GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMP450SCC 2393 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human cytochrome P450scc gene, 5' end and promoter region.
ACCESSION M60421
KEYWORDS cytochrome P450scc.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2393)
AUTHORS Moore,C.C., Brentano,S.T. and Miller,W.L.
TITLE Human P450scc gene transcription is induced by cyuclic AMP and
repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187
through independent cis elements
JOURNAL Mol. Cell. Biol. 10, 6013-6023 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CAAT_signal 2262..2265
/gene="P450scc"
/partial
TATA_signal 2300..2304
/gene="P450scc"
/partial
mRNA (2328.2329)..2393
/product="cytochrome P450scc"
/gene="P450scc"
/partial
CDS 2391..2393
/product="cytochrome P450scc"
/gene="P450scc"
/codon_start=2391
/partial
BASE COUNT 609 a 523 c 639 g 622 t
ORIGIN
1 aagcttcagg gatggcagcc gcttgtgaga aaccctgagc atgagccact cagccaccca
61 gccacccagt cacccagcca cccagccacc cagtcaccca gaaaagctgc tcctgggtgc
121 tgcaccctcg gaagctgtga gataataaac atttattgtt ttaagccact aaattttggg
181 ataatttgtt aagcagcagt aaacagctaa tacattcagc cttgtttgga gtgagtgatg
241 tgtttctgga agctctttca gagaagtgag ggagctattc tcccagaagc cacagcaaac
301 ctttccctgt gtttcattgg cccaaactgg atcggctggc ctatgctgtg atgtgaccat
361 ggcgattgga gaggatgagg caataacctc cagcctgggc cacttctggg gaggcggtca
421 gtgcccacaa cactggggga ggtgcggagg cctgaacgga agttggggtg gctgccaaga
481 ggaccacaag ttcttccatg ccacatcgat tagggctcct tctgagggag gaatgtgggg
541 ctgcgtagaa caatgggatt gactttaagt cagaaagtta taaatgtcac ctcagtgctg
601 agacccttgg aggaaaaact agtccttgga agactgcttt tcttgtggaa gctcatcacc
661 ctgccgctgc tcgtgagaca ctgccttcct tggctgatgt cattccaggc tcaaggtcat
721 catggaggca aaacaggctt tctcatactc tctttatcag aaggttcatg actgatgagg
781 tagtggtcac tccagcggga agagcaacaa ccactcttga taagtacttt ttttttttct
841 tctaaaaact gttgctctaa atttgttgaa agtggttcaa cagtattgga gtctggggtc
901 aagtggctgt gtaaggacaa cttttgccat tgtgggtgat ctatgggctg acacatacaa
961 cagaagaggc caggaggatg tcactcgtgt gtgtgtgtgt gtgtgtgtgt gtgttggtaa
1021 cagctctatt gagatataat tcacacacca tacattcacc catttaaagt atgcaattca
1081 atggctttta gtgtatagag agttgttcaa taattaccac atatctttag aatattttca
1141 ttttcatcat cctaagaatc cctacacact ttatgtccca tcctctaatt cctctatccc
1201 cctagctcta agcaaccacc agtctatttt ctgtctgtta gatgtgtgtt ttaaatgcct
1261 tatttgccag aaaataagat tttggggaaa aaaagcaaga agtaccttcc aatgataagt
1321 ataaggtata gtgtagattg ctgtcatgaa atgctctaca tggcacatgt atgttttctg
1381 acctacacat ttttaccaag tgggctgtaa ttttgttgaa atgacttgaa aactctacag
1441 gtgactgacc cttgttgttt gggaaagtgg taggtgcagg gtgatggggg gtgggtgtgg
1501 gggctgacct gggctggaag gatgggtctg gggatatgat atgatgggag ggggtatgga
1561 agcagctctg aggggtttgc agcacagatc aagtgtgtgg acagggaaga gctgacatcc
1621 tgagttccgg atggcaacca gatttgccaa ggtcttagag tgtgtccaga gtggagcctg
1681 accacagacc tcagctcaag ggacccagag cccctctgag tcagctgtac tgaattacag
1741 ccccaaatct gggtcaactg gggagagacg acgaggatta gggttccaag gtgaaactgt
1801 gccattgcgc tccagcctgg gcaacaagaa tgaaactctc ttaaaataaa ataaaataaa
1861 atagcctaag gatgcatttc tcagaactta tccctgttgt tcaatgatgt gtgtctatac
1921 agtggggcca taactaagac gtatgttgcc caagctggca agatagctct gaccttctct
1981 tgggcccctc atttccccca aacacaggtt gtctgcagtc ttgaccaatg gctgccaggg
2041 catggactcc gctgcagggg ccagtgggag gccccagctc aggcaaaagc acaggcagat
2101 atttcaggag tctgctaggg ctggcactga gggcagagac agaggggtct ccctgtcctt
2161 tggagaacct cacgctgcag aaattccaga ctgaaccttg ataccgagta ggggaggagc
2221 tgtctgcggg tttgagcctg cagcaggagg aaggacgtga acattttatc agcttctggt
2281 atggccttga gctggtagtt ataatcttgg ccctggtggc ccagggctac agtcatccta
2341 gcagtccccg ctgaagtgga gcaggtacag tcacagctgt ggggacagca atg
//