GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI01 813 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 1.
ACCESSION M58642 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 1 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 813)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 485..749
/number=1
/gene="LACI"
exon 491..749
/number=1
/gene="LACI"
exon 513..749
/number=1
/gene="LACI"
BASE COUNT 292 a 151 c 146 g 224 t
ORIGIN
1 aaataactgg gctgagtagc aagttagcaa gtagctaagg tagggctcaa agctgacacc
61 tgcaatagat aatgcattac attgtctcac taagagagac ctccaacggt agccctcaga
121 cttttaaaaa aaataaatac attgacagtg ggtgaaacaa atgaaataac ttgaagaaga
181 aacaaactgc aaaaaagttt attaacagtg taataataaa tatgtaattt tttaaaccct
241 aactctaggg ggaaaaaagc attctttttc aactgattac aaaaacaatc ctggaaagta
301 aaggaaatag ctattcaaaa tgatcgtatc tgaaatcttg gtgtaagctg tttccttcat
361 ctgtttcctc cactaaaaaa aagaaagaaa gaaagaaaaa agaggtttag actaaataga
421 gtcagagttg cagtgaccta aacaggaagt tgggctattc ccaactgcca gtgatctctg
481 aagccgactc tgaggctccc tctttgctct aacagacagc agcgacttta ggctggataa
541 tagtcaaatt cttacctcgc tctttcactg ctagtaagat cagattgcgt ttctttcagt
601 tactcttcaa tcgccagttt cttgatctgc ttctaaaaga agaagtagag aagataaatc
661 ctgtcttcaa tacctggaag gaaaaacaaa ataacctcaa ctccgttttg aaaaaaacat
721 tccaagaact ttcatcagag attttacttg tgagtacctg gcaatatact gtctagccca
781 taagaaataa ctttaatttc tttttctcgg ggg
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI02 192 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 2.
ACCESSION M58643 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 2 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 192)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 61..184
/number=2
/gene="LACI"
BASE COUNT 60 a 45 c 47 g 40 t
ORIGIN
1 tgatgcctta aagaagcctt agagaaaaga tatctttctt tctctccatg gtgcacacag
61 gacaggaaag gccatgtgag gacataggga gaaagcagcc accattgcaa gccaagagag
121 agccctcacc aggaacgatt ggaccagcag caccttgatc ttggattttc tagcctccag
181 aactgtgaga ta
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI03 302 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 3.
ACCESSION M58644 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 3 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 302)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 91..213
/number=3
/gene="LACI"
BASE COUNT 91 a 49 c 57 g 105 t
ORIGIN
1 atatgaggta cacatatgat gtttactagt ctgtaaatga gtgcatatta acactttatt
61 tattagatat gtatgggttc tgtatttcag agatgattta cacaatgaag aaagtacatg
121 cactttgggc ttctgtatgc ctgctgctta atcttgcccc tgcccctctt aatgctgatt
181 ctgaggaaga tgaagaacac acaattatca caggtaaaat attagaagca attatctttt
241 taagctagtt aaagctctca attttaatct agggatctac catagttttc cattgtggag
301 gg
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI04 347 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 4.
ACCESSION M58645 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 4 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 347)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 85..282
/number=4
/gene="LACI"
BASE COUNT 116 a 47 c 72 g 112 t
ORIGIN
1 caggacatat taaaaaggaa ataaagaaca ttattacagt gttgatggag attacatgtt
61 atatctttta tttttacttt atagatacgg agttgccacc actgaaactt atgcattcat
121 tttgtgcatt caaggcggat gatggcccat gtaaagcaat catgaaaaga tttttcttca
181 atattttcac tcgacagtgc gaagaattta tatatggggg atgtgaagga aatcagaatc
241 gatttgaaag tctggaagag tgcaaaaaaa tgtgtacaag aggtaggttt ctgggaaccc
301 ttattactca aagacccttt aggctattga gtctaattat ggatttt
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI05 214 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 5.
ACCESSION M58646 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 5 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 214)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 68..106
/number=5
/gene="LACI"
BASE COUNT 68 a 24 c 34 g 88 t
ORIGIN
1 aaattcaaat tcatagtatt actttataaa tggtgacaat gatatgcata tattcttttg
61 attacagata atgcaaacag gattataaag acaacattgc aacaaggtga acatttattt
121 gtctgtaaat ttgaagcatt tatgtaaggc atttagatat tcaatttttt gtttgtttgc
181 ttgtttgttt tttctggtcc ctgattcagt atag
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI06 362 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 6.
