GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMHCF2 15849 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human heparin cofactor II (HCF2) gene, exons 1 through 5.
ACCESSION M58600 J05309
KEYWORDS heparin cofactor II; serpin.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 15849)
AUTHORS Herzog,R., Lutz,S., Blin,N., Marasa,J.C., Blinder,M.A. and
Tollefsen,D.M.
TITLE Complete nucleotide sequence of the gene for human heparin...
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(1750..1796,6948..7852,11623..11896,13654..13798,
14527..15372)
/product="heparin cofactor II"
/gene="HCF2"
exon 1750..1796
/number=1
/product="heparin cofactor II"
/gene="HCF2"
exon 6948..7852
/number=2
/product="heparin cofactor II"
/gene="HCF2"
exon 11623..11896
/number=3
/product="heparin cofactor II"
/gene="HCF2"
exon 13654..13798
/number=4
/product="heparin cofactor II"
/gene="HCF2"
exon 14527..15372
/number=5
/product="heparin cofactor II"
/gene="HCF2"
BASE COUNT 4477 a 3814 c 3642 g 3916 t
ORIGIN
1 gggctttgca tgtgtgagaa caagacagag aatgagggag gtgggcccca cgaggagtgt
61 gggcacagac agcagcctct gcctgtggtg ccacgctgaa gactcagtat tgtatgtgac
121 agatgaaggc tctaagaaga cagctctgac aaaagctaga gtgcaaaatc agactcagac
181 acaaccaccg gtctgtgtcc tgaacacaat ggacctttac actctggaat ttctcaaacg
241 gagcaatgca cagacacccc catgggcccc ttgcacaccc gcagattctc ctaggagtca
301 cattctctct tcagatagac tctgggtgcc gacactccca aacatgctct tgaggagcag
361 tctctgtgat aagctgatct tccagacaat ccagaatatt cttaaaactt tttagatcat
421 aaaatttaaa acacaaatta aaaaacaaat tatcataagg ccgggcacag tgactcatgc
481 ctgtaatccc agcactttgc aaggctgaag caggaggatc acttgagccc aagagttcaa
541 gaccagccta ggcaacatag tgagaccctg tctctacaaa aaagtcaaaa gttagctaga
601 catggtggtg tgcacctgta ttcccagcta cttgcagggc tgaggtgagg aggattgctt
661 cagctcggga ggttgaggct gcagtgagcc aagatcacgc cactgcactc cagcctgggt
721 aacagagtga gaccctgtct caaaaaacac atagggccag gcgtggtggc tcacgcatgt
781 aatcccagca ctttgggagg ccgagacggg aggatcactt cactccagga gttcaacacc
841 agcctggcca acatagtgaa accccgtctc tactaaaaat acaaaaaatt agttggacat
901 ggtggtgtgc gcctgtaatc tcagccactc aggaggctga ggcaggagaa cgcttgaact
961 tgggagacag aggttgcagt gagctgagat cgcaccactg cactccagca tgggcagcag
1021 cgcgaaactc tgtctcaaaa caaacaaaca aacaaacaaa cacccataaa cacaaaatgt
1081 atcacagcct cagagatccc cacgaatgcc taagtggccc tgaatttggg aggcactgct
1141 cagtaatagt cctatctgtc ccacaacaga caggagtgct gggctgcacc tactggcaac
1201 aaacacagca acccttgact gaagaaaggt ccatgccaca atccccttat tctgtaagcc
1261 actaattttg tcctctctcc tccacctttc actgaggaac gagctcttgg aaggacaggg
1321 acacccgcct agtagctgag ccagccacat cagtcctgga gagcaggtgg agggcagatg
1381 ctgtgatcat cccagaagag aggacacagt tggaggcaga tgcatggtct ctactttcag
1441 ctaccctcaa tgcagcctgg tccccagagg cctgaagagc gccttgttta tgtggtgacc
1501 tcaagagggg ctgctcctgc accaaggcta tgtgtgcatg ctaacacagt aaccgtcata
1561 tactcaaagt gtcagctcta agaactggag atgaggagct gcaagccact ctacagttat
1621 caaaggcaca gctgaggggg tttgtgctga ccaagctggt tgcctggtgt ttggattggg
1681 acttatttac tttggaaaat atgcagcaac agcccagcac caaagttcac atcaaaatcc
1741 cactgatgac cttggctgct ttcatctctg aagcgccact tctcagaaac acagaggtaa
1801 gttgggtttc taatgtttct gctgattata aattattttt ggtgtttacg gataggcaac
1861 tggttcattt ttctagcaaa ctaagaattc agaagctttc tacactgttt tagaagtggg
1921 aaatggtttc atttttcagt gtgcctatta taaaattgtg tcagttccat tgttgggaga
1981 gttgacaaac ttagaatagg agctgtggaa tagatgaaaa tattgtactt atattaaatt
2041 aatcgaattg gataactgtc ctgtgattat gtatgagaat atccttgctc ttgggtattt
2101 tccctgaagt attagtatta aaggttagag gggccgggtg cagtggctca cgcctgtaat
2161 cccaacactt tgggaggccg aggcgggtgg atcacgaggt caggagttca agaccagcct
2221 gaccaacatg gtgaagccaa gtctctacta aaaatacaaa aattagctgg gcgtggtggc
2281 acgcgcctgt aatcccagct actcaggagg ctgaggcagg agaatcgctt aaacccggga
2341 ggcagaggtt gcagtgagcg gagatcgtgc cactgcactc cagcctggac aacagagtta
2401 gactccgtca aaaaaaaaaa aaaaaagaag aaaaaagaaa aaatgttaga ggaacaagat
2461 ataggagacc tactctcaaa tggtctagaa gaaaaaatgt gtatgtgcat gcctgtgaga
2521 acacacacgt acgtacacac acacacagat aatgacaggg caaaggttcc aaaattttaa
2581 acctggtaaa tctcggtacg ggtatacagg agttgttcta ctacactatt ctttcaacat
2641 ttttggaagt ttgaacttac ttcaaaataa aaagttttcc aaactttagg cagttacttc
2701 tctcccattc tgcctgctct gttgggcctg gagaccatac accaggaggg atgacggttt
2761 atcaagtgtt atgctctgat gcgtgactga aaaggccaac ccagctctgg caattagcaa
2821 gaaagcacaa tatgaagttc ccaggaaaaa aaaaaagcaa aacaaacttt tgaatgattt
2881 atctttaaaa tatattgttt ctcttcaaac agtaatctgg atttaatcac aacctagtga
2941 tagtttttaa acgtcttcta caatgtttgt tatactaaat agcaaaacat caggaagatt
3001 taccttcaga tctttaattt caatccataa aagatatcag agatattttc tccttcctct
3061 ggtaagggaa tgacgaaaac tatttttggc tttttatcag ataatgtggg aacagggtat
3121 aagaagtttc caaatataac ttctgaatac cgggataaaa catgcatgtc tttactctgc
3181 cactctatct ggcctcagat acgttttcct gaatgcttat ttattcaagt tggtttttgt
3241 tttgttcttt aaccttattt ttatctgaga agaaaacatt ttcccccttt gttccttctt
3301 cttttggctt tcttttttaa aatagagatg aggtcttgct atgttgctcc agctggtctt
3361 gaactcctgg gctcaagcga tcctcctgcc ttggcctccc aagatgctaa gattacaggt
