GenBank-Updates@genbank.bio.net (03/07/91)
LOCUS MUSCTFR 6304 bp ss-mRNA ROD 07-MAR-1991
DEFINITION Mouse cystic fibrosis transmembrane conductance regulator (CTFR)
mRNA, complete cds.
ACCESSION M60493
KEYWORDS cystic fibrosis transmembrane conductance regulator.
SOURCE Mouse cDNA to mRNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 6304)
AUTHORS Yorifuji,T., Lemna,W.K., Ballard,C.F., Rozmahel,R., Plavsiv,N.,
Tsui,L.-C. and Beaudet,A.L.
TITLE Molecular cloning and sequence analysis of the murine cystic
fibrosis transmembrane conductance regulator (CFTR) cDNA
JOURNAL Unpublished (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
mRNA <1..6304
/product="cystic fibrosis transmembrane conductance
regulator"
CDS 139..4569
/product="cystic fibrosis transmembrane conductance
regulator"
/codon_start=139
BASE COUNT 1904 a 1223 c 1381 g 1796 t
ORIGIN
1 taattggaag caagtggcgt cacctcaggt ctgagtgaaa gggacgagcc aaaagcattg
61 gcctggtcct ggatatccag atgttgagtc caacctgggt ttagtcgaac acagacctca
121 ttgcctcacg gagacatcat gcagaagtcg cctttggaga aagccagctt tatctccaaa
181 ctcttcttca gctggaccac accaattttg aggaaagggt acagacacca cttggagttg
241 tcagacatat accaagcccc ttctgctgat tcagctgacc acttgtctga aaaactagaa
301 agagaatggg acagagaaca agcttcaaaa aagaatcccc agcttatcca cgcccttcgg
361 cgatgctttt tctggagatt cctcttctat ggaattttgc tatacctagg ggaagtcacc
421 aaggctgtcc agcctgtctt gctaggaaga atcatagcat cctatgatcc agaaaacaag
481 gtggaacgtt ccattgccat ttaccttggc ataggcttat gccttctctt cattgtcagg
541 acactgcttc ttcacccagc tatttttggc cttcatcgca ttggaatgca gatgagaaca
601 gctatgttta gcttgattta taagaagact ttaaagttgt caagccgcgt tcttgataaa
661 ataagtattg gacaacttgt tagtcttctt tccaacaacc tgaacaaatt tgatgaagga
721 cttgccttgg cacattttat atggattgct cctttacaag tgactcttct gatggggctt
781 ctctgggact tgttacagtt ctcagccttc tgtggccttg gtttactgat aatcctggtt
841 atttttcaag ctatcctagg gaagatgatg gtgaagtaca gagatcagag agctgcaaag
901 atcaatgaaa gactcgtgat cacatcagaa attattgata atatctattc tgttaaggca
961 tattgttggg aatcagcgat ggagaaaatg attgaaaact tgagagaggt ggagctgaaa
1021 atgacccgga aggcggccta tatgaggttc ttcactagct ctgccttctt cttttcaggg
1081 ttctttgtag tctttctatc tgtgcttccc tacacagtca tcaacggaat cgtcctacga
1141 aaaatattca caaccatttc attctgcatt gtcctacgta tgtcagtcac acggcagttc
1201 cccactgccg tacagatatg gtatgattct tttggaatga taagaaaaat acaggatttc
1261 ctgcagaaac aagagtataa agtactggag tataacttaa tgaccacagg cataatcatg
1321 gaaaatgtaa cagcattttg ggaggaggga tttggggaat tactggagaa agtacaacaa
1381 agcaatggtg acagaaaaca ttccagtgat gagaacaatg tcagtttcag tcatctctgc
1441 cttgtgggaa atcctgtgct gaaaaacatc aatttgaata tagagaaagg agagatgttg
1501 gctattactg gatctactgg atcaggaaag acatcactcc tgatgttgat tttgggagaa
1561 ctggaagctt cagagggaat tattaagcac agtggaagag tttcattctg ctctcaattt
