GenBank-Updates@genbank.bio.net (02/08/91)
LOCUS HUMTLI309 520 bp ss-mRNA PRI 08-FEB-1991
DEFINITION Human secreted protein (I-309) mRNA, complete cds.
ACCESSION M57502
KEYWORDS secreted protein.
SOURCE Human T-cell, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 520)
AUTHORS Miller,M.D., Hata,S., de Waal Malefyt,R. and Krangel,M.S.
TITLE A novel polypeptide secreted by activated human T lymphocytes
JOURNAL J. Immunol. 143, 2907-2916 (1989)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA <1..520
/gene="I-309"
CDS 51..341
/gene="I-309"
/codon_start=51
/product="secreted protein I-309"
BASE COUNT 140 a 137 c 122 g 121 t
ORIGIN
1 accaggctca tcaaagctgc tccaggaagg cccaagccag accagaagac atgcagatca
61 tcaccacagc cctggtgtgc ttgctgctag ctgggatgtg gccggaagat gtggacagca
121 agagcatgca ggtacccttc tccagatgtt gcttctcatt tgcggagcaa gagattcccc
181 tgagggcaat cctgtgttac agaaatacca gctccatctg ctccaatgag ggcttaatat
241 tcaagctgaa gagaggcaaa gaggcctgcg ccttggacac agttggatgg gttcagaggc
301 acagaaaaat gctgaggcac tgcccgtcaa aaagaaaatg agcagatttc tttccattgt
361 gggctctgga aaccacatgg cttcacctgt ccccgaaact accagcccta caccattcct
421 tctgccctgc ttttgctagg tcacagagga tctgcttggt cttgataagc tatgttgttg
481 cactttaaac atttaaatta tacaatcatc aacccccaac
//GenBank-Updates@genbank.bio.net (02/12/91)
LOCUS HUMI309 3709 bp ds-DNA PRI 12-FEB-1991
DEFINITION Human secreted protein (I-309) gene, complete cds.
ACCESSION M57506
KEYWORDS secreted protein.
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3709)
AUTHORS Miller,M.D., Wilson,S.D., Dorf,M.E., Seuanez,H.N., O'Brien,S.J. and
Krangel,M.S.
TITLE Sequence and chromosomal location of the I-309 gene: Relationship
to genes encoding a family of inflammatory cytokines
JOURNAL J. Immunol. 145, 2737-2744 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(813..960,2149..2260,
3383..3664)
/gene="I-309"
/partial
CDS join(885..960,2149..2260,
3383..3485)
/gene="I-309"
/codon_start=1
/product="secreted protein I-309"
exon 813..960
/number=1
/gene="I-309"
/evidence=EXPERIMENTAL
/codon_start=1
exon 2149..2260
/number=2
/gene="I-309"
/codon_start=1
exon 3383..3664
/number=3
/gene="I-309"
/codon_start=1
BASE COUNT 984 a 857 c 948 g 920 t
ORIGIN Chromosome 17.
1 tctagaaaaa aaaaaacaaa aagggaaaat tcccctggca ggactctcag atgctgctga
61 gtagctctca gtcctctctg taacccaaac ataacacatc tatctccgtg cttacactgg
121 gtggctttca cttgtttatc tgtgaattga agagaagttg cttgaggtca ggcagtgctc
181 ctcattggta actgccttct ctggggctaa ccaaggacct agaacagaat aagctattga
241 aaattgttga ggattgaaaa aaatagaaaa aatagaaatg gcaaatatct aggccagtca
301 ctggacatag agaatgttat ttaattctta tcgcacgtcc ttgagacatg tattgctatt
361 tgcattttgt gtgaatatgc atttgggtaa gtttatgtaa tccctcctct gcagaactgg
421 gattcaaatg caggtgtatc tctgttcagg tccagactct tctgccctga agcagtagta
481 cttggatgga atgacgtagg gttggacaag ccacacagag gccacttcct ctcacttact
541 tttctttgct tcccactcaa ccaggacagt tcccacgcac tttttcaaga ttcttatctg
601 ctcccacact tggggaagtt cccaatgcaa cctatcaatc catcaccacc acgaatacca
661 gccaggagag gtggggaaag gagtttacca catggtcgct gggtgtgagc aactgttccc
721 tgtccctatg gcttcccact tgtggctccc accatggcct ggagttttgg gtggagtttt
781 tcaaataaaa gccctcagca ttgcaggacg gcacagtggt gagctcttag cttcaccagg
841 ctcatcaaag ctgctccagg aaggcccaag ccagaccaga agacatgcag atcatcacca
901 cagccctggt gtgcttgctg ctagctggga tgtggccgga agatgtggac agcaagagca
961 gtgagtgtgg caggcatcat tttgcttctc tctggggagg gcagaaacgt ggtcagccac