3421 gtgagcccct atgcctggtc ttcttcttct tgatcttagc caaaaggcca agaagtgata
3481 agaggaggac acttgaagtg tagttgggca aggagccttc taccagctgc ttactttctt
3541 tgttcctgac ttttaaaagt gtgttgctat tgatacacag tctcctgata tgtaaaatgc
3601 tgggaggatg aagctaagtt actcaaagtg ccattcagaa actgggccca gttctatttg
3661 cagctacata cattagaaat catttctaga ggctgagcat ggtaactcat acctgtaatt
3721 ccagcacttt gggaggccaa ggcaggagaa ttgcctgagc tcaggagttt gagacctgtc
3781 tgggcaacat ggtaaaaccc catctttacc aaaaacacaa aaaattaact gggtttggtg
3841 gcacacacct gtggtcccag ctacttcaaa aggctgaggt gggagggtct cttgagcctg
3901 agaggaacag gtggcagtga accaatattg tgccactgca ctccagcctg ggtgacagag
3961 tgagaccccg ccgtctcaaa ataaaaataa aaagaaatcg tttctagaaa ctgttttccc
4021 gtgtgtaaac tagtggcact gcagcctgag gcaggtgctg agatggggac ctggaaaagg
4081 caacaggcat tttgagtcag aaacaatgtg actttcctgc tccaaaatgt gcaattcaaa
4141 agtctttctt agttgtgact aaaacaaact ttgaacttac tatttcaaca gtattataag
4201 gggaagaccc aaggaatggg actggcactg ggaaaacagc taggaagctg ctctgcacgg
4261 ccagggagtc tggaagcatc ctggtactcc agagcgaaca aggctgagcg cttgatgtgg
4321 ggcttagagg cttaaccaac ttggttcgaa tctagccact gccacttatt agtgacagtg
4381 acgaaaggct cagtctcctg atatataaaa tgttgggagg atgaaactaa gttacacgaa
4441 gtgccttata cagcgtgtca ggcatccaac agaggccatt atcaacatta accacactga
4501 cagcatttca agcagagtat ccgaacagtt accccatctt caggcctact gagttcaaat
4561 atttgcttaa caagagcagc cagtaactct tacctggcct caactggcag cagatattct
4621 gggcctcaaa tatctatcta ataggaaatg gtcacagaca caaaataagc ttaacaaaag
4681 gcagtttttt tttgtttttt ttttgttttc tgttttttga gataaggact cactctatcc
4741 cccaggttgg agtgcagtag tggcgtgatc acggctcact gcagactcaa gtgatcctcc
4801 tacttcagcc tctcaagtag atgggaccac aggcgtgtgc catcacacca ggctaattat
4861 ttttcttttc tttttttttt ttttgagacg gagtttcgct ctttttgccc aggctggagt
4921 gcaatggtgc gatcttggct caccacaacc tctgcctcct gaattcaaac gaatctcctg
4981 cctcagcctc ctaagtatct gggattacag gcatgcgcca ccacgccggc taattttttt
5041 gtattttttg tagagacagg gtttctccat gttggccagg ctggtctcga actcccgacc
5101 tcagatgatc cgcccacctc ggcctcccaa agtgctggga ttactgacct gagccaccgc
5161 acccagccta tttatttaat ttttcacaga gatgaggtct tgctatgttg cccacactgg
5221 tcttgagctc ctgggctcaa gtgatcttcc tgccttggtc tcccagtgtt gggattatag
5281 gcgtaagcca cagcgcctgg ccggcagttc tttctggggt gattagaagt tgggaccatg
5341 tattacctgt ctgagtcagc attataaaca cctatggtca ctgtcctggc aaaacatgga
5401 atcatcaaag ctcatctaac cagagtgcag ttaataacca ggaagtaagc aagagaaaga
5461 caaaggattt ggcagtcaaa acagatttga caggccaagt cagatcctcc tctgaacgag
5521 tcagaggaac aaataaagac aggattgcca taatgcctct gtgctaaaag cttatcttgt
5581 ttacttaaat aaagggagtg cccctcaggt cttgagtaag agcttgctga catcaccctc
5641 acacagactt tatctcttgt ttctaaccct gtgttagaag cagtaacaca gaagatttag
5701 ttgctcctga cagcagtggg agctattgtc taagagatac aaaggagaaa aaagtatacc
5761 tgcagcaagt gatatcacct ctggggctgc caccacatca cctcactacg ccctgagggg
5821 gtctcagcac tagacaagtt ccaaatcttt tgcaaattaa acaaccccag gtcaggcgtg
5881 gtggcttatg cctgtaatcc cagcactttg gggggctgag gtgggtggat cacctgaggt
5941 caggagtttg agaccagcct ggccaacaga gcaaaacccc atctctacta aacaaaatac
6001 aaaaattaac caggcgtagt ggtgtgcacc tgtagtccca gctacttggg aggctgaggc
6061 aagagaattg cttgagtcca ggaggccgaa gttgcagtaa gccgagatcg cgccactgca
6121 ctccagcctg ggtgacagag tgagactcca tttcaaaaaa taaaaacaac aaaagccaat
6181 tacaacaaca acaacaaaaa aacaacgaat taaacaaccc caaagattgc acaaatttca
6241 agtatcttta gaatatgttt tcagaaagcc tggcccatgg acatttttca acagcatctc
6301 cattgcaaag gtggaatggt gtgagtcaca caggcatggc tgagtcccac taatgcacat
6361 cccttctagg tactctccaa tcaccagccc caggtgccca ctcaagccca gctcttagtg
6421 aggtttccct gactctctgg gcacttccac tcctaccaca cagggtagag ccacacccct
6481 ttccgtaccc ccatgtgctc tggcagcatt attttgagag ccttcgcttt actgcacgtc
6541 tgtcccatct gtcccctgac tggtccatga gcccctggtg ggaactttgt ctctggtaac
6601 taaacactgt ctggaggtgg tggacaaggt gtctggagaa aaacaaactc ctccctggga
6661 tgcctgagct cccaggattc tagaaggtta gttttgcaaa cctttaaaga agggattttc
6721 atcaaggggc ccacagatcc ttcattgagg tttatgagtc ccacatcaaa ggttgggtgt
6781 ctatctacat cagattctct taaagtccat gatcctaaaa cagttaagaa ctaatgctgt
6841 gagggcctct tcctgggtca aagccacagg gaacctgcca tgtggatgct gcagcggggt
6901 gtggatcagc caggccgcct ttcactgtgt tctgttttcc ctcccagctt tagctccgcc
6961 aaaatgaaac actcattaaa cgcacttctc attttcctca tcataacatc tgcgtggggt
7021 gggagcaaag gcccgctgga tcagctagag aaaggagggg aaactgctca gtctgcagat
7081 ccccagtggg agcagttaaa taacaaaaac ctgagcatgc ctcttctccc tgccgacttc
7141 cacaaggaaa acaccgtcac caacgactgg attccagagg gggaggagga cgacgactat
7201 ctggacctgg agaagatatt cagtgaagac gacgactaca tcgacatcgt cgacagtctg
7261 tcagtttccc cgacagactc tgatgtgagt gctgggaaca tcctccagct ttttcatggc
7321 aagagccgga tccagcgtct taacatcctc aacgccaagt tcgctttcaa cctctaccga
7381 gtgctgaaag accaggtcaa cactttcgat aacatcttca tagcacccgt tggcatttct
7441 actgcgatgg gtatgatttc cttaggtctg aagggagaga cccatgaaca agtgcactcg
7501 attttgcatt ttaaagactt tgttaatgcc agcagcaagt atgaaatcac gaccattcat
7561 aatctcttcc gtaagctgac tcatcgcctc ttcaggagga attttgggta cacactgcgg
