GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HL1PRO2 24 bp ss-RNA VRL 14-MAR-1991
DEFINITION Human T-cell lymphotropic virus type I (MT-1 cells), proviral 3'
LTR.
ACCESSION J02031
KEYWORDS long terminal repeat; provirus; terminal repeat.
SEGMENT 2 of 3
SOURCE HTLV1 proviral DNA from human cell line MT-1.
ORGANISM Human T-cell lymphotropic virus type I
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Oncovirinae; Type C oncovirus group;
Mammalian type C oncoviruses.
REFERENCE 1 (bases 1 to 24)
AUTHORS Seiki,M., Hattori,S. and Yoshida,M.
TITLE Human adult T-cell leukemia virus: Molecular cloning of the
provirus DNA and the unique terminal structure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902 (1982)
STANDARD full staff_review
COMMENT This is the beginning of the 3' LTR in the proviral sequence.
FEATURES Location/Qualifiers
provirus <1..>24
/note="HTLV1 proviral DNA"
LTR 10..>24
/note="HTLV1 proviral 3' LTR"
BASE COUNT 10 a 4 c 7 g 3 t
ORIGIN About 7.3 kb after segment 1.
1 agaggcagat gacaatgacc atga
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HL1PRO3 33 bp ss-RNA VRL 14-MAR-1991
DEFINITION Human T-cell lymphotropic virus type I (MT-1 cells), proviral 3'
LTR.
ACCESSION J02032
KEYWORDS long terminal repeat; provirus; terminal repeat.
SEGMENT 3 of 3
SOURCE HTLV1 proviral DNA from human cell line MT-1.
ORGANISM Human T-cell lymphotropic virus type I
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Oncovirinae; Type C oncovirus group;
Mammalian type C oncoviruses.
REFERENCE 1 (bases 1 to 33)
AUTHORS Seiki,M., Hattori,S. and Yoshida,M.
TITLE Human adult T-cell leukemia virus: Molecular cloning of the
provirus DNA and the unique terminal structure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902 (1982)
STANDARD full staff_review
COMMENT This is the end of the 3' LTR in the proviral sequence.
FEATURES Location/Qualifiers
LTR <1..15
/note="HTLV1 proviral 3' LTR"
provirus <1..15
/note="HTLV1 proviral DNA"
BASE COUNT 11 a 9 c 3 g 10 t
ORIGIN About 724 bp after segment 2.
1 gaaatttagt acacagcatt ccattccatt cca
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HL1MT2 221 bp ss-RNA VRL 14-MAR-1991
DEFINITION Human T-cell lymphotropic virus type I (MT-2 cells), 3' LTR.
ACCESSION J02028
KEYWORDS long terminal repeat; provirus.
SOURCE HTLV1, cDNA to viral RNA, from human cell line MT-2.
ORGANISM Human T-cell lymphotropic virus type I
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Oncovirinae; Type C oncovirus group;
Mammalian type C oncoviruses.
REFERENCE 1 (bases 1 to 221)
AUTHORS Seiki,M., Hattori,S. and Yoshida,M.
TITLE Human adult T-cell leukemia virus: Molecular cloning of the
provirus DNA and the unique terminal structure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902 (1982)
STANDARD full staff_review
COMMENT Also reported ([Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902
(1982)]) is the proviral sequence isolated from cell
line mt-1 (see separate entry). This sequence differs from the
proviral sequence only at bases 212 and 221.
FEATURES Location/Qualifiers
BASE COUNT 26 a 86 c 56 g 53 t
ORIGIN Unreported.
1 atctctcctt cacgcgcccg ccgccctacc tgaggccgcc atccacgccg gttgagtcgc
61 gttctgccgc ctcccgcctg tggtgcctcc tgaactgcgt ccgccgtcta ggtaagttta
121 gagctcaggt cgagaccggg cctttgtccg gcgctccctt ggagcctacc tagactcagc
181 cggctctcca cgctttgcct gaccctgctt gttcaactct g
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HL1PRO1 805 bp ss-RNA VRL 14-MAR-1991
DEFINITION Human T-cell lymphotropic virus type I (MT-1 cells), proviral 5'
LTR.
ACCESSION J02030
KEYWORDS long terminal repeat; provirus; terminal repeat.
SEGMENT 1 of 3
SOURCE HTLV1 proviral DNA from human cell line MT-1.
ORGANISM Human T-cell lymphotropic virus type I
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Oncovirinae; Type C oncovirus group;
Mammalian type C oncoviruses.
REFERENCE 1 (bases 1 to 805)
AUTHORS Seiki,M., Hattori,S. and Yoshida,M.
TITLE Human adult T-cell leukemia virus: Molecular cloning of the
provirus DNA and the unique terminal structure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902 (1982)
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Ahmed,Y.F., Gilmartin,G.M., Hanly,S.M., Nevins,J.R. and Greene,W.C.
TITLE The HTLV-I Rex response element mediates a novel form of mRNA
polyadenylation
JOURNAL Cell 64, 727-737 (1991)
STANDARD full staff_review
COMMENT This proviral sequence contains a 755 bp long terminal repeat.
Also reported is the 3' end of the viral RNA (see separate entry).
The complete proviral sequence from human peripheral blood cells
is also in a separate entry.
FEATURES Location/Qualifiers
LTR 21..774
/note="HTLV1 proviral 5' LTR"
provirus 21..>805
/note="HTLV1 proviral DNA"
BASE COUNT 167 a 271 c 195 g 172 t
ORIGIN Near SmaI site.
1 catttaatca agggcattcc tgacaatgac catgagcccc aaatatcccc cgggggctta
61 gagcctccca gtgaaaaaca tttccgagaa acagaagtct gaaaaggtcg cggcccagac
121 taaggctctg acgtctcccc ccggagggca gctcagcacc ggctcaggct aggccctgac
181 gtgtccccct gaagacaaat cataagctca gacctccggg aagccaccgg gaaccaccca
241 tttcctcccc atgtttgtca agccgtcctc aggcgttgac gacaacccct cacctcaaaa
301 aacttttcat ggcacgcata tggctcaata aactaacagg agtctataaa agcgtggaga
361 cagttcagga gggggctcgc atctctcctt cacgcgcccg ccgccctacc tgaggccgcc
421 atccacgccg gttgagtcgc gttctgccgc ctcccgcctg tggtgcctcc tgaactgcgt
481 ccgccgtcta ggtaagttta gagctcaggt cgagaccggg cctttgtccg gcgctccctt
541 ggagcctacc tagactcagc cggctctcca cgctttgcct gaccctgctt gctcaactct
601 acgtctttgt ttcgttttct gttctgcgcc gttacagatc gaaagttcca cccctttccc
661 tttcattcac gactgactgc cggcttggcc cacggccaag taccggcgac tccgttggct
721 cggagccgcg acagcccatc ctatagcact ctcaggagag aaatttagta cacagttggg
781 ggctcgtccg ggatacgagc gcccc
//