ACCESSION M58647 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 6 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 362)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 97..273
/number=6
/gene="LACI"
BASE COUNT 118 a 50 c 62 g 132 t
ORIGIN
1 cttcaataac ttagccaggt atttataaat tttattaaaa tcagtaattt atttacacaa
61 aagaatattg ctttctgaca tttttataat ttctagaaaa gccagatttc tgctttttgg
121 aagaagatcc tggaatatgt cgaggttata ttaccaggta tttttataac aatcagacaa
181 aacagtgtga acgtttcaag tatggtggat gcctgggcaa tatgaacaat tttgagacac
241 tggaagaatg caagaacatt tgtgaagatg gtcgtaagtt tatttcttat ttcattttag
301 ttcatttata ggcatccttt taaaactaag gcatctcaga tggcattcta tactcaggtt
361 tt
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI07 239 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 7.
ACCESSION M58648 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 7 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 239)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 70..162
/number=7
/gene="LACI"
BASE COUNT 65 a 43 c 48 g 83 t
ORIGIN
1 cgcttcatga gtccaaatat gagattgtga caatgtttat ctattttaat tggctgtatt
61 tttttccagc gaatggtttc caggtggata attatggaac ccagctcaat gctgtgaata
121 actccctgac tccgcaatca accaaggttc ccagcctttt tggtaagaat cttgtggatt
181 ttattgcttc caggaaacta ttatcatgct aacaatgaag tggattgtgt attagaagt
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI08 339 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 8.
ACCESSION M58649 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 8 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 339)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 124..303
/number=8
/gene="LACI"
BASE COUNT 112 a 68 c 59 g 100 t
ORIGIN
1 cctttattca gattactgtt ttacatacac atgcaacaac attaatctat aaacaatata
61 caatacgaaa acctgaaatc cactatcaca catggcttac catgttttcc tgattgtttt
121 tagaatttca cggtccctca tggtgtctca ctccagcaga cagaggattg tgtcgtgcca
181 atgagaacag attctactac aattcagtca ttgggaaatg ccgcccattt aagtacagtg
241 gatgtggggg aaatgaaaac aattttactt ccaaacaaga atgtctgagg gcatgtaaaa
301 aaggtataga agatactctc ccattaattg actagtgtt
//GenBank-Updates@genbank.bio.net (02/21/91)
LOCUS HUMLACI09 2977 bp ds-DNA PRI 21-FEB-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 9.
ACCESSION M58650 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 9 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2977)
AUTHORS van der Logt,C.P., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein associated coagulation inhibitor; the factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry (1990) In press
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(M58642:485..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,
159..2950))
/gene="LACI"
mRNA join(M58642:491..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,
159..2950))
/gene="LACI"
mRNA join(M58642:513..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,
159..2950))
/gene="LACI"
exon one-of(159..313,159..2950)
/number=9
/gene="LACI"
CDS join(M58644:93..213,M58645:85..282,M58646:68..106,
M58647:97..273,M58648:70..162,M58649:124..303,160..266)
/product="lipoprotein associated coagulation inhibitor"
/gene="LACI"
/codon_start=93
BASE COUNT 913 a 540 c 429 g 1095 t
ORIGIN
1 aataaattgt tctacacgaa tacatggaca aattaaaggc ttttaaatca ataacatctt
61 ttggatttaa atattaaaag ttactttgag aagattttag ataaaacatt tcattgtgtt
121 attttatcac acattaattt attcctcttc cacttatagg tttcatccaa agaatatcaa
