GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS CRECAH1G 5009 bp ds-DNA PLN 21-FEB-1991
DEFINITION C.reinhardtii carbonic anhydrase (CAH1) gene, complete cds.
ACCESSION D90206 D90114 X54487
KEYWORDS carbonic anhydrase.
SOURCE C.reinhardtii (strain C-9 mt(-) haploid), genomic DNA, clones F1
and gtCA3.
ORGANISM Chlamydomonas reinhardtii
Eukaryota; Plantae; Thallobionta; Chlorophycota; Chlorophyceae;
Volvocales; Chlamydomonadaceae.
REFERENCE 1 (bases 3938 to 4819)
AUTHORS Fukuzawa,H., Fujiwara,S., Yamamoto,Y., Dionisio-Sese,M.L. and
Miyachi,S.
TITLE cDNA cloning, sequence, and expression of carbonic anhydrase in
Chlamydomonas reinhardtii: Regulation by environmental CO2
concentration
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 4383-4387 (1990)
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 5009)
AUTHORS Fukuzawa,H., Fujiwara,S., Tachiki,A. and Miyachi,S.
TITLE Nucleotide sequences of two genes CAH1 and CAH2 which encode
carbonic anhydrase polypeptides in Chlamydomonas reinhardtii
JOURNAL Nucleic Acids Res. 18, 6441-6442 (1990)
STANDARD full staff_entry
REFERENCE 3 (bases 1 to 5009)
AUTHORS Fujiwara,S., Fukuzawa,H., Tachiki,A. and Miyachi,S.
TITLE Structure and differential expression of two genes encoding
carbonic anhydrase in Chlamydomonas reinhardtii
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 9779-9783 (1991)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by:
Hideya Fukuzawa
Institute of Applied Microbiology
University of Tokyo
1-1-1 Yayoi, Bunkyo-ku
Tokyo 113
Japan
Phone: 03-812-2111 x7846
Fax: 03-812-2910
The amino acid sequence Thr-168 reported by Kamo et. al. in
Eur. J. Biochem. 192:557-562 (1990) was revised to Ser-168
in [Proc. Natl. Acad. Sci. U.S.A. 87, 4383-4387 (1990)].
FEATURES Location/Qualifiers
precursor_RNA <562..4819
/note="carbonic anhydrase mRNA and introns"
CDS join(592..687,950..999,1185..1239,1455..1529,1850..1904,
2225..2287,2409..2534,2741..2875,3098..3342,3499..3643,
3938..4026)
/note="carbonic anhydrase (EC 4.2.1.1) precursor"
mat_peptide join(652..687,950..999,1185..1239,1455..1529,1850..1904,
2225..2287,2409..2534,2741..2875,3098..3342,3499..3618,
3619..3643,3938..4023)
/note="carbonic anhydrase, large subunit"
misc_signal 382..391
/note="AGCGGCTCGC element"
misc_signal 442..445
/note="CAAT box"
misc_signal 521..524
/note="TATA box"
exon 592..687
/note="carbonic anhydrase (EC 4.2.1.1) precursor, exon 1"
sig_peptide 592..651
/note="carbonic anhydrase signal peptide"
intron 688..949
/note="carbonic anhydrase intron 1"
exon 950..999
/note="carbonic anhydrase precursor, exon 2"
intron 1000..1184
/note="carbonic anhydrase intron 2"
exon 1185..1239
/note="carbonic anhydrase precursor, exon 3"
intron 1240..1454
/note="carbonic anhydrase intron 3"
exon 1455..1529
/note="carbonic anhydrase precursor, exon 4"
intron 1530..1849