1621 tcttggatta tgccgggtac tatcaaagaa aatatcatct ttggtgtttc ctatgatgag
1681 tacagatata agagtgttgt caaagcttgc caactacagc aggacatcac caagtttgca
1741 gaacaagaca acacagttct tggagaaggt ggagtcacac tgagtggagg tcagcgtgca
1801 aggatttctt tagcaagagc agtatataaa gatgctgatt tgtacctatt agattcccct
1861 tttggatatc tagatgtttt tactgaagaa caagtatttg aaagctgtgt ttgtaaattg
1921 atggccaaca aaactaggat tttggttaca tctaaaatgg aacacttaag gaaagctgac
1981 aaaatactaa ttttgcatca gggcagtagc tatttttatg ggacattttc tgagctacaa
2041 agtctacgtc cagacttcag ttcgaaactc atggggtatg atacttttga ccagtttact
2101 gaggaaagaa gaagttcaat tctaactgag accttacgca ggttctcagt agacgattcc
2161 tctgccccgt ggagcaaacc caaacagtcg tttagacaga ctggagaggt gggagaaaaa
2221 aggaagaact ctattctaaa ttcattcagc tctgtaagga aaatttccat tgtgcaaaag
2281 actccattat gtatcgatgg agagtctgat gatctccaag aaaagagact gtccctagtt
2341 ccggattctg aacaggggga ggctgctctg ccgcgcagca acatgatcgc caccggcccc
2401 acatttccag gcagaagaag acagtctgtt ttggatctga tgacgttcac acccaactca
2461 ggctccagca atcttcagag gaccagaact tctattcgaa aaatctcctt agtccctcag
2521 ataagcttaa atgaagtgga tgtatattca aggagattat cgcaagatag cacactgaac
2581 atcactgaag aaattaacga agaagattta aaggagtgtt ttcttgatga tgtgatcaag
2641 atacccccgg tgacaacatg gaacacatac ctacgatatt ttactctcca taaaggctta
2701 ctgctagtgc tgatttggtg cgtactggtt tttctggttg aggtggctgc ttctttattt
2761 gtgttatggt tgcttaaaaa caaccctgtt aacagtggaa acaatggtac taaaatttcc
2821 aatagctcct atgttgtgat catcaccagt accagtttct attatatttt ttacatttac
2881 gtgggagtgg ctgacacttt gcttgccctg agcctcttca gaggtttgcc gctggtgcat
2941 acgttaatca cagcatcaaa aattttgcac aggaaaatgt tacactccat tcttcacgcc
3001 cctatgtcga ccatcagcaa gctgaaagca ggtgggattc ttaacagatt ctccaaagat
3061 atagcaattt tggatgactt tctgcctctt accatttttg acttcattca gttggtgttc
3121 attgtgattg gagctataat agtcgtctcg gcattacaac cctacatctt cctagcaacg
3181 gtgccagggc tagtagtctt tattttactg agggcctact tccttcatac agcacagcag
3241 ctcaaacaac tggaatctga aggcaggagt ccaattttca cccaccttgt gacaagctta
3301 aaaggactct ggacacttcg agccttccga cgccagactt actttgaaac tctgttccac
3361 aaagctctga atttgcacac tgccaactgg tttatgtatc tggcaacctt gcgctggttc
3421 caaatgagaa tagacatgat atttgtcctc ttcttcattg ttgttacctt catctccatt
3481 ttaacaacag gtgaaggaga aggaacagct ggtattattc taactttagc tatgaatatc
3541 atgagtactt tgcagtgggc tgtgaactca agcattgata cagatagctt gatgcgatct
3601 gtgagcagag tgtttaagtt tattgatata caaacagaag aaagtatgta cacacagata
3661 attaaagaac tacctagaga aggatcatct gacgttttag tcattaagaa tgagcatgtg
3721 aagaaaagtg atatctggcc ctctggaggc gaaatggttg tcaaagacct tactgtgaaa
3781 tacatggatg atggaaatgc cgtattagag aacatttctt tttcaataag tcctggacag
3841 agggtggggc tcttaggaag aactggatca ggaaaaagta ctttgctttc agcattttta
3901 cgaatgttga acattaaagg tgatatagag attgatggtg tctcatggaa ttcagtgacc
3961 ttacaagaat ggaggaaagc tttcggagtg ataacacaga aagtatttat cttttctgga