181 aaggaggcct aattaaaacc aaaagaaaaa gaaagaagca gagagtgaaa atagcatatg
241 aagaaatttt tgttaaaaat atgtgaattt gttatagcaa tgtaacatta attctactaa
301 atattttata tgaaatgttt cactatgatt ttctattttt cttctaaaat gcttttaatt
361 aatatgttca ttaaattttc tatgcttatt gtacttgtta tcaacacatt tgtatcagag
421 ttgcttttct aatcttgtta aattgcttat tctaggtctg taatttatta actggctact
481 gggaaattac ttattttctg gatctatctg tattttcatt taactacaaa ttatcatact
541 accggctaca tcaaatcagt cctttgattc catttggtga ccatctgttt gagaatatga
601 tcatgtaaat gattatctcc tttatagcct gtaaccagat taaggaatac agctcttaaa
661 aaatcaagaa cttcctgagt ttcacatata aaatggtgac aaacacctgc ttctgataaa
721 gtttatccaa ttttgtattt atagaattct attatgtgct tccctcctta gacatagttt
781 ttctcctttt gtactaacca gtacttccat ctatattgag ctaaactgtc tttgaacagt
841 caactctgca tcatgtgcct gcctgatttg gattggtttc actttttttt ttgtttgacc
901 atagcccatt ctatcagtca agatgactga ataattgtgt gttaaataca actcatgata
961 aggagaacct ttatggaaac aagaagtttt atggcaatcg agagggaatt atttatatgt
1021 acttcttaat actatgcttc ccaatatttt ttcttactaa aaataacaaa aatatttaaa
1081 ccttctgaaa tctattcagt tatcattagg atttgcacac aatgcaacta ataattcatg
1141 ctttaaaaag taggttattt ctgttgaaga gaaaattatc agcagggaag agtctactag
1201 aaaattcatg tgctagtcat tcttggggat ttaatatttt gctggagtta attcactata
1261 tccagacctg tatctttcat ttattgctga gccatgtgca gtctggcatc tcaacaacct
1321 caacaacctc aacaacctcc aagacatgtc agtttctgta gtgttcacct caaatctgac
1381 actggaattg gaactgattt agaaacaacc atttcattca tttggtatga ctagcttcat
1441 gactagcttc atgaatagct tcatgaatag cttcatgact tctcgctaac aatgatagta
1501 taattctgcc tgttcttcag gattgaaatt ttgaactcaa tttagatttc ctgttttccc
1561 tcatatacca catctaaaca gtctccaaat ctttatgctt tttttttttt tttcaaaaaa
1621 gttcacccaa tccctaggct ttttactttt ttctttttct tttctttttt cttgtttttt
1681 tttttttcat tttgttttgt tttgttatgt ttttttagac agggtcccac tctgtcaccc
1741 aggctggagt gcagtggtgc aatcacaggt cactgaaacc tcccacctag ctgggactag
1801 aggtgcaggc caccacacca gctaatttat gtaatttttg tagagacgag tttcaccacg
1861 ttacctaggc ttgtcttgaa cacctgggct caagcaatct tccagcccca gcctcccaaa
1921 gtgctgggat tacaggtata aaccacaatg cccccgtttt tactctttac tgcatccttc
1981 ccatcagtat taattcctca gaaatttagt acattcctcc accatttcaa aatgctccca
2041 gaactcacac tagttggtac ttaactacaa ccttcaacct caccatttaa ttttgatgta
2101 tgtttttgga tttaccaaca gtactttctt tcatgactac tttgatttag ttaagaatgc
2161 tcactgtaca ctgaatgtta attactcagc taattcacac tgatttcctg tttaaaaata
2221 tgatcccctc caggccattc atgtgaagtc agggtacagc tgatgccagc tacagaatca
2281 ctatgtttca atatggaata tgaaaagtcc taacacataa ttgcaaatca ttttctacta
2341 tggtatacaa attttatcat tacaaaatag tatcagcttt tttcacttaa ggaaaataat
2401 acatcttcat tcaaatattc agtgcataaa taattgcctt aaattgagtc tttgctgtgg
2461 aatttgagag ttttggaaat caaaggccct tgtgaaacat ttcctgttgc catttattta
2521 tagatagcaa tagcttcaaa tgagtgggaa agtctactta ggtgaagtgg taaatagtca
2581 ctaagattgt ataaatagcg cattgatgag ttgcctaatt gttttctcca acaataacca
2641 ctggtccatt ggttcactac ttactcaaga aagacatata ctgagatggc ttgaaatgtt
2701 taatgcatgt gaacgttatt tttaccgtgt tttggaaaaa gatcttgatg ttattgtctt
2761 cctttatttt ccacaattaa gtgcatctaa ctgtgaattg tatatggaat tacattattc
2821 agcatataca tatatttacc tgctttgttc attctctgta ttcaaaatta acagatcatg
2881 ctgaaaacca ctcaaacgat tatatttttt acattataag aagtaaaata tattattctg
2941 aataatgaaa ccaggcagtt gtactcgtaa agatttt
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI01 813 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 1.