/note="carbonic anhydrase intron 4"
exon 1850..1904
/note="carbonic anhydrase precursor, exon 5"
misc_feature 1874..1876
/note="glycosylation site"
intron 1905..2224
/note="carbonic anhydrase intron 5"
exon 2225..2287
/note="carbonic anhydrase precursor, exon 6"
intron 2288..2408
/note="carbonic anhydrase intron 6"
exon 2409..2534
/note="carbonic anhydrase precursor, exon 7"
misc_feature 2417..2419
/note="glycosylation site"
misc_binding 2501..2503
/note="zinc binding histidine residue"
misc_binding 2507..2509
/note="zinc binding histidine residue"
intron 2535..2740
/note="carbonic anhydrase intron 7"
exon 2741..2875
/note="carbonic anhydrase precursor, exon 8"
misc_binding 2764..2766
/note="zinc binding histidine residue"
intron 2876..3097
/note="carbonic anhydrase intron 8"
exon 3098..3342
/note="carbonic anhydrase precursor, exon 9"
misc_feature 3331..3333
/note="glycosylation site"
intron 3343..3498
/note="carbonic anhydrase intron 9"
exon 3499..3643
/note="carbonic anhydrase precursor, exon 10"
intron 3644..3937
/note="carbonic anhydrase intron 10"
exon 3938..4026
/note="carbonic anhydrase precursor, exon 11"
misc_signal 4796..4800
/note="poly(A) signal"
misc_feature 4814..4819
/note="poly(A) site"
repeat_region 4932..4981
/note="A-C repeat"
BASE COUNT 1004 a 1553 c 1423 g 1029 t
ORIGIN
1 gaattcccta cctccacgct tccgtgcctc cccaaccctc cgaagacccg ccagaatgtg
61 tccataggca cccatatgcg tgcagagcac gcatgatttc tgctcctgga cctggagcca
121 atcaaatcca gtccgcaggg ctccggtcca gcccagcctt ccacaccggc tgggcgccca
181 gcaacccaac agccgcaaga ataaaatagt caaggctgta gcctttcaag ccgcgccacc
241 acgttggcag cgttgtagat tttcaccggt tggaaggagg tttgacgcga gggatttagg
301 tgcgagtccg acttacgaac tgcgaaaagg gttccccctt tgccccgggg tatgacatgg
361 gtgccggaac tccaaccaag tagcggctcg caaccccggc tgcagactgt gcgcatgcag
421 aaatgcagct tctggtttta acaattgttt gatggcatat gcgatttctc tccacgccca
481 tgtgacggcc agcgaccgcc gtaccgttgt cactttttga tataagtccg gatgcaacca
541 tagttgtcca caccctgcgt tgagtcatta cctgcaaccc acttgaacac catggcgcgt
601 actggcgctc tactcctggt cgcgctggcg cttgcgggct gcgcgcaggc ttgcatctac
661 aagttcggca cgtcgccgga ctccaaggtg cgcacttgaa ataggctaac cgactcgaac
721 aatgaaccaa gaacaagctt gtcaagcaga tgcatgattc ggctgttggt tgccgatgcg
781 caattctatg cctcgacaag gccgccgccg cgtcgtgagc atatcgatcg gccaacctgt
841 ccagccatct gttgtgatag gctgtttgcg cccccactca gccttgctgt gccaagtcgt
901 tgcttttcgc gttgtgagaa cagatttcgt catcgcgatt gttttacagg ccaccgtttc
961 gggtgatcac tgggaccatg gcctcaacgg cgagaactgg taaggccctt ggatgcagtc
1021 agacacatgc atgcatgact tgacgtttgc gacggatgct gggcgcgcac tgctttgcat
1081 cgctgcattt gcaacacgcc cttgtgtgct caacatggga ttgtggtcag gctagggcga
1141 tgaacggttc tggtccctgt cgacttgggc atccccacat acagggaggg caaggacggc
1201 gcaggcaacg cctgggtttg caagactggc cgcaagcagg tccgtggaca acgcggatca
1261 atgacggctt ttcagcaaga ccgcttagca tgaaaacacg actgcacggg acgggttgca
