GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS MUSTCAXK 479 bp ss-mRNA ROD 14-MAR-1991
DEFINITION Mouse T-cell receptor rearranged alpha-chain mRNA V-J-C region, 3'
end.
ACCESSION M31649
KEYWORDS T-cell receptor; T-cell receptor alpha-chain; constant region;
joining exon; variable region.
SOURCE Mouse (strain CBA/J; haplotype H-2k) spleen T-suppressor lymphocyte
cell line BVI, cDNA to mRNA, clone BVI/5.alpha-2.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 479)
AUTHORS Heuer,J., Degwert,J., Pauels,H.-G. and Koelsch,E.
TITLE T cell receptor alpha and beta gene expression in a murine
antigen-specific t suppressor lymphocyte clone with cytolytic
potential-1
JOURNAL J. Immunol. 146, 775-782 (1991)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)
Westfalische Wilhelms-Univ. Muenster, Germany.] kindly submitted
by J.Degwert, 26-JAN-1990.
The authors report that their sequence (bp 1-479) is contiguous
with the sequence reported by Y.-H. Chien et al. Please see:
Nature 312, 31-35 (1984), GenBank accession: X01133.
FEATURES Location/Qualifiers
CDS <1..354
/note="T-cell receptor alpha-chain precursor V-J-C region
(AA at 1)"
/codon_start=1
sig_peptide <1..57
/note="T-cell receptor alpha-chain signal peptide"
/codon_start=1
mat_peptide 58..351
/note="T-cell receptor alpha-chain"
/codon_start=58
misc_recomb 339^340
/note="V-region DNA end/J-region DNA start"
BASE COUNT 120 a 141 c 107 g 111 t
ORIGIN Chromosome 14, band C-D.
1 cctggcacct gctcagttct tgtgctcctc ctaatgctca ggaggagcaa tggagatgga
61 gactcagtga cccagacaga aggcctggtc actctcaccg aggggttgcc tgtgatgctg
121 aactgcacct atcagactat ttactcaaat cctttccttt tctggtatgt gcactatctc
181 aatgaatccc ctcggttact cctgaagagc tccacagaca acaagaggac cgagcaccaa
241 gggttccacg ccactctcca taagagcagc agctccttcc atctgcagaa gtcctcagcg
301 cagctgtcag actctgccct gtactactgt gctttgaaag gggagcaata ctagaaaact
361 catctttggg ctggggacaa ctttacaagt gcaaccagac atccagaacc cagaacctgc
421 tgtgtaccag ttaaaagatc ctcggtctca ggacaggacc ctctgcctgt tcaccgact
//