GenBank-Updates@genbank.bio.net (03/01/91)
LOCUS TRBLEUMBD 3146 bp ds-DNA INV 01-MAR-1991
DEFINITION Trypanosoma brucei leucine repeat region.
ACCESSION M58701 M38528
KEYWORDS .
SOURCE T.brucei (strain EATRO) bloodstage DNA, from Bos taurus and Rattus
norvegicus.
ORGANISM Trypanosoma brucei
Eukaryota; Animalia; Protozoa; Sarcomastigophora; Mastigophora;
Kinetoplastida; Trypanosomatina; Trypanosomatidae.
REFERENCE 1 (bases 1 to 3146)
AUTHORS Smiley,B., Stadnyk,A.W., Myler,P. and Stuart,K.
TITLE Trypanosome leucine repeat (T-LR) gene in the VSG expression site
encodes a putative metal-binding domain and a region resembling
protein binding domains of yeast, Drosophila, and mammalian
proteins
JOURNAL Mol. Cell. Biol. 10, 6436-6444 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 546..2438
/function="unknown"
/product="leucine repeat protein"
/gene="T-LR"
/codon_start=546
protein_bind 573..680
/function="putative metal-binding site"
/gene="T-LR"
protein_bind 684..776
/function="putative nucleic binding recognition domain"
/gene="T-LR"
repeat_region 1554..1622
/rpt_family="leucine-rich"
/gene="T-LR"
BASE COUNT 802 a 464 c 826 g 1054 t
ORIGIN
1 aagcttaaat taacgttttt ttttttgtgt gtgtgtgaag aaggtgaacc ccgtgaagtg
61 gaggctatag cgaagtaaaa gtgtctttct gggcttattc ctccagtcta ccccaatctt
121 tcttcattcg gggattttgg cttgtaagat gtacttccca aatgaaactg ctgacgacta
181 aaccctattt tctatatcta atacttgcgt ataacttcct acatgtttcc atatgcttat
241 tgtaactttc cctcatattc tctctcaccc attctctcta ttttaccttt agacaaccaa
301 ggaatatgaa actgagcaat gtctgccatg atgttgtcag tttgaatgtt aactgtgact
361 gctagtgtgc tgtgtttttg ttactggcaa tccagtttat gatactgtaa tgttctatct
421 acatatttac tcttatgcat agtgatgttt tgtccttttt gtgcgatgtg tgcttcgttt
481 ttttttcacg attgagtgaa tgtttttagg atcgcaacga agcctgtaat ttcaaaggta
541 ctgaaatgac tggccgtagc acatatggga tgtgcgcggt atgcagagag ccctgggcag
601 aaggggcagt ggagcttttg ccgtgtagac atgtattctg caccgcatgc gtcgtgcaac
661 gttggaggtg tccctcttgt caacggcgta tcggagggag acggaaggct aaccctcacc
721 ttttgcgtga gatagctgat gtgacgatgg aattgaaaag atataggaag ggtcgtagtg
781 gtattgacgt gactcagatg gcgagaaaac taggtggtgg tggtgtaacc acaagctctg
841 agatctttcg acgtcttgag gggtcaaaaa atggtaggtg gaaaatactg aatttgtctg
901 gatgcgggag tgaactgcag gatttgacgg cactacgtga tctggaagct cttgaggact
961 tggacttaag tgaatgtgcg aatctcgagt tgagggaatt gatggtggtt cttaccctcc
1021 ggaacttgag gaagttgcgc atgaaaagaa caatggtgaa tgatatgtgg tgcagctcta
1081 ttggtttgtt gaagtttctc gtgcacttgg aagttgatgg aagccgcggt gttacggaca
1141 tcacgggtct ttttaggctg aaaacccttg aggctttgtc tctggataac tgtataaata
1201 ttacgaaagg gtttgataag atatgtgctt tgcctcaatt gacgagtttg tcgctttgcc
1261 aaacaaatgt tacagacaag gaccttcgat gtattcatcc tgatgggaag ctgaagatgc
1321 tagatatcag cagttgccat gaaattacag acttaactgc tattgggggt gtgaggtcac
1381 ttgaaaagtt gtctttgagt ggctgctgga atgttacaaa gggattggag gagctttgta
1441 aattttccaa tcttagggag ttggatatct ccggttgtct ggtgctaggg agtgcggttg
1501 tgttaaagaa tttgattaac ttgaaagtat tatctgtctc taactgcaaa aactttaaag
1561 atttgaatgg actagaaaga ttggtgaact tggagaagct aaatctatcg ggatgccatg
1621 gtgtctcttc tctgggcttc gtagcgaatt tatctaactt gaaggagttg gatatcagtg
1681 gttgtgagtc gctggtgtgc ttcgacgggt tacaagactt gaataatttg gaggtattgt
1741 atcttcgtga tgttaagtcg tttacgaatg ttggtgcgat aaaaaatttg agtaaaatgc
1801 gggagttaga tctttccggt tgtgagagaa taacaagcct gagtggattg gaaactttga
1861 aggggttgga agagttgagt ctggaaggtt gtggggaaat tatgagtttt gatcccatat
1921 ggagtctcta ccacttgagg gtgctctatg tgagtgaatg tggaaattta gaagatttga
1981 gtggacttca gtgtttgact ggtttggagg aaatgtatct tcacgggtgt aggaaatgta
2041 cgaattttgg tcccatatgg aatttgagaa atgtttgtgt gctggaactg agttgctgcg
2101 agaatttaga tgatttgagt ggacttcagt gtctgactgg tttggaggaa ctgtatctta
2161 ttgggtgtga ggaaattaca actattggtg tagtcgggaa tttgcgtaat ttgaagtgtt
2221 tgagtacgtg ttggtgtgca aacttaaagg aattgggtgg attagagagg ttggtgaatt
2281 tggagaaatt ggatctctcg ggatgttgcg gactttcgag ttctgttttc atggaattga
2341 tgtctcttcc aaagttacag tggttttatg gtttcggctc acgcgttcct gatattgttc
2401 ttaaagaatt gaagagacga ggtgtgcata tattttgatg ataatttatt ttacttttaa
2461 ctttcgttta ttttagtttt acacagatag tttccgtttc cttcaattct atatattagc
2521 agctttattt atacataaat tattttcttt tatgtggatg tgtgtgtatt acgaaaaagt
2581 attttacaaa gacgtttttg tgcagtatct ttctgcctac tgctattttt gttatctagt
2641 cggttcgttt ctttcatagg ttttgcctta agttaaacca tatgttatct ggcgtgggca
2701 ggcacgagcg ggacacctta tatttgctga ggtatcgctt gcatttttag catgccctga
2761 ggtttgcggt atatgagcca gaaccgaagc gcgttgcgag gtggagaaag gcgacttttt
2821 gacgctttgg atctgtgaca accgagatgg caatgtgtaa atgtgcagat atttggatga
2881 tggtagtaga aataataata atagttattg aagggaatca tgtacgtgtg cacccattaa
2941 tgtaataata ttataacaat agcagtagaa gtggattgca gagtgatgct tgtgagagag
3001 cattgacgat agcgaatgat tgtggtagtt tccacgcgaa tgttgtataa ttattggtat
3061 attcgaatta ataagtgcag ctagatgccg tgatttacat tacagtgcgt aggtacgatt
3121 tatcaacgca ggaaacagct gaattc
//