GenBank-Updates@genbank.bio.net (12/06/90)
LOCUS HUMTNFBP 2050 bp ss-mRNA PRI 06-DEC-1990
DEFINITION Human tumor necrosis factor receptor(TNF) mRNA, complete cds.
ACCESSION M37764
KEYWORDS TNF receptor; transmembrane receptor;
tumor necrosis factor receptor.
SOURCE Human placenta, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2050)
AUTHORS Gray,P.W., Barrett,K., Chantry,D., Turner,M. and Feldman,M.
TITLE Cloning of human tumor necrosis factor (TNF) receptor cDNA and
expression of recombinant soluble TNF-binding protein
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 7380-7384 (1990)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Proc. Natl. Acad.
Sci. U.S.A. (1990) In press] kindly submitted by P.W.Gray,
13-AUG-1990.
FEATURES from to/span description
pept 155 1516 TNF receptor precursor
sigp 155 274 TNF receptor signal peptide
matp 275 1513 TNF receptor
BASE COUNT 429 a 611 c 566 g 444 t
ORIGIN
1 accagtgatc tctatgcccg agtctcaacc ctcaactgtc accccaaggc acttgggacg
61 tcctggacag accgagtccc gggaagcccc agcactgccg ctgccacact gccctgagcc
121 caaatggggg agtgagaggc catagctgtc tggcatgggc ctctccaccg tgcctgacct
181 gctgctgccg ctggtgctcc tggagctgtt ggtgggaata tacccctcag gggttattgg
241 actggtccct cacctagggg acagggagaa gagagatagt gtgtgtcccc aaggaaaata
301 tatccaccct caaaataatt cgatttgctg taccaagtgc cacaaaggaa cctacttgta
361 caatgactgt ccaggcccgg ggcaggatac ggactgcagg gagtgtgaga gcggctcctt
421 caccgcttca gaaaaccacc tcagacactg cctcagctgc tccaaatgcc gaaaggaaat
481 gggtcaggtg gagatctctt cttgcacagt ggaccgggac accgtgtgtg gctgcaggaa
541 gaaccagtac cggcattatt ggagtgaaaa ccttttccag tgcttcaatt gcagcctctg
601 cctcaatggg accgtgcacc tctcctgcca ggagaaacag aacaccgtgt gcacctgcca
661 tgcaggtttc tttctaagag aaaacgagtg tgtctcctgt agtaactgta agaaaagcct
721 ggagtgcacg aagttgtgcc taccccagat tgagaatgtt aagggcactg aggactcagg
781 caccacagtg ctgttgcccc tggtcatttt ctttggtctt tgccttttat ccctcctctt
841 cattggttta atgtatcgct accaacggtg gaagtccaag ctctactcca ttgtttgtgg
901 gaaatcgaca cctgaaaaag agggggagct tgaaggaact actactaagc ccctggcccc
961 aaacccaagc ttcagtccca ctccaggctt cacccccacc ctgggcttca gtcccgtgcc
1021 cagttccacc ttcacctcca gctccaccta tacccccggt gactgtccca actttgcggc
1081 tccccgcaga gaggtggcac caccctatca gggggctgac cccatccttg cgacagccct
1141 cgcctccgac cccatcccca acccccttca gaagtgggag gacagtgccc acaagccaca
1201 gagcctagac actgatgacc ccgcgacgct gtacgccgtg gtggagaacg tgcccccgtt
1261 gcgctggaag gaattcgtgc ggcgcctagg gctgagcgac cacgagatcg atcggctgga
1321 gctgcagaac gggcgctgcc tgcgcgaggc gcaatacagc atgctggcga cctggaggcg
1381 gcgcacccgg cgcgaggcca cgctggagct gctgggacgc gtgctccgcg acatggacct
1441 gctgggctgc ttggaggaca tcgaggaggc gctttgcgcc ccgccgctcc cgcccgcgcc
1501 cagtcttctc agatgaggct gcgccctgcg gcagctctaa ggaccgtcct cggagatcgc
1561 cttccaaccc cacttttttc tggaaaggag gggtcctgca ggggaagcag gagctagcag
1621 ccgcctactt ggtgctaacc cctcgatgta catagctttt ctcagctgcc tgcgcgccgc
1681 cgacagtcag ctgtgcgcgc ggagagaggt ggcccgtggc tcaagagcct gagtgggtgg
1741 tttgcgagga tgagggacgc tatgcctcat gcccgttttg ggtgtcctca ccagcaaggc
1801 tgctcggggg cccctggttc gtccctgagc ctttttcaca gtgcataagc agtttttttt
1861 gtttttgttt tgttttgttt tgtttttaaa tcaatcatgt tacactaata gaaacttcga
1921 ctcctgtgcc ctctgcctgg acaagcacat agcaagctga actgtcctaa ggcaggggcg
1981 agcacggaac aatggggcct tcagctggag ctgtggactt ttgtacatac actaaaattc
2041 tgaagttaag
//GenBank-Updates@genbank.bio.net (01/31/91)
LOCUS HUMTNFRP 2050 bp ss-mRNA PRI 31-JAN-1991
DEFINITION Human tumor necrosis factor receptor(TNF) mRNA, complete cds.
