GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS MUSTCBYAL 479 bp ss-mRNA ROD 14-MAR-1991 DEFINITION Mouse T-cell receptor rearranged beta-chain mRNA V-J-C region, 3' end. ACCESSION M31648 KEYWORDS T-cell receptor; T-cell receptor beta-chain; constant region; diversity exon; joining exon; variable region. SOURCE Mouse (strain CBA/J; haplotype H-2k) spleen T-suppressor lymphocyte cell line BVI, cDNA to mRNA, clone BVI/5.beta-11. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 479) AUTHORS Heuer,J., Degwert,J., Pauels,H.-G. and Koelsch,E. TITLE T cell receptor alpha and beta gene expression in a murine antigen-specific t suppressor lymphocyte clone with cytolytic potential-1 JOURNAL J. Immunol. 146, 775-782 (1991) STANDARD simple staff_entry COMMENT Draft entry and computer-readable sequence [Unpublished (1990) Westfalische Wilhelms-Univ. Muenster, Germany.] kindly submitted by J. Degwert, 26-JAN-1990. The authors report that their sequence (bp 1-479) is contiguous with the sequence reported by Y.-H. Chien et al. Please see: Nature 309, 322-326 (1984), GenBank accession: X00069. FEATURES Location/Qualifiers CDS 31..>479 /note="T-cell receptor beta-chain precursor V-J-C region" /codon_start=31 sig_peptide 31..87 /note="T-cell receptor beta-chain signal peptide" /codon_start=31 mat_peptide 88..>479 /note="T-cell receptor beta-chain" /codon_start=88 misc_recomb 369^370 /note="V-region DNA end/D-region DNA start" misc_recomb 388^389 /note="D-region DNA end/J-region DNA start" misc_recomb 435^436 /note="J-region DNA end/C-region DNA start" BASE COUNT 104 a 134 c 119 g 122 t ORIGIN Chromosome 6, band B. 1 cgcggaatcc gcctctgccc tcaatctgcc atgggcacca ggcttcttgg ctgggcagtg 61 ttctgtctcc ttgacacagt actgtctgaa gctggagtca cccagtctcc cagatatgca 121 gtcctacagg aagggcaagc tgtttccttt tggtgtgacc ctatttctgg acatgatacc 181 ctttactggt atcagcagcc cagagaccag gggccccagc ttctagttta ctttcgggat 241 gaggctgtta tagataattc acagttgccc tcggatcgat tttctgctgt gaggcctaaa 301 ggaactaact ccactctcaa gatccagtct gcaaagcagg gcgacacagc cacctatctc 361 tgtgccagca gacccgggac tgggactagt caaaacacct tgtactttgg tgcgggcacc 421 cgactatcgg tgctagagga tctgagaaat gtgactccac ccaaggtctc cttgtttga //