GenBank-Updates@genbank.bio.net (02/23/91)
LOCUS JEVSAA 10976 bp ss-RNA VRL 23-FEB-1991 DEFINITION Japanese encephalitis virus strain SA(A), complete genome. ACCESSION D90195 KEYWORDS complete genome; pathogenesis; polyprotein; viral attenuation. SOURCE Japanese encephalitis virus (strain SA14-14-2), cDNA to viral RNA. ORGANISM Japanese encephalitis virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Flaviviridae; Flavivirus (arbovirus group B). REFERENCE 1 (bases 1 to 10976) AUTHORS Aihara,S., Rao,C., Yu,Y.X., Lee,T., Watanabe,K., Komiya,T., Sumiyoshi,H., Hashimoto,H. and Nomoto,A. TITLE Identification of mutations occurred on the genome of Japanese encephalitis virus during the attenuation process JOURNAL Unpublished (1990) STANDARD full staff_entry COMMENT These data kindly submitted in computer readable form by: Akio Nomoto The Tokyo Metropolitan Institute of Medical Science Honkomagome, Bunkyo-ku Tokyo 113 Japan Phone: 03-823-2101 x5267 Fax: 03-828-8945 FEATURES Location/Qualifiers CDS 96..10394 /note="polyprotein" BASE COUNT 3035 a 2516 c 3117 g 2308 t ORIGIN 1 agaagtttat ctgtgtgaac ttcttggctt agtatcgtag agaagaatcg agagattagt 61 gcagtttaaa cagtttttta gaacggaaga taaccatgac taaaaaacca ggagggcccg 121 gtaaaaaccg ggctatcaat atgctgaaac gcggcctacc ccgcgtattc ccactagtgg 181 gagtgaagag ggtagtaatg agcttgttgg acggcagagg gccagtacgt ttcgtgctgg 241 ctcttatcac gttcttcaag tttacagcat tagccccgac caaggcgctt tcaggccgat 301 ggaaagcagt ggaaaagagt gtggcaatga aacatcttac tagtttcaaa cgagaacttg 361 gaacactcat tgacgccgtg aacaagcggg gcagaaagca aaacaaaaga ggaggaaatg 421 aaggctcaat catgtggctc gcgagcttgg cagttgtcat agcttgtgca ggagccatga 481 agttgtcgaa tttccagggg aagcttttga tgaccatcaa caacacggac attgcagacg 541 ttatcgtgat tcccacctca aaaggagaga acagatgctg ggtccgggca atcgacgtcg 601 gctacatgtg tgaggacact atcacgtacg aatgtcctaa gcttaccatg ggcaatgatc 661 cagaggatgt ggattgctgg tgtgacaacc aagaagtcta cgtccaatat ggacggtgca 721 cgcggaccag gcattccaag cgaagcagga gatccgtgtc ggtccaaaca catggggaga 781 gttcactagt gaataaaaaa gaggcttggc tggattcaac gaaagccaca cgatatctca 841 tgaaaactga gaactggatc ataaggaatc ctggctatgc tttcctggcg gcggtacttg 901 gctggatgct tggcagtaac aacggtcaac gcgtggtatt taccatcctc ctgctgttgg 961 tcgctccggc ttacagtttt aattgtctgg gaatgggcaa tcgtgacttc atagaaggag 1021 ccagtggagc cacttgggtg gacttggtgc tagaaggaga cagctgcttg acaatcatgg 1081 caaacgacaa accaacattg gacgtccgca tgattaacat cgaagctagc caacttgctg 1141 aggtcagaag ttactgctat catgcttcag tcactgacat ctcgacggtg gctcggtgcc 1201 ccacgactgg agaagcccac aacgagaagc gagctgatag tagctatgtg tgcaaacaag 1261 gcttcactga ccgtgggtgg ggcaacggat gtggattttt cgggaaggga agcattgaca 1321 catgtgcaaa attctcctgc accagtaaag cgattgggag aacaatccag ccagaaaaca 1381 tcaaatacaa agttggcatt tttgtgcatg gaaccaccac ttcggaaaac catgggaatt 1441 attcagcgca agttggggcg tcccaggcgg caaagtttac agtaacaccc aatgctcctt 1501 cggtagccct caaacttggt gactacggag aagtcacact ggactgtgag ccaaggagtg 1561 gactgaacac tgaagcgttt tacgtcatga ccgtggggtc aaagtcattt ctggtccata 1621 gggagtggtt tcatgacctc gctctcccct ggacgtcccc ttcgagcaca gcgtggagaa 1681 acagagaact cctcatggaa tttgaagggg cgcacgccac aaaacagtcc gttgttgctc 1741 ttgggtcaca ggaaggaggc ctccatcatg cgttggcagg agccatcgtg gtggagtact 1801 caagctcagt gatgttaaca tcaggccacc tgaaatgtag gctgaaaatg gacaaactgg 1861 ctctgaaagg cacaacctat ggcatgtgta cagaaaaatt ctcgttcgcg aaaaatccgg 1921 tggacactgg tcacggaaca gttgtcattg aactctccta ctctgggagt gatggcccct 1981 gcaaaattcc gattgtttcc gttgcgagcc tcaatgacat gacccccgtt gggcggctgg 2041 tgacagtgaa ccccttcgtc gcgacttcca