcagatc ccaggcaggc tgtaggctgg gaggccaccc
13501 ctgcccttgc cggggttgaa tgcaggtgcc caaggcagga aatggcatga gcacagggat
13561 gaccgggaca tgccccacca gagtgcgccc cttcctgctc tgcaccctgc accccccagg
13621 ccagcccacg acgtccaaca actgggcctg ggtggcagcc ccacccagac aggacagacc
13681 cagcaccctg aggaggtcct gccaggggga gctaagagcc atgaaggagc aagatatggg
13741 gcccccgata caggcacaga tgtcagctcc atccaggacc acccagccca caccctgaga
13801 ggaacgtctg tctccagcct ctgcaggtcg ggaggcagct gacccctgac ttggacccct
13861 attccagaca ccagacagag gcgcaggccc cccagaacca gggttgaggg acgccccgtc
13921 aaagccagac aaaaccaagg ggtgttgagc ccagcaaggg aaggccccca aacagaccag
13981 gaggtttctg aaggtgtctg tgtcacagtg gggtatagca gcagctggta ccacagtgac
14041 actcacccag ccagaaaccc cattccaagt cagcggaagc agagagagca gggaggacac
14101 gtttaggatc tgagactgca cctgacaccc aggccagcag acgtctcccc tccagggcac
14161 cccaccctgt cctgcatttc tgcaagatca ggggcggcct gagggggggt ctagggtgag
14221 gagatgggtc ccctgtacac caaggaggag ttaggcaggt cccgagcact ctccccattg
14281 aggctgacct gcccagagag tcctgggccc accccacaca ccggggcgga atgtgtccag
14341 gcctcggtct ctgtgggtgt tccgctagct ggggctcaca gtgctcaccc cacacctaaa
14401 atgagccaca gcctccggag cccccgcaga gaccccgccc acaagcccag cccccaccca
14461 ggaggcccca gagctcaggg cgccccgtcg gattccgaac agccccgagt cacagcgggt
14521 ataaccggaa ccaccactgt cagaatagct acgtcaaaaa ctgtccagtg gccactgccg
14581 gagcccccgc cagagagggc agcagccact ctgatcccat gtcctgccgg ctcccatgac
14641 ccccagcacg cggagcccac agtgtcccca ctggatggga ggacaagagc tggggattcc
14701 ggcgggtcgg ggcaggggct tgatcgcatc cttctgccgt ggctccagtg cccctggctg
14761 gagttgaccc ttctgacaag tgtcctcaga gagacaggca tcaccggcgc ctcccaacat
14821 caaccccagg cagcacaggc acaaacccca catccagagc caactccagg agcagagaca
14881 ccccaatacc ctgggggacc ccgaccctga tgacttccca ctggaattc
//GenBank-Updates@genbank.bio.net (02/14/91)
LOCUS HUMIGHDLA 14929 bp ds-DNA PRI 14-FEB-1991
DEFINITION Human Ig germline H-chain D-region genes, partial cds.
ACCESSION M37277
KEYWORDS diversity exon; germline; immunoglobin heavy chain.
SOURCE Human DNA, clone HUD-3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 14929)
AUTHORS Ichihara,Y., Matsuoka,H. and Kurosawa,Y.
