GenBank-Updates@genbank.bio.net (03/02/91)
LOCUS RATSDHG 9578 bp ds-DNA ROD 02-MAR-1991
DEFINITION Rat serine dehydratase gene, (EC 4.2.1.13).
ACCESSION X13119 M38617
KEYWORDS dehydratase; serine dehydratase.
SOURCE Rat (starin Sprague-Dawley and Wistar Furth) DNA.
ORGANISM Rattus rattus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 9578)
AUTHORS Ogawa,H., Su,Y., Dunn,T., Miller,D.A., Matsuda,Y., Fujioka,M. and
Pitot,H.C.
TITLE Nucleotide sequence of the rat searine dehydratase gene
JOURNAL Nucleic Acids Res. 16, 10921-10921 (1988)
STANDARD simple automatic
REFERENCE 2 (sites)
AUTHORS Ogawa,H., Fujioka,M., Date,T., Mueckler,M., Su,Y. and Pitot,C.H.
TITLE Rat serine dehydratase gene codes for two species of mRNA of which
only one is translated into serine dehydratase
JOURNAL J. Biol. Chem. 265, 14407-14413 (1990)
STANDARD full staff_review
COMMENT
[J. Biol. Chem. 265, 14407-14413 (1990)] revises [Nucleic Acids
Res. 16, 10921-10921 (1988)].
Submitted (04-OCT-1988) on tape to the EMBL data library by
H.Ogawa.
FEATURES Location/Qualifiers
prim_transcript <1..>9578
/note="serine dehydratase mRNA and introns"
CDS join(4487..4639,5651..5690,5804..6051,6161..6252,
6756..6983,8546..8670,9100..9305)
/note="serine dehydratase"
/codon_start=4487
intron 2483..3479
/note="serine dehydratase intron A"
intron 2484..3480
/note="serine dehydratase intron A"
intron 3554..4484
/note="serine dehydratase intron B"
intron 3555..4485
/note="serine dehydratase intron B"
exon 4487..4639
/note="serine dehydratase, exon 3 (first expressed exon)"
exon 4488..4640
/note="serine dehydratase, exon 3 (first expressed exon;
EC 4.2.1.13)"
intron 4640..5650
/note="serine dehydratase intron C"
intron 4641..5651
/note="serine dehydratase intron C"
exon 5651..5690
/note="serine dehydratase, exon 4"
exon 5652..5691
/note="serine dehydratase, exon 4"
intron 5691..5803
/note="serine dehydratase intron D"
intron 5692..5804
/note="serine dehydratase intron D"
exon 5804..6051
/note="serine dehydratase, exon 5"
exon 5805..6052
/note="serine dehydratase, exon 5"
intron 6052..6160
/note="serine dehydratase intron E"
intron 6053..6161
/note="serine dehydratase intron E"
exon 6161..6252
/note="serine dehydratase, exon 6"
exon 6162..6253
/note="serine dehydratase, exon 6"
intron 6253..6755
/note="serine dehydratase intron F"
intron 6254..6756
/note="serine dehydratase intron F"
exon 6756..6983
/note="serine dehydratase, exon 7"
exon 6757..6984
/note="serine dehydratase, exon 7"
intron 6984..8545
/note="serine dehydratase intron G"
intron 6985..8546
/note="serine dehydratase intron G"
exon 8546..8670
/note="serine dehydratase, exon 8"
exon 8547..8671
/note="serine dehydratase, exon 8"
intron 8671..9099
/note="serine dehydratase intron H"
intron 8672..9100
/note="serine dehydratase intron H"
exon 9100..9305
/note="serine dehydratase, exon 9"
exon 9101..9306