7621 tcagtcaatg acctttatat ccagaagcag tttccaatcc tgcttgactt caaaactaaa
7681 gtaagagagt attactttgc tgaggcccag atagctgact tctcagaccc tgccttcata
7741 tcaaaaacca acaaccacat catgaagctc accaagggcc tcataaaaga tgctctggag
7801 aatatagacc ctgctaccca gatgatgatt ctcaactgca tctacttcaa aggtaagagg
7861 cacctttaca gttctcacag caaacccaca acatactatt tttgtatgtg ggtagattga
7921 atgccaagaa ctgtactgta gctataattt atccaggaaa actagacaca agattgactc
7981 tggaacgggg acagggaagg ccaagctgaa gtgacagtag catctgacac ttactgagcc
8041 ctaactctgt gctttaacac agccttgtga ggtcatcact gttattagca tccccatttt
8101 acagaggaag ccaccaacac atgaagtaaa aggatgggct gggcgcggtg gctcacgcct
8161 gtaatcccag cactttggga ggccgaggca ggcagatcac ttgaggtcag gagttcgaga
8221 tcagcctgac caacagacca acatggtgaa aacctggctc tactaaaaat acaaaaatta
8281 gctgggcctg gcggtgggtg cctgtactcc cagctacttg ggaggctgag gcaggagaat
8341 cacttgaacc tggaaggcag agattgcagt gagccgagac tgtgccactg cactctagcc
8401 tggacgacag agtgagactc catctcaaaa aaaaaaaaaa aagaagtaaa acgatgctcc
8461 aagggcaccc agttattaag gggcagagcc aaagctgaac ccagggaggc caaccctagc
8521 aatctgttaa attggaagaa ataatacaaa aactgtttta gcatttggcc agcctggatt
8581 tgagttttct cttttccttt cccaattatc aataagcagg aatatagaca aaaggctaaa
8641 gaaatgcacc tgtgaactat tcagcttgag cagctgacat tgacacctac aagtgctttt
8701 caggatactt ttgaactact gggcaggtgg gatggagaaa taaattacta tttccccagc
8761 aactgttctg ggctgagcac aagggcactt tttaaggagg tcaccccaca cccatcacac
8821 acacatagga cccctggaat cctaggaata aataagcatg gatttgtaaa atccaaacct
8881 ctcttttcaa atatcctcac ctggaccaga ccagaagaaa cctctacttt actctctaag
8941 ctgagagtgt ggaaggggaa acacgaggaa tggttcggct tcaggactaa ttgcggtgac
9001 acacaaccac ttctctttgc caccaaggac taccaggtac ctgcaaaggg cagtacttgg
9061 aggccagtgc tttctgctag ttagctcccg tggttttata gcagcccagg cgaaggaagg
9121 agaccccccc cagctcctgg cttctgttca gggaaagggg gccagagccc ctcctgatct
9181 gtccacacac ctgctctgtg ccttggctga ggcccctgca gctctacaag gcaggcattc
9241 tgctggatag gccaagcagg gtcactctga cacccaggtt tccaccccaa ggcatggcac
9301 aatgctggcc tcctgtgggt ggaatcaaag gctgagttct aacaggcttg cggcagacac
9361 acacacagag accacatgta catgatgaac acacatatcc ttttcattac aggttattag
9421 tacaagtttt ggaattgagc aaacaagagt ctaagcgctg gtttcaccac ttctcgtttg
9481 tgtgacctca gacaagtcat tcaacatctc tatgactcag tttccttatc tttatcacag
9541 agatgacacc cactctgaca gggccgaggg aagaaccata agcgatggca atgcaacaga
9601 gtggcacatg acaagagctc agcgaatttg agggaatgaa actgtagatt acaatactag
9661 tacaatatga taaacatatg atattgttag tgacatttat tttacttcta ctagcaaata
9721 acctatgttt aggactgact ttagaacagg ctggcagaag catttttggc agcatcaaag
9781 tcctccaacc tactggtctg ttggagcccc ccaagtacac caaagagcct ctgcattagc
9841 cctggctgag ggttcaggga caggcagaga agtacagcag tgagccatcc ctgcctgcat
9901 ggaggtggag aaatgatcag gcatggtcag ttgacaatct cctaaacaca gtaacccgtg
9961 tcataccaca gtgtaaacac acgtgcaaat gcttctgctt cctttcccca tcatgagaat
10021 agtcactcaa tgccgggcat cacaagggat caaatgctag gagtacccaa tcattcatgg
10081 atgcttctca aaggggacga gtgtctagaa gtgtaatttt aatttcactt aatttcatat
10141 ggaatcatct ccattactaa ttttgttcta attttaatgt gataatcact ttgtaaagca
10201 caataaacag aggcaggctc tcatgaggaa gtcagaagga aagaatccca agagacatgg
10261 gacagctcca tccaaactga aagggccgtg attcccaaaa gagcaatttt gtccccaagg
10321 tctgaagaca cttttggttg tcacaacctg gggggttgga gtaagcatta ctggtatcta
10381 gaagggggag gctggggatg ttgctaaaca ccctaccatg cacagggcag cccacattgc
10441 cacaaactat tatgtggccc aaatgtcaaa aatgctgagg ttgagaaacc ctgggtgagg
10501 cagactcagg gagaagggaa tcgagcttca ctcacaggca ggcaggagct gtctggtact
10561 tcaacctcca agacacctcc tgctcatctc atcctggctg ctctacccac cagctagaaa
10621 ccttgaacaa gttacttcac ttctttgtgc ctctgtttcc tcatatgtaa aagagggata
10681 acaaaacgca cacaacttgc atgttgctag gagcagaaat gagataatac aggaaaggtg
10741 ctgagaagaa tgcccggcac atggccagtt ctcaactact agtcacccat tactattagt
10801 tactcacatc ttagagctaa catagacatg ggcttattcc tggatacaca gcactgtccc
10861 catatctaca gtggtgatcc taagggcaac atggcatcac ccaaatgtct tgttagtcac
10921 tacagaatca cagtgtgagg gatgaaggcc atcaagacag agctgaggct ggcagggtgg
10981 ctcatgccta taatcccagt gctttggaag gctgaggcag gaggattgct tgaggccaag
11041 ggtttgagac cagcctaggt aacatagcaa gaccccatct acaattaaaa aaaaaaaaaa
11101 aaagacagaa agaaaaaata gccaggcgtg gcatgtgctt gtagtccaag ctactgggga
11161 gggaggctga ggcaggagga ttccttgagc ctgggagtgt gaggctgcag tgagctatga
11221 tggcatcgcc gcactccagc ctgcatgaca cagtgagacc tggtctcaaa aaccaaataa
11281 taataacagt aataaaagct ggaaagagct caaagttact catttgacag atgtgacaga
11341 tgaagaaata gaagcgagtt aggtgcctta ccatggtcaa acaactagtt cgtatcagac
11401 cctactccag aaactattcc agtccgggta acctctcgtt aacctctctt gttagaaatg
11461 caaatttctg cccaaatcag gcctcaggaa tcaagagact gtggggtcgg ctctgcaggc
11521 tatctgaatg aggcctccag ggaaatcaga ttcactctca agggtgagac gatttcccta
11581 aaggaacctt ctcataacag cctcttcctg tggcctttac aggatcctgg gtgaataaat
11641 tcccagtgga aatgacacac aaccacaact tccggctgaa tgagagagag gtagttaagg
11701 tttccatgat gcagaccaag gggaacttcc tcgcagcaaa tgaccaggag ctggactgcg
11761 acatcctcca gctggaatac gtggggggca tcagcatgct aattgtggtc ccacacaaga