TITLE Organization of human immunoglobulin heavy chain diversity gene
loci
JOURNAL EMBO J. 7, 4141-4150 (1988)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS 804..834
/product="Ig H-chain"
/gene="Ig H-chain DXP4"
/codon_start=804
/partial
CDS 1952..1967
/product="Ig H-chain"
/gene="Ig H-chain DA4"
/codon_start=1953
/partial
CDS 2913..2932
/product="Ig H-chain"
/gene="Ig H-chain DK4"
/codon_start=2913
/partial
CDS 4762..4779
/product="Ig H-chain"
/gene="Ig H-chain DN4"
/codon_start=4762
/partial
CDS 5266..5282
/product="Ig H-chain"
/gene="Ig H-chain DM1"
/codon_start=5266
/partial
CDS 7949..7979
/product="Ig H-chain"
/gene="Ig H-chain DLR1"
/codon_start=7950
/partial
CDS 10475..10505
/product="Ig H-chain"
/gene="Ig H-chain DXP1"
/codon_start=10476
/partial
CDS 10659..10689
/product="Ig H-chain"
/gene="Ig H-chain DXP'1"
/codon_start=10660
/partial
CDS 11550..11565
/product="Ig H-chain"
/gene="Ig H-chain DA1"
/codon_start=11551
/partial
CDS 12506..12528
/product="Ig H-chain"
/gene="Ig H-chain DK1"
/codon_start=12506
/partial
CDS 14011..14031
/product="Ig H-chain"
/gene="Ig H-chain DN1"
/codon_start=14011
/partial
CDS 14518..14534
/product="Ig H-chain"
/gene="Ig H-chain DM2"
/codon_start=14518
/partial
BASE COUNT 3308 a 4994 c 4069 g 2558 t
ORIGIN
1 gaattcatgc cgccatctgg caggcacaga gcatgggctg ggaggagggg cagggacacc
61 aggcaggttg gcaccaactg aaaattacag aagtctcata catctacctc agccttgcct
121 gacctgggcc tcacctgacc tggacctcac ctggcctgga cctcacctgg cctagacctc
181 acctctgggc ttcacctgag ctcggcctca cctgacttgg accttgcctg tcctgagctc
241 acatgatctg ggcctcacct gacctggttt cacctgacct gggcttcacc tgacctgggc
301 ctcatctgac ctgggcctca ctggcctgga cctcacctgg cctgggcttc acctggcctc
361 aggcctcatc tgcacctgct ccaggtcttg ctggaacctc agtagcactg aggctgcagg
421 ggctcatcca gggttgcaga atgactctag aacctcccac atctcagctt tctgggtgga
481 ggcactggtg gcccagggaa tataaaaagc ctgaatgatg cctgcgtgat ttgggggcaa
541 tttataaacc caaaatggac atggccatgc agcgggtagg gacaatacag acagatatca
601 gcctgaaatg gagcctcagg gcacagtggg cacggacact gtccacctaa gccaggggca
661 gacccgagtg tccccgcagt agacctgaga gcgctgggcc cacagcctcc cctcggtgcc
721 ctgctacctc ctcaggtcag ccctggacat cccgggtttc cccaggctgg cggtaggttt
781 ggggtgaggt ctgtgtcact gtggtattac gatttttgga gtggttatta tacccacagt
841 gtcacagagt ccatcaaaaa cccatccctg ggaaccttct gccacagccc tcctgtgggg
901 caccgccgcg tgccatgtta ggattttgac tgaggacaca gcaccatggg tatggtgcta
961 ccgcagcagt gcagcctgtg acccaaacac acagggcagc aggcacaaca gacaagccca
1021 caagtgacca ccctgagctc ctgcctgcca gccctggaga ccatgaaaca gatggccagg
1081 attatcccat aggtcagcca gacctcagtc caacaggtct gcatcgctgc tgccctccaa
1141 taccagtccg gatggggaca gggccggccc acattaccat ttgctgccat ccggccaaca
1201 gtcccagaag cccctccctc aaggctgggc cacatgtgtg gaccctgaga gccccccatg