ACCESSION M60275 M37764
KEYWORDS TNF receptor; transmembrane receptor;
tumor necrosis factor receptor.
SOURCE Human placenta, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2050)
AUTHORS Gray,P.W., Barrett,K., Chantry,D., Turner,M. and Feldman,M.
TITLE Cloning of human tumor necrosis factor (TNF) receptor cDNA and
expression of recombinant soluble TNF-binding protein
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 7380-7384 (1990)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Proc. Natl. Acad.
Sci. U.S.A. (1990) In press] kindly submitted
by P.W.Gray, 13-AUG-1990.
FEATURES Location/Qualifiers
CDS 155..1516
/product="TNF receptor"
/codon_start=155
sig_peptide 155..274
/gene="TNF receptor"
/codon_start=155
mat_peptide 275..1513
/product="TNF receptor"
/codon_start=275
BASE COUNT 429 a 611 c 566 g 444 t
ORIGIN
1 accagtgatc tctatgcccg agtctcaacc ctcaactgtc accccaaggc acttgggacg
61 tcctggacag accgagtccc gggaagcccc agcactgccg ctgccacact gccctgagcc
121 caaatggggg agtgagaggc catagctgtc tggcatgggc ctctccaccg tgcctgacct
181 gctgctgccg ctggtgctcc tggagctgtt ggtgggaata tacccctcag gggttattgg
241 actggtccct cacctagggg acagggagaa gagagatagt gtgtgtcccc aaggaaaata
301 tatccaccct caaaataatt cgatttgctg taccaagtgc cacaaaggaa cctacttgta
361 caatgactgt ccaggcccgg ggcaggatac ggactgcagg gagtgtgaga gcggctcctt
421 caccgcttca gaaaaccacc tcagacactg cctcagctgc tccaaatgcc gaaaggaaat
481 gggtcaggtg gagatctctt cttgcacagt ggaccgggac accgtgtgtg gctgcaggaa
541 gaaccagtac cggcattatt ggagtgaaaa ccttttccag tgcttcaatt gcagcctctg
601 cctcaatggg accgtgcacc tctcctgcca ggagaaacag aacaccgtgt gcacctgcca
661 tgcaggtttc tttctaagag aaaacgagtg tgtctcctgt agtaactgta agaaaagcct
721 ggagtgcacg aagttgtgcc taccccagat tgagaatgtt aagggcactg aggactcagg
781 caccacagtg ctgttgcccc tggtcatttt ctttggtctt tgccttttat ccctcctctt
841 cattggttta atgtatcgct accaacggtg gaagtccaag ctctactcca ttgtttgtgg
901 gaaatcgaca cctgaaaaag agggggagct tgaaggaact actactaagc ccctggcccc
961 aaacccaagc ttcagtccca ctccaggctt cacccccacc ctgggcttca gtcccgtgcc
1021 cagttccacc ttcacctcca gctccaccta tacccccggt gactgtccca actttgcggc
1081 tccccgcaga gaggtggcac caccctatca gggggctgac cccatccttg cgacagccct
1141 cgcctccgac cccatcccca acccccttca gaagtgggag gacagtgccc acaagccaca
1201 gagcctagac actgatgacc ccgcgacgct gtacgccgtg gtggagaacg tgcccccgtt
1261 gcgctggaag gaattcgtgc ggcgcctagg gctgagcgac cacgagatcg atcggctgga
1321 gctgcagaac gggcgctgcc tgcgcgaggc gcaatacagc atgctggcga cctggaggcg
1381 gcgcacccgg cgcgaggcca cgctggagct gctgggacgc gtgctccgcg acatggacct
1441 gctgggctgc ttggaggaca tcgaggaggc gctttgcgcc ccgccgctcc cgcccgcgcc
1501 cagtcttctc agatgaggct gcgccctgcg gcagctctaa ggaccgtcct cggagatcgc
1561 cttccaaccc cacttttttc tggaaaggag gggtcctgca ggggaagcag gagctagcag
1621 ccgcctactt ggtgctaacc cctcgatgta catagctttt ctcagctgcc tgcgcgccgc
1681 cgacagtcag ctgtgcgcgc ggagagaggt ggcccgtggc tcaagagcct gagtgggtgg
1741 tttgcgagga tgagggacgc tatgcctcat gcccgttttg ggtgtcctca ccagcaaggc
1801 tgctcggggg cccctggttc gtccctgagc ctttttcaca gtgcataagc agtttttttt
1861 gtttttgttt tgttttgttt tgtttttaaa tcaatcatgt tacactaata gaaacttcga
1921 ctcctgtgcc ctctgcctgg acaagcacat agcaagctga actgtcctaa ggcaggggcg
1981 agcacggaac aatggggcct tcagctggag ctgtggactt ttgtacatac actaaaattc
2041 tgaagttaag
//GenBank-Updates@genbank.bio.net (03/14/91)
LOCUS HUMTNFRC 2112 bp ss-mRNA PRI 14-MAR-1991
DEFINITION Human tumor necrosis factor receptor (TNF receptor) mRNA, complete
cds.