1021 tctggggttg gagcaggctt ctccttgaac tcaccaactc tatctcccct cttcctacct
1081 aaagaggagg aatggtgaac ttggacaggc tggggtgagg gctagtagga gaaccatgag
1141 ttggggcaaa cacagagaac tgaactgaca gcttcagtac aaggagctct gcttcatcca
1201 gacccaagga agggaacctg tgaggttact cgggtaaagc tgggaggccc aaggtccagg
1261 ggacagcctg ggtgtagctt ctacagtgtg acagacacca agtagagtca gaaggcaaga
1321 ccgggctcta acaattggtc actcttgggc aagtcacttt agctctcaaa ctctactttc
1381 tctatcagtg aaatggagtt gatgatgtct gccctccaag actgtttgga gaataccaac
1441 ctagtaagag gcatgaaagg gggtgcaaac agaaaaacta ggaggaagaa gctgggattg
1501 gaatgcaggt ctcttgcggg atgtggtgtg ggaggagaat gcacaaatgg acagagtggg
1561 ggttgggggc tgggaaagag ctaaggacca gggcaggagg ggattcaaga gactgagtag
1621 ggcagctagc tagttcctgg gagctcttcc cttgtcatct catcagtttg gactcctcga
1681 acaattccta atcttcccca gatcaggtct gtgaactgtg gaccactgtg tcctgcatca
1741 gactaaccag gtccccaggg tgtggggtcc agagcccttg gacatgaata ctggggcaga
1801 accatgcaca tgtggtgaaa taccaaaact ggatgagcct ttagaaacca ggctccaaaa
1861 agttttattt tacagatggg aagtctgggg ccagggtgaa ggcacatctt cctcagggcc
1921 actcagctgg ggtgcgggga gctcagatct gaaccccaat cttctgactc tttacctagc
1981 cccagaacaa ggtggctgat gaggcagagc tatgccggca ccgtctggat gtggtcccca
2041 agccagggct tgtcctggga ggcgtttttt tgtttgtttt ttaaaaattg tgctacaggt
2101 gagaggttga gaaatggatg caaaccatcg tctgtgttcc tcttctagtg caggtaccct
2161 tctccagatg ttgcttctca tttgcggagc aagagattcc cctgagggca atcctgtgtt
2221 acagaaatac cagctccatc tgctccaatg agggcttaat gtaagtgatc acctgctcaa
2281 tctctcccta gagaacagaa ccccgccagc ctggaattac aagagtagac actagatgac
2341 agtattttac tggaataagg tttctaaacc cagagctgcc agcacctggg tgcaagccac
2401 acttgggcgc tagagggagc gctgagcttc ctagcaggtg tgaggaagga tgcatctgtg
2461 ctcctgcagt ggcttgtgtt tcctgaaact ccaaggtgcc aagtattgta tcccagcatt
2521 atgagctcag aggtttaaca aaagcatgag gggttattgt gcactggaaa gagcaaggga
2581 accaggatga gttcctgccc ctggatttgg aacccatagt cttgggtgac cgtggacagg
2641 taactccttt gtactgaatt gtctgtgtat ccttctgtat tccttatctg tgaagggtca
2701 taaacatagc tgcatcacag ggtctttaca aacttaattg gagtagcttt cacataccag
2761 tcagtatttt aaggcttttt catgtatatt ctctctgtcg atcctcttgg ggcacatatt
2821 tttgttatca tgaaaagtga ggttcaggaa ggtagagata tttgtctaag atcaaccaga
2881 tagtaagaga tagagttggt ctatagattg gacaatagtc cagtttagga agtagacaga
2941 tcagaagaga aaaatacaca cccacacaca cacacaaggc gcgcgcacac acacacacac
3001 aaacacatga gtccaacgca acaagtaagg ccccagatgg acacagaaac attaaagttg
3061 gtgcaaagag ctattccagg atgggaattt ctcatctcac ctaatcgtca gaatgttttc
3121 agctgttcag ccccaccctg atacaccaaa ttgaaaccag gagaggggtc caggaaattc
3181 aattcataag ctcctggtgc tttggctgtt ccccagcgtg caaaccacac atcctgtgca
3241 gcaacttcat ttacagaggg gagcccaagg cctagcaaga gcagtttagg ggacctggca
3301 gccggaggag gcggggcttg tgcgttgccc acccagtggt ggcttgggtg gctcagcctt
3361 ctctcttatt ctctgttcac agattcaagc tgaagagagg caaagaggcc tgcgccttgg
3421 acacagttgg atgggttcag aggcacagaa aaatgctgag gcactgcccg tcaaaaagaa
3481 aatgagcaga tttctttcca ttgtgggctc tggaaaccac atggcttcac ctgtccccga
3541 aactaccagc cctacaccat tccttctgcc ctgcttttgc taggtcacag aggatctgct
3601 tggtcttgat aagctatgtt gttgcacttt aaacatttaa attatacaat catcaacccc
3661 caaccctctg ggctcttgga tttcagagtg aaaacttgat ggcattgag
//GenBank-Updates@genbank.bio.net (02/23/91)
LOCUS HUMI309 3709 bp ds-DNA PRI 22-FEB-1991
DEFINITION Human secreted protein (I-309) gene, complete cds.