1321 tgggacggac tggcggaccg aactcttgcc gtgcccccca cccccccccc ccccgccccc
1381 caccccccaa cagttcatca tgttgcgcgt gaccccttac cccgcccctt cctcccccgc
1441 aaccgcacgc gcagtcgccc atcaacgtgc cccagtacca ggtcctggac gggaagggtt
1501 ccaagattgc caacggcctg cagacccagg tgggtagcca acagggtgta acggtgggag
1561 gcagcgtgtc gcgccacgtg tgctgtcacg gcgccatcca acctaaccgg cccgccagcg
1621 ccccggaagg cgttgcgcgg agactggagc acgggcaagg gttcaagcac cctaacatgg
1681 gaggagtcag ggtttccatg gttggatggc ccggtttatt ttgccggggc gagccgcctg
1741 attgcgatta accaccggtt ttgtaccgcg caacgccggc cagattgcca gcgggtttca
1801 ctggccactt taacctccct cctctttccc tgccttgttc atactgcagt ggtcgtaccc
1861 tgacctgatg tccaacggca cctcggtcca agtcatcaac aacggtgaga gcgaggcgat
1921 gtggctggat gggttttgca acgcggcgga ccgcacagaa ggattcatag cgccaagcag
1981 tttagattgc atttgctacg gaagggacct gccagctgac gcagttcacg agccggtagc
2041 gtggagtgcg agcacgctta gtaacccagc cttgtgcgca gtcatgcatc tgggtgcctt
2101 ggtttcttgc aggcgttgtg gggcgaagaa gtttgttgca gtatctggga cactgcggtg
2161 gttttctacg gtcggtaacc tcaccaaatc ctgcctgcct ccatcccgcc acccctatcc
2221 tcaggccaca ccatccaggt gcagtggact tacaactacg ccggccatgc caccatcgcc
2281 atccctggtg cgtcagctgg tgctgcatct ctgcatctcc tatctattcg gtaccatagc
2341 gtgccaacgc cgcgtatctt gtctcacgtc attggtaacc tcctccttct cctcccacgt
2401 gctcgcagcc atgcacaacc agaccaaccg catcgtggac gtgctggaga tgcgccccaa
2461 cgacgccgcc gaccgcgtga ctgccgtgcc cacccagttc cacttccact ccacctcgga
2521 gcacctgctg gcgggtgcgt gggcgtgggc gcaactcttg acttttgaca ggggcgggtg
2581 ttgagaaggg tgttgggaga ggtgtaaagc tctaagtagg caatgggctc caaccaaacg
2641 aaaggtccca caagtcccaa cccccacccc acctagcacc tgccttccgc acacaacaca
2701 tccgctggtg cctttccttc gttacgtcta ccgcctacag gcaagatcta tccccttgag
2761 ttgcacattg tgcaccaggt gactgagaag ctggaggcct gcaagggcgg ctgcttcagc
2821 gtcaccggca tcctgttcca gctcgacaac ggccccgata acgagctgct tgagcgtgag
2881 tcgggcagca ggggcggggt ggtggaggcg gggcgggggc gggtttgtac gaagctgtca
2941 cggtttgtgt ggatttggta cgtacgtgca tggcagaccg ctgagcgctt ctcaggaggt
3001 gcctcatcca gtgcctctat ttcatcctct gttgtgccct tacatgctcg tttgcacgtt
3061 tactgatcgc cacacttcat cggcccgtcc tctgcagcca tctttgcgaa catgccctcg
3121 cgcgagggca ccttcagcaa cctgccggcg ggcaccacca tcaagctggg tgagctgctg
3181 cccagcgacc gcgactacgt aacgtacgag ggcagcctca ccaccccgcc ctgcagcgag
3241 ggcctgctgt ggcacgtcat gacccagccg cagcgcatca gcttcggcca gtggaaccgc
3301 taccgcctgg ctgtgggcct gaaggagtgc aactccacgg aggtaagacg cccctacaaa
3361 cgggggagtc ctgggaacgg gcaagaagag cgaggtgtcg ggtgacggtg gcggctgccg
3421 ggtcaaatct gcgtcactgg tcagtgctcc tgtcacgcac gcctatgtgc tgcccatgtt
3481 catttaccac gcgtgcagac cgccgcggac gccggccacc accaccacca ccgccgcctg
3541 ctgcacaacc acgcgcacct ggaggaggtg cctgccgcca cctccgagcc caagcactac
3601 ttccgccgcg tgatgctggc cgagtccgcg aaccccgatg cctgtgagtt tacctgagag
