GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMGXA 3957 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human Gx-alpha protein gene.
ACCESSION D90150 J05541
KEYWORDS Gx-alpha protein; pertussis toxin-insensitive G protein.
SOURCE Human genomic DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3957)
AUTHORS Matsuoka,M., Itoh,H. and Kaziro,Y.
TITLE Characterization of the human gene for G-X-alpha, a pertussis
toxin-insensitive regulatory GTP-binding protein
JOURNAL J. Biol. Chem. 265, 13215-13220 (1990)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by:
Masaaki Matsuoka
Institute of Medical Science
Tokyo University
4-6-1 Shirokanedai, Minatoku
Tokyo 108
Japan
Phone: 03-443-8111
Fax: 03-445-5168
The sequences of two introns are completely omitted in [J. Biol.
Chem. 265, 13215-13220 (1990)].
These introns located between 751 and 752 and between
1923 and 1924, respectively.
FEATURES Location/Qualifiers
CDS join(1201..1923,1924..2268)
/note="Gx-alpha protein, coding region of"
misc_signal 555..560
/note="GC Box"
misc_signal 568..573
/note="GC Box"
misc_signal 572..577
/note="GC Box"
mRNA 582..3870
/note="Gx-alpha protein mRNA"
exon 1201..1923
/note="Gx-alpha protein, coding region of exon 2"
exon 1924..2268
/note="Gx-alpha protein, coding region of exon 3"
BASE COUNT 838 a 1163 c 1189 g 767 t
ORIGIN
1 caatccagga gagcaggtgc cactagcccc actttgcaaa cagaaaggct gggagaggtc
61 agtcggttgc ccaaggacgt gagagctcac aagaggccga actgggtttg aacccgagtg
121 gagagaaggc gagccgggac tggctgcagt aaagagggcc aggaccatgg ctgggctcag
181 gcttggtttc ccgggctgcc agaggtggcc cctggggctc ggctaccagg cctcagcgca
241 gcggagtcgg tggaacgccg gcgcggggag ctcttgcggg actgcggcgc gcgcggagct
301 gccaccccgc ccctgtccgt ccccattggg ctactggccc gtccgtcagc tgcctgtgcc
361 caatggacag agggccggcg ctcgtggcgg ggcggaggtg cccggcgcgt ggtgcccggc
421 gggcgcgcgg cacccccccg cccgcggttg gcctggcaac gggctgcgct cgcggctccg
481 ccccctgccg gcggcggcgc ggcgcggggc gggcggaccc gcggactggc ggcgggcggc
541 gggcggcggg cggcgggcgg cgcgggaggg cgggcggagg gaaccaggcc ggccggagcg
601 tgtgcgccgc ccgcggtccg gtcacgtccc cgcgtgggcg ccgctgcccg cgtcgtacgg
661 aacgagggcg ccgcggcccc gtgctcgccg ccccgccccg ccccgccctg cccggagcag
721 ctcggcagat gctctgtgct gcggcccgga ggtgaagggc tggatgcaca gtgggagccg
781 gaggcggggg gctgcaggga gcacaccagc gaccggccct ccaaccctcc agccactcag
841 caacatcgcc acagcaacca gcaaccagac ggcagcagcc gaggcaaaca caagcggacg
901 gcttcccacc gtcgccgagg acagggaatg actacggcaa atcaggccac tttgccaact
961 agggaggtgg agtgtcacta gtggggaggg gcggccaccg cccgctgcac agagcgccat
1021 gccggctgga gaagaggcgc tggggcaggg gctgcagtgt ggctcggcct cacccccctg
1081 ctggcactga gtgcctccag ggcagctggg ctcttgtctg cctggtctca gtgtcccctg
1141 tggcaagagg gagaggtgcc ccatcccgtg ctccttgtct gggcccgctg ctgccagacc
1201 atgggatgtc ggcaaagctc agaggaaaaa gaagcagccc ggcggtcccg gagaattgac
1261 cgccacctgc gctcagagag ccagcggcaa cgccgcgaaa tcaagctgct cctgctgggc
1321 accagcaact caggcaagag caccatcgtc aaacagatga agatcatcca cagcggcggc
1381 ttcaacctgg aggcctgcaa ggagtacaag cccctcatca tctacaatgc catcgactcg