gtgccaactc aaaggtgctg gtcgagatgg 2101 aacccccctt cggagactcc tacatcgtag ttggaagggg agacaagcag atcaaccacc 2161 attggcacaa agctggaagc acgctgggca aggccttttc aacaactttg aagggagctc 2221 aaagactggc agcgttgggc gacacagcct gggactttgg ctctattgga ggggtcttca 2281 actccatagg aagagccgtt caccaagtgt ttggtggtgc cttcagaaca ctctttgggg 2341 gaatgtcttg gatcacacaa gggctaatgg gtgccctact gctctggatg ggcgtcaacg 2401 cacgagaccg atcaattgct ttggccttct tagccacagg aggtgtgctc gtgttcttag 2461 cgaccaatgt gcatgctgac actggatgtg ccattgacat cacaagaaaa gagatgagat 2521 gtggaagtgg catcttcgtg cacaacgacg tggaagcctg ggtggatagg tataaatatt 2581 tgccagaaac gcccagatcc ctagcgaaga tcgtccacaa agcgcacaag gaaggcgtgt 2641 gcggagtcag atctgtcact agactggagc accaaatgtg ggaagccgta agggacgaat 2701 tgaacgtcct gctcaaagag aatgcagtgg acctcagtgt ggttgtgaac aagcccgtgg 2761 gaagatatcg ctcagcccct aaacgcctat ccatgacgca agagaagttt gaaatgggct 2821 ggaaagcatg gggaaaaagc atcctctttg ccccggaatt ggctaactcc acatttgtcg 2881 tagatggacc tgagacaaag gaatgccctg atgagcacag agcttggaac agcatgcaaa 2941 tcgaagactt cggctttggc atcacatcaa cccgtgtgtg gctgaaaatt agagaggaga 3001 gcactgacga gtgtgatgga gcgatcatag gcacggctgt caaaggacat gtggcagtcc 3061 atagtgactt gtcgtactgg attgagagtc gctacaacga cacatggaaa cttgagaggg 3121 cagtctttgg agaggtcaaa tcttgcactt ggccagagac acacaccctt tggggagatg 3181 atgttgagga aagtgaactc atcattccgc acaccatagc cggaccaaaa agcaagcaca 3241 atcggaggga agggtataag acacaaaacc agggaccttg ggatgagaat ggcatagtct 3301 tggactttga ttattgccca gggacaaaag tcaccattac agaggattgt agcaagagag 3361 gcccttcggt cagaaccact actgacagtg gaaagttgat cactgactgg tgctgtcgca 3421 gttgctccct tccgccccta cgattccgga cagaaaatgg ctgctggtac ggaatggaaa 3481 tcagacctgt tatgcatgat gaaacaacac tcgtcagatc acaggttcat gctttcaaag 3541 gtgaaatggt tgaccctttt cagctgggcc ttctggtgat gtttctggcc acccaggaag 3601 tccttcgcaa gaggtggacg gccagattga ccattcctgc ggttttgggg gtcctacttg 3661 tgctgatgct tgggggtatc acttacactg atttggcgag gtatgtggtg ctagtcgctg 3721 ctgctttcgc agaggccaac agtggaggag acgtcctgca ccttgctttg attgctgttt 3781 ttaagatcca accagcattt ttagtgatga acatgcttag cacgagatgg acgaaccaag 3841 aaaacgtggt tctggtccta ggggctgcct ttttccaatt ggcctcagta gatctgcaaa 3901 taggagtcca cggaatcctg aatgccgctg ctatagcatg gatgattgtc cgagcgatca 3961 ccttccccac aacctcctcc gtcaccatgc cagtcttagc gcttctaact ccggggatga 4021 gggctctata cctagacact tacagaatca tcctcctcgt catagggatt tgctccctgc 4081 tgcacgagag gaaaaagacc atggcgaaaa agaaaggagc tgtactcttg ggcttagcgc 4141 tcacatccac tggatggttc tcgcccacca ctatagctgc cggactaatg gtctgcaacc 4201 caaacaagaa gagagggtgg ccagctactg agtttttgtc ggcagttgga ttgatgtttg 4261 ccatcgtagg tggtttggcc gagttggata ttgaatccat gtcaataccc ttcatgctgg 4321 caggtctcat ggcagtgtcc tacgtggtgt caggaaaagc aacagatatg tggcttgaac 4381 gggccgccga catcagctgg gatatgggtg ctgcaatcac aggaagcagt cggaggctgg 4441 atgtgaaact ggatgatgac ggagattttc acttgattga tgatcccggt gttccatgga 4501 aggtctgggt cctgcgcatg tcttgcattg gcttagccgc cctcacgcct tgggccatcg 4561 ttcccgccgc tttcggttat tggctcactt taaaaacaac aaaaagaggg ggcgtgtttt 4621 gggacacgcc atccccaaaa ccttgctcaa aaggagacac cactacagga gtctaccgaa 4681 ttatggctag agggattctt ggcacttacc aggccggcgt cggagtcatg tacgagaatg 4741 ttttccacac actatggcac acaactagag gagcagccat tgtgagtgga gaaggaaaat 4801 tgacgccata ctggggtagt gtgaaagaag accgcatagc ttacggaggc ccatggaggt 4861 ttgaccgaaa atggaatgga acagatgacg tgcaagtgat cgtggtagaa ccggggaagg 4921 gcgcagtaaa catccagaca aaaccaggag tgtttcggac tcccttcggg gaggttgggg 4981 ctgttagtct ggattacccg cgaggaacat ccggctcacc cattctggat tccaatggag 5041 