/note="serine dehydratase, exon 9"
BASE COUNT 2216 a 2492 c 2563 g 2307 t
ORIGIN
1 gaattccgga gctgctgtgg gacagccgcc ctggaattgc gtgtcactga gcaagctgtt
61 cttcaccctg aggacatcca aggaacatct ccagagattg cccagtgtcc cctgggtaca
121 aaaatcacac caccttgagg acagctgagt tgaacagagg tgtgggaagg aggcgtgtga
181 gaatgatcgg caaagctggt gggtgtgggg gctgggaatc cggcgcagat gactgagggc
241 tttcctggca ttctgaggga cctgagtctg atcctcagtg ccatgtgagg tgggcacggt
301 tggcacgcgc ctgtaatggc agcattctga aggcggaggc aggaggatcg ggagttgaag
361 ggcatcttca gctactcggt gagtccgagg ccagcctggg ttatgtgaga ccctgactca
421 attttaaatg ataggtgtgt ccaaactacc cagtcctgtt gtcatctgtc cccagcccaa
481 cccaatcctc cacatcagct ctgcactctc ttaaaactat gagtccctgg gttcaattcc
541 cagtgtcctc agctaccctc tgccctggtg actctcagca aacaccatcc tccaagcctg
601 ccctcatcta caacaaggac taagggagcc cacccactgc tgtgtcttaa cacacgtgaa
661 accccccaca caggaggcaa atgatgtgga accagggtcc cccattgctt tggcaatgag
721 atgctggtcc agagagtaca aggtagctgt gtccacacat gggctttgtg tcatcctggc
781 ttgcctactt ccctctatcc ctgacccaaa cctgtggtca tccctaatgc ggatggtcag
841 aaagaacaat gcacaccaca ggccagaaaa agcagcagac gtggggctgg agagatggct
901 cagtggttaa gagcactggc tgctcctcca gaggtcctga gttcaaatcc cagcaaccac
961 atggtggctc acaaccatct gtcatggact ctgatgccct cttctggtgt gtctgaagtc
1021 agcgatggtg tgctcacata tattaaataa acaaataaat cttttttaaa aaaaagcaca
1081 tggactctgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtttat gctgtggaca
1141 cacaggtctc tgcacacagc ctggaaacgg gtcagagggg atggtcacga tggtcatagt
1201 ggtggtggtg gtgatggtta ctggtactga tactgatggt agtgctgata gtgttgacag
1261 tggtggccaa tagtgaatag tgatggtgat gataaaggtt accaacactg gctacctgtt
1321 caatttcaag tctctcacct aacgcagtcc cacctcttca aagcctggaa cagcggtacc
1381 catgtcatcc ctgtttacac acgaacagag gctctcgagg tcaaggttct tgcccagagc
1441 catgtatcta gtaacagcag agcaggactt gaacccagat cccctttgtc taacccatac
1501 gcccttttat atgaagagga tggcagggga tggtggtaag caaggggtgt caatcatagc
1561 ttgggcgtca acccccaagt cccgcctttc actatctata cgagctgtgc ctcatttcca
1621 ctctgtacag acctgttgga tggttttaca ttgatttggg ttcatgaagc tgagccccat
1681 actccccgcc ctttttcttt ctattttgag acaggctctc actccttagt ccaggctgtc
1741 cttctgcctc agcttctatt gttctggctt gaaggtgtga gttgccatat ggctggcctg
1801 tgtgtttctt ggccataaac agaccagcaa ctgtccggct tttctgttat ttctgggatt
1861 gacccctggg actctggcag gagctcctca gtgctgcgct gcccgcccac gagtcctata
1921 ggcctttcgg agatgaatgt cttcatttgc aacggaaaaa aaaaaaaaaa aaaaaaagaa
1981 cggggagaga aggtgaggcg gaccttggag ggcagaacaa gtggtgcagc atggaccagg
2041 gggcggggat ttctgggggc gtggcctgcc tgggccctca ttggctgccc ggaggctcag
2101 cccggagaat aaagccctgg ggtgtcctgc caactttcca ctctcccagg acacagacaa
2161 aatctaccct tctcgctcgc tctgtccagc tcctcctgtg ccgggtatgt ggccctcagc
2221 ctcagtctca ccccaagatt gacagccaga gcagggtacc gggaagggaa gagggactgg
2281 gactcatcca gttcaagtct ccatgtactg atctgtaaaa tgggacgatg atataggccc
