GenBank-Updates@genbank.bio.net (02/16/91)
LOCUS HUMIL10 1601 bp ss-mRNA PRI 16-FEB-1991
DEFINITION Human interleukin 10 (IL10) mRNA, complete cds.
ACCESSION M57627
KEYWORDS cytokine synthesis inhibitory factor; interleukin 10.
SOURCE Human T cell line B21, cDNA to mRNA, clone H15C.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1601)
AUTHORS Vieira,P., de Waal-Malefyt,R., Dang,M.-N., Johnson,K.E.,
Kastelein,R., Fiorentino,D.F., deVries,J.E., Roncarolo,M.-G.,
Mosmann,T.R. and Moore,K.W.
TITLE Isolation and expression of human cytokine synthesis inhibitory
factor cDNA clones: Homology to Epstein-Barr virus open reading
frame BCRF1
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88, 1172-1176 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 31..567
/product="interleukin 10"
/gene="IL10"
/evidence=EXPERIMENTAL
/codon_start=31
sig_peptide 31..84
/gene="IL10"
/codon_start=31
mat_peptide 85..564
/product="interleukin 10"
/gene="IL10"
/codon_start=85
BASE COUNT 445 a 368 c 356 g 432 t
ORIGIN
1 aaaccacaag acagacttgc aaaagaaggc atgcacagct cagcactgct ctgttgcctg
61 gtcctcctga ctggggtgag ggccagccca ggccagggca cccagtctga gaacagctgc
121 acccacttcc caggcaacct gcctaacatg cttcgagatc tccgagatgc cttcagcaga
181 gtgaagactt tctttcaaat gaaggatcag ctggacaact tgttgttaaa ggagtccttg
241 ctggaggact ttaagggtta cctgggttgc caagccttgt ctgagatgat ccagttttac
301 ctggaggagg tgatgcccca agctgagaac caagacccag acatcaaggc gcatgtgaac
361 tccctggggg agaacctgaa gaccctcagg ctgaggctac ggcgctgtca tcgatttctt
421 ccctgtgaaa acaagagcaa ggccgtggag caggtgaaga atgcctttaa taagctccaa
481 gagaaaggca tctacaaagc catgagtgag tttgacatct tcatcaacta catagaagcc
541 tacatgacaa tgaagatacg aaactgagac atcagggtgg cgactctata gactctagga
601 cataaattag aggtctccaa aatcggatct ggggctctgg gatagctgac ccagcccctt
661 gagaaacctt attgtacctc tcttatagaa tatttattac ctctgatacc tcaaccccca
721 tttctattta tttactgagc ttctctgtga acgatttaga aagaagccca atattataat
781 ttttttcaat atttattatt ttcacctgtt tttaagctgt ttccataggg tgacacacta
841 tggtatttga gtgttttaag ataaattata agttacataa gggaggaaaa aaaatgttct
901 ttggggagcc aacagaagct tccattccaa gcctgaccac gctttctagc tgttgagctg
961 ttttccctga cctccctcta atttatcttg tctctgggct tggggcttcc taactgctac
1021 aaatactctt aggaagagaa accagggagc ccctttgatg attaattcac cttccagtgt
1081 ctcggaggga ttcccctaac ctcattcccc aaccacttca ttcttgaaag ctgtggccag
1141 cttgttattt ataacaacct aaatttggtt ctaggccggg cgcggtggct cacgcctgta
1201 atcccagcac tttgggaggc tgaggcgggt ggatcacttg aggtcaggag ttcctaacca
1261 gcctggtcaa catggtgaaa ccccgtctct actaaaaata caaaaattag ccgggcatgg
1321 tggcgcgcac ctgtaatccc agctacttgg gaggctgagg caagagaatt gcttgaaccc
1381 aggagatgga agttgcagtg agctgatatc atgcccctgt actccagcct gggtgacaga
1441 gcaagactct gtctcaaaaa aataaaaata aaaataaatt tggttctaat agaactcagt
1501 tttaactaga atttattcaa ttcctctggg aatgttacat tgtttgtctg tcttcatagc
1561 agattttaat tttgaataaa taaatgtatc ttattcacat c
//