ACCESSION M58642 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 1 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 813)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 485..749
/number=1
/gene="LACI"
exon 491..749
/number=1
/gene="LACI"
exon 513..749
/number=1
/gene="LACI"
BASE COUNT 292 a 151 c 146 g 224 t
ORIGIN
1 aaataactgg gctgagtagc aagttagcaa gtagctaagg tagggctcaa agctgacacc
61 tgcaatagat aatgcattac attgtctcac taagagagac ctccaacggt agccctcaga
121 cttttaaaaa aaataaatac attgacagtg ggtgaaacaa atgaaataac ttgaagaaga
181 aacaaactgc aaaaaagttt attaacagtg taataataaa tatgtaattt tttaaaccct
241 aactctaggg ggaaaaaagc attctttttc aactgattac aaaaacaatc ctggaaagta
301 aaggaaatag ctattcaaaa tgatcgtatc tgaaatcttg gtgtaagctg tttccttcat
361 ctgtttcctc cactaaaaaa aagaaagaaa gaaagaaaaa agaggtttag actaaataga
421 gtcagagttg cagtgaccta aacaggaagt tgggctattc ccaactgcca gtgatctctg
481 aagccgactc tgaggctccc tctttgctct aacagacagc agcgacttta ggctggataa
541 tagtcaaatt cttacctcgc tctttcactg ctagtaagat cagattgcgt ttctttcagt
601 tactcttcaa tcgccagttt cttgatctgc ttctaaaaga agaagtagag aagataaatc
661 ctgtcttcaa tacctggaag gaaaaacaaa ataacctcaa ctccgttttg aaaaaaacat
721 tccaagaact ttcatcagag attttacttg tgagtacctg gcaatatact gtctagccca
781 taagaaataa ctttaatttc tttttctcgg ggg
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI02 192 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 2.
ACCESSION M58643 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 2 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 192)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 61..184
/number=2
/gene="LACI"
BASE COUNT 60 a 45 c 47 g 40 t
ORIGIN
1 tgatgcctta aagaagcctt agagaaaaga tatctttctt tctctccatg gtgcacacag
61 gacaggaaag gccatgtgag gacataggga gaaagcagcc accattgcaa gccaagagag
121 agccctcacc aggaacgatt ggaccagcag caccttgatc ttggattttc tagcctccag
181 aactgtgaga ta
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI03 302 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 3.
ACCESSION M58644 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 3 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 302)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 91..213
/number=3
/gene="LACI"
BASE COUNT 91 a 49 c 57 g 105 t
ORIGIN
1 atatgaggta cacatatgat gtttactagt ctgtaaatga gtgcatatta acactttatt
61 tattagatat gtatgggttc tgtatttcag agatgattta cacaatgaag aaagtacatg
121 cactttgggc ttctgtatgc ctgctgctta atcttgcccc tgcccctctt aatgctgatt
181 ctgaggaaga tgaagaacac acaattatca caggtaaaat attagaagca attatctttt
241 taagctagtt aaagctctca attttaatct agggatctac catagttttc cattgtggag
301 gg
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI04 347 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 4.
ACCESSION M58645 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 4 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 347)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 85..282
/number=4
/gene="LACI"
BASE COUNT 116 a 47 c 72 g 112 t
ORIGIN
1 caggacatat taaaaaggaa ataaagaaca ttattacagt gttgatggag attacatgtt
61 atatctttta tttttacttt atagatacgg agttgccacc actgaaactt atgcattcat
121 tttgtgcatt caaggcggat gatggcccat gtaaagcaat catgaaaaga tttttcttca
181 atattttcac tcgacagtgc gaagaattta tatatggggg atgtgaagga aatcagaatc
241 gatttgaaag tctggaagag tgcaaaaaaa tgtgtacaag aggtaggttt ctgggaaccc
301 ttattactca aagacccttt aggctattga gtctaattat ggatttt
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI05 214 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 5.
ACCESSION M58646 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 5 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 214)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 68..106
/number=5
/gene="LACI"
BASE COUNT 68 a 24 c 34 g 88 t
ORIGIN
1 aaattcaaat tcatagtatt actttataaa tggtgacaat gatatgcata tattcttttg
61 attacagata atgcaaacag gattataaag acaacattgc aacaaggtga acatttattt
121 gtctgtaaat ttgaagcatt tatgtaaggc atttagatat tcaatttttt gtttgtttgc
181 ttgtttgttt tttctggtcc ctgattcagt atag
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI06 362 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 6.