11821 tgtctgggat gaagaccctc gaagcgcaac tgacaccccg ggtggtggag agatggcaaa
11881 aaagcatgac aaacaggtat ttcacactgt gtgtttgttc ttttgagctc ccagatgctg
11941 ggggtgtctg ggaatactgg aaaatggatc atttttttaa aaagggagaa ttatgtacaa
12001 gtacccaaga acttccatac agggccactc tgttaattca gccccaattt gttgcttgag
12061 ataagagatg attagagagc attcataagg gacacatctg ccctctaggg gccagtttca
12121 gaagttagag gcagatgact tagagacagc ttggtgcttg ctttgtggct tcgagtccca
12181 gcttcatcat ccctaaaatg ggtataattc cattacttcc ccgggtcact tgagaaaata
12241 acagaatcag cgatgctgag cgcccctccc agtacttgga acctaggagg cactcaaaaa
12301 aagattggct caactcttcc ctgcccagga aattccaagg tcctcttagc ctaccgagga
12361 cacatcattc atgatttcct ctattattat tcgttacttt gtagttaaaa ctgcaggtgt
12421 taagtactta ttgagattat tattgggtca tggcagaaag aatggagagg tcttatttct
12481 gtcttactgg atactggcta ggcccatatg aagaagtgat tctggtttga acctccttat
12541 aggacaagaa tacaaacata tgcaaccaaa ctgagaaaag taggctctca gaggaaggta
12601 tttgcccggg tagccagtca tcatgctctg tgaatttttc cttaacaacg tcccttctgt
12661 acctgcctcc ttccattcct ccctgcagcc cggcagctct tgagaaaggg actgcatctt
12721 tttttttttt ttttttttga gacagggtct tgttctgtca cccaggctgg agtgcagtgg
12781 catcatcatg gctcactgca gcctcaacct cctgaactta agtgatcctc tcacctcagc
12841 ctcctgaata gttgagacta caggcgtgca ccttcatgcc cagctaatta aacttttttt
12901 ggtagagatg aggtctcgct gtgttgccca ggctggtctt gaactcctgg cctcaagcag
12961 tcctcctgcc ttggccttcc aaagtgctgg gattaacagg cgtgagccgc tgtgcctggc
13021 ccatttgact tttaattgag atcttacttg gtgcaaggta tgagctaggt aaaagagtga
13081 agaagatcaa gccttcctgc ccatccagct gggattgcac cttaaatctc tttatcccct
13141 gcaaagtgcc agactaactc cacaggcact actgttgcta tccgccccct tagggattga
13201 gtaagttgag gcaaagattg agatattcag cattgtctag tatatacagg aaaggttctt
13261 tttaaaagta cactaccaga tattcgactc cttaattaca aaaaaaaaac caaatgccta
13321 aaattgggaa accaaaccag agaattattt tagatgcctt tttaaaccat aaaccaggaa
13381 aagttctgct gctaaccttg aagataggaa acgaaccata cagtctcaag gaaataatca
13441 tgcaacagaa aacacacctc agttttcagt agcggaatta caaaggagtg tgcttcctaa
13501 aatcctcaac tgacagtccc ggaatataaa ttttaataag tgctatatca attctgtgat
13561 aaatataacc cgtggccctt taaagggaaa atcatgattc ttttgtaact tgtggttcaa
13621 taaaactggg cccccctttc cttttctgtc tagaactcga gaagtgcttc tgccgaaatt
13681 caagctggag aagaactaca atctagtgga gtccctgaag ttgatgggga tcaggatgct
13741 gtttgacaaa aatggcaaca tggcaggcat ctcagaccaa aggatcgcca tcgacctggt
13801 aaccactccc ttgtccaccc ccgacccgtc cccagggtct gcctcagcac agccccacct
13861 ccacttgccc ttcctaccca ccccccaatc tcatgtccca gcttggggtg ctgagtctgc
13921 tcttcggcct gggtgggata cacagaatgc ctagtttcat ggatgccagc tggagagcac
13981 ggcacctggc agacacttac tgggcagggg ggatcccaag agcagccatg gggtgagccc
14041 cactcccgct gacaccagag acaggggaga catgtgctgc ggtctgggaa atagctaccc
14101 ccagccaaat catgaaagag ccattaaaca ccgcactata caacatactt aacttaaacc
14161 aatcgggtcg ctcagcaaaa gagagagaac accagtccaa acagtgcagc agacccagtt
14221 ccccatcccg gagaagtgcg cagcagtgtg gggagctgga gctggggtgg ctgtcctgca
14281 ccagccccca cgaccctcag accacaggca ctgccaagag ggaacatgaa cctagccggc
14341 ctctaagtgc aacggctgcc cctgacaggt ggtgacagat attttcaaga gtgactctga
14401 ccagctgtga tttccacctt acatgttgtc tttggatcct ttccctgaat gatatgagat
14461 tgtgctggga actctagccc tctgtgtgct gacctccaga atctgacaac tttcctttcc
14521 aaacagttca agcaccaagg cacgatcaca gtgaacgagg aaggcaccca agccaccact
14581 gtgaccacgg tggggttcat gccgctgtcc acccaagtcc gcttcactgt cgaccgcccc
14641 tttcttttcc tcatctacga gcatcgcacc agctgcctgc tcttcatggg aagagtggcc
14701 aaccccagca ggtcctagag gtggaggtct aggtgtctga agtgccttgg gggcaccctc
14761 attttgtttc cattccaaca acgagaacag agatgttctg gcatcattta cgtagtttac
14821 gctaccaatc tgaattcgag gcccatatga gaggagctta gaaacgacca agaagagagg
14881 cttgttggaa tcaattctgc acaatagccc atgctgtaag ctcatagaag tcactgtaac
14941 tgtagtgtgt ctgctgttac ctagagggtc tcacctcccc actcttcaca gcaaacctga
15001 gcagcgcgtc ctaagcacct cccgctccgg tgaccccatc cttgcacacc tgactctgtc
15061 actcaagcct ttctccacca ggcccctcat ctgaatacca agcacagaaa tgagtggtgt
15121 gactaattcc ttacctctcc caaggagggt acacaactag caccattctt gatgtccagg
15181 gaagaagcca cctcaagaca tatgaggggt gccctgggct aatgttaggg cttaattttc
15241 tcaaagcctg acctttcaaa tccatgatga atgccatcag tccctcctgc tgttgcctcc
15301 ctgtgacctg gaggacagtg tgtgccatgt ctcccatact agagataaat aaatgtagcc
15361 acatttactg tgtatctgtt ataattctct attttttgaa gctcaaatat caaaagccaa
15421 atccaaattc ctggataact ccaggtatga taaaggctga gaggaagtca cttgagcacc
15481 acaatgtgcc acagcagggc atgttctcag gacaggacag gtgtgtgctg aatcctgggg
15541 agggtctgtg cagtacccca gaactgtggg gtgctaagtg gcacacaagc cccagggctc
15601 ccacagtcta tgccaggctg ctgcagcttt catccctcat acctggtcct gcagtgggtc
15661 tggtttgaca gagcagatga cacctgagga atatgtttct ggatccttca atccctgggt
15721 aagacaagtg aaatccacag aggctgttca gcacgcaaga gtgccagtgc tctttcagtg
15781 aggggatgac tgacggtcac aggtgctgtg tgtgcaggtg tctaactgta accccacagc
15841 ctggcagat
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMHCF2 15849 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human heparin cofactor II (HCF2) gene, exons 1 through 5.
