GenBank-Updates@genbank.bio.net (03/15/91)
LOCUS YSCXRN1 5794 bp ds-DNA PLN 15-MAR-1991
DEFINITION Saccharomyces cerevisiae XRN1 gene encoding 5'-3' exoribonuclease,
complete cds.
ACCESSION M62423
KEYWORDS 5'-3' exoribonuclease; RNA turnover.
SOURCE Saccharomyces cerevisiae (strain S288C) DNA.
ORGANISM Saccharomyces cerevisiae
Eukaryota; Plantae; Thallobionta; Eumycota; Hemiascomycetes;
Endomycetales; Saccharomycetaceae.
REFERENCE 1 (sites)
AUTHORS Larimer,F.W. and Stevens,A.
TITLE Distruption of the gene XRN1, coding for a 5' 3' exoribonuclease,
restricts yeast cell growth
JOURNAL Gene 95, 85-90 (1990)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 5794)
AUTHORS Larimer,F.W. and Stevens,A.
TITLE Structure of the XRN1 exoribonuclease gene of Saccharomyces
cerevisiae
JOURNAL Unpublished (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 781..5367
/product="5'-3' exoribonuclease"
/gene="XRN1"
/codon_start=781
BASE COUNT 1875 a 1067 c 1125 g 1727 t
ORIGIN
1 aaatgatgca cctaatcctc ctgtagatcc ggctggttta gcgccaaata gtccacctgt
61 acttgggccg gtgttttgtc cagtttgagt cccaccaaac gaaaacccag tattcgcgtt
121 tccagtgcta cgtccgctgg cctgaccaaa gagccacctg caggtgtcga agatgcttta
181 tttaatccaa acattgtgcc cactacccgt gaaaaccctc tcaattactg tttttatcgt
241 ctcatcacct gatcagtaac tattctcacg attaatggtc tttttcaact acatttattt
301 gagaaagctg taatacattc cgtgttgagt gatatataca acctcctttg ctcgtctttt
361 cgccaccgca gagcaagtaa caacagagac aaacaagaag aggttagaaa gcaatttaag
421 gagtagttta acgagtactg aaaacgtcaa actaagtact tacgacttcc aattaccggt
481 tgtaaagttt atctacgcaa atataacagt tgcagcttgc tttttttttc agcagctctt
541 ccgttattat aaaatctgtt tggcgttcgc acaagcgaac cgattctttt attattttct
601 ctctgccttt tatttccgtt cctgttaata gtttattttc taaaggatac tgtcttcttc
661 cgtacttata atcgggttca caataagcaa ttgactaatc ctaggacgat tcgtgtacta
721 taaggagaaa aaaaatcaac acttgtaaca acagcagcaa caaatatata tcagtacggt
781 atgggtattc caaaattttt caggtacatc tcagaaagat ggcccatgat tttacagctt
841 attgagggaa cacagattcc tgagtttgat aacttatacc tggatatgaa ttcgatttta
901 cataattgta cgcatggtaa cgacgatgat gtaaccaagc gattaactga agaagaggtt
961 tttgcaaaaa tctgtacgta tatcgatcac ctttttcaaa caatcaagcc caagaagatt
1021 ttctacatgg ctattgatgg tgtggcccct cgtgccaaga tgaatcaaca aagagctcgt
1081 agattcagaa ccgctatgga tgcagaaaaa gccttgaaga aggctattga gaatggtgac
1141 gagattccta agggtgagcc atttgattcg aattctatta ctccaggtac ggagtttatg
1201 gccaaattga ccaaaaactt acaatatttt attcacgaca agatttctaa cgattccaaa
1261 tggagggaag tgcaaatcat attttctggc catgaagttc caggtgaagg tgaacacaag
1321 atcatgaact ttataaggca tttaaaatcc caaaaggatt tcaaccagaa tacgagacat