ACCESSION M63121
KEYWORDS tumor necrosis factor receptor.
SOURCE Human cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2112)
AUTHORS Himmler,A., Maurer-Fogy,I., Kroenke,M., Scheurich,P.,
Pfizenmaier,K., Lantz,M., Olsson,I., Hauptmann,R., Stratowa,C. and
Adolf,G.R.
TITLE Molecular cloning and expression of human and rat tumor necrosis
factor receptor chain (p60) and its soluble derivative, tumor
necrosis factor-binding protein
JOURNAL DNA Cell Biol. 9, 705-715 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
sig_peptide 207..293
/gene="TNF receptor"
/codon_start=207
CDS 207..1574
/product="tumor necrosis factor receptor"
/gene="TNF receptor"
/codon_start=207
mat_peptide 294..1571
/product="tumor necrosis factor receptor"
/gene="TNF receptor"
/codon_start=294
BASE COUNT 435 a 632 c 589 g 456 t
ORIGIN
1 tctggactga ggctccagtt ctggcctttg gggttcaaga tcactgggac caggccgtga
61 tctctatgcc cgagtctcaa ccctcaactg tcaccccaag gcacttggga cgtcctggac
121 agaccgagtc ccgggaagcc ccagcactgc cgctgccaca ctgccctgag cccaaatggg
181 ggagtgagag gccatagctg tctggcatgg gcctctccac cgtgcctgac ctgctgctgc
241 cactggtgct cctggagctg ttggtgggaa tatacccctc aggggttatt ggactggtcc
301 ctcacctagg ggacagggag aagagagata gtgtgtgtcc ccaaggaaaa tatatccacc
361 ctcaaaataa ttcgatttgc tgtaccaagt gccacaaagg aacctacttg tacaatgact
421 gtccaggccc ggggcaggat acggactgca gggagtgtga gagcggctcc ttcaccgctt
481 cagaaaacca cctcagacac tgcctcagct gctccaaatg ccgaaaggaa atgggtcagg
541 tggagatctc ttcttgcaca gtggaccggg acaccgtgtg tggctgcagg aagaaccagt
601 accggcatta ttggagtgaa aaccttttcc agtgcttcaa ttgcagcctc tgcctcaatg
661 ggaccgtgca cctctcctgc caggagaaac agaacaccgt gtgcacctgc catgcaggtt
721 tctttctaag agaaaacgag tgtgtctcct gtagtaactg taagaaaagc ctggagtgca
781 cgaagttgtg cctaccccag attgagaatg ttaagggcac tgaggactca ggcaccacag
841 tgctgttgcc cctggtcatt ttctttggtc tttgcctttt atccctcctc ttcattggtt
901 taatgtatcg ctaccaacgg tggaagtcca agctctactc cattgtttgt gggaaatcga
961 cacctgaaaa agagggggag cttgaaggaa ctactactaa gcccctggcc ccaaacccaa
1021 gcttcagtcc cactccaggc ttcaccccca ccctgggctt cagtcccgtg cccagttcca
1081 ccttcacctc cagctccacc tatacccccg gtgactgtcc caactttgcg gctccccgca
1141 gagaggtggc accaccctat cagggggctg accccatcct tgcgacagcc ctcgcctccg
1201 accccatccc caaccccctt cagaagtggg aggacagcgc ccacaagcca cagagcctag
1261 acactgatga ccccgcgacg ctgtacgccg tggtggagaa cgtgcccccg ttgcgctgga
1321 aggaattcgt gcggcgccta gggctgagcg accacgagat cgatcggctg gagctgcaga
1381 acgggcgctg cctgcgcgag gcgcaataca gcatgctggc gacctggagg cggcgcacgc
1441 cgcggcgcga ggccacgctg gagctgctgg gacgcgtgct ccgcgacatg gacctgctgg
1501 gctgcctgga ggacatcgag gaggcgcttt gcggccccgc cgccctcccg cccgcgccca
1561 gtcttctcag atgaggctgc gcccctgcgg gcagctctaa ggaccgtcct gcgagatcgc
1621 cttccaaccc cacttttttc tggaaaggag gggtcctgca ggggcaagca ggagctagca
1681 gccgcctact tggtgctaac ccctcgatgt acatagcttt tctcagctgc ctgcgcgccg
1741 ccgacagtca gcgctgtgcg cgcggagaga ggtgcgccgt gggctcaaga gcctgagtgg
1801 gtggtttgcg aggatgaggg acgctatgcc tcatgcccgt tttgggtgtc ctcaccagca
1861 aggctgctcg ggggcccctg gttcgtccct gagccttttt cacagtgcat aagcagtttt
1921 ttttgttttt gttttgtttt gttttgtttt taaatcaatc atgttacact aatagaaact
1981 tggcactcct gtgccctctg cctggacaag cacatagcaa gctgaactgt cctaaggcag
2041 gggcgagcac ggaacaatgg ggccttcagc tggagctgtg gacttttgta catacactaa
2101 aattctgaag tt
//