GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS MUSTGFB1 2716 bp ds-DNA ROD 21-FEB-1991
DEFINITION Mouse transforming growth factor-beta-1 (TGF-beta-1) gene 5' end,
and promoter region.
ACCESSION M57902
KEYWORDS regulatory protein; transforming growth factor-beta-1.
SOURCE Mouse (BALB/c) adult liver DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2716)
AUTHORS Geiser,A.G., Kim,S.-J., Roberts,A.B. and Sporn,M.B.
TITLE Characterization of the mouse transforming growth factor-beta-1
promoter and activation by the Ha-ras oncogene
JOURNAL Mol. Cell. Biol. 11, 84-92 (1991)
STANDARD simple staff_review
FEATURES Location/Qualifiers
promoter 1..1846
/note="promoter 1"
/gene="TGF-beta-1"
/evidence=EXPERIMENTAL
promoter 1847..2713
/note="promoter 2"
/gene="TGF-beta-1"
/evidence=EXPERIMENTAL
mRNA 1847..2716
/product="transforming growth factor-beta-1"
/gene="TGF-beta-1"
/evidence=EXPERIMENTAL
/partial
mRNA 2137..2716
/product="transforming growth factor-beta-1"
/gene="TGF-beta-1"
/evidence=EXPERIMENTAL
/partial
CDS 2714..2716
/product="transforming growth factor-beta-1"
/gene="TGF-beta-1"
/evidence=EXPERIMENTAL
/codon_start=2714
/partial
BASE COUNT 508 a 858 c 784 g 566 t
ORIGIN
1 ggatcctctt gcctctacct cccaagtgct ggcattccag ctgtacactg cagtgttcag
61 ccccaaatgt caccttcttt aggaaagctt ccttcagctg ctccccaatt ttccaaacta
121 catctccacc cctccctttc tggctgttgt ttttccccag agcggttatc accatatgac
181 ataccctata atttacttat ttactatgtt ggttgtctag gatgtcagct tcacggggca
241 ggaatttttg tctgctgtgt tcattgctgt gtccccagcc tggagaacag ggcctgccag
301 gggagggctt agggttgggg gggggggggg ctgggctgca tctccaagca ttggactgtc
361 aggctgggac actcagctgt gcattgaggc cactagaaac ctaacgaagg ggagagatgg
421 ctccactggg gaagaaagga aatctgagtc aggtgcgtga gagcaaagca agtccatgag
481 gaggagggcg gaaggggtcc taagctgagg tgctgacctg ggggcctggg agagtgaaga
541 gaccacaaag ggaggtcaga cgaggccaga cttgacttga gaggttggac tttgttctgt
601 ggcccagggg agtcatggga gggttttgag caagagggta atgtggattg ctctagattc
661 ctgtgactac tatgtggagt gagtgggaga tgagaaccca gagaggaaat tcaggcaata
721 atccaaggta aaagtactgt gcgaggtctc cagtggtttc aatgctggga acccgggagc
781 agggttctgc ccctttgtcc ttttctctaa cgcctctcct cccgcaggtt ggcctcgact
841 ccatctccag gtgtggtccc aggacagctt tggccgctgc cagcttgctg gctatggctt
901 ttgccatgtg cctagcagcc caggcactca tcagctggac tgccctacat ggaggcccct
961 gggcagttgg agggagcagc tagcacgggc tttcgtgggt ggtgggccac agctgctgca
1021 cgcagatacc atctacagcg gggctgaccg ctaccgcctg cacacggccg cgggtggcac
1081 agtgcacctt ggtatcggcc tgctgctgcg ccacttcgat cgctatggag tggagtgttg
1141 agggacttca ttgctactaa tcgccatcat ccactgagca cataatggca cagcagtgaa
1201 gcaggcacgt ggactctgga gactgtcagt cctgatcacc cccaagtcat ggcccctatg
1261 ccatggactg caaggccagg aactcccctg tggcccatgc tccactgaac tacggggtag
1321 aaagggctgt gggttggagg gacatgagca gggcccactg tttggactgt cgggggcact
1381 taataaaagc gtgtatttct catgggtaag gtgcctcctt gtatccgcta aagctctcag
1441 acgtcggtct ccttatttca ctctccttga cactctcatc cgcaaagtct gcccctgcct
1501 ttcgctctcc accgcctagg tccccacttc taatacagga ctctgttttc tcacgaagtc
1561 ccaatttttc ctttgaccct tcaacaactc ccaaatccac cggggcgctt tggttggtca
1621 ccggctttag tagtgctccg ccgccaggag gcagcaccct ggaggtgggg cgaggccggg
1681 gtgcccgccc cctccccgca ggctgaaggg accccccttg gagcccgccc acgctaagat
1741 gaagacagtg cccccccatg ccctccccct ggggctgccc ccgccccgcg cgcgcttcct
1801 gggtggggcc ggggcggctt caaaaccccc gccgccccag ccggtcccgc cgccgccgcc
1861 gcccttcgcg cccaggccgt ccccctcctc ctcccgccgc ggatcctcca gacagccagg
1921 cccccggccg gggcaggggg gacgcccctt cggggcaccc ccggctctga gccgcactcg
1981 gagtcggcct ccgctgggag ccggcaaagg agcagccgag gagccgtccg aggccccaga
2041 gtctgagacc agccgccgcc gcagggagga gggggaggag gagtgggagg agggacgagc
2101 tggttgagag aagaggaaaa aagttttgag acttttccgc tgctactgca agtcagagac
2161 gtggggactt cttggcactg cgctgtctcg caaggaggca ggacctgagg actccagaca
2221 gccctgctca ccgtcgtgga cactcgatcg ctacccggcg ttcctcagac gcccctattc
2281 cggaccagcc ctcgggagcc acaaaccccg cctcccgcga agacttcacc ccaaagctgg
2341 ggcgcacccc ttgcacgccg ccctcccccc agcctgcctc ttgagtccct cgcatcccag
2401 gaccctctct cccccgagag gcagatctcc ctcggacctg ctggcagtag ctcccctatt
2461 taagaacacc cacttttgga tctcagagag cgctcatctc gatttttacc ctggtggtat
2521 actgagacac cttggtgtca gagcctcacc gcgactcctg ctgctttctc cctcaacctc
2581 aaattattca ggactatcac ctacctttcc ttgggagacc ccaccccaca agccctgcag
2641 gggcggggcc tccgcatccc acctttgccg agggttcccg ctctccgaag tgccgtgggg
2701 cgccgcctcc cccatg
//