ACCESSION M58600 J05309
KEYWORDS heparin cofactor II; serpin.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 15849)
AUTHORS Herzog,R., Lutz,S., Blin,N., Marasa,J.C., Blinder,M.A. and
Tollefsen,D.M.
TITLE Complete nucleotide sequence of the gene for human heparin cofactor
II and mapping to chromosomal band 22q11
JOURNAL Biochemistry 30, 1350-1357 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(1750..1796,6948..7852,11623..11896,13654..13798,
14527..15372)
/product="heparin cofactor II"
/gene="HCF2"
CDS join(6964..7852,11623..11896,13654..13798,14527..14718)
/product="heparin cofactor II"
/gene="HCF2"
/codon_start=6964
exon 1750..1796
/number=1
/product="heparin cofactor II"
/gene="HCF2"
exon 6948..7852
/number=2
/product="heparin cofactor II"
/gene="HCF2"
exon 11623..11896
/number=3
/product="heparin cofactor II"
/gene="HCF2"
exon 13654..13798
/number=4
/product="heparin cofactor II"
/gene="HCF2"
exon 14527..15372
/number=5
/product="heparin cofactor II"
/gene="HCF2"
BASE COUNT 4477 a 3814 c 3642 g 3916 t
ORIGIN
1 gggctttgca tgtgtgagaa caagacagag aatgagggag gtgggcccca cgaggagtgt
61 gggcacagac agcagcctct gcctgtggtg ccacgctgaa gactcagtat tgtatgtgac
121 agatgaaggc tctaagaaga cagctctgac aaaagctaga gtgcaaaatc agactcagac
181 acaaccaccg gtctgtgtcc tgaacacaat ggacctttac actctggaat ttctcaaacg
241 gagcaatgca cagacacccc catgggcccc ttgcacaccc gcagattctc ctaggagtca
301 cattctctct tcagatagac tctgggtgcc gacactccca aacatgctct tgaggagcag
361 tctctgtgat aagctgatct tccagacaat ccagaatatt cttaaaactt tttagatcat
421 aaaatttaaa acacaaatta aaaaacaaat tatcataagg ccgggcacag tgactcatgc
481 ctgtaatccc agcactttgc aaggctgaag caggaggatc acttgagccc aagagttcaa
541 gaccagccta ggcaacatag tgagaccctg tctctacaaa aaagtcaaaa gttagctaga
601 catggtggtg tgcacctgta ttcccagcta cttgcagggc tgaggtgagg aggattgctt
661 cagctcggga ggttgaggct gcagtgagcc aagatcacgc cactgcactc cagcctgggt
721 aacagagtga gaccctgtct caaaaaacac atagggccag gcgtggtggc tcacgcatgt
781 aatcccagca ctttgggagg ccgagacggg aggatcactt cactccagga gttcaacacc
841 agcctggcca acatagtgaa accccgtctc tactaaaaat acaaaaaatt agttggacat
901 ggtggtgtgc gcctgtaatc tcagccactc aggaggctga ggcaggagaa cgcttgaact
961 tgggagacag aggttgcagt gagctgagat cgcaccactg cactccagca tgggcagcag
1021 cgcgaaactc tgtctcaaaa caaacaaaca aacaaacaaa cacccataaa cacaaaatgt
1081 atcacagcct cagagatccc cacgaatgcc taagtggccc tgaatttggg aggcactgct
1141 cagtaatagt cctatctgtc ccacaacaga caggagtgct gggctgcacc tactggcaac
1201 aaacacagca acccttgact gaagaaaggt ccatgccaca atccccttat tctgtaagcc
1261 actaattttg tcctctctcc tccacctttc actgaggaac gagctcttgg aaggacaggg
1321 acacccgcct agtagctgag ccagccacat cagtcctgga gagcaggtgg agggcagatg
1381 ctgtgatcat cccagaagag aggacacagt tggaggcaga tgcatggtct ctactttcag
1441 ctaccctcaa tgcagcctgg tccccagagg cctgaagagc gccttgttta tgtggtgacc
1501 tcaagagggg ctgctcctgc accaaggcta tgtgtgcatg ctaacacagt aaccgtcata
1561 tactcaaagt gtcagctcta agaactggag atgaggagct gcaagccact ctacagttat
1621 caaaggcaca gctgaggggg tttgtgctga ccaagctggt tgcctggtgt ttggattggg
1681 acttatttac tttggaaaat atgcagcaac agcccagcac caaagttcac atcaaaatcc
1741 cactgatgac cttggctgct ttcatctctg aagcgccact tctcagaaac acagaggtaa
1801 gttgggtttc taatgtttct gctgattata aattattttt ggtgtttacg gataggcaac
1861 tggttcattt ttctagcaaa ctaagaattc agaagctttc tacactgttt tagaagtggg
1921 aaatggtttc atttttcagt gtgcctatta taaaattgtg tcagttccat tgttgggaga
1981 gttgacaaac ttagaatagg agctgtggaa tagatgaaaa tattgtactt atattaaatt
2041 aatcgaattg gataactgtc ctgtgattat gtatgagaat atccttgctc ttgggtattt
2101 tccctgaagt attagtatta aaggttagag gggccgggtg cagtggctca cgcctgtaat
2161 cccaacactt tgggaggccg aggcgggtgg atcacgaggt caggagttca agaccagcct
2221 gaccaacatg gtgaagccaa gtctctacta aaaatacaaa aattagctgg gcgtggtggc
2281 acgcgcctgt aatcccagct actcaggagg ctgaggcagg agaatcgctt aaacccggga
2341 ggcagaggtt gcagtgagcg gagatcgtgc cactgcactc cagcctggac aacagagtta
2401 gactccgtca aaaaaaaaaa aaaaaagaag aaaaaagaaa aaatgttaga ggaacaagat
2461 ataggagacc tactctcaaa tggtctagaa gaaaaaatgt gtatgtgcat gcctgtgaga
2521 acacacacgt acgtacacac acacacagat aatgacaggg caaaggttcc aaaattttaa
2581 acctggtaaa tctcggtacg ggtatacagg agttgttcta ctacactatt ctttcaacat
2641 ttttggaagt ttgaacttac ttcaaaataa aaagttttcc aaactttagg cagttacttc
2701 tctcccattc tgcctgctct gttgggcctg gagaccatac accaggaggg atgacggttt
2761 atcaagtgtt atgctctgat gcgtgactga aaaggccaac ccagctctgg caattagcaa
2821 gaaagcacaa tatgaagttc ccaggaaaaa aaaaaagcaa aacaaacttt tgaatgattt
2881 atctttaaaa tatattgttt ctcttcaaac agtaatctgg atttaatcac aacctagtga
2941 tagtttttaa acgtcttcta caatgtttgt tatactaaat agcaaaacat caggaagatt
3001 taccttcaga tctttaattt caatccataa aagatatcag agatattttc tccttcctct
3061 ggtaagggaa tgacgaaaac tatttttggc tttttatcag ataatgtggg aacagggtat
3121 aagaagtttc caaatataac ttctgaatac cgggataaaa catgcatgtc tttactctgc
3181 cactctatct ggcctcagat acgttttcct gaatgcttat ttattcaagt tggtttttgt
3241 tttgttcttt aaccttattt ttatctgaga agaaaacatt ttcccccttt gttccttctt
3301 cttttggctt tcttttttaa aatagagatg aggtcttgct atgttgctcc agctggtctt