1261 tctgagtagg ggcaccagga agtgggctgg ccctgtgcac tgtcactgcc cctgtggtcc
1321 ctggcctgcc tggccctgac acctgggcct ctcctgggtc atttccaaga cagaagacat
1381 tcccaggaca gctggagctg ggagtccatc atcctgcctg gccatcctga gtcctgcgcc
1441 tttccaaacc tcacccggga agccaacaga ggaatcacct cccacaggca gagacaaaga
1501 ccttccagaa atctctgtct ctctccccag tgggcaccct cttccagggc agtcctcagt
1561 gatatcacag tgggaaccca catctggatc gggactgccc ccagaacaca agatggccca
1621 cagggacagc cccacagccc agcccttccc agacccctaa aaggcgtccc accccctgca
1681 tctgccccag ggctcaaact ccaggaggac tgactcctgc acaccctcct gccagacatc
1741 acctcagccc ctcctggaag ggacaggagc gcgcaagggt gagtcagacc ctcctgccct
1801 cgatggcagg cggagaagat tcagaaaggt ctgagatccc caggacgcag caccactgtc
1861 aatgggggcc ccagacgcct ggaccagggc ctgcgtggga aaggcctctg ggcacactca
1921 ggggcttttt gtgaagggtc ctcctactgt gtgactacag taactaccac agtgatgaac
1981 ccagcagcaa aaactgaccg gactcccaag gtttatgcac acttctcgct cagagctctc
2041 caggatcaga agagccgggc ccaagggttt ctgcccagac cctcggcctc tagggacatc
2101 ttggccatga cagcccatgg gctgtgcccc acacatcgtc tgccttcaaa caagggcttc
2161 agagggctct gaggtgacct cactgatgac cacaggtgcc ctggcccctt ccccgccagc
2221 tgcaccagac cccgtcctga cagatgcccc gattccaaca gccaattcct ggggccagga
2281 atcgctgtag acaccagcct ccttccaaca cctcttgcca attgcctgga ttcccatccc
2341 ggttggaatc aagaggacag catcccccag gctcccaaca ggcaggactc ccacaccctc
2401 ctctgagagg ccgctgtgtt ccgtagggcc aggctgcaga cagtccccct cacctgccac
2461 tagacaaatg cctgctgtag atgtccccac ctggaaaaga ccactcatgg agcccccagc
2521 cccaggtaca gccatagaga gagtctctga ggcccctaag aagtagccat gcccagttct
2581 gccgggaccc tcggccaggc tgacaggagt ggacgctgga gctgggccca cactgggcca
2641 cataggagct caccagtgag ggcaggagag cacatgccgg ggagcaccca gcctcctgct
2701 gaccagaggc ccgtcccaga gcccaggagg ctgcagaggc ctctccaggg ggacactgtg
2761 catgtctggt ccctgagcag ccccccatgt ccccagtcct ggggggcccc ctggcacagc
2821 tgtctggacc ctctctattc cctgggaagc tcctcctgac agccccgcct ccagttccag
2881 gtgtggttat tgtcaggggg tgtcagactg tggtggatac agctatggtt accacagtgg
2941 tgctgcccat agcagcaacc aggccaagta gacaggcccc tgtgcgcagc cccaggcatc
3001 cacttcacct gcttctcctg gggctctcaa ggctgctgtt ttctgcactc tcccctctgt
3061 ggggagggtt ccctcagtgg gaggatctgt tctcaacatc ccagggcctc attcctgcaa
3121 ggaaggccaa tgatgggcaa cctcacatgc cgcggctaag atagggtggg cagctggcgg
3181 ggacaggaca tcctgctggg gtatctgtca ctgtgcctag tggggcactg gctcccaaac
3241 aacgcagtcc tcgccaaaat ccccacggcc tcccccgcta ggggctggcc tgatctcctg
3301 cagtcctagg aggctgctga cctccagaat ggctccgtcc ccagttccag ggcgagagca
3361 gatcccaggc cggctgcaga ctgggaggcc accccctcct tcccagggtt cactgcaggt
3421 gaccagggca ggaaatggcc tgaacacagg gataaccggg ccatccccca acagagtcca
3481 ccccctcctg ctctgtaccc cgcaccccca aggccagccc atgacatccg acaaccccac