acattatagg cctatacggc aatggagttg agcttggcga tggctcatac gtcagcgcca 5101 tcgtgcaggg tgaccgtcag gaggaaccag tcccagaagc ttacacccca aacatgttga 5161 gaaagagaca gatgactgtg ctagatttgc accctggttc agggaaaacc aggaaaattc 5221 tgccacaaat aattaaggac gctatccagc agcgcctaag aacagctgtg ttggcaccga 5281 cgcgggtggt agcagcagaa atggcagaag ttttgagagg gctcccagta cgatatcaaa 5341 cttcagcagt gcagagagag caccaaggga atgaaatagt ggatgtgatg tgccacgcca 5401 ctctgaccca tagactgatg tcaccgaaca gagtgcccaa ctacaaccta tttgtcatgg 5461 atgaagctca tttcaccgac ccagccagta tagccgcacg aggatacatt gctaccaagg 5521 tggaattagg ggaggcagca gccatcttta tgacagcgac cccgcctgga accacggatc 5581 cttttcctga ctcaaatgcc ccaatccatg atttgcaaga tgagatacca gactgggcat 5641 ggagcagtgg atacgaatgg atcacagaat atgcgggtaa aaccgtgtgg tttgtggcga 5701 gcgtaaaaat ggggaatgag attgcaatgt gcctccaaag agcggggaaa aaggtcatcc 5761 aactcaaccg caagtcctat gacacagaat acccaaaatg taagaatgga gactgggatt 5821 ttgtcattac caccgacatc tctgaaatgg gggccaactt cggtgcgagc agggtcatcg 5881 actgtagaaa gagcgtgaaa cccaccatct tagaagaggg agaaggcaga gtcatcctcg 5941 gaaacccatc tcccataacc agtgcaagcg cagctcaacg gaggggcaga gtaggcagaa 6001 accccaatca agttggagat gaataccact atgggggggc taccagtgaa gatgacagta 6061 acctagccca ttggacagag gcaaagatca tgttagacaa catacacatg cccaatggac 6121 tggtggccca gctctatgga ccagagaggg aaaaggcttt cacaatggat ggcgaatacc 6181 gtctcagagg tgaagaaaag aaaaacttct tagagctgct taggacggct gacctcccgg 6241 tgtggctggc ctacaaggtg gcgtccaatg gcattcagta caccgacaga aagtggtgtt 6301 ttgatgggcc gcgtacgaat gccatactgg aggacaacac cgaggtagag atagtcaccc 6361 ggatgggtga gaggaaaatc ctcaagccga gatggcttga tgcaagagtt tatgcagatc 6421 accaggccct caagtggttc aaagactttg cagcagggaa gagatcagcc gttagcttca 6481 tagaggtgct cggtcgcatg cctgagcatt tcatgggaaa gacgcgggaa gctttagaca 6541 ccatgtactt ggttgcaacg gctgagaaag gtgggaaagc acaccgaatg gctctcgaag 6601 agctgccaga tgcactggaa accatcacac ttactgtcgc cattactgtg atgacaggag 6661 gattcttcct actaatgatg cagcgaaagg gtatagggaa gatgggtctt ggagctctag 6721 tgctcacact agctaccttc ttcctgtggg cggcagaggt tcctggaacc aaaatagcag 6781 ggaccctgct gatcgccctg ctgctgatgg tggttctcat cccagaaccg gaaaaacaga 6841 ggtcacagac agataaccaa ctggcggtgt ttctcatctg tgtcttgacc gtggttggag 6901 tggtggcagc aaacgagtac gggatgctag aaaaaaccaa agcggatctc aagagcatgt 6961 ttggcggaaa gacgcaggca tcaggactga ctggattgcc aagcatggca ctggacctgc 7021 gtccagccac agcctgggca ctgtatgggg ggagcacagt cgtgctaacc cctcttctga 7081 agcacctgat cacgtcggaa tacgtcacca catcgctagc ttcaattaac tcacaagctg 7141 gctcattatt cgtcttgcca cgaggcgtgc cttttaccga cctagacttg actgttggcc 7201 tcgtcttcct tggctgttgg ggtcaagtca ccctcacaac gtttctgaca gccatggttc 7261 tggcgacact tcactatggg tacatgctcc ctggatggca agcagaagca ctcagggctg 7321 cccagagaag gacagcggct ggaataatga agaatgccgt tgttgacgga atggtcgcca 7381 ctgatgtgcc tgaactggaa aggactactc ctctgatgca aaagaaagtc ggacaggtgc 7441 tcctcatagg ggtaagcgtg gcagcgttcc tcgtcaaccc taatgtcacc actgtgagag 7501 aagcaggggt gttggtgacg gcggctacgc ttactttgtg ggacaatgga gccagtgccg 7561 tttggaattc caccacagcc acgggactct gccatgtcat gcgaggtagc tacctggctg 7621 gaggctccat tgcttggact ctcatcaaga acgcggataa gccctccttg aaaaggggaa 7681 ggcctggggg caggacgcta ggggagcagt ggaaggaaaa actaaatgcc atgagtagag 7741 aagagttttt taaataccgg agagaggcca taatcgaggt ggaccgcact gaagcacgca 7801 gggccagacg tgaaaataac atagtgggag gacatccggt ttcgcgaggc tcagcaaaac 7861 tccgttggct cgtggagaaa ggatttgtct cgccaatagg aaaagtcatt gatctagggt 7921 gtgggcgtgg aggatggagc tactacgcag caaccctgaa gaaggtccag gaagtcagag 7981 gatacacgaa aggtggggcg ggacatgaag aaccgatgct