ACCESSION M57506
KEYWORDS secreted protein.
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3709)
AUTHORS Miller,M.D., Wilson,S.D., Dorf,M.E., Seuanez,H.N., O'Brien,S.J. and
Krangel,M.S.
TITLE Sequence and chromosomal location of the I-309 gene: Relationship
to genes encoding a family of inflammatory cytokines
JOURNAL J. Immunol. 145, 2737-2744 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(813..960,2149..2260,3383..3664)
/gene="I-309"
/partial
CDS join(885..960,2149..2260,3383..3485)
/product="secreted protein I-309"
/gene="I-309"
/codon_start=885
exon 813..960
/number=1
/gene="I-309"
/evidence=EXPERIMENTAL
exon 2149..2260
/number=2
/gene="I-309"
exon 3383..3664
/number=3
/gene="I-309"
BASE COUNT 984 a 857 c 948 g 920 t
ORIGIN Chromosome 17.
1 tctagaaaaa aaaaaacaaa aagggaaaat tcccctggca ggactctcag atgctgctga
61 gtagctctca gtcctctctg taacccaaac ataacacatc tatctccgtg cttacactgg
121 gtggctttca cttgtttatc tgtgaattga agagaagttg cttgaggtca ggcagtgctc
181 ctcattggta actgccttct ctggggctaa ccaaggacct agaacagaat aagctattga
241 aaattgttga ggattgaaaa aaatagaaaa aatagaaatg gcaaatatct aggccagtca
301 ctggacatag agaatgttat ttaattctta tcgcacgtcc ttgagacatg tattgctatt
361 tgcattttgt gtgaatatgc atttgggtaa gtttatgtaa tccctcctct gcagaactgg
421 gattcaaatg caggtgtatc tctgttcagg tccagactct tctgccctga agcagtagta
481 cttggatgga atgacgtagg gttggacaag ccacacagag gccacttcct ctcacttact
541 tttctttgct tcccactcaa ccaggacagt tcccacgcac tttttcaaga ttcttatctg
601 ctcccacact tggggaagtt cccaatgcaa cctatcaatc catcaccacc acgaatacca
661 gccaggagag gtggggaaag gagtttacca catggtcgct gggtgtgagc aactgttccc
721 tgtccctatg gcttcccact tgtggctccc accatggcct ggagttttgg gtggagtttt
781 tcaaataaaa gccctcagca ttgcaggacg gcacagtggt gagctcttag cttcaccagg
841 ctcatcaaag ctgctccagg aaggcccaag ccagaccaga agacatgcag atcatcacca
901 cagccctggt gtgcttgctg ctagctggga tgtggccgga agatgtggac agcaagagca
961 gtgagtgtgg caggcatcat tttgcttctc tctggggagg gcagaaacgt ggtcagccac
1021 tctggggttg gagcaggctt ctccttgaac tcaccaactc tatctcccct cttcctacct
1081 aaagaggagg aatggtgaac ttggacaggc tggggtgagg gctagtagga gaaccatgag
1141 ttggggcaaa cacagagaac tgaactgaca gcttcagtac aaggagctct gcttcatcca
1201 gacccaagga agggaacctg tgaggttact cgggtaaagc tgggaggccc aaggtccagg
1261 ggacagcctg ggtgtagctt ctacagtgtg acagacacca agtagagtca gaaggcaaga
1321 ccgggctcta acaattggtc actcttgggc aagtcacttt agctctcaaa ctctactttc
1381 tctatcagtg aaatggagtt gatgatgtct gccctccaag actgtttgga gaataccaac
1441 ctagtaagag gcatgaaagg gggtgcaaac agaaaaacta ggaggaagaa gctgggattg
1501 gaatgcaggt ctcttgcggg atgtggtgtg ggaggagaat gcacaaatgg acagagtggg
