GenBank-Updates@genbank.bio.net (03/01/91)
LOCUS HUMS100B1 3080 bp ds-DNA PRI 01-MAR-1991
DEFINITION Human S100 protein beta-subunit gene, exon 1.
ACCESSION M59486 J05600
KEYWORDS S100 protein beta subunit.
SEGMENT 1 of 3
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3080)
AUTHORS Allore,R.J., Friend,W.C., O'Hanlon,D., Neilson,K.M., Baumal,R.,
Dunn,R.J. and Marks,A.
TITLE Cloning and expression of the human S100-beta gene
JOURNAL J. Biol. Chem. 265, 15537-15543 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 2971..3041
/number=1
/gene="S100-beta"
BASE COUNT 756 a 792 c 795 g 737 t
ORIGIN
1 tatgagttct gcacaggcca aagtggccag ttaaatgggt ttgtaagaag tgtcacagtg
61 cctgcttatt tcaacccttt aatggtggca ttaatctcca aagctctttc agagattcag
121 tatttctgga taagaagggg aagttctggg actttcacta aacttctcct accatcatgg
181 tcctcatctc atacgtaaga gagccagtga ggggatttag ctagtgtatg tttgtttcaa
241 ttatacaacc aggaactgaa aaactaacta tagggagaat agtgtaccaa ctgggccccc
301 tgtgagtcgg tctcatgtta gaacctctat caagtgaaga actgaccatc acaagtttct
361 gctttgactg gtgagccaca gtgccatttt tggttcccag gaatttatgt caattgaggc
421 aatccctgag acatctaggt tacttccttt tcattagttg atggctgcag gacacttcag
481 aaaaggtgtg gaagagggtt tatggtattc tttctcacta gcacagattc tttctcaagg
541 ggccttggct tctcccttca atcaagatgc tctaggtctg acccaactta ggtctggaaa
601 ctcggagaga gcccatgatc tccactgtgg tgattcaagt taggtacttc ggtgaccaga
661 cctagaggtt ttcctgttgt gtggattaaa gactactcta gcgactgtcc atctcttcat
721 tctaaggaac actgtgagca attcaccact gccaaaaatc tctgtggacc aaggcattct
781 gattatcggt gtgttccttc tgctgtttat ggctgacatg cccaccttgt cttagcctgc
841 tactctgaaa tattatcgtc ccgctgaaat cagaggtcta gtctagcaat ccatatggtc
901 atatgtaggc tacagaccat ggaacttttc aggtgttcca ctcactcaat aatgcatttc
961 tcattactta gcgaagggtc ttcctgtgga atgtagctgc agggggtggg tgaatgtggg
1021 agtcacacat gattggatct ggtggctgtc cagtctaatg ggataagatt aaaactgagg
1081 gtcaggacag gtaagccagg tgatcaggaa gtgtgaaggt cagggaaaaa cacccagaac
1141 aaccctgcaa agtagggact acggtcaccc ctttcacaga aaggcttagg aatttatcca
1201 aagtcaaacc actgttaaat ggtggagcca agattcagac ccagcaattg taggaatctg
1261 tgggaagctg gtgaggttgt atccacgagc tcctggggag cctgggcaaa gaataccatc
1321 ctggggcccc agagcgcttg aaagcccttc tcctccctgt ggcagatcct ctctctcagc
1381 ctgcttccaa gacctgggaa cagggtggac ccacggcccc acacttgcca tcccaggaag
1441 ctgcagtgtg cagagggcag gcccggctgg gccctcctgc tgaacgcagt gccctaagca
1501 caggtgtacg gtcattgcat gagtggattt caaactattt ttaacccctg caggagcagg
1561 ctagagcgtt ttctatggac actgaagggt taatccagag ctcaggttgc cactctgggg
1621 aagtggtcag cacttacagg aatggtccct ccaacatctg agcgaggaag gggcacagag
1681 cacagttgtg ccttccttgg gcctgggcaa gctctgtgct tcacagagca agcctgtgtc
1741 agatccttca gcagagacca cagccagggg tggtgaagcc gatgaggaag tgagggccaa