4021 acattcagac aaaacctgga tcccaatgga aaatggaaag atgaagaaat atggaaagtt
4081 gcagatgagg ttggactcaa gtctgtaata gagcagtttc ctggacagct caactttacc
4141 cttgtggatg ggggttatgt gctaagccat ggccataagc aattaatgtg cttggcccga
4201 tcagttctca gtaaggccaa gatcatactg cttgatgagc ccagtgccca tctagacccc
4261 ataacatacc aagtcattcg acgagttcta aaacaagcct tcgctggttg cacagtcatc
4321 ctctgtgaac acaggataga agcgatgttg gattgccagc gatttttggt catagaagag
4381 agcaatgtct ggcagtacga ctcccttcag gcacttctga gtgagaagag tatcttccag
4441 caggccatta gctcctcgga aaagatgagg ttcttccagg gccgccactc cagcaagcac
4501 aagcctcgga cgcaaattac tgctctgaaa gaggagacag aagaagaagt tcaagaaacc
4561 cgtctctagt gctgggatgc tgaggaagca actcagtgca ctgagtccat tcccagaacc
4621 catgcagaat gaaaaaagcc aggcatttcc catgcttcta accccagtgc tggggacaca
4681 gagacaggtg gatccctggg gctctgtggc aagtgatcct agcccacaaa gagagttcca
4741 ggctgggcac ctgagggaca atacctgtgg atatactctt gcttccacat gcaagtacat
4801 atacacatgc atgcacatta gtggacatac acacagaaaa gcaaagaaga aggaaagagg
4861 gaagaaaata gtgcaaataa ttgcaaaacg atcatgtatg gagtctgctc atggacttag
4921 aggaggtgaa ctctactacc tgtgcctttg aaagaagggt gaagcctgcg acttgctctt
4981 taagagactg ttttggaaga gagttcaaaa acgttcatat gggtatgggt aactgacttt
5041 cccagcagta gtcaaattgt ttgaacttca gatagttgat aatgaccact tgtgtattgc
5101 aaggcagatt tttctgaaaa catttgcccc ctaatagtag ctgaaaaagc agctataaat
5161 gccaaccagg ttagtcattc ggcttattgt tcagtacagc tggttaattt gcattattga
5221 agaactgaaa ttatagtgct tagatataga acaaagtaaa gagaactaaa aacagtgtct
5281 tatataactc aaagcccaac ttactttcct ctaagatatg tattgccttc tatacatttt
5341 ctgccccatt ccaagcaaat gttagaatat tatacaaaat actgggtggt attgattgaa
5401 agatgcccga catctggtga tctagtaacc catcaggatt aaggatatcc aggtcttgga
5461 aattaaggtt aagaccatct agccttacta ccgtacagct aaacattctt attaccagaa
5521 taagacctag gaaaagaact gtttcagtcc cataaagtgg cctggataat ttccttgata
5581 tggaaatcga cacacttatg ttcccagaaa gcaacagatc tttaagactt ctgaagtgaa
5641 ggaaggttgt gttagtgcaa actagtgcag cccagtgcca ggtccaggag ttaacatgta
5701 gacaggccat ggactgtgtg ggtagatgct catggaaatg tgcagtagta tgttcatgtg
5761 ctctcagcta gctgtgtgta cttcaaactg tctccacaga gttgttgggg agacactctg
5821 aaaaagaatt aattgtgaat tagttttata tactttgttt tataatttgt gatgcaaatg
5881 aaaatttctc tgggaaatat ttattttagt aataatgttt caaactcata tataacaatg
5941 ctgtatttta agaatgatta cataatgact tatatttgta taaaataatt tttatatttg
6001 aaatgttaac tttttatagc actagctatt ttaaaacagg ggagtgagga ggacagggat
6061 gataaggatc attcaacttc atgttgtgaa gacgagctga tgtaaatctt gtacccatct
6121 gtgtggttct cagacaacac atgctctctt ttaatgcagc tttgaagaag atggtaccaa
6181 aggttaagac ggccccctga tgggcacatc aacttctgaa ctgcaaacta agctttagag
6241 gaatgtatta tatttattac tgtaatagaa tatcatgtgt caataaaatc cttttatttg
6301 tgtg
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