catgcagagc tacggctgga 8041 acctggtctc cctgaagagt ggagtggacg tgttttacaa accttcagag cccagtgata 8101 ccctgttctg tgacataggg gaatcctccc caagtccaga agtagaagaa caacgcacac 8161 tacgcgtcct agagatgaca tctgactggt tgcaccgagg acctagagag ttctgcatta 8221 aagttctctg cccttacatg cccaaggtta tagaaaaaat ggaagttctg cagcgtcgct 8281 tcggaggtgg gctagtgcgt ctccccctgt cccgaaactc caatcacgag atgtattggg 8341 ttagtggagc cgctggcaat gtggtgcacg ctgtgaacat gaccagccag gtattactgg 8401 ggcgaatgga tcgcacagtg tggagagggc caaagtatga ggaagatgtc aacctaggga 8461 gcggaacaag agccgtggga aagggagaag tccatagcaa tcaggagaaa atcaagaaga 8521 gaatccagaa gcttaaagaa gaattcgcca caacgtggca caaagaccct gagcatccat 8581 accgcacttg gacataccac ggaagctatg aagtgaaggc tactggctca gccagctctc 8641 tcgtcaacgg agtggtgaag ctcatgagca aaccttggga cgccattgcc aacgtcacca 8701 ccatggccat gactgacacc accccttttg gacagcaaag agttttcaag gagaaagttg 8761 acacgaaggc tcctgagcca ccagctggag ccaaggaagt gctcaacgag accaccaact 8821 ggctgtgggc ctacttgtca cgggaaaaaa gaccccgctt gtgcaccaag gaagaattca 8881 ttaagaaagt taacagcaac gcggctcttg gagcagtgtt cgctgaacag aatcaatgga 8941 gcacggcgcg tgaggctgtg gatgacccgc ggttttggga gatggttgat gaagagaggg 9001 aaaaccatct gcgaggagag tgtcacacat gtatctacaa catgatggga aaaagagaga 9061 agaagcctgg agagtttgga aaagctaaag gaagcagggc catttggttc atgtggcttg 9121 gagcacggta tctagagttt gaagctttgg ggttcctgaa tgaagaccat tggctgagcc 9181 gagagaattc aggaggtgga gtggaaggct caggcgtcca aaagctggga tacatcctcc 9241 gtgacatagc aggaaagcaa ggagggaaaa tgtacgctga tgataccgcc gggtgggaca 9301 ctagaattac cagaactgat ttagaaaatg aagctaaggt actggagctc ctagacggtg 9361 aacaccgcat gctcgcccga gccataattg aactgactta caggcacaaa gtggtcaagg 9421 tcatgagacc tgcagcagaa ggaaagaccg tgatggacgt gatatcaaga gaagatcaaa 9481 gggggagtgg acaggtggtc acttatgctc ttaacacttt cacgaacatc gctgtccagc 9541 tcgtcaggct gatggaggct gagggggtca ttggaccaca acacttggaa cagctaccta 9601 ggaaaaacaa gatagctgtc aggacctggc tctttgagaa tggagaggag agagtgacca 9661 ggatggcgat cagcggagac gactgtgccg tcaaaccgct ggacgacaga ttcgccacag 9721 ccctccactt cctcaacgca atgtcaaagg tcagaaaaga catccaggaa tggaagcctt 9781 cgcatggctg gcacgattgg cagcaagttc ccttctgttc taaccatttt caggagattg 9841 tgatgaaaga tggaaggagt atagttgtcc cgtgcagagg acaggatgag ctgataggca 9901 gggctcgcat ctctccagga gctggatgga atgtgaagga cacagcttgc ctggccaaag 9961 catatgcaca gatgtggcta ctcctatact tccatcgcag ggacttgcgt ctcatggcaa 10021 atgcgatttg ctcagcagtg ccagtagatt gggtgcccac aggcaggaca tcctggtcaa 10081 tacactcgaa aggagagtgg atgaccacgg aagacatgct gcaggtctgg aacagagttt 10141 ggattgaaga aaatgaatgg atgatggaca agactccaat cacaagctgg acagacgttc 10201 cgtatgtggg aaagcgcgag gacatctggt gtggcagcct catcggaacg cgatccagag 10261 caacctgggc tgagaacatc tatgcggcga taaaccaggt tagagctgtc attgggaaag 10321 aaaattatgt tgactacatg acctcactca ggagatacga agacgtcttg atccaggaag 10381 acagggtcat ctagtgtgat ttaaggtaga aaagtagact atgtaaacaa tgtaaatgag 10441 aaaatgcatg catatggagt caggccagca aaagctgcca ccggatactg ggtagacggt 10501 gctgcctgcg tctcagtccc aggaggactg ggttaacaaa tctgacaaca gaaagtgaga 10561 aagccctcag aaccgtctcg gaagtaggtc cctgctcact ggaagttgaa agaccaacgt 10621 caggccacaa atttgtgcca ctccgctagg gagtgcggcc tgcgcagccc caggaggact 10681 gggttaccaa agccgttgag cccccacggc ccaagcctcg tctaggatgc aatagacgag 10741 gtgtaaggac tagaggttag aggagacccc gtggaaacaa caatatgcgg cccaagcccc 10801 ctcgaagctg tagaggaggt ggaaggacta gaggttagag gagaccccgc atttgcatca 10861 aacagcatat tgacacctgg gaatagactg ggagatcttc tgctctatct caacatcagc 10921 tactaggcac agagcgccga agtatgtagc tggtggtgag gaagaacaca ggatct //
