GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS DROD1DE 3387 bp ss-mRNA INV 14-MAR-1991
DEFINITION D.melanogaster insulin-degrading enzyme (d1DE) mRNA, complete cds.
ACCESSION M58465
KEYWORDS insulin-degrading enzyme; metalloproteinase.
SOURCE D.melanogaster, cDNA to mRNA.
ORGANISM Drosophila melanogaster
Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE 1 (bases 1 to 3387)
AUTHORS Kuo,W.-L., Gehm,B.D. and Rosner,M.R.
TITLE Cloning and expression of the complementary DNA for a drosophila
insulin-degrading enzyme
JOURNAL Mol. Endocrinol. 4, 1580-1591 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 298..3270
/product="insulin-degrading enzyme"
/gene="d1DE"
/codon_start=298
BASE COUNT 968 a 804 c 829 g 786 t
ORIGIN Chromosome 3L(77B).
1 cgctatttta gttgttgcga aactagttag aatttatttt tcggtccaaa aagcgattaa
61 aattgattga acgtgtaacc gaccggcttg gaaatctact cctcccactc tgagatttcg
121 tgtgcgcgct acgtaaagcc ggagtagcgt cgtcaagagt atttcacaaa ctcaatgtat
181 cttacgtgca gaaaatcgat ttttgcctta acagcggttt ttggtcgacg gtcaagtgcg
241 ttgagggcca gcatttcagt aacacatcga acgattggca cgcttataaa acccaagatg
301 acaatagccg aaagctcgca aaagtccgta actaggaagc cagacagcat ggagcccata
361 ttgaggctga acaacattga aaagtcgctg caggacacac gcgactaccg cggattgcaa
421 ctagaaaatg gactaaaggt cctgctcatc agcgatccca acacagatgt ctcggcggca
481 gcgctgtccg tgcaagtggg ccacatgtct gatcccacga acctgcctgg attggcccac
541 ttttgcgagc acatgctgtt cctcggcacc gagaagtatc cgcatgagaa tggctacacc
601 acataccttt cgcagagcgg cggaagcagc aacgccgcca cctatcccct gatgaccaag
661 taccactttc acgtggcgcc ggacaagtta gatggagcct tagatcgctt cgcgcagttc
721 ttcatagccc ccttgttcac gcccagtgca actgagcggg aaatcaatgc ggtaaactct
781 gagcacgaga aaaacctgcc cagcgatctg tggcgcatca agcaggtgaa ccgccacctg
841 gcaaagcctg accatgccta cagcaagttc ggcagcggca acaagaccac cctatccgaa
901 atacccaagt ccaagaacat tgatgtgcgg gatgagctgc taaagtttca caagcagtgg
961 tactccgcca acataatgtg cctggctgtc attggaaaag aatcgctgga cgaactggag
1021 ggcatggtat tggagaagtt ctccgaaata gagaacaaaa acgtcaaggt tccaggttgg
1081 ccacgccacc cctacgccga ggagcgctat ggacaaaagg tgaaaatagt gcctatcaaa
1141 gacatccgat cgctgacgat aagctttacc acagacgatt tgacgcagtt ctacaagtca
1201 ggccctgata actatttgac ccacctcatc ggtcacgagg gcaagggcag cattttatcc
1261 gagctgcgac gtctgggctg gtgcaatgat cttatggccg ggcatcagaa cacgcaaaac
1321 ggctttggat tcttcgatat tgtcgtcgac ctgacgcagg agggtttgga gcacgtggat
1381 gacattgtca agatcgtgtt tcagtacttg gaaatgctcc ggaaagaggg acccaagaag
1441 tggatattgg acgagtgtgt gaaactcaac gaaatgagat tccgcttcaa ggaaaaggag
1501 gagtcggaga atttagtcac acatgccgtc tcgtccatga aaatatttcc cctggaggag
1561 gttcttatag ctccatatct aagcaacgaa tggagtccag acctcattaa aggcctattg
1621 gatgagctgg ttccctccaa aagccgaatc gtcatagtaa gccagagttt tgaaccggat
1681 tgcgacctag cggagcccta ctataaaaca aagtacggca ttacgcgcgt ggccaaagat
1741 actgtgcaat cctgggagaa ttgtgaactt aacgagaacc tgaaactggc gctgccaaac
1801 agcttcatac caacaaactt tgatatatcc gatgtaccag ctgatgctcc caaacatccc
1861 acgattattt tggacacccc cattttgagg gtgtggcata agcaggacaa tcagttcaat
1921 aagccaaagg catgcatgac tttcgacatg tccaatccga ttgcttatct ggatcccctg
1981 aactgcaatc tgaaccatat gatggtgatg ctgctgaagg atcagctcaa tgagtacttg
2041 tacgatgcgg agctagccag cttaaagctc agtgtgatgg gaaagtcgtg cggcatcgat
2101 ttcaccattc ggggcttcag tgacaaacag gtggtgctgt tggagaagct gttagatcac
2161 ctttttgact tctccatcga cgagaaacgt tttgacatcc ttaaggagga atacgtacgt
2221 tcactgaaaa actttaaggc tgagcaacca tatcagcatt ccatatacta tttagctctg
2281 ttgttaactg aaaatgcgtg ggccaatatg gagctcttgg acgctatgga acttgtcacg
2341 tacgatagag tgttgaactt cgctaaggag ttcttccagc gcctgcacac agagtgtttt
2401 atttttggca acgtgaccaa gcagcaggcc acggacatcg cggggcgagt taacacccgc
2461 ctggaggcta ccaatgcgtc aaagctaccc attttggcgc ggcaaatgct caagaagcga
2521 gagtataagc tgctcgcagg cgacagctac ttatttgaga aggagaatga gttccacaag
2581 agctcctgcg cacagctcta cttgcagtgc ggcgcacaaa cagatcacac aaacataatg
2641 gtaaacctgg tgtctcaggt gctctccgaa ccttgctacg attgcctgcg cacaaaggaa
2701 caactgggtt acatcgtttt cagtggcgtg cgtaaggtga atggagctaa tggcatacga
2761 ataattgtgc agtcagcaaa gcacccgtcc tatgtggaag atcgtattga aaactttctg
2821 caaacttatc tgcaagttat tgaggacatg ccattggatg agtttgagcg gcacaaggag
2881 gctttggccg tgaagaagct ggaaaaacct aagaccatat tccagcaatt cagccagttc
2941 tatggcgaaa tagccatgca gacgtaccac tttgaaagag aggaggctga ggtagcaata
3001 ctccgtaaga ttagcaaggc cgactttgta gactacttca agaaatttat cgcaaaagat
3061 ggcgaagagc gacgcgttct gtccgtacac attgtatccc agcaaaccga tgaaaatgcc
3121 acgtcagaag cggagcccgt agagatcaca aacatggagc gccacaaacc aatcagcgat
3181 attgtgacct ttaagtcgtg caaggagctt taccccattg ctctgccatt ccttgacatt
3241 aaggcgaagg gagcacgcag caagctttaa actgcaataa ggaaattgag gtctttctta
3301 atagcacatg gttttggtct ctttttgttt taattgctcg aaaaaaaaca ttgttttgta
3361 attcacaaat ataaaagaat ttggatc
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