1801 ccacactgct caggctgttc ctcacaggag gctggggcag gctgagccac gcaagaccac
1861 agctctcagc cctgtgctat ttccagggca cacttacaga tcctgaatgg tagagaacgt
1921 cctggataaa acaatgacag caagacagcc atgtacacag atatcttgtg ggaaaccctt
1981 tcacggccac tttgaaactg ggttgggaga aggacgtgat gctgggtcag gcatccattg
2041 gggaccatgg acatttttgg agagtttggg ccaatgttct tgtgtaattt gtcagaagga
2101 acacctactt cttcattctt gtgaagaaga acccataaac tggcccccgt gttcagaggc
2161 tccagtcgag cgagttgagg ggacagctgg acttctcctt cctcaggctg gctggaggct
2221 tcagcaaggg ggcacaccgt ccacacgcct ctgtaaaaca gcgttcgaac gggacatctc
2281 taaggcatcg tccaactctg agagtctgtg accttccacc ctggggtgga gggaaaggcc
2341 ttgggataca gtccacacat cacgttttcc cctaaaagta ccacccgttt tagtccctgc
2401 agacactggc ctcagcagct tctctgaggc agccccgttg agcccagggc tgaccacaga
2461 caagcactac tgtccacaga acttcacgcc cagtggggcc agacttggag gatggcagag
2521 gagagaagct ccaggggcct ctccattaga aaccaacttg caggccactt aatctcctat
2581 gctcagcctg tacttggaag ctgcttgttc ttggctgcac atttgctttg tttgaatcaa
2641 ttaatccaag tctctctcct ctccccaccc ccaaccttgc ctttagggtg acatcaatat
2701 tcatgtaata aagaaatcgc acaaaaagct gactccccac ttcctgccct acaggccctt
2761 ttttcttcct cagcccatgt gcaatcctgg ctcccagcaa gtccccgggg ctgcttggtc
2821 aatgcagccc tgtgtgcagg cctggcagcc ctgccacccc gttcggctcc cattggctgc
2881 cacggcctgc agtgggctgt caccagggtt catccatcct ccctgggcag agggcagagg
2941 gaataagagg ctgcctctgc ccaccagtcc tgccgcccag gacccgcagc agagacgacg
3001 cctgcagcaa ggagaccagg aaggggtgag acaaggaaga ggtgagaaag agccaggcca
3061 agaggacgct caggaagaaa
//GenBank-Updates@genbank.bio.net (03/02/91)
LOCUS HUMS100B1 3080 bp ds-DNA PRI 02-MAR-1991
DEFINITION Human S100 protein beta-subunit gene, exon 1.
ACCESSION M59486 J05600
KEYWORDS S100 protein beta subunit.
SEGMENT 1 of 3
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3080)
AUTHORS Allore,R.J., Friend,W.C., O'Hanlon,D., Neilson,K.M., Baumal,R.,
Dunn,R.J. and Marks,A.
TITLE Cloning and expression of the human S100-beta gene
JOURNAL J. Biol. Chem. 265, 15537-15543 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
protein_bind 2663..2670
/note="AP-2 binding site"
protein_bind 2689..2696
/note="CRE binding site"
repeat_unit 2740..2750
/rpt_family="beta-globin"
repeat_unit 2768..2777
/rpt_family="beta-globin"
CAAT_signal 2872..2876
/gene="S100-beta"
repeat_unit 2924..2933
/rpt_family="beta-globin"
repeat_unit 2931..2940
/rpt_family="beta-globin"
TATA_signal 2942..2946
/gene="S100-beta"
misc_feature 2946..2957
/note="S100 protein element SPE"
repeat_unit 2954..2963
/rpt_family="beta-globin"
exon 2971..3041
/number=1
/gene="S100-beta"
/evidence=EXPERIMENTAL
protein_bind 2973..2978
/note="SP1 binding site"
intron 3042..3080
/gene="S100-beta"
BASE COUNT 756 a 792 c 795 g 737 t
ORIGIN Chromosome 21q22.2-21q22.3.
