GenBank-Updates@genbank.bio.net (03/01/91)
LOCUS VIBTOXS 630 bp ds-DNA BCT 01-MAR-1991
DEFINITION Vibrio cholerae transmembrane regulatory protein (toxS) and
transmembrane DNA-binding protein (tox-R) genes, complete cds, and
3' end.
ACCESSION M62761 M37768
KEYWORDS ToxR protein; ToxS protein; transmembrane DNA-binding protein;
transmembrane regulatory protein.
SOURCE Vibrio choleae (strain E7946) DNA, clone pVM35.
ORGANISM Vibrio cholerae
Prokaryota; Bacteria; Gracilicutes; Scotobacteria; Facultatively
anaerobic rods; Vibrionaceae.
REFERENCE 1 (bases 1 to 630)
AUTHORS DiRita,V.J. and Mekalanos,J.J.
TITLE Periplasmic interaction between two membrane regulatory proteins,
ToxR and ToxS, results in signal transduction and transcriptional
activation
JOURNAL Cell 64, 29-37 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 1..99
/product="transmembrane DNA-binding protein"
/gene="toxR"
/codon_start=1
/partial
CDS 109..630
/function="Interacts with ToxR and stimulates its
activity."
/product="transmembrane regulatory protein"
/gene="toxS"
/codon_start=109
BASE COUNT 182 a 138 c 132 g 178 t
ORIGIN
1 ttaacgctga attacattca cagccctgaa gtttcagggg aaaacataac cttacgcatc
61 gttgctaacc ctaacgatgc catcaaagtg tgtgagtagg atcttgctat gcaaaataga
121 cacatcgcca tgggtattct tctgctctct ctgctgctca gtagctggtt atattggggg
181 agtgacttca agcttgagca agtgttaacc tctcgagaat ggcagtccaa aatggtctct
241 ctgattaaga ccaacagcaa ccgcccggct atggggccac tcagtcgggt agacgtcact
301 tccaatgtga aatatctgcc taatggcact tatttacggg tttcaatcgt aaagctattt
361 tccgatgaca atagtgcaga aagcgtcatt aatatctccg aatttggtga atgggatatc
421 agcgataatt accttttggt tacgccagtc gagtttaaag atatttcgtc aaaccaaagc
481 aaagacttta ctgacgagca attgcagctg attactcaac tgttcaagat ggatgcacaa
541 caaagtcgtc gagtcgacat tgttaacgaa agaaccattc tctttaccag cttaagtcat
601 ggttctaccg tactgttcag taaatcttaa
//