GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMMACT 1518 bp ss-mRNA PRI 21-FEB-1991
DEFINITION Human acetyl-CoA acetyltransferase mRNA.
ACCESSION D90228 M61117
KEYWORDS acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase.
SOURCE Human liver, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1518)
AUTHORS Fukao,T., Yamaguchi,S., Kano,M., Orii,T., Fujiki,Y., Osumi,T. and
Hashimoto,T.
TITLE Molecular cloning and sequence of the complementary DNA encoding
human mitochondrial acetoacetyl-Coenzyme A thiolase and study of
the variant enzymes in cultured fibroblasts from patients with
3-ketothiolase deficiency
JOURNAL J. Clin. Invest. 86, 2086-2092 (1990)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by: Toshiuki
Fukao Department of Pediatrics Gifu University School of Medicine
40 Tsukasa-machi Gifu 500 Japan Phone: 0582-65-1241 Fax:
0582-65-9011
FEATURES Location/Qualifiers
CDS 77..1360
/note="mitochondrial acetyl-CoA acetyltransferase (EC
2.3.1.9) precursor"
sig_peptide 77..174
/note="mitochondrial acetyl-CoA acetyltransferase signal
peptide"
mat_peptide 175..1357
/note="mitochondrial acetyl-CoA acetyltransferase"
BASE COUNT 454 a 283 c 390 g 391 t
ORIGIN
1 aggccgctag ggtgcggggt tggggaggag gccgctagtc tacgcctgtg gagccgatac
61 tcagccctct gcgaccatgg ctgtgctggc ggcacttctg cgcagcggcg cccgcagccg
121 cagccccctg ctccggaggc tggtgcagga aataagatat gtggaacgga gttatgtatc
181 aaaacccact ttgaaggaag tggtcatagt aagtgctaca agaacaccca ttggatcttt
241 tttaggcagc ctttccttgc tgccagccac taagcttggt tccattgcaa ttcagggagc
301 cattgaaaag gcagggattc caaaagaaga agtgaaagaa gcatacatgg gtaatgttct
361 acaaggaggt gaaggacaag ctcctacaag gcaggcagta ttgggtgcag gcttacctat
421 ttctactcca tgtaccacca taaacaaagt ttgtgcttca ggaatgaaag ccatcatgat
481 ggcctctcaa agtcttatgt gtggacatca ggatgtgatg gtggcaggtg ggatggagag
541 catgtccaat gttccatatg taatgaacag aggatcaaca ccatatggtg gggtaaagct
601 tgaagatttg attgtaaaag acgggctaac tgatgtctac aataaaattc atatgggcag
661 ctgtgctgag aatacagcaa agaagctgaa tattgcacga aatgaacagg acgcttatgc
721 tattaattct tataccagaa gtaaagcagc atgggaagct gggaaatttg gaaatgaagt
781 tattcctgtc acagttacag taaaaggtca accagatgta gtggtgaaag aagatgaaga
841 atataaacgt gttgatttta gcaaagttcc aaagctgaag acagttttcc agaaagaaaa
901 tggcacagta acagctgcca atgccagtac actgaatgat ggagcagctg ctctggttct
961 catgacggca gatgcagcga agaggctcaa tgttacacca ctggcaagaa tagtagcatt
1021 tgctgacgct gctgtagaac ctattgattt tccaattgct cctgtatatg ctgcatctat
1081 ggttcttaaa gatgtgggat tgaaaaaaga agatattgca atgtgggaag taaatgaagc
1141 ctttagtctg gttgtactag caaacattaa aatgttggag attgatcccc aaaaagtgaa
1201 tatcaatgga ggagctgttt ctctgggaca tccaattggg atgtctggag ccaggattgt
1261 tggtcatttg actcatgcct tgaagcaagg agaatacggt cttgccagta tttgcaatgg
1321 aggaggaggt gcttctgcca tgctaattca gaagctgtag acaacctctg ctatttaagg
1381 agacaaccct atgtgaccag aaggcctgct gtaatcagtg tgactactgt gggtcagctt
1441 atattcagat aagctgtttc attttttatt attttctatg ttaactttta aaaatcaaaa
1501 tgatgaaatc ccaaaaca
//GenBank-Updates@genbank.bio.net (02/23/91)
LOCUS HUMMACT 1518 bp ss-mRNA PRI 23-FEB-1991
DEFINITION Human acetyl-CoA acetyltransferase mRNA.
