GenBank-Updates@genbank.bio.net (02/06/91)
LOCUS HUMEGFAA 990 bp ss-mRNA PRI 06-FEB-1991
DEFINITION Human heparin-binding vascular endothelial growth factor (VEGF)
mRNA, complete cds.
ACCESSION M32977
KEYWORDS angiogenic mitogen; vascular endothelial growth factor.
SOURCE Human promyelocytic leukemia cell line HL60, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 990)
AUTHORS Leung,D.W., Cachianes,G., Kuang,W.-., Goeddel,D.V. and Ferrara,N.
TITLE Vascular endothelial growth factor is a secreted angiogenic mitogen
JOURNAL Science 246, 1306-1309 (1989)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA <1..1536
/note="VEGF mRNA"
CDS 57..632
/gene="VEGF"
/codon_start=57
/product="vascular endothelial growth factor"
sig_peptide 57..134
/gene="VEGF"
/codon_start=57
mat_peptide 135..629
/gene="VEGF"
/codon_start=135
/product="vascular endothelial growth factor"
BASE COUNT 255 a 269 c 276 g 190 t
ORIGIN
1 cagtgtgctg gcggcccggc gcgagccggc ccggccccgg tcgggcctcc gaaaccatga
61 actttctgct gtcttgggtg cattggagcc tcgccttgct gctctacctc caccatgcca
121 agtggtccca ggctgcaccc atggcagaag gaggagggca gaatcatcac gaagtggtga
181 agttcatgga tgtctatcag cgcagctact gccatccaat cgagaccctg gtggacatct
241 tccaggagta ccctgatgag atcgagtaca tcttcaagcc atcctgtgtg cccctgatgc
301 gatgcggggg ctgctgcaat gacgagggcc tggagtgtgt gcccactgag gagtccaaca
361 tcaccatgca gattatgcgg atcaaacctc accaaggcca gcacatagga gagatgagct
421 tcctacagca caacaaatgt gaatgcagac caaagaaaga tagagcaaga caagaaaatc
481 cctgtgggcc ttgctcagag cggagaaagc atttgtttgt acaagatccg cagacgtgta
541 aatgttcctg caaaaacaca gactcgcgtt gcaaggcgag gcagcttgag ttaaacgaac
601 gtacttgcag atgtgacaag ccgaggcggt gagccgggca ggaggaagga gcctccctca
661 gggtttcggg aaccagatct ctcaccagga aagactgata cagaacgatc gatacagaaa
721 ccacgctgcc gccaccacac catcaccatc gacagaacag tccttaatcc agaaacctga
781 aatgaaggaa gaggagactc tgcgcagagc actttgggtc cggagggcga gactccggcg
841 gaagcattcc cgggcgggtg acccagcacg gtccctcttg gaattggatt cgccatttta
901 tttttcttgc tgctaaatca ccgagcccgg aagattagag agttttattt ctgggattcc
961 tgtagacaca ccgcggccgc cagcacactg
//GenBank-Updates@genbank.bio.net (03/01/91)
LOCUS HUMEGFAA 990 bp ss-mRNA PRI 01-MAR-1991
DEFINITION Human heparin-binding vascular endothelial growth factor (VEGF)
mRNA, complete cds.
ACCESSION M32977
KEYWORDS angiogenic mitogen; vascular endothelial growth factor.
SOURCE Human promyelocytic leukemia cell line HL60, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 990)
AUTHORS Leung,D.W., Cachianes,G., Kuang,W.-J., Goeddel,D.V. and Ferrara,N.
TITLE Vascular endothelial growth factor is a secreted angiogenic mitogen
JOURNAL Science 246, 1306-1309 (1989)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA <1..990
/note="VEGF mRNA"
CDS 57..632
/product="vascular endothelial growth factor"
/gene="VEGF"
/codon_start=57
sig_peptide 57..134
/gene="VEGF"
/codon_start=57
mat_peptide 135..629
/product="vascular endothelial growth factor"
/gene="VEGF"
/codon_start=135
BASE COUNT 255 a 269 c 276 g 190 t
ORIGIN
1 cagtgtgctg gcggcccggc gcgagccggc ccggccccgg tcgggcctcc gaaaccatga
61 actttctgct gtcttgggtg cattggagcc tcgccttgct gctctacctc caccatgcca
121 agtggtccca ggctgcaccc atggcagaag gaggagggca gaatcatcac gaagtggtga
181 agttcatgga tgtctatcag cgcagctact gccatccaat cgagaccctg gtggacatct
241 tccaggagta ccctgatgag atcgagtaca tcttcaagcc atcctgtgtg cccctgatgc
301 gatgcggggg ctgctgcaat gacgagggcc tggagtgtgt gcccactgag gagtccaaca
361 tcaccatgca gattatgcgg atcaaacctc accaaggcca gcacatagga gagatgagct
421 tcctacagca caacaaatgt gaatgcagac caaagaaaga tagagcaaga caagaaaatc
481 cctgtgggcc ttgctcagag cggagaaagc atttgtttgt acaagatccg cagacgtgta
541 aatgttcctg caaaaacaca gactcgcgtt gcaaggcgag gcagcttgag ttaaacgaac
601 gtacttgcag atgtgacaag ccgaggcggt gagccgggca ggaggaagga gcctccctca
661 gggtttcggg aaccagatct ctcaccagga aagactgata cagaacgatc gatacagaaa
721 ccacgctgcc gccaccacac catcaccatc gacagaacag tccttaatcc agaaacctga
781 aatgaaggaa gaggagactc tgcgcagagc actttgggtc cggagggcga gactccggcg
841 gaagcattcc cgggcgggtg acccagcacg gtccctcttg gaattggatt cgccatttta
901 tttttcttgc tgctaaatca ccgagcccgg aagattagag agttttattt ctgggattcc
961 tgtagacaca ccgcggccgc cagcacactg
//