1381 tgtatttacg gtcttgacgc agatttgatt atgctgggtt tgtctactca tgggccacat
1441 tttgcgttat tgagagaaga agtgacattt ggtagaagaa atagtgaaaa aaaatcgctt
1501 gaacatcaaa atttctactt attacatctt tctttattaa gagaatacat ggagttggaa
1561 ttcaaagaaa ttgccgatga aatgcaattt gaatacaatt ttgaacgtat tttggatgat
1621 tttattcttg tcatgttcgt cattggtaat gatttcttgc ccaatttgcc agatttgcac
1681 cttaacaaag gagcatttcc cgttttgtta caaacgttca aagaagctct tttacatact
1741 gatggctaca ttaatgaaca tggtaaaata aatttaaaga gattaggtgt ctggttaaat
1801 tatctgtctc aatttgagtt attaaatttc gaaaaggatg atatagacgt tgagtggttc
1861 aacaagcaat tagagaatat ttctttggag ggtgaaagga aaagacagag ggttggtaaa
1921 aaattactgg taaaacaaca gaagaaatta attggaagta taaaaccatg gttgatggag
1981 caattacagg aaaaattatc gcctgattta ccagatgaag aaattccaac tttagagtta
2041 cctaaggact tagacatgaa agatcattta gaatttttaa aagaattcgc ttttgatttg
2101 ggtcttttta taacgcattc caaatccaaa ggtagttatt cgctaaaaat ggatcttgat
2161 tctattaatc ctgatgaaac agaagaagaa tttcaaaatc gtgttaattc tatcaggaaa
2221 acaataaaaa aatatcaaaa tgctatcatc gtggaggaca aagaagaatt ggaaactgaa
2281 aaaacgattt ataatgaaag gtttgaacgt tggaagcatg agtattatca cgacaagtta
2341 aaatttacga cagacagtga agaaaaagtg agagatcttg ctaaagacta cgttgaaggt
2401 ttacaatggg ttctatatta ttattataga ggatgtccat cttggtcgtg gtactatccg
2461 caccattatg caccaagaat ctccgactta gccaagggtt tagatcaaga cattgaattt
2521 gatttgagca aaccatttac tccattccag caactaatgg cagttttacc ggaaaggtcc
2581 aaaaatctga tacctcccgc ctttaggcca ttaatgtacg atgaacagtc gccaatccac
2641 gatttctatc ccgctgaggt tcaacttgat aaaaacggca agacagctga ttgggaagct
2701 gtggttttga tatcgtttgt agatgaaaaa aggttgattg aggctatgca accttatttg
2761 cgcaagttat cacctgaaga aaaaacgaga aatcaatttg gcaaggactt gatatattcc
2821 tttaatcctc aagttgataa cctttataag agtccgttgg gcggcatttt ttctgatatt
2881 gaacacaatc attgtgtcga aaaagagtac atcaccatcc cattggacag ctccgagatt
2941 cggtatggtt tattacctaa tgctaaactc ggtgccgaaa tgctggcggg tttccccacg
3001 ttattgtctt taccatttac tagttcactg gagtacaatg agacaatggt tttccaacaa
3061 ccttctaaac aacaatcaat ggtcttacaa ataactgaca tatacaaaac gaataatgtt
3121 actttggagg acttttccaa gaggcattta aacaaagtga tttatacaag atggccatat
3181 ttaagagaat ccaaattggt ctctttaacg gatggtaaga ctatctatga atatcaggag
3241 tccaatgata agaaaaagtt cggattcata acgaagcctg cggaaaccca ggacaaaaaa
3301 cttttcaata gtttgaagaa ttcaatgcta aggatgtatg ctaaacagaa agctgttaaa
3361 ataggaccta tggaagccat tgctaccgtc tttccagtga ctggtttggt gagagactct
3421 gatggtggtt atattaagac ctttagccct accccagatt actatccatt gcaactggtt
3481 gttgaatctg ttgtcaacga ggatgaaaga tataaagaaa gaggacccat tcctattgaa
3541 gaggaatttc cattgaattc aaaagttatt ttcttaggtg attatgccta tggtggtgaa