GenBank-Updates@genbank.bio.net (02/23/91)
LOCUS JEVSAV 10976 bp ss-RNA VRL 23-FEB-1991 DEFINITION Japanese encephalitis virus strain SA(V), complete genome. ACCESSION D90194 KEYWORDS complete genome; pathogenesis; polyprotein; viral attenuation. SOURCE Japanese encephalitis virus (strain SA14), cDNA to viral RNA. ORGANISM Japanese encephalitis virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Flaviviridae; Flavivirus (arbovirus group B). REFERENCE 1 (bases 1 to 10976) AUTHORS Aihara,S., Rao,C., Yu,Y.X., Lee,T., Watanabe,K., Komiya,T., Sumiyoshi,H., Hashimoto,H. and Nomoto,A. TITLE Identification of mutations occurred on the genome of Japanese encephalitis virus during the attenuation process JOURNAL Unpublished (1990) STANDARD full staff_entry COMMENT These data kindly submitted in computer readable form by: Akio Nomoto The Tokyo Metropolitan Institute of Medical Science Honkomagome, Bunkyo-ku Tokyo 113 Japan Phone: 03-823-2101 x5267 Fax: 03-828-8945 FEATURES Location/Qualifiers CDS 96..10394 /note="polyprotein" BASE COUNT 3036 a 2528 c 3117 g 2295 t ORIGIN 1 agaagtttat ctgtgtgaac ttcttggctt agtatcgttg agaagaatcg agagattagt 61 gcagtttaaa cagtttttta gaacggaaga taaccatgac taaaaaacca ggagggcccg 121 gtaaaaaccg ggctatcaat atgctgaaac gcggcctacc ccgcgtattc ccactagtgg 181 gagtgaagag ggtagtaatg agcttgttgg acggcagagg gccagtacgt ttcgtgctgg 241 ctcttatcac gttcttcaag tttacagcat tagccccgac caaggcgctt ttaggccgat 301 ggaaagcagt ggaaaagagt gtggcaatga aacatcttac tagtttcaaa cgagaacttg 361 gaacactcat tgacgccgtg aacaagcggg gcagaaagca aaacaaaaga ggaggaaatg 421 aaggctcaat catgtggctc gcgagcttgg cagttgtcat agcttgtgca ggagccatga 481 agttgtcgaa tttccagggg aagcttttga tgaccatcaa caacacggac attgcagacg 541 ttatcgtgat tcccacctca aaaggagaga acagatgctg ggtccgggca atcgacgtcg 601 gctacatgtg tgaggacact atcacgtacg aatgtcctaa gcttaccatg ggcaatgatc 661 cagaggatgt ggattgctgg tgtgacaacc aagaagtcta cgtccaatat ggacggtgca 721 cgcggaccag gcattccaag cgaagcagga gatccgtgtc ggtccaaaca catggggaga 781 gttcactagt gaataaaaaa gaggcttggc tggattcaac gaaagccaca cgatatctca 841 tgaaaactga gaactggatc ataaggaatc ctggctatgc tttcctggcg gcggtacttg 901 gctggatgct tggcagtaac aacggtcaac gcgtggtatt taccatcctc ctgctgttgg 961 tcgctccggc ttacagtttt aattgtctgg gaatgggcaa tcgtgacttc atagaaggag 1021 ccagtggagc cacttgggtg gacttggtgc tagaaggaga tagctgcttg acaatcatgg 1081 caaacgacaa accaacattg gacgtccgca tgattaacat cgaagctagc caacttgctg 1141 aggtcagaag ttactgctat catgcttcag tcactgacat ctcgacggtg gctcggtgcc 1201 ccacgactgg agaagctcac aacgagaagc gagctgatag tagctatgtg tgcaaacaag 1261 gcttcactga ccgtgggtgg ggcaacggat gtggactttt cgggaaggga agcattgaca 1321 catgtgcaaa attctcctgc accagtaaag cgattgggag aacaatccag ccagaaaaca 1381 tcaaatacga agttggcatt tttgtgcatg gaaccaccac ttcggaaaac catgggaatt 1441 attcagcgca agttggggcg tcccaggcgg caaagtttac agtaacaccc aatgctcctt 1501 cgataaccct caaacttggt gactacggag aagtcacact ggactgtgag ccaaggagtg 1561 gactgaacac tgaagcgttt tacgtcatga ccgtggggtc aaagtcattt ctggtccata 1621 gggagtggtt tcatgacctc gctctcccct ggacgtcccc ttcgagcaca gcgtggagaa 1681 acagagaact cctcatggaa tttgaagggg cgcacgccac aaaacagtcc gttgttgctc 1741 ttgggtcaca ggaaggaggc ctccatcagg cgttggcagg agccatcgtg gtggagtact 1801 caagctcagt gaagttaaca tcaggccacc tgaaatgtag gctgaaaatg gacaaactgg 1861 ctctgaaagg cacaacctat ggcatgtgta cagaaaaatt ctcgttcgcg aaaaatccgg 1921 cggacactgg tcacggaaca gttgtcattg aactctccta ctctgggagt gatggctcct 1981 gcaaaattcc gattgtttcc gttgcgagcc tcaatgacat gacccccgtt gggcggctgg 2041 tgacagtgaa ccccttcgtc gcgacttcca