3361 gaactcctgg gctcaagcga tcctcctgcc ttggcctccc aagatgctaa gattacaggt
3421 gtgagcccct atgcctggtc ttcttcttct tgatcttagc caaaaggcca agaagtgata
3481 agaggaggac acttgaagtg tagttgggca aggagccttc taccagctgc ttactttctt
3541 tgttcctgac ttttaaaagt gtgttgctat tgatacacag tctcctgata tgtaaaatgc
3601 tgggaggatg aagctaagtt actcaaagtg ccattcagaa actgggccca gttctatttg
3661 cagctacata cattagaaat catttctaga ggctgagcat ggtaactcat acctgtaatt
3721 ccagcacttt gggaggccaa ggcaggagaa ttgcctgagc tcaggagttt gagacctgtc
3781 tgggcaacat ggtaaaaccc catctttacc aaaaacacaa aaaattaact gggtttggtg
3841 gcacacacct gtggtcccag ctacttcaaa aggctgaggt gggagggtct cttgagcctg
3901 agaggaacag gtggcagtga accaatattg tgccactgca ctccagcctg ggtgacagag
3961 tgagaccccg ccgtctcaaa ataaaaataa aaagaaatcg tttctagaaa ctgttttccc
4021 gtgtgtaaac tagtggcact gcagcctgag gcaggtgctg agatggggac ctggaaaagg
4081 caacaggcat tttgagtcag aaacaatgtg actttcctgc tccaaaatgt gcaattcaaa
4141 agtctttctt agttgtgact aaaacaaact ttgaacttac tatttcaaca gtattataag
4201 gggaagaccc aaggaatggg actggcactg ggaaaacagc taggaagctg ctctgcacgg
4261 ccagggagtc tggaagcatc ctggtactcc agagcgaaca aggctgagcg cttgatgtgg
4321 ggcttagagg cttaaccaac ttggttcgaa tctagccact gccacttatt agtgacagtg
4381 acgaaaggct cagtctcctg atatataaaa tgttgggagg atgaaactaa gttacacgaa
4441 gtgccttata cagcgtgtca ggcatccaac agaggccatt atcaacatta accacactga
4501 cagcatttca agcagagtat ccgaacagtt accccatctt caggcctact gagttcaaat
4561 atttgcttaa caagagcagc cagtaactct tacctggcct caactggcag cagatattct
4621 gggcctcaaa tatctatcta ataggaaatg gtcacagaca caaaataagc ttaacaaaag
4681 gcagtttttt tttgtttttt ttttgttttc tgttttttga gataaggact cactctatcc
4741 cccaggttgg agtgcagtag tggcgtgatc acggctcact gcagactcaa gtgatcctcc
4801 tacttcagcc tctcaagtag atgggaccac aggcgtgtgc catcacacca ggctaattat
4861 ttttcttttc tttttttttt ttttgagacg gagtttcgct ctttttgccc aggctggagt
4921 gcaatggtgc gatcttggct caccacaacc tctgcctcct gaattcaaac gaatctcctg
4981 cctcagcctc ctaagtatct gggattacag gcatgcgcca ccacgccggc taattttttt
5041 gtattttttg tagagacagg gtttctccat gttggccagg ctggtctcga actcccgacc
5101 tcagatgatc cgcccacctc ggcctcccaa agtgctggga ttactgacct gagccaccgc
5161 acccagccta tttatttaat ttttcacaga gatgaggtct tgctatgttg cccacactgg
5221 tcttgagctc ctgggctcaa gtgatcttcc tgccttggtc tcccagtgtt gggattatag
5281 gcgtaagcca cagcgcctgg ccggcagttc tttctggggt gattagaagt tgggaccatg
5341 tattacctgt ctgagtcagc attataaaca cctatggtca ctgtcctggc aaaacatgga
5401 atcatcaaag ctcatctaac cagagtgcag ttaataacca ggaagtaagc aagagaaaga
5461 caaaggattt ggcagtcaaa acagatttga caggccaagt cagatcctcc tctgaacgag
5521 tcagaggaac aaataaagac aggattgcca taatgcctct gtgctaaaag cttatcttgt
5581 ttacttaaat aaagggagtg cccctcaggt cttgagtaag agcttgctga catcaccctc
5641 acacagactt tatctcttgt ttctaaccct gtgttagaag cagtaacaca gaagatttag
5701 ttgctcctga cagcagtggg agctattgtc taagagatac aaaggagaaa aaagtatacc
5761 tgcagcaagt gatatcacct ctggggctgc caccacatca cctcactacg ccctgagggg
5821 gtctcagcac tagacaagtt ccaaatcttt tgcaaattaa acaaccccag gtcaggcgtg
5881 gtggcttatg cctgtaatcc cagcactttg gggggctgag gtgggtggat cacctgaggt
5941 caggagtttg agaccagcct ggccaacaga gcaaaacccc atctctacta aacaaaatac
6001 aaaaattaac caggcgtagt ggtgtgcacc tgtagtccca gctacttggg aggctgaggc
6061 aagagaattg cttgagtcca ggaggccgaa gttgcagtaa gccgagatcg cgccactgca
6121 ctccagcctg ggtgacagag tgagactcca tttcaaaaaa taaaaacaac aaaagccaat
6181 tacaacaaca acaacaaaaa aacaacgaat taaacaaccc caaagattgc acaaatttca
6241 agtatcttta gaatatgttt tcagaaagcc tggcccatgg acatttttca acagcatctc
6301 cattgcaaag gtggaatggt gtgagtcaca caggcatggc tgagtcccac taatgcacat
6361 cccttctagg tactctccaa tcaccagccc caggtgccca ctcaagccca gctcttagtg
6421 aggtttccct gactctctgg gcacttccac tcctaccaca cagggtagag ccacacccct
6481 ttccgtaccc ccatgtgctc tggcagcatt attttgagag ccttcgcttt actgcacgtc
6541 tgtcccatct gtcccctgac tggtccatga gcccctggtg ggaactttgt ctctggtaac
6601 taaacactgt ctggaggtgg tggacaaggt gtctggagaa aaacaaactc ctccctggga
6661 tgcctgagct cccaggattc tagaaggtta gttttgcaaa cctttaaaga agggattttc
6721 atcaaggggc ccacagatcc ttcattgagg tttatgagtc ccacatcaaa ggttgggtgt
6781 ctatctacat cagattctct taaagtccat gatcctaaaa cagttaagaa ctaatgctgt
6841 gagggcctct tcctgggtca aagccacagg gaacctgcca tgtggatgct gcagcggggt
6901 gtggatcagc caggccgcct ttcactgtgt tctgttttcc ctcccagctt tagctccgcc
6961 aaaatgaaac actcattaaa cgcacttctc attttcctca tcataacatc tgcgtggggt
7021 gggagcaaag gcccgctgga tcagctagag aaaggagggg aaactgctca gtctgcagat
7081 ccccagtggg agcagttaaa taacaaaaac ctgagcatgc ctcttctccc tgccgacttc
7141 cacaaggaaa acaccgtcac caacgactgg attccagagg gggaggagga cgacgactat
7201 ctggacctgg agaagatatt cagtgaagac gacgactaca tcgacatcgt cgacagtctg
7261 tcagtttccc cgacagactc tgatgtgagt gctgggaaca tcctccagct ttttcatggc
7321 aagagccgga tccagcgtct taacatcctc aacgccaagt tcgctttcaa cctctaccga
7381 gtgctgaaag accaggtcaa cactttcgat aacatcttca tagcacccgt tggcatttct
7441 actgcgatgg gtatgatttc cttaggtctg aagggagaga cccatgaaca agtgcactcg
7501 attttgcatt ttaaagactt tgttaatgcc agcagcaagt atgaaatcac gaccattcat