ACCESSION M58647 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 6 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 362)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 97..273
/number=6
/gene="LACI"
BASE COUNT 118 a 50 c 62 g 132 t
ORIGIN
1 cttcaataac ttagccaggt atttataaat tttattaaaa tcagtaattt atttacacaa
61 aagaatattg ctttctgaca tttttataat ttctagaaaa gccagatttc tgctttttgg
121 aagaagatcc tggaatatgt cgaggttata ttaccaggta tttttataac aatcagacaa
181 aacagtgtga acgtttcaag tatggtggat gcctgggcaa tatgaacaat tttgagacac
241 tggaagaatg caagaacatt tgtgaagatg gtcgtaagtt tatttcttat ttcattttag
301 ttcatttata ggcatccttt taaaactaag gcatctcaga tggcattcta tactcaggtt
361 tt
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI07 239 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 7.
ACCESSION M58648 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 7 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 239)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 70..162
/number=7
/gene="LACI"
BASE COUNT 65 a 43 c 48 g 83 t
ORIGIN
1 cgcttcatga gtccaaatat gagattgtga caatgtttat ctattttaat tggctgtatt
61 tttttccagc gaatggtttc caggtggata attatggaac ccagctcaat gctgtgaata
121 actccctgac tccgcaatca accaaggttc ccagcctttt tggtaagaat cttgtggatt
181 ttattgcttc caggaaacta ttatcatgct aacaatgaag tggattgtgt attagaagt
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI08 339 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 8.
ACCESSION M58649 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 8 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 339)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 124..303
/number=8
/gene="LACI"
BASE COUNT 112 a 68 c 59 g 100 t
ORIGIN
1 cctttattca gattactgtt ttacatacac atgcaacaac attaatctat aaacaatata
61 caatacgaaa acctgaaatc cactatcaca catggcttac catgttttcc tgattgtttt
121 tagaatttca cggtccctca tggtgtctca ctccagcaga cagaggattg tgtcgtgcca
181 atgagaacag attctactac aattcagtca ttgggaaatg ccgcccattt aagtacagtg
241 gatgtggggg aaatgaaaac aattttactt ccaaacaaga atgtctgagg gcatgtaaaa
301 aaggtataga agatactctc ccattaattg actagtgtt
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMLACI09 2977 bp ds-DNA PRI 14-MAR-1991
DEFINITION Human lipoprotein associated coagulation inhibitor (LACI) gene,
exon 9.
ACCESSION M58650 J05312
KEYWORDS lipoprotein associated coagulation inhibitor.
SEGMENT 9 of 9
SOURCE Human peripheral blood leukocyte DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2977)
AUTHORS van der Logt,C.E., Reitsma,P.H. and Bertina,R.M.
TITLE Intron-exon organization of the human gene coding for the
lipoprotein-associated coagulation inhibitor: The factor Xa
dependent inhibitor of the extrinsic pathway of coagulation
JOURNAL Biochemistry 30, 1571-1577 (1991)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
mRNA join(M58642:485..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,159..2950))
/gene="LACI"
mRNA join(M58642:491..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,159..2950))
/gene="LACI"
mRNA join(M58642:513..749,M58643:61..184,M58644:91..213,
M58645:85..282,M58646:68..106,M58647:97..273,
M58648:70..162,M58649:124..303,one-of(159..313,159..2950))
/gene="LACI"
exon one-of(159..313,159..2950)
/number=9
/gene="LACI"
CDS join(M58644:93..213,M58645:85..282,M58646:68..106,
M58647:97..273,M58648:70..162,M58649:124..303,160..266)
/product="lipoprotein associated coagulation inhibitor"
/gene="LACI"
/codon_start=93
BASE COUNT 913 a 540 c 429 g 1095 t
ORIGIN