3601 actactattg acggttacag cagtgaccgc agactaaaaa ttactgtaga aaagaagttt
3661 ttggatagtg agcccaccat cggcaaagaa aggttacaaa tggatcatca agccgttaaa
3721 tattatccgt cttatattgt gtccaagaac atgcacttac accccttgtt tttgtctaag
3781 attacttcca agttcatgat tactgacgct actgggaagc atatcaatgt tggtatcccg
3841 gttaagttcg aagctagaca ccaaaaggtt ttaggttacg cgaggaggaa ccctaggggc
3901 tgggaatact caaatttaac tctaaattta ctgaaagagt atagacaaac tttcccagat
3961 ttttttttca ggttgtccaa ggtaggtaat gatatcccag ttttggaaga tcttttcccc
4021 gatacttcca ctaaggatgc catgaattta ttagatggta tcaaacaatg gctaaagtat
4081 gtctcatcga agtttatcgc ggtatctttg gagtctgact ccttaactaa gacatcgatt
4141 gctgccgtgg aagatcatat catgaaatac gcagctaaca tcgaaggtca tgaaagaaaa
4201 cagttagcca aagttcctcg tgaggctgtt ttgaatccaa gatcatcatt tgcactctta
4261 cgtagtcaaa agttcgattt gggtgaccgt gttgtttata tccaagattc tggtaaggta
4321 ccaattttct caaagggtac agttgttggc tatactactc tcagttcatc attatcaatt
4381 caggtcttat ttgatcatga aatcgtggcc ggtaataatt ttggcggcag gttgcgcacg
4441 aatagaggct tagggcttga tgcctctttc ttattgaata ttactaacag gcagttcatt
4501 tatcactcca aggcttccaa aaaggctttg gaaaagaaaa agcaatctaa caataggaac
4561 aataatacca aaactgctca caagactcct tcaaagcaac aatctgaaga aaaactgaga
4621 aaagaaaggg cacatgattt attgaatttt atcaaaaagg ataccaatga aaagaattct
4681 gaaagtgtag acaacaagag catgggatcg caaaaagatt ccaaacccgc aaagaaagtt
4741 ttgttaaaaa gaccagctca gaaaagcagt gaaaacgtgc aagttgattt ggccaatttt
4801 gaaaaagcac cgcttgataa tccaactgtt gctggatcta ttttcaatgc cgttgcaaat
4861 caatattctg atggtatagg cagtaatttg aatatcccaa ctccacctca cccaatgaat
4921 gtggttgggg gtcctattcc tggagcgaat gatgttgcag atgttggttt gccgtacaat
4981 attcccccag gttttatgac gcatcctaat ggtcttcacc cattacaccc tcaccagatg
5041 ccttacccta atatgaatgg aatgtctatt ccgccaccag caccacatgg gtttggacaa
5101 ccgatttcct tcccacctcc acctcctatg acaaatgttt cagatcaagg aagtcgtatt
5161 gttgtcaatg aaaaggaaag ccaagatttg aaaaaattca ttaatggtaa acagcacagc
5221 aatggttcaa ctattggggg agaaacaaag aacagtagga aaggcgagat taaaccttct
5281 tctggcacaa actctactga atgtcaatcg ccaaagtcac aaagcaatgc tgctgaccgt
5341 gataataaaa aagacgaatc tacttagaac atacgactaa aaacgaagta tattcgaggt
5401 tactttaata gtatatctga gacctatata aagaggggta tttgtattta atcgttgatc
5461 ttgttaagaa aaagcttata acaaatgggg attgtcaaag ggtatttttt acacaaagct
5521 ttccgcatag ttatatatta tctcattttc aataatcctc ctgtagggtg tagctttgca
5581 ctttcttctc attcatctca ttttgcttag caaaccattt ttcttcaaag ccatttgatc
5641 tgtgacaccg tcccatcttg acccaggcat aatggcaaac ctgttctcag gtgctggctt
5701 atcataaagc ttgcggccca gtaaagatgt ttttacagtt ctttctttgt catgtgtaaa
5761 tgttattgca gggtcttcta tcgtcagact cgag
//