GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMROSSA 1843 bp ss-mRNA PRI 21-FEB-1991 DEFINITION Human 52-kD ribonucleoprotein Ro/SSA mRNA, complete cds. ACCESSION M34551 KEYWORDS ribonucleoprotein. SOURCE Human thymocyte, cDNA to mRNA, clone FI18.1. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 1843) AUTHORS Itoh,K., Itoh,Y. and Frank,M.B. TITLE Protein heterogeneity in the human Ro/SSA ribonucleoproteins: The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genes JOURNAL J. Clin. Invest. 87, 177-186 (1991) STANDARD full staff_review COMMENT Draft entry and computer-readable [or printed] sequence for [Unpublished (1990)] kindly submitted by M.B.Frank, 18-MAY-1990. Author address: M.B.Frank Oklahoma Medical Res Foundation Arthritis and Immunology program 825 WE 13th St, Oklahoma City, OK 73104 FEATURES Location/Qualifiers CDS 39..1466 /note="52-kD Ro/SSA ribonucleoprotein" /codon_start=39 misc_signal 1827..1832 /note="poly-A signal" BASE COUNT 474 a 458 c 488 g 423 t ORIGIN 1 bp upstream of EcoRI site. 1 gaattcgggc acactgctgt ttaacggcac acttgacaat ggcttcagca gcacgcttga 61 caatgatgtg ggaggaggtc acatgcccta tctgcctgga ccccttcgtg gagcctgtga 121 gcatcgagtg tggccacagc ttctgccagg aatgcatctc tcaggttggg aaaggtgggg 181 gcagcgtctg tcctgtgtgc cggcagcgct ttctgctcaa gaatctccgg cccaatcgac 241 agctagccaa catggtgaac aaccttaaag aaatcagcca ggaggccaga gagggcacac 301 agggggaacg gtgtgcagtg catggagaga gacttcacct gttctgtgag aaagatggga 361 aggccctttg ctgggtatgt gcccagtctc ggaaacaccg tgaccacgcc atggtccctc 421 ttgaggaggc tgcacaggag taccaggaga agctccaggt ggcattaggg gaactgagaa 481 gaaagcagga gttggctgag aagttggaag tggaaattgc aataaagaga gcagactgga 541 agaaaacagt ggaaacacag aaatctagga ttcacgcaga gtttgtgcag caaaaaaact 601 tcctggttga agaagaacag aggcagctgc aggagctgga gaaggatgag agggagcagc 661 tgagaatcct gggggagaaa gaggccaagc tggcccagca gagccaggcc ctacaggagc 721 tcatctcaga gctagatcga aggtgccaca gctcagcact ggaactgctg caggaggtga 781 taattgtcct ggaaaggagt gagtcctgga acctgaagga cctggatatt acctctccag 841 aactcaggag tgtgtgccat gtgccagggc tgaagaagat gctgaggaca tgtgcagtcc 901 acatcactct ggatccagac acagccaatc cgtggctgat actttcagaa gatcggagac 961 aagtgaggct tggagacacc cagcagagca tacctggaaa tgaagagaga tttgatagtt 1021 atcctatggt cctgggtgcc cagcactttc actctggaaa acattactgg gaggtagatg 1081 tgacaggaaa ggaggcctgg gacctgggtg tctgcagaga ctctgtgcgc aggaaggggc 1141 actttttgct tagttccaag agtggcttct ggacaatttg gttgtggaac aaacaaaaat 1201 atgaggctgg cacctacccc cagactcccc tccaccttca ggtgcctcca tgccaagttg 1261 ggattttcct ggactatgag gctggcatgg tctccttcta caacatcact gaccatggct 1321 ccctcatcta ctccttctct gaatgtgcct ttacaggacc tctgcggccc ttcttcagtc 1381 ctggtttcaa tgatggagga aaaaacacag cccctctaac cctctgtcca ctgaatattg 1441 gatcacaagg atccactgac tattgatggc tttctctgga cactgccact ctccccattg 1501 gcaccgcttc tcagccacaa accctgcctc ttttccccat gaactctgaa ccacctttgt 1561 ctctgcagag gcatccggat cccagcaagc gagctttagc agggaagtca cttcaccatc 1621 aacattcctg ccccagatgg ctttgtgatt ccctccagtg aagcagcctc cttatatttg 1681 gcccaaactc atcttgatca accaaaaaca tgtttctgcc ttctttatgg gacttaagtt 1741 ttttttttct cctctccatc tctaggatgt cgtctttggt gagatctcta ttatatcttg 1801 tatggtttgc aaaagggctt cctaaaaata aaaacccgaa ttc //