1 aataaattgt tctacacgaa tacatggaca aattaaaggc ttttaaatca ataacatctt
61 ttggatttaa atattaaaag ttactttgag aagattttag ataaaacatt tcattgtgtt
121 attttatcac acattaattt attcctcttc cacttatagg tttcatccaa agaatatcaa
181 aaggaggcct aattaaaacc aaaagaaaaa gaaagaagca gagagtgaaa atagcatatg
241 aagaaatttt tgttaaaaat atgtgaattt gttatagcaa tgtaacatta attctactaa
301 atattttata tgaaatgttt cactatgatt ttctattttt cttctaaaat gcttttaatt
361 aatatgttca ttaaattttc tatgcttatt gtacttgtta tcaacacatt tgtatcagag
421 ttgcttttct aatcttgtta aattgcttat tctaggtctg taatttatta actggctact
481 gggaaattac ttattttctg gatctatctg tattttcatt taactacaaa ttatcatact
541 accggctaca tcaaatcagt cctttgattc catttggtga ccatctgttt gagaatatga
601 tcatgtaaat gattatctcc tttatagcct gtaaccagat taaggaatac agctcttaaa
661 aaatcaagaa cttcctgagt ttcacatata aaatggtgac aaacacctgc ttctgataaa
721 gtttatccaa ttttgtattt atagaattct attatgtgct tccctcctta gacatagttt
781 ttctcctttt gtactaacca gtacttccat ctatattgag ctaaactgtc tttgaacagt
841 caactctgca tcatgtgcct gcctgatttg gattggtttc actttttttt ttgtttgacc
901 atagcccatt ctatcagtca agatgactga ataattgtgt gttaaataca actcatgata
961 aggagaacct ttatggaaac aagaagtttt atggcaatcg agagggaatt atttatatgt
1021 acttcttaat actatgcttc ccaatatttt ttcttactaa aaataacaaa aatatttaaa
1081 ccttctgaaa tctattcagt tatcattagg atttgcacac aatgcaacta ataattcatg
1141 ctttaaaaag taggttattt ctgttgaaga gaaaattatc agcagggaag agtctactag
1201 aaaattcatg tgctagtcat tcttggggat ttaatatttt gctggagtta attcactata
1261 tccagacctg tatctttcat ttattgctga gccatgtgca gtctggcatc tcaacaacct
1321 caacaacctc aacaacctcc aagacatgtc agtttctgta gtgttcacct caaatctgac
1381 actggaattg gaactgattt agaaacaacc atttcattca tttggtatga ctagcttcat
1441 gactagcttc atgaatagct tcatgaatag cttcatgact tctcgctaac aatgatagta
1501 taattctgcc tgttcttcag gattgaaatt ttgaactcaa tttagatttc ctgttttccc
1561 tcatatacca catctaaaca gtctccaaat ctttatgctt tttttttttt tttcaaaaaa
1621 gttcacccaa tccctaggct ttttactttt ttctttttct tttctttttt cttgtttttt
1681 tttttttcat tttgttttgt tttgttatgt ttttttagac agggtcccac tctgtcaccc
1741 aggctggagt gcagtggtgc aatcacaggt cactgaaacc tcccacctag ctgggactag
1801 aggtgcaggc caccacacca gctaatttat gtaatttttg tagagacgag tttcaccacg
1861 ttacctaggc ttgtcttgaa cacctgggct caagcaatct tccagcccca gcctcccaaa
1921 gtgctgggat tacaggtata aaccacaatg cccccgtttt tactctttac tgcatccttc
1981 ccatcagtat taattcctca gaaatttagt acattcctcc accatttcaa aatgctccca
2041 gaactcacac tagttggtac ttaactacaa ccttcaacct caccatttaa ttttgatgta
2101 tgtttttgga tttaccaaca gtactttctt tcatgactac tttgatttag ttaagaatgc
2161 tcactgtaca ctgaatgtta attactcagc taattcacac tgatttcctg tttaaaaata
2221 tgatcccctc caggccattc atgtgaagtc agggtacagc tgatgccagc tacagaatca
2281 ctatgtttca atatggaata tgaaaagtcc taacacataa ttgcaaatca ttttctacta
2341 tggtatacaa attttatcat tacaaaatag tatcagcttt tttcacttaa ggaaaataat
2401 acatcttcat tcaaatattc agtgcataaa taattgcctt aaattgagtc tttgctgtgg
2461 aatttgagag ttttggaaat caaaggccct tgtgaaacat ttcctgttgc catttattta
2521 tagatagcaa tagcttcaaa tgagtgggaa agtctactta ggtgaagtgg taaatagtca
2581 ctaagattgt ataaatagcg cattgatgag ttgcctaatt gttttctcca acaataacca
2641 ctggtccatt ggttcactac ttactcaaga aagacatata ctgagatggc ttgaaatgtt
2701 taatgcatgt gaacgttatt tttaccgtgt tttggaaaaa gatcttgatg ttattgtctt
2761 cctttatttt ccacaattaa gtgcatctaa ctgtgaattg tatatggaat tacattattc
2821 agcatataca tatatttacc tgctttgttc attctctgta ttcaaaatta acagatcatg
2881 ctgaaaacca ctcaaacgat tatatttttt acattataag aagtaaaata tattattctg
2941 aataatgaaa ccaggcagtt gtactcgtaa agatttt
//