3661 tggtaaaaag ggagtaccgg catgcattgt accctagaag ctgggcgagg gcgcggtatc
3721 ccaaaggctc ccccaagggg agacaccgag tcatgcgtgc tgagttccat tggattgcgt
3781 ctgcccaata gtcggtccga gctgctgcca agcaagtccg tgcacgtggt cgtccactcc
3841 tgcgtgtgcc tgcgcgcctg cgcgccgtgt ttcttttgta acgcccccta accccgacct
3901 tattgcctcc ctctttgcct cccccccaat gcgacagaca cctgcaaggc cgttgccttt
3961 ggccagaact tccgcaaccc ccagtacgcc aacggccgca ccatcaagct ggcccgctat
4021 cactaaactt cccagtagtt agtcacgcta ccaccgtcgg cacggccagc aggcattcca
4081 ttttccaggc tttgcttcac ggtttggtgt gtcattcgat ggtgttcttg acgacccgcg
4141 cttggcgggc ctttccaatt ttttccatag tacaccgaaa tagttctgcg gtgcagcacg
4201 catacacaca gtaccggacg ggcggcggga cctcctgttt tctcctgact agtaaagaag
4261 taaggaaggt atggagttgg ttccacgatg gggcagtctg agagcggaat aaagtcagtg
4321 ggccggacgt tgtggcgatg gatggtagtg aggcaagtaa tacgtacgta gagggcgtac
4381 gcgggtaata acgggaactt cgacagcaat cgagagtgtc tgcacgcgag acatttgcgt
4441 acaggggagg caccggttct cctcgatgag tgatccgtac ttatgcaagt tatataaggc
4501 tggtgtgggg cgcttcagca cggtatggtt gccagcatgc acggtccggc ctctgtctgg
4561 ctggctgggt tgttggcggg ctggcctcat gcgcgccgtc gcacatgccg atcaatgcag
4621 ttgctctcca gtagctgcaa ggcctggctg ggcaatccca tagccatgtc gaatgtgaag
4681 cattgttttc ttggagatgg aggacaggag acgctgaccg gatgttttaa gacgtgcagg
4741 atgtggggag cgaggtagct acaacggtgc agttgaggca gagacgtgta cgacatgtaa
4801 gatgcccatg gacaaaaaag gccctgggtg tccctcgcaa agggaaaacg tgggctgcgc
4861 cccaaaagtg ggcacaagtc acgcctcccg tctgaggccg caagtgtcta cctcatcgcc
4921 aggggatagc aacacacaca cacacacaca cacacacaca cacacacaca cacacacaca
4981 ccgcaacgcc acacactgtg tgtcccgag
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS CRECAH2G 4858 bp ds-DNA PLN 21-FEB-1991
DEFINITION C.reinhardtii carbonic anhydrase (CAH2) gene, complete cds.
ACCESSION D90207 X54488
KEYWORDS carbonic anhydrase.
SOURCE C.reinhardtii (strain C-9 mt(-) haploid), genomic DNA, clones F1
and F9.
ORGANISM Chlamydomonas reinhardtii
Eukaryota; Plantae; Thallobionta; Chlorophycota; Chlorophyceae;
Volvocales; Chlamydomonadaceae.
REFERENCE 1 (bases 1 to 4858)
AUTHORS Fukuzawa,H., Fujiwara,S., Tachiki,A. and Miyachi,S.
TITLE Nucleotide sequences of two genes CAH1 and CAH2 which encode
carbonic anhydrase polypeptides in Chlamydomonas reinhardtii
JOURNAL Nucleic Acids Res. 18, 6441-6442 (1990)
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 4858)
AUTHORS Fujiwara,S., Fukuzawa,H., Tachiki,A. and Miyachi,S.
TITLE Structure and differential expression of two genes encoding
carbonic anhydrase in Chlamydomonas reinhardtii
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 9779-9783 (1991)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by:
Hideya Fukuzawa
Institute of Applied Microbiology
University of Tokyo
1-1-1 Yayoi, Bunkyo-ku
Tokyo 113
Japan
Phone: 03-812-2111 x7846
Fax: 03-812-2910
All the features are predicted by comparing with CAH1.