1441 ctgacccgca tcatccgggc cctggccgcc ctcaggatcg acttccacaa ccccgaccgc
1501 gcctacgacg ctgtgcagct ctttgcgctg acgggccccg ctgagagcaa gggcgagatc
1561 acacccgagc tgctgggtgt catgcgacgg ctctgggccg acccaggggc acaggcctgc
1621 ttcagccgct ccagcgagta ccacctggag gacaacgcgg cctactacct gaacgacctg
1681 gagcgcatcg ccgcagctga ctatatcccc actgtcgagg acatcctgcg ctcccgggac
1741 atgaccacgg gcattgtgga gaacaagttc accttcaagg agctcacctt caagatggtg
1801 gacgtggggg ggcagaggtc agagcgcaaa aagtggatcc actgcttcga gggcgtcaca
1861 gccatcatct tctgtgtgga gctcagcgcc tacgacctga aactctacga ggataaccag
1921 acaagtcgga tggcagagag cttgcgcctc tttgactcca tctgcaacaa caactggttc
1981 atcaacacct cactcatcct cttcctgaac aagaaggacc tgctggcaga gaagatccgc
2041 cgcatcccgc tcaccatctg ctttcccgag tacaagggcc agaacacgta cgaggaggcc
2101 gctgtctaca tccagcggca gtttgaagac ctgaaccgca acaaggagac caaggagatc
2161 tactcccact tcacctgcgc caccgacacc agtaacatcc agtttgtctt cgacgcggtg
2221 acagacgtca tcatacagaa caatctcaag tacattggcc tttgctgagg agctgggccc
2281 ggggcccgcc tgcctatggt gaaacccacg gggtgtcatg ccccaacgcg tgctagagag
2341 gcccaatcca ggggcagaaa acagggggcc taaagaatgt cccccacccc ttggcctctg
2401 cctccttggc cccacatttc tgcaaacata aatatttacg gatagattgc taggtagata
2461 gacacacaca catgcacaca cacacatctg gagatggcaa aatcctctaa aatgtcgagg
2521 tctcttgaag acttgagaag ctgtcacaag gtcactacaa gcccaacctg ccccttcact
2581 ttgccttcct gagttggccc actccacttg ggggtctgca ttggattgtt agggataggc
2641 agcagggctg aggcaaggta ggccaactgc acccctgtcg cctggaggag ggccagctcg
2701 ctgcccgagc tctggcctag ggaccttgcc gctgaccaag agggaggacc agtgcagggt
2761 ctgtgcacct tccctgctgg cctgcacaca gctgctcagc accactttca ttctggacct
2821 gggaccttag gagccgggtg acagcactaa ccagacctcc agccactcac agctcttttt
2881 aaaaaacagc ttcaaaatat gcagcaaaaa ccaatacaac aaaacgagtg gcacgattta
2941 tttcaaacta ggccagctgg gattccagct tttcttctac tagtctgatg ttttataaat
3001 caaaacctgg ttttccttct ctggcatttt ttttttgttt tgttttttgg tttttttttt
3061 tttttggcca aatctcgtgg tgtttcgcag aaaaaaatcc agaaaatttc aaatgcagtt
3121 gagtattctt ttttaaatgc agattttcaa aacatatttt ttttcaggtg gtcttttttg
3181 tgtctggctt gctgagtgta aaagttgtta tctggacgat ctgtctctct gctccaaaga
3241 aattttggag tgagtgcagt cctgcgccag cctcgcggga cacgtgttgt acataagcct
3301 ctgcagtgtc ctcttgttaa tggtggggtt ttctgctttg tttttattta agaaaataaa
3361 cacgacatat ttaaagaagg ttctttcacc tgggagcaaa tgaacaatag ctaagtgtct
3421 tggtatttaa agagtaaatt atttgtggct ttgctgagtg aaggaagggg agcaaggggt
3481 ggtgcccctg gtcccagcat gccccgcgcc tgagactggc tggaaatgct ctgactcctg
3541 tgaaggcaca gcccagcgtt gtggcctgag ggaggccctg ctgggaccct gatctgggcc
3601 ttcctgtccc agggcctatg ggcaactgcg ttgaaaggac gttcgccaag ggccgtgtgt
3661 aaatacgaac tgcgccatgg agaggagagg cactgccgga gcccttgcca gatctccctc
3721 cctctctcct gttgcagtag ctgtgtgtcc gaggtcagtg tgcggaatca cagccaagga
3781 cgtgaagaga tgtacggggg aaagagaagc tggggattgg atgaaagtca aaggttgtct
3841 actttaagaa aataaaatac cctgaatgga gcccagcatt gtcccagtgt gctatgtgtg
3901 tagctgacct gtggctggac ttggtgccat ctggaagggc agccggggac acctcca
//