3541 accagagtca ctgcccggtg ctgccctagg gaggacccct cagcccccac cctgtctaga
3601 ggactgggga ggacaggaca cgccctctcc ttatggttcc cccacctggc tctggctggg
3661 acccttgggg tgtggacaga aaggacgctt gcctgattgg cccccaggag cccagaactt
3721 ctctccaggg accccagccc gagcaccccc ttacccagga cccagccctg cccctcctcc
3781 catctgctct cctctcatca ccccatggga atccagaatc cccaggaagc catcaggaag
3841 ggctgaggga ggaagtgggg ccacgtgcac caccaggcag gaggctccgt ctttgtgaac
3901 ccagggaggt gccagcctcc tagagggtat ggtccaccct gcctatggct cccacagtgg
3961 caggctgcag ggaaggacca gggacggtgt gggggagggc tcagggccgc gcgggtgctc
4021 catcttggat gagcccatct ctctcaccca cggactcacc cacctcctct ccaccctggt
4081 cacacgtcgt ccacaccatc ctaagtccca cctacaccag agccggcaca gccagtgcag
4141 acagaggctg gggtgcaggg gggccgccag ggcagctttg gggagggagg aatggaggaa
4201 ggggagttca gtgaagaggc ccccctcccc tgggtccagg atcctcctct gggacccccg
4261 gatcccatcc cctccaggct ctgggaggag aagcaggatg ggagaatctg tgcgggaccc
4321 tctcacagtg gaatacctcc acagcggctc aggcaagacc caaaagcccc tcagtgagcc
4381 ctccactgca gtcctgggcc tgggtagcag cccctcccac agaggatgaa cccagcaccc
4441 cgaggatgtc ctgccagggg gagctcagag ccatgaagga gcaggatatg ggacccccga
4501 tacaggcaca gacctcagct ccattcagga ctgccacgtc ctgccctggg aggaacccct
4561 ttctctagtc cctgcaggcc aggaggcagc tgactcctga cttggacgcc tattccagac
4621 accagacaga ggggcaggcc ccccagaacc agggatgagg acgccccgtc aaggccagaa
4681 aagaccaagt tgtgctgagc ccagcaaggg aaggtcccca aacaaaccag gaacgtttct
4741 gaaggtgtct gtgtcacagt ggagtatagc agctcgtccc acagtgacac tcgccaggcc
4801 agaaacccca tcccaagtca gcggaatgca gagagagcag ggaggacatg tttaggatct
4861 gaggccgcac ctgacaccca ggccagcaga cgtctcctgt ccatggcacc ctgccatgtc
4921 ctgcatttct ggaagaacaa gggcaggctg aagggggtcc aggaccagga gatgggtccc
4981 ctctacccag agaaggagcc aggcaggaca caagccccct ccccattgag gctgacctgc
5041 ccagagggtc ctgggcccac cccacacacc ggggcggaat gtgtgcaggc ctcggtctct
5101 gtgggtgttc cgctagctgg ggctcacagt gctcacccca cacctaaaac gagccacagc
5161 ctcagagccc ctgaaggaga ccccgcccac aagcccagcc cccacccagg aggccccaga
5221 gcacagggcg ccccgtcgga ttctgaacag ccccgagtca cagtgggtat aactggaact
5281 accactgtga gaaaagcttc gtccaaaacg gtctcctggc cacagtcgga ggccccgcca
5341 gagaggggag cagccacccc aaacccatgt tctgccggct cccatgaccc cgtgcacctg
5401 gagccccaca gtgtccccac tggatgggag gacaagggcc gggggctccg gcgggtcggg
5461 gcaggggctt gatggcttcc ttctgccgtg gctccagtgc ccctggctgg agttgaccct
5521 tctgacaagt gtcctcagag agtcagggat cagtggcacc tcccaacatc aaccccacgc
5581 agcccaggca caaaccccac atccagggcc aactccagga acagagacac cccaataccc
5641 tgggggaccc caaccctgat gactcccgtc ccatctctgt ccctcacttg gggcctgctg
5701 cggggcgagc acttgggagc aaactcaggc ttaggggaca ccactgtggg cctgacctcg
5761 agcaggccac agacccttcc ctcctgccct ggtgcagcac agactttggg gtctgggcag