gtgccaactc aaaggtgctg gtcgagatgg 2101 aacccccctt cggagactcc tacatcgtag ttggaagggg agacaagcag atcaaccacc 2161 attggcacaa agctggaagc acgctgggca aggccttttc aacaactttg aagggagctc 2221 aaagactggc agcgttgggc gacacagcct gggactttgg ctctattgga ggggtcttca 2281 actccatagg aaaagccgtt caccaagtgt ttggtggtgc cttcagaaca ctctttgggg 2341 gaatgtcttg gatcacacaa gggctaatgg gtgccctact gctctggatg ggcgtcaacg 2401 cacgagaccg atcaattgct ttggccttct tagccacagg gggtgtgctc gtgttcttag 2461 cgaccaatgt gcatgctgac actggatgtg ccattgacat cacaagaaaa gagatgagat 2521 gtggaagtgg catcttcgtg cacaacgacg tggaagcctg ggtggatagg tataaatatt 2581 tgccagaaac gcccagatcc ctagcgaaga tcgtccacaa agcgcacaag gaaggcgtgt 2641 gcggagtcag atctgtcact agactggagc accaaatgtg ggaagccgta cgggacgaat 2701 tgaacgtcct gctcaaagag aatgcagtgg acctcagtgt ggttgtgaac aagcccgtgg 2761 gaagatatcg ctcagcccct aaacgcctat ccatgacgca agagaagttt gaaatgggct 2821 ggaaagcatg gggaaaaagc attctctttg ccccggaatt ggctaactcc acatttgtcg 2881 tagatggacc tgagacaaag gaatgccctg atgagcacag agcttggaac agcatgcaaa 2941 tcgaagactt cggctttggc atcacatcaa cccgtgtgtg gctgaaaatt agagaggaga 3001 gcactgacga gtgtgatgga gcgatcatag gcacggctgt caaaggacat gtggcagtcc 3061 atagtgactt gtcgtactgg attgagagtc gctacaacga cacatggaaa cttgagaggg 3121 cagtctttgg agaggtcaaa tcttgcactt ggccagagac acacaccctt tggggagatg 3181 atgttgagga aagtgaactc atcattccgc acaccatagc cggaccaaaa agcaagcaca 3241 atcggaggga agggtataag acacaaaacc agggaccttg ggatgagaat ggcatagtct 3301 tggactttga ttattgccca gggacaaaag tcaccattac agaggattgt ggcaagagag 3361 gcccttcggt cagaaccact actgacagtg gaaagttgat cactgactgg tgctgtcgca 3421 gttgctccct tccgccccta cgattccgga cagaaaatgg ctgctggtac ggaatggaaa 3481 tcagacctgt taggcatgat gaaacaacac tcgtccgatc acaggttgat gctttcaatg 3541 gtgaaatggt tgaccctttt cagctgggcc ttctggtgat gtttctggcc acccaggagg 3601 tccttcgcaa gaggtggacg gccagattga ccattcctgc ggttttgggg gccctacttg 3661 tgctgatgct tgggggcatc acttacactg atttggcgag gtatgtggtg ctagtcgctg 3721 ctgctttcgc agaggccaac agtggaggag acgtcctgca ccttgctttg attgccgttt 3781 ttaagatcca accagcattt ctagtgatga acatgcttag cacgagatgg acgaaccaag 3841 aaaacgtggt tctggtccta ggggctgcct ttttccaatt ggcctcagta gatctgcaaa 3901 taggagtcca cggaatcctg aatgccgccg ctatagcatg gatgattgtc cgagcgatca 3961 ccttccccac aacctcctcc gtcaccatgc cagtcttagc gcttctaact ccggggatga 4021 gggctctata cctagacact tacagaatca tcctcctcgt catagggatt tgctccctgc 4081 tgcacgagag gaaaaagacc atggcaaaaa agaaaggagc tgtactcttg ggcttagcgc 4141 tcacatccac tggatggttc tcgcccacca ctatagctgc cggactaatg gtctgcaacc 4201 caaacaagaa gagagggtgg ccagctactg agtttttgtc ggcagttgga ttgatgtttg 4261 ccatcgtagg tggtttggcc gagttggata ttgaatccat gtcaataccc ttcatgctgg 4321 caggtctcat ggcagtgtcc tacgtggtgt caggaaaagc aacagatatg tggcttgaac 4381 gggccgccga catcagctgg gagatggatg ctgcaatcac aggaagcagt cggaggctgg 4441 atgtgaaact ggatgatgac ggagattttc acttgattga tgatcccggt gttccatgga 4501 aggtctgggt cctgcgcatg tcttgcattg gcttagccgc cctcacgcct tgggccatcg 4561 ttcccgccgc tttcggttat tggctcactt taaaaacaac aaaaagaggg ggcgtgtttt 4621 gggacacgcc atccccaaaa ccttgctcaa aaggagacac cactacagga gtctaccgaa 4681 ttatggctag agggattctt ggcacttacc aggccggcgt cggagtcatg tacgagaatg 4741 ttttccacac actatggcac acaactagag gagcagccat tatgagtgga gaaggaaaat 4801 tgacgccata ctggggtagt gtgagagaag accgcatagc ttacggaggc ccatggaggt 4861 ttgaccgaaa atggaatgga acagatgacg tgcaagtgat cgtggtagaa ccggggaagg 4921 ctgcagtaaa catccagaca aaaccaggag tgtttcggac tcccttcggg gaggttgggg 4981 ctgttagtct ggattacccg cgaggaacat ccggctcacc cattctggat tccaatggag 5041 