ACCESSION D90228 M61117
KEYWORDS acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase.
SOURCE Human liver, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1518)
AUTHORS Fukao,T., Yamaguchi,S., Kano,M., Orii,T., Fujiki,Y., Osumi,T. and
Hashimoto,T.
TITLE Molecular cloning and sequence of the complementary DNA encoding
human mitochondrial acetoacetyl-Coenzyme A thiolase and study of
the variant enzymes in cultured fibroblasts from patients with
3-ketothiolase deficiency
JOURNAL J. Clin. Invest. 86, 2086-2092 (1990)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by:
Toshiyuki
Fukao Department of Pediatrics Gifu University School of Medicine
40 Tsukasa-machi Gifu 500 Japan Phone: 0582-65-1241 Fax:
0582-65-9011
FEATURES Location/Qualifiers
CDS 77..1360
/note="mitochondrial acetyl-CoA acetyltransferase (EC
2.3.1.9) precursor"
sig_peptide 77..175
/note="mitochondrial acetyl-CoA acetyltransferase signal
peptide"
mat_peptide 176..1357
/note="mitochondrial acetyl-CoA acetyltransferase"
misc_feature 452..454
/note="put. active site (Cys)"
BASE COUNT 454 a 283 c 390 g 391 t
ORIGIN
1 aggccgctag ggtgcggggt tggggaggag gccgctagtc tacgcctgtg gagccgatac
61 tcagccctct gcgaccatgg ctgtgctggc ggcacttctg cgcagcggcg cccgcagccg
121 cagccccctg ctccggaggc tggtgcagga aataagatat gtggaacgga gttatgtatc
181 aaaacccact ttgaaggaag tggtcatagt aagtgctaca agaacaccca ttggatcttt
241 tttaggcagc ctttccttgc tgccagccac taagcttggt tccattgcaa ttcagggagc
301 cattgaaaag gcagggattc caaaagaaga agtgaaagaa gcatacatgg gtaatgttct
361 acaaggaggt gaaggacaag ctcctacaag gcaggcagta ttgggtgcag gcttacctat
421 ttctactcca tgtaccacca taaacaaagt ttgtgcttca ggaatgaaag ccatcatgat
481 ggcctctcaa agtcttatgt gtggacatca ggatgtgatg gtggcaggtg ggatggagag
541 catgtccaat gttccatatg taatgaacag aggatcaaca ccatatggtg gggtaaagct
601 tgaagatttg attgtaaaag acgggctaac tgatgtctac aataaaattc atatgggcag
661 ctgtgctgag aatacagcaa agaagctgaa tattgcacga aatgaacagg acgcttatgc
721 tattaattct tataccagaa gtaaagcagc atgggaagct gggaaatttg gaaatgaagt
781 tattcctgtc acagttacag taaaaggtca accagatgta gtggtgaaag aagatgaaga
841 atataaacgt gttgatttta gcaaagttcc aaagctgaag acagttttcc agaaagaaaa
901 tggcacagta acagctgcca atgccagtac actgaatgat ggagcagctg ctctggttct
961 catgacggca gatgcagcga agaggctcaa tgttacacca ctggcaagaa tagtagcatt
1021 tgctgacgct gctgtagaac ctattgattt tccaattgct cctgtatatg ctgcatctat
1081 ggttcttaaa gatgtgggat tgaaaaaaga agatattgca atgtgggaag taaatgaagc
1141 ctttagtctg gttgtactag caaacattaa aatgttggag attgatcccc aaaaagtgaa
1201 tatcaatgga ggagctgttt ctctgggaca tccaattggg atgtctggag ccaggattgt
1261 tggtcatttg actcatgcct tgaagcaagg agaatacggt cttgccagta tttgcaatgg
1321 aggaggaggt gcttctgcca tgctaattca gaagctgtag acaacctctg ctatttaagg
1381 agacaaccct atgtgaccag aaggcctgct gtaatcagtg tgactactgt gggtcagctt
1441 atattcagat aagctgtttc attttttatt attttctatg ttaactttta aaaatcaaaa
1501 tgatgaaatc ccaaaaca
//