5821 ggaggaactt ctggcaggtc accaagcaca gagcccccag gctgaggtgg ccccaggggg
5881 aaccccagca ggtggcccac tacccttcct cccagctgga ccccatgtct tccccaagat
5941 aggggtgcca tccaaggcag gtcctccatg gagccccctt caggctcctc tccagacccc
6001 actgggcctc agtccccact ctaggaatgc agccaccacg ggcacaccag gcagcccagg
6061 cccagccacc ctgcagtgcc caagcccaca ccctggagga gagcagggtg cgtctgggag
6121 gggctgggct ccccaccccc acccccacct gcacacccca cccacccttg cccgggcccc
6181 ctgcaggagg gtcagagccc ccatgggata tggacttagg gtctcactca cgcacctccc
6241 ctcctgggag aaggggtctc atgcccagat ccccccagca gcgctggtca caggtagagg
6301 cagtggcccc agggccaccc tgacctggcc cctcaggcat cctctagccc tggctgccct
6361 gctgtccctg ggaggcctgg gctccaccag accacaggtc tagggcaccg cccacactgg
6421 ggccgcccac acacagctca caggaagaag ataagctcca gacccccagg cccgggacct
6481 gccttgctgc tacgacttcc tgccccagac ctcgttgccc tcccccgtcc acttacacac
6541 aggccaggaa gactgttccc acacagacca accccagacg gggaccacct ggcactcagg
6601 tcactgccat ttccttctcc attcacttcc aatgcctctg tgcttcctcc tcctccttcc
6661 ttcgggggag caccctgtgc agctcctccc tgcagtccac accctgggga gacccgaccc
6721 tgcagcccac accctgggga gacctgaccc tcctccagcc ctttctcccc cgctgctctt
6781 gccacccacc aagacagccc tggggtcctg tccctacagc ccccacccag ttctctacct
6841 agacccgtct tcctccctct aaacacctct cccaggccaa ccctacacct gcaggccctc
6901 ccctccactg ccaaagaccc tcagtttctc ctgcctgtgc ccacccccgt gctcctcctg
6961 cccacagctc gagctcttcc tctcctaggg cccctgaggg atggcattga ccgtgccctc
7021 gcacccacac actgcccatg ccctcacatt cctcctggcc actccagccc cactcccctc
7081 tcaggcctgg ctctggtatt tctgggacaa agccttaccc aagtctttcc catgcaggcc
7141 tgggccctta ccctcactgc ccggttacag ggcagcctcc tgtgcacaga agcagggagc
7201 tcagcccttc cacaggcaga aggcactgaa agaaatcggc ctccagcgcc ttgacacacg
7261 tctgcctgtg tctctcactg cccgcacctg cagggaggct cggcactccc tctaaagacg
7321 agggatccag gcagcagcat cacaggagaa tgcagggcta ccagacatcc cagtcctctc
7381 acaggcctct cctgggaaga gacctgaaga cgcccagtca acggagtcta acaccaaacc
7441 tccctggagg ccgatgggta gtaacggagt cattgccaga cctggaggca ggggagcagt
7501 gagcccgagc ccacaccata gggccagagg acagccactg acatcccaag ccactcactg
7561 gtggtcccac aacaccccat ggaaagagga cagacccaca gtcccacctg gaccagggca
7621 gagactgctg agacccagca ccagaaccaa ccaagaaaca ccaggcaaca gcatcagagg
7681 gggctctggc agaacagagg aggggaggtc tccttcacca gcaggcgctt cccttgaccg
7741 aagacaggat ccatgcaact cccccaggac aaaggaggag ccccttgttc agcactgggc
7801 tcagagtcct ctccaagaca cccagagttt cagacaaaaa ccccctggaa tgcacagtct
7861 cagcaggaga gccagccaga gccagcaaga tggggctcag tgacacccgc agggacagga
7921 ggattttgtg ggggctcgtg tcactgtgag gatattgtac taatggtgta tgctataccc
7981 acagtgacac agccccattc ccaaagccct actgcaaacg cattccactt ctggggctga
8041 ggggctgggg gagcgtctgg gaaatagggc tcaggggtgt ccatcaatgc ccaaaacgca
