GenBank-Updates@genbank.bio.net (03/05/91)
LOCUS VACB13R 1275 bp ds-DNA VRL 05-MAR-1991
DEFINITION Vaccinia virus, B13R gene encoding serine proteinase inhibitor
(serpin), complete cds.
ACCESSION D00581
KEYWORDS serine proteinase inhibitor; serpin.
SOURCE Vaccinia virus (strain WR) DNA plasmid provided by Mike Merchlinsky
and Bernard Moss (National Institutes of Health, Bethesda, Md.,
U.S.A.).
ORGANISM Vaccinia virus
Viridae; ds-DNA enveloped viruses; Poxvirinae; Orthopoxvirus.
REFERENCE 1 (sites)
AUTHORS Kotwal,G.J. and Moss,B.
TITLE Vaccinia virus encodes two proteins that are structurally related
to members of the plasma serine protease inhibitor superfamily
JOURNAL J. Virol. 63, 600-606 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1275)
AUTHORS Smith,G.L., Howard,S.T. and Chan,Y.S.
TITLE Vaccinia virus encodes a family of genes with homology to serine
proteinase inhibitors
JOURNAL J. Gen. Virol. 70, 2333-2343 (1989)
STANDARD full staff_entry
COMMENT
[J. Virol. 63, 600-606 (1989)] sites.
They sequenced the region of the vaccinia virus genome adjacent to
the right inverted terminal repeat in [J. Gen. Virol. 70, 2333-2343
(1989)]. Kotwal and Moss
published an erratum in J. Virol in March 1990 changing all their
errors of the sequence so that the sequence in [J. Gen. Virol. 70,
2333-2343 (1989)] and that in [J. Virol. 63, 600-606 (1989)]
are now identical.
FEATURES Location/Qualifiers
misc_signal 39..48
/note="potential early transcriptional termination signal"
CDS 121..1158
/note="serine proteinase inhibitor (serpin)"
misc_signal 1162..1169
/note="potential early transcriptional termination signal"
BASE COUNT 405 a 220 c 252 g 398 t
ORIGIN
1 actacgtaaa ctgtttatac aagattgaaa ttatattctt ttttttatag agtgtggtag
61 tgttacggat atttaatatt agactatctc tatcgcgcta cacgaccaat atcgattact
121 atggatatct tcagggaaat cgcatcttct atgaaaggag agaatgtatt catttctcca
181 gcgtcaatct cgtcagtatt gacaatactg tattatggag ctaatggatc cactgctgaa
241 cagctatcaa aatatgtaga aaaggaggag aacatggata aggttagcgc tcaaaatatc
301 tcattcaaat ccataaataa agtatatggg cgatattctg ccgtgtttaa agattccttt
361 ttgagaaaaa ttggcgataa gtttcaaact gttgacttca ctgattgtcg cactatagat
421 gcaatcaaca agtgtgtaga tatctttact gaggggaaaa tcaatccact attggatgaa
481 ccattgtctc ctgatacctg tctcctagca attagtgccg tatactttaa agcaaaatgg
541 ttgacgccat tcgaaaagga atttaccagt gattatccct tttacgtatc tccgacggaa
601 atggtagatg taagtatgat gtctatgtac ggcaaggcat ttaatcacgc atctgtaaag
661 gaatcattcg gcaacttttc aatcatagaa ctgccatatg ttggagatac tagtatgatg
721 gtcattcttc cagacaagat tgatggatta gaatccatag aacaaaatct aacagataca
781 aattttaaga aatggtgtaa ctctctggaa gctacgttta tcgatgttca cattcccaag
841 tttaaggtaa caggctcgta taatctggtg gatactctag taaagtcagg actgacagag
901 gtgttcggtt caactggaga ttatagcaat atgtgtaatt cagatgtgag tgtcgacgct
961 atgatccaca aaacgtatat agatgtcaat gaagagtata cagaagcagc tgcagcaact
1021 tgtgcactgg tgtcagactg tgcatcaaca attacaaatg agttctgtgt agatcatccg
1081 ttcatctatg tgattaggca tgttgatgga aaaattcttt tcgttggtag atattgctct
1141 ccgacaacta attgttaacc atttttttta aaaaatagaa aaaacatgtg gtattagtgc
1201 aggtcgttat tcttccaatt gcaattggta agatgacggc caactttagt acccacgtct
1261 tttcaccaca gcact
//