acattatagg cctatacggc aatggagttg agcttggcga tggctcatac gtcagcgcca 5101 tcgtgcaggg tgaccgtcag gaggaaccag tcccagaagc ttacacccca aacatgttga 5161 gaaagagaca gatgactgtg ctagatttgc accctggttc agggaaaacc aggaaaattc 5221 tgccacaaat aatcaaggac gctatccagc agcgcctaag aacagctgtg ttggcaccga 5281 cgcgggtggt agcagcagaa atggcagaag ttttgagagg gctcccagta cgatatcaaa 5341 cttcagcagt gcagagagag caccaaggga atgaaatagt ggatgtgatg tgccacgcca 5401 ctctgaccca tagactgatg tcaccgaaca gagtgcccaa ctacaaccta tttgtcatgg 5461 atgaagctca tttcaccgac ccagccagta tagccgcacg aggatacatt gctaccaagg 5521 tggaattagg ggaggcagca gccatcttta tgacagcgac cccgcctgga accacggatc 5581 cttttcctga ctcaaatgcc ccaatccatg atttgcaaga tgagatacca gacagggcat 5641 ggagcagtgg atacgaatgg atcacagaat atgcgggtaa aaccgtgtgg tttgtggcga 5701 gcgtaaaaat ggggaatgag attgcaatgt gcctccaaag agcggggaaa aaggtcatcc 5761 aactcaaccg caagtcctat gacacagaat acccaaaatg taagaatgga gactgggatt 5821 ttgtcattac caccgacatc tctgaaatgg gggccaactt cggtgcgagc agggtcatcg 5881 actgtagaaa gagcgtgaaa cccaccatct tagaagaggg agaaggcaga gtcatcctcg 5941 gaaacccatc tcccataacc agtgcaagcg cagctcaacg gaggggcaga gtaggcagaa 6001 accccaacca agttggagat gaataccact atgggggggc taccagtgaa gatgacagta 6061 acctagccca ttggacagag gcaaagatca tgttagacaa catacacatg cccaatggac 6121 tggtggccca gctctatgga ccagagaggg aaaaggcttt cacaatggat ggcgaatacc 6181 gtctcagagg tgaagaaaag aaaaacttct tagagctgct taggacggct gacctcccgg 6241 tgtggctggc ctacaaggtg gcgtccaatg gcattcagta caccgacaga aagtggtgtt 6301 ttgatgggcc gcgtacgaat gccatactgg aggacaacac cgaggtagag atagtcaccc 6361 ggatgggtga gaggaaaatc ctcaagccga gatggcttga tgcaagagtt tatgcagatc 6421 accaagccct caagtggttc aaagactttg cagcagggaa gagatcagcc gttagcttca 6481 tagaggtgct cggtcgcatg cctgagcatt tcatgggaaa gacgcgggaa gctttagaca 6541 ccatgtactt ggttgcaacg gctgagaaag gtgggaaagc acaccgaatg gctctcgaag 6601 agctgccaga tgcactggaa accatcacac ttattgtcgc cattactgtg atgacaggag 6661 gattcttcct actaatgatg cagcgaaagg gtatagggaa gatgggtctt ggagctctag 6721 tgctcacgct agctaccttc ttcctgtggg cggcagaggt tcctggaacc aaaatagcag 6781 ggaccctgct gatcgccctg ctgctgatgg tggttctcat cccagaaccg gaaaaacaga 6841 ggtcacagac agataaccaa ctggcggtgt ttctcatctg tgtcttgacc gtggttggag 6901 tggtggcagc aaacgagtac gggatgctag aaaaaaccaa agcagatctc aagagcatgt 6961 ttggcggaaa gacgcaggca tcaggactga ctggattgcc aagcatggca ctggacctgc 7021 gtccagccac agcctgggca ctgtatgggg ggagcacagt cgtgctaacc cctcttctga 7081 agcacctgat cacgtcggaa tacgtcacca catcgctagc ctcaattaac tcacaagctg 7141 gctcattatt cgtcttgcca cgaggcgtgc cttttaccga cctagacttg accgttggcc 7201 tcgtcttcct tggctgttgg ggtcaaatca ccctcacaac gtttctgaca gccatggttc 7261 tggcgacact tcactatggg tacatgctcc ctggatggca agcagaagca ctcagggctg 7321 cccagagaag gacagcggct ggaataatga agaatgccgt tgttgacgga atggtcgcca 7381 ctgatgtgcc tgaactggaa aggactactc ctctgatgca aaagaaagtc ggacaggtgc 7441 tcctcatagg ggtaagcgtg gcagcgttcc tcgtcaaccc taatgtcacc actgtgagag 7501 aagcaggggt gttggtgacg gcggctacgc ttactttgtg ggacaatgga gccagtgccg 7561 tttggaattc caccacagcc acgggactct gccatgtcat gcgaggtagc tacctggctg 7621 gaggctccat tgcttggact ctcatcaaga acgctgataa gccctccttg aaaaggggaa 7681 ggcctggggg caggacgcta ggggagcagt ggaaggaaaa actaaatgcc atgagcagag 7741 aagagttttt taaataccgg agagaggcca taatcgaggt ggaccgcact gaagcacgca 7801 gggccagacg tgaaaataac atagtgggag gacatccggt ttcgcgaggc tcagcaaaac 7861 tccgttggct cgtggagaaa ggatttgtct cgccaatagg aaaagtcatt gatctagggt 7921 gtgggcgtgg aggatggagc tactacgcag caaccctgaa gaaggtccag gaagtcagag 7981 gatacacgaa aggtggggcg ggacatgaag aaccgatgct