1 tatgagttct gcacaggcca aagtggccag ttaaatgggt ttgtaagaag tgtcacagtg
61 cctgcttatt tcaacccttt aatggtggca ttaatctcca aagctctttc agagattcag
121 tatttctgga taagaagggg aagttctggg actttcacta aacttctcct accatcatgg
181 tcctcatctc atacgtaaga gagccagtga ggggatttag ctagtgtatg tttgtttcaa
241 ttatacaacc aggaactgaa aaactaacta tagggagaat agtgtaccaa ctgggccccc
301 tgtgagtcgg tctcatgtta gaacctctat caagtgaaga actgaccatc acaagtttct
361 gctttgactg gtgagccaca gtgccatttt tggttcccag gaatttatgt caattgaggc
421 aatccctgag acatctaggt tacttccttt tcattagttg atggctgcag gacacttcag
481 aaaaggtgtg gaagagggtt tatggtattc tttctcacta gcacagattc tttctcaagg
541 ggccttggct tctcccttca atcaagatgc tctaggtctg acccaactta ggtctggaaa
601 ctcggagaga gcccatgatc tccactgtgg tgattcaagt taggtacttc ggtgaccaga
661 cctagaggtt ttcctgttgt gtggattaaa gactactcta gcgactgtcc atctcttcat
721 tctaaggaac actgtgagca attcaccact gccaaaaatc tctgtggacc aaggcattct
781 gattatcggt gtgttccttc tgctgtttat ggctgacatg cccaccttgt cttagcctgc
841 tactctgaaa tattatcgtc ccgctgaaat cagaggtcta gtctagcaat ccatatggtc
901 atatgtaggc tacagaccat ggaacttttc aggtgttcca ctcactcaat aatgcatttc
961 tcattactta gcgaagggtc ttcctgtgga atgtagctgc agggggtggg tgaatgtggg
1021 agtcacacat gattggatct ggtggctgtc cagtctaatg ggataagatt aaaactgagg
1081 gtcaggacag gtaagccagg tgatcaggaa gtgtgaaggt cagggaaaaa cacccagaac
1141 aaccctgcaa agtagggact acggtcaccc ctttcacaga aaggcttagg aatttatcca
1201 aagtcaaacc actgttaaat ggtggagcca agattcagac ccagcaattg taggaatctg
1261 tgggaagctg gtgaggttgt atccacgagc tcctggggag cctgggcaaa gaataccatc
1321 ctggggcccc agagcgcttg aaagcccttc tcctccctgt ggcagatcct ctctctcagc
1381 ctgcttccaa gacctgggaa cagggtggac ccacggcccc acacttgcca tcccaggaag
1441 ctgcagtgtg cagagggcag gcccggctgg gccctcctgc tgaacgcagt gccctaagca
1501 caggtgtacg gtcattgcat gagtggattt caaactattt ttaacccctg caggagcagg
1561 ctagagcgtt ttctatggac actgaagggt taatccagag ctcaggttgc cactctgggg
1621 aagtggtcag cacttacagg aatggtccct ccaacatctg agcgaggaag gggcacagag
1681 cacagttgtg ccttccttgg gcctgggcaa gctctgtgct tcacagagca agcctgtgtc
1741 agatccttca gcagagacca cagccagggg tggtgaagcc gatgaggaag tgagggccaa
1801 ccacactgct caggctgttc ctcacaggag gctggggcag gctgagccac gcaagaccac
1861 agctctcagc cctgtgctat ttccagggca cacttacaga tcctgaatgg tagagaacgt
1921 cctggataaa acaatgacag caagacagcc atgtacacag atatcttgtg ggaaaccctt
1981 tcacggccac tttgaaactg ggttgggaga aggacgtgat gctgggtcag gcatccattg
2041 gggaccatgg acatttttgg agagtttggg ccaatgttct tgtgtaattt gtcagaagga
2101 acacctactt cttcattctt gtgaagaaga acccataaac tggcccccgt gttcagaggc
2161 tccagtcgag cgagttgagg ggacagctgg acttctcctt cctcaggctg gctggaggct
2221 tcagcaaggg ggcacaccgt ccacacgcct ctgtaaaaca gcgttcgaac gggacatctc
2281 taaggcatcg tccaactctg agagtctgtg accttccacc ctggggtgga gggaaaggcc
2341 ttgggataca gtccacacat cacgttttcc cctaaaagta ccacccgttt tagtccctgc
2401 agacactggc ctcagcagct tctctgaggc agccccgttg agcccagggc tgaccacaga
2461 caagcactac tgtccacaga acttcacgcc cagtggggcc agacttggag gatggcagag
2521 gagagaagct ccaggggcct ctccattaga aaccaacttg caggccactt aatctcctat
2581 gctcagcctg tacttggaag ctgcttgttc ttggctgcac atttgctttg tttgaatcaa
2641 ttaatccaag tctctctcct ctccccaccc ccaaccttgc ctttagggtg acatcaatat
2701 tcatgtaata aagaaatcgc acaaaaagct gactccccac ttcctgccct acaggccctt
2761 ttttcttcct cagcccatgt gcaatcctgg ctcccagcaa gtccccgggg ctgcttggtc
2821 aatgcagccc tgtgtgcagg cctggcagcc ctgccacccc gttcggctcc cattggctgc
2881 cacggcctgc agtgggctgt caccagggtt catccatcct ccctgggcag agggcagagg
2941 gaataagagg ctgcctctgc ccaccagtcc tgccgcccag gacccgcagc agagacgacg
3001 cctgcagcaa ggagaccagg aaggggtgag acaaggaaga ggtgagaaag agccaggcca
3061 agaggacgct caggaagaaa
//