2341 tctagatcag gacgtcgccg gggtggctgt gacttggcca agtgctcgca tgagtcaaat
2401 gacaaggaag agacttctgc cgtggaaccc atgccgcacc ggccaccttt gccaagaccg
2461 cctgtgcctt tttctctcgc aggtcatatc acctatagag gcggatgcga ctggcctctg
2521 gggtgggaat cagtatggag tacactgccc attttcccaa aggtttccaa tgctacagcc
2581 tgggacagga accaggcagg gttcgccaaa gccacctgga aggggtctgc gtggcggaaa
2641 ctatccacta gccaaaggct gcactggctg ggccttttgg gtccagagaa gaccctgtat
2701 gtcaggatgg ggctagctag gacaaagcaa agaaatttgg agttactctt gtgtgccatt
2761 gtttccgact gcctttcaag aggtcttcta gaaagaggag tctggtggct tgcctataat
2821 ctcagcactt gagagactga ggcaggagga tcacaagtct gtctctgtct gtctgtctct
2881 tgactgaggc aggagaatca caaggagttt aatctctcct acactcacac acagtcactc
2941 gaattcgtgt agatgctggg aagagacacc acctgcctag gtttggtccc acttgactct
3001 gtatctctct tggggcttct cacagggctc caaggtgaaa gtggctgagc cggtgttaac
3061 ccaaaggctt cctcactgtc ctggctcccg aggggacctc agggtgccat tagccaaact
3121 tgccgtgcag cctctatctg catcgaggtt ccctctcatt gtggacgctg tatgacgagg
3181 gcaagccaga ggtctctgtt gcctcttccc catgccagaa aaagcaattc cataattcta
3241 tctttttaaa agaatgagag cctttcagag ctcgatgctg gatttccagg tcttttgggg
3301 gttttgtttt gttttgaaac agactcctat acagcccagg gtggccctca aactccctac
3361 atagccaagg ttgaccttga atggctagtc ctcttgccct tgcccccaag caatgggatt
3421 acaggcctcc tgcaccaagc ccattttttt cttcaaaaat atgtatttgt cgaacacagg
3481 tgcggcgggg catacctgtg atcccagcaa ttgggagact gagacaggag gatccaacct
3541 tcaaagctac atggtaagaa catactgagt ttgttttaaa gcatgtgtgg ggttgggata
3601 tggctcagtc tatgaagggc ttcctgggaa agcatgaggg cctgtgttca tattcccaga
3661 atgcacctca aaaatgctga gctcaacaat aaatggctat catccctgca ctagggagca
3721 agagacagaa ggacctcaag ggacatccag gggcctctgg aacctcaggg gacttctggg
3781 aacctctggg gacctcagag cctccggggt tctctggcca gccagttgga ctgaatcagg
3841 gtgctcctgg ttcagtgcaa gaccctgcct caaaaatagt gggcagctga ggaggctact
3901 gactgatgtt gacctctggt ttctccacac acacacacac acacacacac acacacacgc
3961 acgcacgcac gcacgtgcgc gcgcacgcac acacacacac atgtttaagt aatatataat
4021 agggcaaaat gctgagcacg gaggggtgct gtggcccgga gggtcactct tcacaggtac
4081 cccatttggc ccattttgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
4141 tgtgtgtgtg ctgacatact ctgagctcat gggaacaggt cagcccgggt tggttcctga
4201 ggactttgca gaaacagacc ctggctgacc ctggctgtgc tttgttccca tcttgtggcc
4261 tcattctgag ccagtttgaa caagcccctc cctctgaact ttagcccaac gctgcagcct
4321 aaagatgttt ctgagcttgt gaccttctaa ctttgggcca ctgggtagtt ggagctgagc
4381 tttgatttgg tgtcctttcc ttatcattat gggtatgaaa gagtggtcct agagcccagg
4441 agggcagcct ctcttgaccc tctgtatctc ctctctgccc ccagccatgg ctgcccagga
4501 gtccctgcac gtgaagaccc cactacgtga cagcatggca ttgtccaaag tggccggcac
4561 tagtgtgttc cttaagatgg acagctctca gccctctggc tccttcaaga tccgaggcat
4621 tgggcatctc tgcaagatgg tacaaggcag ggtggcatac tggcaggaga ggcagtccct
4681 cctacctgac agctgtagag gcaggtgtgc agatacacac ccaggattcc aaacggaggc