7561 aatctcttcc gtaagctgac tcatcgcctc ttcaggagga attttgggta cacactgcgg
7621 tcagtcaatg acctttatat ccagaagcag tttccaatcc tgcttgactt caaaactaaa
7681 gtaagagagt attactttgc tgaggcccag atagctgact tctcagaccc tgccttcata
7741 tcaaaaacca acaaccacat catgaagctc accaagggcc tcataaaaga tgctctggag
7801 aatatagacc ctgctaccca gatgatgatt ctcaactgca tctacttcaa aggtaagagg
7861 cacctttaca gttctcacag caaacccaca acatactatt tttgtatgtg ggtagattga
7921 atgccaagaa ctgtactgta gctataattt atccaggaaa actagacaca agattgactc
7981 tggaacgggg acagggaagg ccaagctgaa gtgacagtag catctgacac ttactgagcc
8041 ctaactctgt gctttaacac agccttgtga ggtcatcact gttattagca tccccatttt
8101 acagaggaag ccaccaacac atgaagtaaa aggatgggct gggcgcggtg gctcacgcct
8161 gtaatcccag cactttggga ggccgaggca ggcagatcac ttgaggtcag gagttcgaga
8221 tcagcctgac caacagacca acatggtgaa aacctggctc tactaaaaat acaaaaatta
8281 gctgggcctg gcggtgggtg cctgtactcc cagctacttg ggaggctgag gcaggagaat
8341 cacttgaacc tggaaggcag agattgcagt gagccgagac tgtgccactg cactctagcc
8401 tggacgacag agtgagactc catctcaaaa aaaaaaaaaa aagaagtaaa acgatgctcc
8461 aagggcaccc agttattaag gggcagagcc aaagctgaac ccagggaggc caaccctagc
8521 aatctgttaa attggaagaa ataatacaaa aactgtttta gcatttggcc agcctggatt
8581 tgagttttct cttttccttt cccaattatc aataagcagg aatatagaca aaaggctaaa
8641 gaaatgcacc tgtgaactat tcagcttgag cagctgacat tgacacctac aagtgctttt
8701 caggatactt ttgaactact gggcaggtgg gatggagaaa taaattacta tttccccagc
8761 aactgttctg ggctgagcac aagggcactt tttaaggagg tcaccccaca cccatcacac
8821 acacatagga cccctggaat cctaggaata aataagcatg gatttgtaaa atccaaacct
8881 ctcttttcaa atatcctcac ctggaccaga ccagaagaaa cctctacttt actctctaag
8941 ctgagagtgt ggaaggggaa acacgaggaa tggttcggct tcaggactaa ttgcggtgac
9001 acacaaccac ttctctttgc caccaaggac taccaggtac ctgcaaaggg cagtacttgg
9061 aggccagtgc tttctgctag ttagctcccg tggttttata gcagcccagg cgaaggaagg
9121 agaccccccc cagctcctgg cttctgttca gggaaagggg gccagagccc ctcctgatct
9181 gtccacacac ctgctctgtg ccttggctga ggcccctgca gctctacaag gcaggcattc
9241 tgctggatag gccaagcagg gtcactctga cacccaggtt tccaccccaa ggcatggcac
9301 aatgctggcc tcctgtgggt ggaatcaaag gctgagttct aacaggcttg cggcagacac
9361 acacacagag accacatgta catgatgaac acacatatcc ttttcattac aggttattag
9421 tacaagtttt ggaattgagc aaacaagagt ctaagcgctg gtttcaccac ttctcgtttg
9481 tgtgacctca gacaagtcat tcaacatctc tatgactcag tttccttatc tttatcacag
9541 agatgacacc cactctgaca gggccgaggg aagaaccata agcgatggca atgcaacaga
9601 gtggcacatg acaagagctc agcgaatttg agggaatgaa actgtagatt acaatactag
9661 tacaatatga taaacatatg atattgttag tgacatttat tttacttcta ctagcaaata
9721 acctatgttt aggactgact ttagaacagg ctggcagaag catttttggc agcatcaaag
9781 tcctccaacc tactggtctg ttggagcccc ccaagtacac caaagagcct ctgcattagc
9841 cctggctgag ggttcaggga caggcagaga agtacagcag tgagccatcc ctgcctgcat
9901 ggaggtggag aaatgatcag gcatggtcag ttgacaatct cctaaacaca gtaacccgtg
9961 tcataccaca gtgtaaacac acgtgcaaat gcttctgctt cctttcccca tcatgagaat
10021 agtcactcaa tgccgggcat cacaagggat caaatgctag gagtacccaa tcattcatgg
10081 atgcttctca aaggggacga gtgtctagaa gtgtaatttt aatttcactt aatttcatat
10141 ggaatcatct ccattactaa ttttgttcta attttaatgt gataatcact ttgtaaagca
10201 caataaacag aggcaggctc tcatgaggaa gtcagaagga aagaatccca agagacatgg
10261 gacagctcca tccaaactga aagggccgtg attcccaaaa gagcaatttt gtccccaagg
10321 tctgaagaca cttttggttg tcacaacctg gggggttgga gtaagcatta ctggtatcta
10381 gaagggggag gctggggatg ttgctaaaca ccctaccatg cacagggcag cccacattgc
10441 cacaaactat tatgtggccc aaatgtcaaa aatgctgagg ttgagaaacc ctgggtgagg
10501 cagactcagg gagaagggaa tcgagcttca ctcacaggca ggcaggagct gtctggtact
10561 tcaacctcca agacacctcc tgctcatctc atcctggctg ctctacccac cagctagaaa
10621 ccttgaacaa gttacttcac ttctttgtgc ctctgtttcc tcatatgtaa aagagggata
10681 acaaaacgca cacaacttgc atgttgctag gagcagaaat gagataatac aggaaaggtg
10741 ctgagaagaa tgcccggcac atggccagtt ctcaactact agtcacccat tactattagt
10801 tactcacatc ttagagctaa catagacatg ggcttattcc tggatacaca gcactgtccc
10861 catatctaca gtggtgatcc taagggcaac atggcatcac ccaaatgtct tgttagtcac
10921 tacagaatca cagtgtgagg gatgaaggcc atcaagacag agctgaggct ggcagggtgg
10981 ctcatgccta taatcccagt gctttggaag gctgaggcag gaggattgct tgaggccaag
11041 ggtttgagac cagcctaggt aacatagcaa gaccccatct acaattaaaa aaaaaaaaaa
11101 aaagacagaa agaaaaaata gccaggcgtg gcatgtgctt gtagtccaag ctactgggga
11161 gggaggctga ggcaggagga ttccttgagc ctgggagtgt gaggctgcag tgagctatga
11221 tggcatcgcc gcactccagc ctgcatgaca cagtgagacc tggtctcaaa aaccaaataa
11281 taataacagt aataaaagct ggaaagagct caaagttact catttgacag atgtgacaga
11341 tgaagaaata gaagcgagtt aggtgcctta ccatggtcaa acaactagtt cgtatcagac
11401 cctactccag aaactattcc agtccgggta acctctcgtt aacctctctt gttagaaatg
11461 caaatttctg cccaaatcag gcctcaggaa tcaagagact gtggggtcgg ctctgcaggc
11521 tatctgaatg aggcctccag ggaaatcaga ttcactctca agggtgagac gatttcccta
11581 aaggaacctt ctcataacag cctcttcctg tggcctttac aggatcctgg gtgaataaat
11641 tcccagtgga aatgacacac aaccacaact tccggctgaa tgagagagag gtagttaagg