8101 ccagactccc ctccatacat cacacccacc agccagcgag cagagtaaac agaaaatgag
8161 aagcaagctg gggaagcttg cacaggcccc aaggaaagag ctttggcggg tgtgtaagag
8221 gggatgcggg cagagcctga gcagggcctt ttgctgtttc tgctttcctg tgcagagagt
8281 tccataaact ggtgttcgag atcaatggct gggagtgagc ccaggaggac agcgtgggaa
8341 gagcacaggg aaggaggagc agccgctatc ctacactgtc atctttcgaa agtttgcctt
8401 gtgcccacac tgctgcatca tgggatgctt aacagctgat gtagacacag ctaaagagag
8461 aatcagtgag atggatttgc agcacagatc tgaataaatt ctccagaatg tggagcagca
8521 cagaagcaag cacacagaaa gtgcctgatg caaggacaaa gttcagtggg caccttcagg
8581 cattgctgct gggcacagac actctgaaaa gccctggcag gaactccctg tgacaaagca
8641 gaaccctcag gcaatgccag ccccagagcc ctccctgaga gcctcatggg caaagatgtg
8701 cacaacaggt gtttctcata gccccaaact gagagcaaag caaacgtcca tctgaaggag
8761 aacaggcaaa taaacgatgg caggttcatg aaatgcaaac ccagacagcc acaagcacaa
8821 aagtacaggg ttataagcga ctctggttga gttcatgaca atgctgagta attggagtaa
8881 caaagtaaac tccaaaaaat actttcaatg tgatttcttc taaataaaat ttacaccctg
8941 caaaatgaac tgtcttctta agggatacat ttcccagtta gaaaaccata aagaaaacca
9001 agaaaaggat gatcacataa acacagtggt ggttacttct gctggggaag gaagagggta
9061 tgaactgaga tacacagggt gggcaagtct cctaacaaga acagaacgaa tacattacag
9121 taccttgaaa acagcagtta aacttctaaa ttgcaagaag aggaaaatgg acacagttgt
9181 gtttagaaaa ttctcagtcc agcactgttc ataatagcaa agacattaac ccaggtcgga
9241 taaataagcg atgacacagg caattgcaca atgatacaga catatattta gtatatgaga
9301 catcgatgat gtatccccaa ataaacgact ttaaagagat aaagggctga tgtgtggtgg
9361 cattcacctc cctgggatcc ccggacaggt tgcaggctca ctgtgcagca gggcaggcgg
9421 gtacctgctg gcagttcctg gggcctgatg tggagcaagc gcagggccat atatcccgga
9481 gacggcacag tcagtgaatt ccagagagaa gcaactcagc cacactcccc aggcagagcc
9541 cgagagggac gcccacgcac agggaggcag agcccagcac ctccgcagcc agcaccacct
9601 gtgcacgggc caccaccttg caggcacaga gtgggtgctg agaggagggg cagggacacc
9661 aggcaggtga gcacccagag aaaactgcag acgcctcaca catccacctc agcctcccct
9721 gacctggacc tcactgcctg ggcctcactt aacctgggct tcacctgacc ttggcctcac
9781 ctgacttgga cctgcctgtc ccaagcttta cctgacctgg gcctcaactc acctgaacgt
9841 ctcctgacct gggtttaacc tgtcctggaa ctcacctggc cttggcttcc cctgacctgg
9901 acctcatctg gcctgggctt cacctggcct gggcctcacc tgacctggac ctcatctggc
9961 ctggacctca cctggcctgg acttcacctg gcctgggctt cacctgacct ggacctcacc
10021 tggcctcggg cctcacctgc acctgctcca ggtcttgctg gagcctgagt agcactgagg
10081 gtgcagaagc tcatccaggg ttggggaatg actctagaag tctcccacat ctgacctttc
10141 tgggtggagg cagctggtgg ccctgggaat ataaaaatct ccagaatgat gactctgtga
10201 tttgtgggca acttatgaac ccgaaaggac atggccatgg ggtgggtagg gacataggga
10261 cagatgccag cctgaggtgg agcctcagga cacaggtggg cacggacact atccacataa
10321 gcgagggata gacccgagtg tccccacagc agacctgaga gcgctgggcc cacagcctcc