4741 aggaaggtgg aaagtgaatg gtatcccaga gtgcatagca agaacctgtc tctaaggaat
4801 aataataatt ttagggactg cagttgagac agctcggcgg ctgagagcac tggctgcttt
4861 tgcaggggac ttgagctcag ttcccgcaac cccatggtgg ctcacgatca actataactc
4921 cagctccagg agatccaaca ctctcttctg atttcccgga gcaactgcat cacatgcata
4981 taattcaaaa taagtaaata ttgggctgga gcgataattc agtggttagg aatacttggg
5041 gctctttcag aacagccatg ctcaccctca gcatccaagt gagcgagggg ctgtaactcc
5101 agctgcaggg catcaaatgc tctcctctgc cctctacagg caatacgtac acacagacac
5161 aagtgcacat aaagaaaaca catctttttt ttttcttttt aagaattttt atttatttta
5221 cttatatgag cacactgttg ctgtcttcag aaacaccaga agagggcacc agatcccatc
5281 gcagatggtt gtgagccacc atgtggttgc tggggattga actcaggacc tctggaagag
5341 cagtcagtgc tcttaacccc taagccatct ctccagccca agaaagcaca tcctaaataa
5401 ataaataaaa tatgttttaa agaaaataat aattttagaa taggtttcac acatcagggc
5461 tctctctggc taaggggtgc ccaccctaca gactgacacc tgcctcctta ccccagttaa
5521 tcaccttggg ggagatgagc ctgagagagt ggttcagata ccaagtgggc aagctcagat
5581 gttccagtgg tgaggacgtg tcctaggcag ggacttgggg gtggcctgat ccttcctctt
5641 gtccccacag aaggcaaaac aaggctgtaa acatttcgtc tgctcttcag gtgagtgccc
5701 agttcgtttt ctttcccttc ctaccctgtt ctgtgtgtcc tgtggcccag caccaggcat
5761 tctccctgga ctctgggctc tgcaacaaca catccattcg tagtcgtcca gatttggggt
5821 tccagaatga ggggcagaag tcactctgga gatgagcagc cccacgtgag gtcccaggcc
5881 ctccttcctg atacaccctc tccactgaca gcgggcaacg cgggcatggc gactgcctat
5941 gctgccagga ggctgggcct cccagccact attgttgtgc caagcaccac acctgccctc
6001 accattgagc ggctgaagaa cgaaggggcc acagttgaag tggtgggaga ggtgagtgca
6061 gacctattgt gggcagcaga gctggcgggt ggaggtgggg ggctgataac tggatagagc
6121 cctcgttcat ctcaatctct tcctgccccc acccctgcag atgctggatg aggccatcca
6181 actggccaag gctctggaaa agaacaaccc aggttgggtg tacatctccc ccttcgatga
6241 ccctctcatc tggtaagttg gagccacccc actccctact gcatgtgtgg tctctgctca
6301 tgttctcgcc ggcacaccag ccatgagggg tccccagatg cagagattcg gagagatcga
6361 ctcatcttgg ggtggctagg agcaaactaa ctagggaacg catcggtgga ggtggctttc
6421 atgtgccagc atctgccctg aacaactgaa gcttggcccc tgggaaccct gggagtcggt
6481 ggggaatgag catctaagga tgtgtccact ggtgggcagg aaatgggggt ttatctacca
6541 cacccacagc catctcctct ctgggagtgc gtggggtgag ggggtggggg ggtggggtct
6601 tgtctcctac cctgtgccct gagcagcagg gaggtcagag gtcaggttca tcatggcctg
6661 gcatagaggg aaaaacagac cttagctggt atctttgacc agcccttgtg tcttcaggaa
6721 gccctgacct gacctgccac ccctctcttg cccagggaag gccacacttc ccttgtgaag
6781 gagctgaagg agacactgag cgccaagccc ggggccattg tgctgtctgt gggcggtgga
6841 ggcctgctgt gcggagtggt ccaggggctg cgggaggtgg gctgggagga tgtgcccatc
6901 atcgccatgg agaccttcgg cgcccacagc ttccacgctg ccgtcaagga aggaaagctg
6961 gtcaccctgc ccaagatcac caggtgagcc cggggcacct ctccagcaca caggcggtgg
7021 agctgagcct ttggtccttt gcccgaagcc acactctcgc gcgccgtctg ggccttgaac
7081 gtgagtccgt tctttatgtg acagtgctta agtgacgtcc ttcgcttctt gaggtcctca