1561 ggttgggggc tgggaaagag ctaaggacca gggcaggagg ggattcaaga gactgagtag
1621 ggcagctagc tagttcctgg gagctcttcc cttgtcatct catcagtttg gactcctcga
1681 acaattccta atcttcccca gatcaggtct gtgaactgtg gaccactgtg tcctgcatca
1741 gactaaccag gtccccaggg tgtggggtcc agagcccttg gacatgaata ctggggcaga
1801 accatgcaca tgtggtgaaa taccaaaact ggatgagcct ttagaaacca ggctccaaaa
1861 agttttattt tacagatggg aagtctgggg ccagggtgaa ggcacatctt cctcagggcc
1921 actcagctgg ggtgcgggga gctcagatct gaaccccaat cttctgactc tttacctagc
1981 cccagaacaa ggtggctgat gaggcagagc tatgccggca ccgtctggat gtggtcccca
2041 agccagggct tgtcctggga ggcgtttttt tgtttgtttt ttaaaaattg tgctacaggt
2101 gagaggttga gaaatggatg caaaccatcg tctgtgttcc tcttctagtg caggtaccct
2161 tctccagatg ttgcttctca tttgcggagc aagagattcc cctgagggca atcctgtgtt
2221 acagaaatac cagctccatc tgctccaatg agggcttaat gtaagtgatc acctgctcaa
2281 tctctcccta gagaacagaa ccccgccagc ctggaattac aagagtagac actagatgac
2341 agtattttac tggaataagg tttctaaacc cagagctgcc agcacctggg tgcaagccac
2401 acttgggcgc tagagggagc gctgagcttc ctagcaggtg tgaggaagga tgcatctgtg
2461 ctcctgcagt ggcttgtgtt tcctgaaact ccaaggtgcc aagtattgta tcccagcatt
2521 atgagctcag aggtttaaca aaagcatgag gggttattgt gcactggaaa gagcaaggga
2581 accaggatga gttcctgccc ctggatttgg aacccatagt cttgggtgac cgtggacagg
2641 taactccttt gtactgaatt gtctgtgtat ccttctgtat tccttatctg tgaagggtca
2701 taaacatagc tgcatcacag ggtctttaca aacttaattg gagtagcttt cacataccag
2761 tcagtatttt aaggcttttt catgtatatt ctctctgtcg atcctcttgg ggcacatatt
2821 tttgttatca tgaaaagtga ggttcaggaa ggtagagata tttgtctaag atcaaccaga
2881 tagtaagaga tagagttggt ctatagattg gacaatagtc cagtttagga agtagacaga
2941 tcagaagaga aaaatacaca cccacacaca cacacaaggc gcgcgcacac acacacacac
3001 aaacacatga gtccaacgca acaagtaagg ccccagatgg acacagaaac attaaagttg
3061 gtgcaaagag ctattccagg atgggaattt ctcatctcac ctaatcgtca gaatgttttc
3121 agctgttcag ccccaccctg atacaccaaa ttgaaaccag gagaggggtc caggaaattc
3181 aattcataag ctcctggtgc tttggctgtt ccccagcgtg caaaccacac atcctgtgca
3241 gcaacttcat ttacagaggg gagcccaagg cctagcaaga gcagtttagg ggacctggca
3301 gccggaggag gcggggcttg tgcgttgccc acccagtggt ggcttgggtg gctcagcctt
3361 ctctcttatt ctctgttcac agattcaagc tgaagagagg caaagaggcc tgcgccttgg
3421 acacagttgg atgggttcag aggcacagaa aaatgctgag gcactgcccg tcaaaaagaa
3481 aatgagcaga tttctttcca ttgtgggctc tggaaaccac atggcttcac ctgtccccga
3541 aactaccagc cctacaccat tccttctgcc ctgcttttgc taggtcacag aggatctgct
3601 tggtcttgat aagctatgtt gttgcacttt aaacatttaa attatacaat catcaacccc
3661 caaccctctg ggctcttgga tttcagagtg aaaacttgat ggcattgag
//