10381 cctcagagcc ctgctgcctc ctccggtcag ccctggacat cccaggtttc cccaggcctg
10441 ccggtaggtt tagaatgagg tctgtgtcac tgtggtatta cgatattttg actggttatt
10501 ataaccacag tgtcacagag tccatcaaaa acccatgcct ggaagcttcc cgccacagcc
10561 ctccccatgg ggccctgctg cctcctcagg tcagccccgg acatcccggg tttccccagg
10621 ctgggcggta ggtttggggt gaggtctgtg tcactgtggt attactatgg ttcggggagt
10681 tattataacc acagtgtcac agagtccatc aaaaacccat ccctgggagc ctcccgccac
10741 agccctccct gcagggaccg tacgtgccat gttaggattt tgatcgagga gacagcacca
10801 tgggtatggt ggctaccaca gcagtgcagc ctgtgaccca aacccacagg gcagcaggca
10861 cgatggacag gcccgtgact gaccacgctg ggctccagcc tgccagccct ggagatcatg
10921 aaacagatgg ccaaggtcac cctacaggtc atccagatct ggctccgagg ggtctgcatc
10981 gctgctgccc tcccaacgcc agtccaaatg ggacagggac ggcctcacag caccatctgc
11041 tgccatcagg ccagcgatcc cagaagcccc tccctcaagg ctgggccaca tgtgtggaca
11101 tgagagccct catgtctgag taggggcaca ggagggaggg gctggccctg tgcactgtcc
11161 ctgcccctgt ggtccctggc ctgcctggcc ctgacactga gcctctcctg ggtcatttcc
11221 aagacagaag acattcctgg ggacagccgg agctgggcgt cgctcatcct gcccggccgt
11281 cctgagtcct gctcatttcc agacctcacc ggggaagcca acagaggact cgcctcccac
11341 attcagagac aaagaacctt ccagaaatcc ctgcctctct ccccagtgga caccctcttc
11401 caggacagtc ctcagtggca tcacagcggc ctgagatccc caggacgcag caccgctgtc
11461 aataggggcc ccaaatgcct ggaccagggc ctgcgtggga aaggtctctg gccacactcg
11521 ggctttttgt gaagggccct cctgctgtgt gactacagta actaccatag tgatgaaccc
11581 agtggcaaaa actggctgga aacccagggg ctgtgtgcac gcctcagctt ggagctctcc
11641 aggagcacaa gagccgggcc caaggatttg tgcccagacc ctcagcctct agggacacct
11701 gggccatctc agcctgggct ggtgccctgc acaccatctt cctccaaata ggggcttcag
11761 agggctctga ggtgacctca ctcatgacca caggtgacct ggcccttccc tgccagctat
11821 accagaccct gtcttgacag atgccccgat tccaacagcc aattcctggg accctgaata
11881 gctgtagaca ccagcctcat tccagtacct cctgccaatt gcctggattc ccatcctggc
11941 tggaatcaag aaggcagcat ccgccaggct cccaacaggc aggactcccg cacaccctcc
12001 tctgagaggc cgctgtgttc cgcagggcca ggccctggac agttcccctc acctgccact
12061 agagaaacac ctgccattgt cgtccccacc tggaaaagac cactcgtgga gcccccagcc
12121 ccaggtacag ctgtagagag agtcctcgag gcccctaaga aggagccatg cccagttctg
12181 ccgggaccct cggccaggcc gacaggagtg gacgctggag ctggcccaca ctgggcatag
12241 gagctcacca gtgagggcag gagagcacat gccggggagc acccagcctc ctgctgacca
12301 gaggcctgcc ccagagccca ggaggctgca gaggcctctc cagggagaca ctgtgcatgt
12361 ctggtaccta agcagccccc cacgtcccca gtcctggggg cccctggctc agctgtctgg
12421 accctccctg ttccctggga agctcctcct gacagccccg cctccagttc caggtgtggt
12481 tattgtcagg cgatgtcaga ctgtggtgga tatagtggct acgattacca cagtggtgcc
12541 gcccatagca gcaaccaggc caagtagaca ggcccctgct gcgcagcccc aggcatccac
12601 ttcacctgct tctcctgggg ctctcaaggc tgctgtctgt cctctggccc tctgtgggga
