GenBank-Updates@genbank.bio.net (03/08/91)
LOCUS HUMHBEGF 2360 bp ss-mRNA PRI 08-MAR-1991
DEFINITION Human heparin-binding EGF-like growth factor mRNA, complete cds.
ACCESSION M60278
KEYWORDS heparin-binding EGF-like growth factor.
SOURCE Human histiocytic lymphoma derived cell, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2360)
AUTHORS Higashiyama,S., Abraham,J.A., Miller,J., Fiddes,J.C. and
Klagsbrun,M.
TITLE A heparin-binding growth factor secreted by macrophage-like cells
that is related to EGF
JOURNAL Science 251, 936-939 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 262..888
/product="heparin-binding EGF-like growth factor"
/codon_start=262
sig_peptide 262..318
/codon_start=262
mat_peptide 742..813
/product="heparin-binding EGF-like growth factor"
/evidence=EXPERIMENTAL
/codon_start=742
BASE COUNT 599 a 579 c 605 g 577 t
ORIGIN
1 gctacgcggg ccacgctgct ggctggcctg acctaggcgc gcggggtcgg gcggccgcgc
61 gggcgggctg agtgagcaag acaagacact caagaagagc gagctgcgcc tgggtcccgg
121 ccaggcttgc acgcagaggc gggcggcaga cggtgcccgg cggaatctcc tgagctccgc
181 cgcccagctc tggtgccagc gcccagtggc cgccgcttcg aaagtgactg gtgcctcgcc
241 gcctcctctc ggtgcgggac catgaagctg ctgccgtcgg tggtgctgaa gctctttctg
301 gctgcagttc tctcggcact ggtgactggc gagagcctgg agcggcttcg gagagggcta
361 gctgctggaa ccagcaaccc ggaccctccc actgtatcca cggaccagct gctaccccta
421 ggaggcggcc gggaccggaa agtccgtgac ttgcaagagg cagatctgga ccttttgaga
481 gtcactttat cctccaagcc acaagcactg gccacaccaa acaaggagga gcacgggaaa
541 agaaagaaga aaggcaaggg gctagggaag aagagggacc catgtcttcg gaaatacaag
601 gacttctgca tccatggaga atgcaaatat gtgaaggagc tccgggctcc ctcctgcatc
661 tgccacccgg gttaccatgg agagaggtgt catgggctga gcctcccagt ggaaaatcgc
721 ttatatacct atgaccacac aaccatcctg gccgtggtgg ctgtggtgct gtcatctgtc
781 tgtctgctgg tcatcgtggg gcttctcatg tttaggtacc ataggagagg aggttatgat
841 gtggaaaatg aagagaaagt gaagttgggc atgactaatt cccactgaga gagacttgtg
901 ctcaaggaat cggctgggga ctgctacctc tgagaagaca caaggtgatt tcagactgca
961 gaggggaaag acttccatct agtcacaaag actccttcgt ccccagttgc cgtctaggat
1021 tgggcctccc ataattgctt tgccaaaata ccagagcctt caagtgccaa acagagtatg
1081 tccgatggta tctgggtaag aagaaagcaa aagcaaggga ccttcatgcc cttctgattc
1141 ccctccacca aaccccactt cccctcataa gtttgtttaa acacttatct tctggattag
1201 aatgccggtt aaattccata tgctccagga tctttgactg aaaaaaaaaa agaagaagaa
1261 gaaggagagc aagaaggaaa gatttgtgaa ctggaagaaa gcaacaaaga ttgagaagcc
1321 atgtactcaa gtaccaccaa gggatctgcc attgggaccc tccagtgctg gatttgatga
1381 gttaactgtg aaataccaca agcctgagaa ctgaattttg ggacttctac ccagatggaa
1441 aaataacaac tatttttgtt gttgttgttt gtaaatgcct cttaaattat atatttattt
1501 tattctatgt atgttaattt atttagtttt taacaatcta acaataatat ttcaagtgcc
1561 tagactgtta ctttggcaat ttcctggccc tccactcctc atccccacaa tctggcttag
1621 tgccacccac ctttgccaca aagctaggat ggttctgtga cccatctgta gtaatttatt
1681 gtctgtctac atttctgcag atcttccgtg gtcagagtgc cactgcggga gctctgtatg
1741 gtcaggatgt aggggttaac ttggtcagag ccactctatg agttggactt cagtcttgcc
1801 taggcgattt tgtctaccat ttgtgttttg aaagcccaag gtgctgatgt caaagtgtaa
1861 cagatatcag tgtctccccg tgtcctctcc ctgccaagtc tcagaagagg ttgggcttcc
1921 atgcctgtag ctttcctggt ccctcacccc catggcccca ggccacagcg tgggaactca
1981 ctttcccttg tgtcaagaca tttctctaac tcctgccatt cttctggtgc tactccatgc
2041 aggggtcagt gcagcagagg acagtctgga gaaggtatta gcaaagcaaa aggctgagaa
2101 ggaacaggga acattggagc tgactgttct tggtaactga ttacctgcca attgctaccg
2161 agaaggttgg aggtggggaa ggctttgtat aatcccaccc acctcaccaa aacgatgaag
2221 gtatgctgtc atggtccttt ctggaagttt ctggtgccat ttctgaactg ttacaacttg
2281 tatttccaaa cctggttcat atttatactt tgcaatccaa ataaagataa cccttattcc
2341 ataaaaaaaa aaaaaaaaaa
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