FEATURES Location/Qualifiers
precursor_RNA <491..>4667
/note="carbonic anhydrase mRNA and introns"
CDS join(491..586,855..904,1074..1128,1245..1319,1654..1708,
2022..2084,2288..2413,2592..2726,2968..3212,3414..3567,
3714..3802)
/note="carbonic anhydrase (EC 4.2.1.1) precursor"
mat_peptide join(551..586,855..904,1074..1128,1245..1319,1654..1708,
2022..2084,2288..2413,2592..2726,2968..3212,3414..3542,
3543..3567,3714..3799)
/note="carbonic anhydrase, large subunit"
misc_signal 245..248
/note="CAAT box"
misc_signal 303..312
/note="AGCGGCTCGC element"
misc_signal 340..345
/note="TATA box"
misc_signal 372..375
/note="CAAT box"
misc_signal 428..431
/note="TATA box"
exon 491..586
/note="carbonic anhydrase (EC 4.2.1.1) precursor, exon 1"
sig_peptide 491..550
/note="carbonic anhydrase signal peptide"
intron 587..854
/note="intron 1"
exon 855..904
/note="carbonic anhydrase, exon 2"
intron 905..1073
/note="intron 2"
exon 1074..1128
/note="carbonic anhydrase, exon 3"
intron 1129..1244
/note="intron 3"
exon 1245..1319
/note="carbonic anhydrase, exon 4"
intron 1320..1653
/note="intron 4"
exon 1654..1708
/note="carbonic anhydrase, exon 5"
misc_feature 1678..1680
/note="glycosylation site"
intron 1709..2021
/note="intron 5"
exon 2022..2084
/note="carbonic anhydrase, exon 6"
intron 2085..2287
/note="intron 6"
exon 2288..2413
/note="carbonic anhydrase, exon 7"
misc_feature 2296..2298
/note="glycosylation site"
misc_binding 2380..2382
/note="zinc binding histidine residue"
misc_binding 2386..2388
/note="zinc binding histidine residue"
intron 2414..2591
/note="intron 7"
exon 2592..2726
/note="carbonic anhydrase, exon 8"
misc_binding 2615..2617
/note="zinc binding histidine residue"
intron 2727..2967
/note="intron 8"
exon 2968..3212
/note="carbonic anhydrase, exon 9"
misc_feature 3201..3203
/note="glycosylation site"
intron 3213..3413
/note="intron 9"
exon 3414..3567
/note="carbonic anhydrase, exon 10"
intron 3568..3713
/note="intron 10"
exon 3714..3802
/note="carbonic anhydrase, exon 11"
misc_signal 4663..4667
/note="poly(A) signal"
BASE COUNT 954 a 1456 c 1439 g 1009 t
ORIGIN
1 ctgcaggaag gtgaccagca tccacggatg agcaccagag gcaaccgcag agcaaggctg
61 acagtcgtcg tccgaggcca gccatggtta ttgccgaaag gggagctcca ggggagcggg
121 ggccgggggg aggggggctg gagacagctg gaggcggggg caaggcgcag acatgcagcg
181 agtcgaagcc caaacgcacg gagcccgaca ggcgctcaca tgaaacttcc tcgtgtgact
241 catgcaatct gatggcagac aacggcccgc tccaagctgc agagcggcgc ggcttcagat
301 gcagcggctc gcccacgtcc gcgacaaaca actggtttgt atatatgtct gttgtaaagc
361 ttgctggctg gcaatcctgg cgcgctgacg atgaaagtac ggcttgatgc cacgcttttc