catgcagagc tacggctgga 8041 acctggtctc cctgaagagt ggagtggacg tgttttacaa accttcagag cccagtgaca 8101 ccctgttctg tgacataggg gaatcctccc caagtccaga agtagaagaa caacgcacac 8161 tacgcgtcct agagatgaca tctgactggt tgcaccgagg acctagagag ttctgcatta 8221 aagttctctg cccttacatg cccaaggtta tagaaaaaat ggaagttctg cagcgccgct 8281 tcggaggtgg gctagtgcgt ctccccctgt cccgaaactc caatcacgag atgtattggg 8341 ttagtggagc cgctggcaat gtggtgcacg ctgtgaacat gaccagccag gtactactgg 8401 ggcgaatgga tcgcacagtg tggagagggc caaagtatga ggaagatgtc aacctaggga 8461 gcggaacaag agccgtggga aagggagaag tccatagcaa tcaggagaaa atcaagaaga 8521 gaatccagaa gcttaaagaa gaattcgcca caacgtggca caaagaccct gagcatccat 8581 accgcacttg gacataccac ggaagctatg aagtgaaggc tactggctca gccagctctc 8641 tcgtcaacgg agtggtgaag ctcatgagca aaccttggga cgccattgcc aacgtcacca 8701 ccatggccat gactgacacc accccttttg gacagcaaag agttttcaag gagaaagttg 8761 acacgaaggc tcctgagcca ccagctggag ccaaggaagt gctcaacgag accaccaact 8821 ggctgtgggc ccacttgtca cgggaaaaaa gaccccgctt gtgcaccaag gaagaattca 8881 taaagaaagt caacagcaac gcggctcttg gagcagtgtt cgctgaacag aatcaatgga 8941 gcacggcgcg tgaggctgtg gatgacccgc ggttttggga gatggttgat gaagagaggg 9001 aaaaccatct gcgaggagag tgtcacacat gtatctacaa catgatggga aaaagagaga 9061 agaagcctgg agagtttgga aaagctaaag gaagcagggc catttggttc atgtggcttg 9121 gagcacggta tctagagttt gaagctttgg ggttcctgaa tgaagaccat tggctgagcc 9181 gagagaattc aggaggtgga gtggaaggct caggcgtcca aaagctggga tacatcctcc 9241 gtgacatagc aggaaagcaa ggagggaaaa tgtacgctga tgataccgcc gggtgggaca 9301 ctagaattac cagaactgat ttagaaaatg aagctaaggt actggagctc ctagacggtg 9361 aacaccgcat gctcgcccga gccataattg aactgactta caggcacaaa gtggtcaagg 9421 tcatgagacc tgcagcagaa ggaaagaccg tgatggacgt gatatcaaga gaagatcaaa 9481 gggggagtgg acaggtggtc acttatgctc ttaacacttt cacgaacatc gctgtccagc 9541 tcgtcaggct gatggaggct gagggggtca ttggaccaca acacttggaa cagctaccta 9601 ggaaaaacaa gatagctgtc aggacctggc tctttgagaa tggagaggag agagtgacca 9661 ggatggcgat cagcggagac gactgtgtcg tcaagccgct ggacgacaga ttcgccacag 9721 ccctccactt cctcaacgca atgtcaaagg tcagaaaaga catccaggaa tggaagcctt 9781 cgcatggctg gcacgattgg cagcaagttc ccttctgctc taaccatttt caggagattg 9841 tgatgaaaga tggaaggagt atagttgtcc cgtgcagagg acaggatgag ctgatagaca 9901 gggctcgcat ctctccagga gctggatgga atgtgaagga cacagcttgc ctggccaaag 9961 catatgcaca gatgtggcta ctcctatact tccatcgcag ggacttgcgt ctcatggcaa 10021 atgcgatttg ctcagcagtg ccagtggatt gggtgcccac aggcaggaca tcctggtcaa 10081 tacactcgaa aggagagtgg atgaccacgg aagacatgct gcaggtctgg aacagagtct 10141 ggattgaaga aaatgaatgg atgatggaca agactccaat cacaagctgg acagacgttc 10201 cgtatgtggg aaagcgtgag gacatctggt gtggcagcct catcggaacg cgatccagag 10261 caacctgggc tgagaacatc tatgcggcga taaaccaggt tagagctgtc attgggaaag 10321 aaaattatgt tgactacatg acctcactca ggagatacga agacgtcttg atccaggaag 10381 acagggtcat ctagtgtgat ttaaggtaga aaagtagact atgtaaataa tgtaaatgag 10441 aaaatgcatg catatggagt caggccagca aaagctgcca ccggatactg ggtagacggt 10501 gctgcctgcg tctcagtccc aggaggactg ggttaacaaa tctgacaaca gaaagtgaga 10561 aagccctcag aaccgtctcg gaagtaggtc cctgctcact ggaagttgaa agaccaacgt 10621 caggccacaa atttgtgcca ctccgctagg gagtgcggcc tgcgcagccc caggaggact 10681 gggttaccaa agccgttgag cccccacggc ccaagcctcg tctaggatgc aatagacgag 10741 gtgtaaggac tagaggttag aggagacccc gtggaaacaa caacatgcgg cccaagcccc 10801 ctcgaagctg tagaggaggt ggaaggacta gaggttagag gagaccccgc atttgcatca 10861 aacagcatat tgacacctgg gaatagactg ggagatcttc tgctctatct caacatcagc 10921 tactaggcac agagcgccga agtatgtagc tggtggtgag gaagaacaca ggatct //