GenBank-Updates@genbank.bio.net (02/09/91)
LOCUS RATTHYPOMU 237 bp ss-mRNA ROD 09-FEB-1991
DEFINITION Rat truncated thyroid peroxidase mRNA, 3' end.
ACCESSION M57705
KEYWORDS thyroid peroxidase.
SOURCE Rat Thyroid stimulating hormone (TSH) stimulated FRTL5 cell, cDNA
to mRNA, clone MD14.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 237)
AUTHORS Derwahl,M., Seto,P. and Rapoport,B.
TITLE An abnormal splice donor site in one allele of the thyroid
peroxidase gene in FRTL5 rat thyroid cells introduces a premature
stop codon: Association with the absence of functional enzymatic
activity
JOURNAL Mol. Endocrinol. 4, 793-799 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 1..142
/gene="thyroid peroxidase"
/codon_start=2
/partial
/product="truncated thyroid peroxidase"
exon 1..112
/note="wild-type exon"
/gene="thyroid peroxidase"
/codon_start=1
/partial
mutation 113..>
/note="g in wt; a in truncated thyroid peroxidase gene.
This changes a splice donor site to a readthrough
sequence."
/gene="thyroid peroxidase"
intron 113..167
/note="wild-type intron"
/gene="thyroid peroxidase"
exon 168..237
/note="wild-type exon"
/gene="thyroid peroxidase"
/codon_start=1
/partial
BASE COUNT 56 a 87 c 45 g 49 t
ORIGIN
1 catcgatcat gacattgctc tcacaccaca gagcaccagc acagcagcct tctggggagg
61 tgtcgactgc cagttgacct gtgagaacca aaacccctgc ttccccatac agattctaaa
121 tggacccaag agccgaaagt gacatccagt ctcccccttt gccacagctt ccctcaaact
181 cctcacggac cactgcatgc ctacctttct accgctcctc agccgcctgt ggcactg
//GenBank-Updates@genbank.bio.net (03/02/91)
LOCUS RATTHYPOMU 237 bp ss-mRNA ROD 02-MAR-1991
DEFINITION Rat truncated thyroid peroxidase mRNA, 3' end.
ACCESSION M57705
KEYWORDS thyroid peroxidase.
SOURCE Rat Thyroid stimulating hormone (TSH) stimulated FRTL5 cell, cDNA
to mRNA, clone MD14.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 237)
AUTHORS Derwahl,M., Seto,P. and Rapoport,B.
TITLE An abnormal splice donor site in one allele of the thyroid
peroxidase gene in FRTL5 rat thyroid cells introduces a premature
stop codon: Association with the absence of functional enzymatic
activity
JOURNAL Mol. Endocrinol. 4, 793-799 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 1..142
/product="truncated thyroid peroxidase"
/gene="thyroid peroxidase"
/codon_start=2
/partial
exon 1..112
/note="wild-type exon"
/gene="thyroid peroxidase"
/partial
mutation 113..113
/note="g in wt; a in truncated thyroid peroxidase gene.
This changes a splice donor site to a readthrough
sequence."
/gene="thyroid peroxidase"
intron 113..167
/note="wild-type intron"
/gene="thyroid peroxidase"
exon 168..237
/note="wild-type exon"
/gene="thyroid peroxidase"
/partial
BASE COUNT 56 a 87 c 45 g 49 t
ORIGIN
1 catcgatcat gacattgctc tcacaccaca gagcaccagc acagcagcct tctggggagg
61 tgtcgactgc cagttgacct gtgagaacca aaacccctgc ttccccatac agattctaaa
121 tggacccaag agccgaaagt gacatccagt ctcccccttt gccacagctt ccctcaaact
181 cctcacggac cactgcatgc ctacctttct accgctcctc agccgcctgt ggcactg
//