421 ggcgcgataa aagcatgctt cgtagggcaa tttgggatag tttgttacta caattgatca
481 attgaacacc atggcgcgta ctggcgctct actcctggcc gcgctggcgc ttgcgggctg
541 cgcgcaggct tgcatctaca agttcggcac gtcgccggac tccaaggtgc gcacgtccga
601 agctgcatgt ctcgcaatga tcaagtgcga gttggaacga ggatgttgtt ttggcccctg
661 gttgccgttt ggcataaacg tgaatgtctc accgcgactg cgtcactgag cattcaactg
721 ctcgtttccg gctgcaaatg aagtcatatc catgggtatt actactagtc ggcattctgc
781 gcagcttcgg gcaggcatgc ccgttgcttg ggtgagtcct gaccgccgct tgcgccctcg
841 cttttgtttg acaggccact cacacaggcg accactggga tcatagtctc aatggcgaga
901 actggtaagg acctggcctg ctcacatgaa tggagtgact tgtggccgcc gtccggcacc
961 cactgctttg cacccctgaa ttattagtgc ggcgctaggc gcttgcgttg gttgcgcggg
1021 atcgcggcga ggccatgaga gaccaaacgg acttttttcg ccatcgcacg cagggagggc
1081 aaggacggcg cgggcaaccc ctgggtctgc aagactggcc gcaagcaggt ccgtaacaat
1141 acatgttgag agtttctgcc gactgggcat tgtcacgtga actttctggg aggttgccct
1201 cgaattcgct cccgcccctt cctcccccgc aaccgcacgc gcagtcgccc atcaacgtgc
1261 cccagtacca tgtcctggac gggaagggtt ccaagattgc caccggcctg cagacccagg
1321 tgagtagcca gcatgacaca acaggccagc gtagtgcgcc gccttgcgcc gcgtgtgcga
1381 gggtgtgtgc ctgtcacggc gccatccaac ttaaccgcct ggcttgcgcc ccgaagcgtg
1441 cttgcgcgta gactggagca ggggcaatgg tttcaagcat cctaacatgg gaggcatcag
1501 ggtttccatg gttgggtggc ccggttttgc tggtgcgaac ctcctgattg cgatcaacgg
1561 ccggttttgt gccgcaacgc cagccagatt gacagcgggt ttttaaggcc ccgttactct
1621 ccattctctt tccctgcctt attaatactg cagtggtcgt accctgacct gatgtccaac
1681 ggcagctcgg ttcaagtcat caacaacggt gcgagagaga cggcaaggtg gccggtgggc
1741 ttttgcaacg cggcggaccg cacagaaagg attcatggcg ccaagccgtt tagttgcatt
1801 tgctacaaaa gggacgcagt ccacaagccg gtagcgtgga gtgcgagcac gcttggtcac
1861 cccgccttgt gcggtagctg agacaccacg gcgcttgggg tctgttgtgt caaggattca
1921 agcaccagac ccaatccatg caagcacgtg gtgtttccgc taaacctgac tgaagcattt
1981 tgcctgcctg cctccatccc gccactccat cctgctctca ggccacacca tccaggtgca
2041 gtggacctac gactacgccg gccatgccac catcgccatc cctggtgcgt cagctggtgc
2101 tgcatctacc gcattacgcc agtgcaggcc ctgtcgacaa cccaatccgc aatcactggc
2161 cccttttctt cccatgacga catcggtcct tgatgcttac aagtgttagt gcttcccaga
2221 taggcatatc cacgtaccgt cttgacctct tctcgccccc catgcccgtc ctcccacgtg
2281 ctcgcagcca tgcgcaacca gagcaaccgc atcgtggacg tgctggagat gcgccccaac
2341 gacgcctccg accgcgtgac tgccgtgccc acccagttcc acttccactc cacctcggag
2401 cacctgctgg cgggtgcgtg ggcgtggtcg taactcgtga cttctgacag ggccaggtgt
2461 tgggaggggt gtttcaagca ttcggctccc ataaagcgat aaggtcccac caggtatcaa
2521 gcaagcacct gccttccgcg tgtcataaaa catccgctgg tgtcctcctt cgttacgtct
2581 accgcctgca ggcaagatct ttcctcttga gttgcacatt gtgcacaagg tgactgacaa