12661 gggttccctc agtgggaggt ctgtgctcca gggcagggat gattgagata gaaatcaaag
12721 gctggcaggg aaaggcagct tcccgccctg agaggtgcag gcagcaccac ggagccacgg
12781 agtcacagag ccacggagcc cccattgtgg gcatttgaga gtgctgtgcc cccggcagcc
12841 cagccctgat ggggaagcct gtcccatccc acagcccggg tcccacgggc agcgggcaca
12901 gaagctgcca ggttgtcctc tatgatcctc atccctccag cagcatcccc tccacagtgg
12961 ggaaactgag gcttggagca ccacccggcc ccctggaaat gaggctgtga gcccagacag
13021 tgggcccaga gcactgtgag taccccggca gtacctggct gcagggatca gccagagatg
13081 ccaaaccctg agtgaccagc ctacaggagg atccggcccc acccaggcca ctcgattaat
13141 gctcaacccc ctgccctgga gacctcttcc agtaccacca gcagctcagc ttctcagggc
13201 ctcatccctg caagaaggtc aagggctggg cctgccagaa acacagcacc ctccctagcc
13261 ctggctaaga cagggtgggc agacggctgt ggacgggaca tattgctggg gcatttctca
13321 ctgtcacttc tgggtggtag ctctgacaaa aacgcagacc ctgccaaaat ccccactgcc
13381 tcccgctagg ctggcctgga atcctgctgt cctaggaggc tgctgacctc caggatggct
13441 ccgtccccag ttccagggcg agagcagatc ccaggcaggc tgtaggctgg gaggccaccc
13501 ctgcccttgc cggggttgaa tgcaggtgcc caaggcagga aatggcatga gcacagggat
13561 gaccgggaca tgccccacca gagtgcgccc cttcctgctc tgcaccctgc accccccagg
13621 ccagcccacg acgtccaaca actgggcctg ggtggcagcc ccacccagac aggacagacc
13681 cagcaccctg aggaggtcct gccaggggga gctaagagcc atgaaggagc aagatatggg
13741 gcccccgata caggcacaga tgtcagctcc atccaggacc acccagccca caccctgaga
13801 ggaacgtctg tctccagcct ctgcaggtcg ggaggcagct gacccctgac ttggacccct
13861 attccagaca ccagacagag gcgcaggccc cccagaacca gggttgaggg acgccccgtc
13921 aaagccagac aaaaccaagg ggtgttgagc ccagcaaggg aaggccccca aacagaccag
13981 gaggtttctg aaggtgtctg tgtcacagtg gggtatagca gcagctggta ccacagtgac
14041 actcacccag ccagaaaccc cattccaagt cagcggaagc agagagagca gggaggacac
14101 gtttaggatc tgagactgca cctgacaccc aggccagcag acgtctcccc tccagggcac
14161 cccaccctgt cctgcatttc tgcaagatca ggggcggcct gagggggggt ctagggtgag
14221 gagatgggtc ccctgtacac caaggaggag ttaggcaggt cccgagcact ctccccattg
14281 aggctgacct gcccagagag tcctgggccc accccacaca ccggggcgga atgtgtccag
14341 gcctcggtct ctgtgggtgt tccgctagct ggggctcaca gtgctcaccc cacacctaaa
14401 atgagccaca gcctccggag cccccgcaga gaccccgccc acaagcccag cccccaccca
14461 ggaggcccca gagctcaggg cgccccgtcg gattccgaac agccccgagt cacagcgggt
14521 ataaccggaa ccaccactgt cagaatagct acgtcaaaaa ctgtccagtg gccactgccg
14581 gagcccccgc cagagagggc agcagccact ctgatcccat gtcctgccgg ctcccatgac
14641 ccccagcacg cggagcccac agtgtcccca ctggatggga ggacaagagc tggggattcc
14701 ggcgggtcgg ggcaggggct tgatcgcatc cttctgccgt ggctccagtg cccctggctg
14761 gagttgaccc ttctgacaag tgtcctcaga gagacaggca tcaccggcgc ctcccaacat
14821 caaccccagg cagcacaggc acaaacccca catccagagc caactccagg agcagagaca
14881 ccccaatacc ctgggggacc ccgaccctga tgacttccca ctggaattc
//