7141 cgcctcattt cttttgctgc tgtttgatct ggcctccgaa atgtgccaga ccctggctgg
7201 tcctggactc agcctgggag aaaacaatct ctggcctgca aagaatttat aaccaaaccc
7261 caccgcggcg gctcaaacca aactgagctc tagttctatt taagactatt aggggcaact
7321 cttcgaacca ggggctcagt tcctttagtc tcttgtcccg ccactgagag tgttgaccta
7381 gggtccaaag tggctgcttt ggtgccagcc accgcacaca cactccctct gaaaagaggc
7441 taagcaagag cagaagtgtt tctaaacttt aaagaccaag tagagctgct ccccagctga
7501 caatggggtc acacccaatc tttaaccatt cgttaaagat tgctatgaat gagttgaacc
7561 tggtctgctg gacgccttac ctaagctttt tggcacacgg tacagaactg gctgcttctt
7621 gctgataggc tgatgggaga ggtctccctc aaggctgcca ctgggcaacc caagagcgga
7681 ttgtactgca aacccatagt ctgagaaaag gtctgagttc aactctcaaa gtttggtttg
7741 taccaaatgt ggattttttt ttttttgaca ccacaacgtt gaactctcat agaccaaccc
7801 tcagaaatca gagctgtctg tacttccctc ttatcatgca ctgggcagtg cttggtcaca
7861 tgaccatacc tagctgcaag ggaggcaggg caaggttcac actaggcatc cacaagaaca
7921 gctagaaggg atttctagag agaggatggc ttctgtcata ggtagggaac accgaatcag
7981 ttaaaagact cttccatatt tttgggcacc atggtgagac tgatgccatc ctgctaccac
8041 tattctttcc tgccgatagg aatacagatg cagtagctgg cactcaagca gccatttttg
8101 gaccctaagt taatatgacc ctggggcaga tattgcctca tctgtttccc actctataca
8161 acttggagct tggaaagtgt gtgacagaca cctgatactt taggaaggac tagttctccc
8221 tgtttgttag agtgtgggag ggctgtctga gagcctcaac taatccatga gaccaaggag
8281 tccctctggg agtctccctg gaagaggtag caagtgagca aagcaggcgg aggttacaag
8341 ctggcaggct gggggtgggg gtggggcagc agagtccttc tggtatctga atcaggccag
8401 tttgatatcc tagaccactg tacaggttcc tggggctggg cagggttgcc cactcccact
8461 gttcacctgt agtccccgca tctcacgtgc acccttctac cttgtctctc cccatgtcca
8521 cccccctctc attcccacct cccagtgttg ccaaggcctt gggtgtgaac actgtggggg
8581 cacagaccct gaagctgttt tacgaacacc ccattttctc tgaggtcatc tcagaccagg
8641 aggctgtgac tgctatcgag aagttcgtag gtatgttctg tgggatcttt ttgtccttga
8701 ttttctccct cctcagccta gaccatctca tgaaaggaaa ctaaagccag tcagtggtaa
8761 acgcaaaagc tgctcgagaa aacatgaacc tggttaacca tgatagcagg gaggacaaac
8821 tagttttata agtgccagtt ttgagctttc tggtagccag agtcaaaagg gaaagggcca
8881 agatgaggtg atctctctgg gcttagcctg ggagatggtc aaaggaacga gagtagtgca
8941 cactgccatt aataacttca gcttgctaca ccactagaga gcaaccttct caggggccca
9001 ggaaccccaa gcacagactg tagaaaccga gactgggttc agaacaaaca gtcctggcca
9061 cagtgactga cgagagctga cgagccccct cccctacaga cgatgagaag atcctggtgg
9121 agcccgcgtg tggcgctgcc ctggctgcag tgtacagcgg tgtggtgtgc aggctgcagg
9181 ctgagggccg actgcaaacc ccactggcct cgctggttgt cattgtgtgt ggtggcagca
9241 acatcagcct ggcacagctg caggcactca aggcacagct gggcctgaat gagctactca
9301 agtgatatct gctgctgccc tggccaccct gaggggtcac cagcacccct gagtaggctg
9361 ggtgggcgtc cgcctgacag tggcccaccc tcctttatcc atgtttataa tatgcacttt
9421 ttcattgtaa ataaaaatta atatatatat gtttataaag caaagatctt ttgagctttg
9481 ttattgacat ggggtctatg tgcagcccag gctggcttca aactggagat ccaagcttgg
9541 gtgaggtcga ctctagagga tcgatccccg ggcgagct
//