11701 tttccatgat gcagaccaag gggaacttcc tcgcagcaaa tgaccaggag ctggactgcg
11761 acatcctcca gctggaatac gtggggggca tcagcatgct aattgtggtc ccacacaaga
11821 tgtctgggat gaagaccctc gaagcgcaac tgacaccccg ggtggtggag agatggcaaa
11881 aaagcatgac aaacaggtat ttcacactgt gtgtttgttc ttttgagctc ccagatgctg
11941 ggggtgtctg ggaatactgg aaaatggatc atttttttaa aaagggagaa ttatgtacaa
12001 gtacccaaga acttccatac agggccactc tgttaattca gccccaattt gttgcttgag
12061 ataagagatg attagagagc attcataagg gacacatctg ccctctaggg gccagtttca
12121 gaagttagag gcagatgact tagagacagc ttggtgcttg ctttgtggct tcgagtccca
12181 gcttcatcat ccctaaaatg ggtataattc cattacttcc ccgggtcact tgagaaaata
12241 acagaatcag cgatgctgag cgcccctccc agtacttgga acctaggagg cactcaaaaa
12301 aagattggct caactcttcc ctgcccagga aattccaagg tcctcttagc ctaccgagga
12361 cacatcattc atgatttcct ctattattat tcgttacttt gtagttaaaa ctgcaggtgt
12421 taagtactta ttgagattat tattgggtca tggcagaaag aatggagagg tcttatttct
12481 gtcttactgg atactggcta ggcccatatg aagaagtgat tctggtttga acctccttat
12541 aggacaagaa tacaaacata tgcaaccaaa ctgagaaaag taggctctca gaggaaggta
12601 tttgcccggg tagccagtca tcatgctctg tgaatttttc cttaacaacg tcccttctgt
12661 acctgcctcc ttccattcct ccctgcagcc cggcagctct tgagaaaggg actgcatctt
12721 tttttttttt ttttttttga gacagggtct tgttctgtca cccaggctgg agtgcagtgg
12781 catcatcatg gctcactgca gcctcaacct cctgaactta agtgatcctc tcacctcagc
12841 ctcctgaata gttgagacta caggcgtgca ccttcatgcc cagctaatta aacttttttt
12901 ggtagagatg aggtctcgct gtgttgccca ggctggtctt gaactcctgg cctcaagcag
12961 tcctcctgcc ttggccttcc aaagtgctgg gattaacagg cgtgagccgc tgtgcctggc
13021 ccatttgact tttaattgag atcttacttg gtgcaaggta tgagctaggt aaaagagtga
13081 agaagatcaa gccttcctgc ccatccagct gggattgcac cttaaatctc tttatcccct
13141 gcaaagtgcc agactaactc cacaggcact actgttgcta tccgccccct tagggattga
13201 gtaagttgag gcaaagattg agatattcag cattgtctag tatatacagg aaaggttctt
13261 tttaaaagta cactaccaga tattcgactc cttaattaca aaaaaaaaac caaatgccta
13321 aaattgggaa accaaaccag agaattattt tagatgcctt tttaaaccat aaaccaggaa
13381 aagttctgct gctaaccttg aagataggaa acgaaccata cagtctcaag gaaataatca
13441 tgcaacagaa aacacacctc agttttcagt agcggaatta caaaggagtg tgcttcctaa
13501 aatcctcaac tgacagtccc ggaatataaa ttttaataag tgctatatca attctgtgat
13561 aaatataacc cgtggccctt taaagggaaa atcatgattc ttttgtaact tgtggttcaa
13621 taaaactggg cccccctttc cttttctgtc tagaactcga gaagtgcttc tgccgaaatt
13681 caagctggag aagaactaca atctagtgga gtccctgaag ttgatgggga tcaggatgct
13741 gtttgacaaa aatggcaaca tggcaggcat ctcagaccaa aggatcgcca tcgacctggt
13801 aaccactccc ttgtccaccc ccgacccgtc cccagggtct gcctcagcac agccccacct
13861 ccacttgccc ttcctaccca ccccccaatc tcatgtccca gcttggggtg ctgagtctgc
13921 tcttcggcct gggtgggata cacagaatgc ctagtttcat ggatgccagc tggagagcac
13981 ggcacctggc agacacttac tgggcagggg ggatcccaag agcagccatg gggtgagccc
14041 cactcccgct gacaccagag acaggggaga catgtgctgc ggtctgggaa atagctaccc
14101 ccagccaaat catgaaagag ccattaaaca ccgcactata caacatactt aacttaaacc
14161 aatcgggtcg ctcagcaaaa gagagagaac accagtccaa acagtgcagc agacccagtt
14221 ccccatcccg gagaagtgcg cagcagtgtg gggagctgga gctggggtgg ctgtcctgca
14281 ccagccccca cgaccctcag accacaggca ctgccaagag ggaacatgaa cctagccggc
14341 ctctaagtgc aacggctgcc cctgacaggt ggtgacagat attttcaaga gtgactctga
14401 ccagctgtga tttccacctt acatgttgtc tttggatcct ttccctgaat gatatgagat
14461 tgtgctggga actctagccc tctgtgtgct gacctccaga atctgacaac tttcctttcc
14521 aaacagttca agcaccaagg cacgatcaca gtgaacgagg aaggcaccca agccaccact
14581 gtgaccacgg tggggttcat gccgctgtcc acccaagtcc gcttcactgt cgaccgcccc
14641 tttcttttcc tcatctacga gcatcgcacc agctgcctgc tcttcatggg aagagtggcc
14701 aaccccagca ggtcctagag gtggaggtct aggtgtctga agtgccttgg gggcaccctc
14761 attttgtttc cattccaaca acgagaacag agatgttctg gcatcattta cgtagtttac
14821 gctaccaatc tgaattcgag gcccatatga gaggagctta gaaacgacca agaagagagg
14881 cttgttggaa tcaattctgc acaatagccc atgctgtaag ctcatagaag tcactgtaac
14941 tgtagtgtgt ctgctgttac ctagagggtc tcacctcccc actcttcaca gcaaacctga
15001 gcagcgcgtc ctaagcacct cccgctccgg tgaccccatc cttgcacacc tgactctgtc
15061 actcaagcct ttctccacca ggcccctcat ctgaatacca agcacagaaa tgagtggtgt
15121 gactaattcc ttacctctcc caaggagggt acacaactag caccattctt gatgtccagg
15181 gaagaagcca cctcaagaca tatgaggggt gccctgggct aatgttaggg cttaattttc
15241 tcaaagcctg acctttcaaa tccatgatga atgccatcag tccctcctgc tgttgcctcc
15301 ctgtgacctg gaggacagtg tgtgccatgt ctcccatact agagataaat aaatgtagcc
15361 acatttactg tgtatctgtt ataattctct attttttgaa gctcaaatat caaaagccaa
15421 atccaaattc ctggataact ccaggtatga taaaggctga gaggaagtca cttgagcacc
15481 acaatgtgcc acagcagggc atgttctcag gacaggacag gtgtgtgctg aatcctgggg
15541 agggtctgtg cagtacccca gaactgtggg gtgctaagtg gcacacaagc cccagggctc
15601 ccacagtcta tgccaggctg ctgcagcttt catccctcat acctggtcct gcagtgggtc
15661 tggtttgaca gagcagatga cacctgagga atatgtttct ggatccttca atccctgggt
15721 aagacaagtg aaatccacag aggctgttca gcacgcaaga gtgccagtgc tctttcagtg
15781 aggggatgac tgacggtcac aggtgctgtg tgtgcaggtg tctaactgta accccacagc
15841 ctggcagat
//