2641 gctagaggcc tgcaagggcg gctgcttcag cgtcaccggc atcctgttcc agctcgacaa
2701 cggccccgat aacgagctgc ttgagcgtga gtcgggcagc agaggcgggg cggtggaggc
2761 ggggcggggg cgggtttgtg cgaagctgtc acagtttgtg tggaatcggt acgcacgtgc
2821 atgccttatg agcgcttctc aggaggaccg ctgagcgctt ctcaggaggt gcctgatcca
2881 gtgcctctat ttcatcctct gttgtgccct tacatgctcg tttgcacgtt gactgatctc
2941 cacacttcat cgacccgtcc tctgcagcca tctttgcgaa catgcccacg cgcgagggca
3001 ccttcaccaa cctgccggcg ggcaccacca tcaagctggg tgagctgctg cccagcgacc
3061 gcgactacgt cacctacgag ggcagcctca ccaccccgcc ctgcagcgag ggcctgctgt
3121 ggcacgtcat gacccagccg cagcgcatca gcttcggcca gtggaaccgc taccgcctgg
3181 ctgtgggcga gaaggagtgc aactccacgg aggtaagata tgggggcgac agctgtgggg
3241 acgcaggctc gcaggtttgg aggagccctt cagggatttg ctccattatt ggttgggcga
3301 gcctttgcgt gagggcgcgc accttgccgc ctctgggtcc gcacacgcct ttctggtacc
3361 cagggttgtt cccggctaaa cgcaacgctg tgtccatctc atcattgcta cagaccgatg
3421 ctgcccacgc ggacgccggc catcatcacc accaccaccg ccgcctgctg cacaaccacg
3481 cgcacctgga ggaggtgcct gccgccacct ccgagcccaa gcactacttc cgccgcgtga
3541 tggaggagac cgagaacccc gatgcttgtg agtacgcacc gtgacgcaat gcgcacatac
3601 agtagccctg cacggaagct aagatagcta accccatcga cacgggttgc tctgatccga
3661 cctacgatcc ggcctgcatg ccccctgcct gcctctctcc tcccgcgcga cagacacctg
3721 cacgaccgtt gcctttggcc agaacttccg caacgcccag tacgccaacg gccgcaccat
3781 caagctggcc cgctacgagt aagacaggat tggcagaatt cgaaactact atgtgagcac
3841 tgttcgcgcg cgtatgacac tggtcgtgga cgagaggaag agcgcctgcg gcgctaaaag
3901 ctttagcacg gaactgaagc ataacacacg aggtcgggtt atcgtactga actcggaagg
3961 gcgaggccgc ttacactgcc ggaaggtagt tggcctcgtg actgtgaatg gtagcaaatc
4021 gagtgaggtt tttttttgta ggtcggatgc gttgcggatg gatcaaggag gatcaaggtg
4081 gggttgattg tgaggggttg ataagtacac cgggaacccc gaaggcagga gcggggagcc
4141 gatggcggcg gtggcagatg ctttccagcg tactgaataa tggctgccct gcctggaggt
4201 tttgagcgag tgcagttgat accttttttg aggtagttgt ggcgccttgg catggttttg
4261 ccgccggcaa cggccctgcc tttggccgtg cgtggtgctt gagggctgac cccatccacg
4321 gcccatgggt gatcagggca tcaagtttcg tgccccgcac cgccacatca cgcaataaac
4381 gcgttgatct tcccatatac tgtttgacat cggttttcag gtcgatgcta actaatttca
4441 cggctgagtc acacaatgct cgtgaccatt tatgcggcga tggatggcgg ggtgacagtg
4501 cagagccgta ggcccgtagc gcattatgtc gttggaggcg gtgtgtcaga cttcaaatcg
4561 gactcgaact cgcgacgtga atgatgcgtg tgagcttcac aggcgttgta gctttgtgca
4621 tggtgtacga gtggctgcaa gagagcacag ctgcttaggg cgtgtaagta tcaccggtac
4681 tgacacatca cccagcctga cctcgctgcc ccagagagcc cacacaaccc atgagcgcag
4741 caccggcagg cacctcctgg cacaacccat gagcgcaggt tgtgatcgcc agtgttgccg
4801 ctgccagtgc gctcatctcg tgccgtggtg cgcccgcatc aaccaggagc gtagggcc
//