GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS OFA81MAC1 92 bp ds-DNA INV 16-MAR-1991
DEFINITION O.fallax micronuclear (81-MAC family, version A) DNA, region
SRRHGKH-a (partial).
ACCESSION M15836 M13033
KEYWORDS 81-MAC chromosome family; alternative DNA processing;
homolog of mitochondrial solute carriers.
SEGMENT 1 of 3
SOURCE O.fallax (subkaryonide 3.5) micronuclear DNA, region SRRHGKH-a,
clone L47-mic21.
ORGANISM Oxytricha fallax
Eukaryota; Animalia; Metazoa; Ciliophora; Polyhymenophora;
Spirotricha; Hypotrichida; Sporadotrichina; Oxytrichidae.
REFERENCE 1 (bases 1 to 92)
AUTHORS Herrick,G.
JOURNAL Unpublished (1987) Univ. of Utah, Salt Lake City, Utah 84132
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 92)
AUTHORS Herrick,G., Hunter,D., Williams,K. and Kotter,K.
TITLE Alternative processing during development of a macronuclear
chromosomal family in Oxytricha fallax
JOURNAL Genes Dev. 1, 1047-1058 (1987)
STANDARD full staff_entry
REFERENCE 3 (bases 1 to 92)
AUTHORS Herrick,G., Cartinhour,S.W., Williams,K.R. and Kotter,K.P.
TITLE Multiple sequence versions of the Oxytricha fallax 81-MAC alternate
processing family
JOURNAL J. Protozool. 34, 429-434 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [J. Protozool. 34,
429-434 (1987)] kindly provided
by G.Herrick, 12-DEC-1986.
This sequence is the first 92 bp of that referred to as SRRHGKH-a
in [J. Protozool. 34, 429-434 (1987)]. It also could be referred
to as mic-SR-a by the
conventions in [J. Protozool. 34, 429-434 (1987)]
The 81-MAC chromosome family is created by alternative processing
of the micronuclear DNA. The 81-MAC family consists of three sizes
of macronuclear chromosomes: 4.9 kb (MACI), 2.9 kb (MACII), and 1.6
kb (MACIII). Alternative processing results from alternative
choice of chromosome break/telomere-addition sites. The 1.6 kb
region in common between the three chromosomes bears a transcribed
open reading frame, the conceptual translation product of which is
homologous to solute carrier proteins from plants and metazoans.
There are three distinct micronuclear loci (sequence versions),vA,
vB, and vC. Alternative processing of each micronuclear version
independently gives rise to a I+II+III family of macronuclear
chromosomes. The open reading frame is conserved in all three
versions. Little is known about the structure of vB micronuclear
DNA (no clones), but vA and vC micronuclear DNAs bear
micronucleus-limited sequences called internal eliminated sequences
(IESs). vA and vC have small IESs in common, but in addition, vC
bears two large transposons, TBE1-1 and -2, which also are IESs.
IESs are precisely excised, leaving one short flanking direct
repeat in macronuclear DNA.
Only one copy of the tandem repeat (positions 56-69) is found in vB
and vC.
FEATURES Location/Qualifiers
repeat_region 56..62
/note="direct tandem repeat tgatata copy A"
repeat_region 63..69
/note="direct tandem repeat tgatata copy B"
BASE COUNT 39 a 6 c 15 g 32 t
ORIGIN
1 aaaaagcgag aggtattatt gaatgaataa tcaagagttt atcaaagatt tagaatgata
61 tatgatataa tgctttataa tgtactttat ca
//GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS OFA81MAC3 353 bp ds-DNA INV 16-MAR-1991
DEFINITION O.fallax micronuclear (81-MAC family, version A) DNA, region
mic-KH-a.
ACCESSION M13042
KEYWORDS 81-MAC chromosome family; alternative DNA processing;
homolog of mitochondrial solute carriers.
SEGMENT 3 of 3
SOURCE O.fallax (subkaryonide 3.5) micronuclear DNA, region mic-KH-a,
clone L47-mic21.
ORGANISM Oxytricha fallax
Eukaryota; Animalia; Metazoa; Ciliophora; Polyhymenophora;
Spirotricha; Hypotrichida; Sporadotrichina; Oxytrichidae.
REFERENCE 1 (bases 1 to 353)
AUTHORS Herrick,G.
JOURNAL Unpublished (1987) Univ. of Utah, Salt Lake City, Utah 84132
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 353)
AUTHORS Herrick,G., Cartinhour,S.W., Williams,K.R. and Kotter,K.P.
TITLE Multiple sequence versions of the Oxytricha fallax 81-MAC alternate
processing family
JOURNAL J. Protozool. 34, 429-434 (1987)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [J. Protozool. 34,
429-434 (1987)] kindly provided
by G.Herrick, 12-DEC-1986.
The 81-MAC chromosome family is created by alternative processing
of the micronuclear DNA. The 81-MAC family consists of three sizes
of macronuclear chromosomes: 4.9 kb (MACI), 2.9 kb (MACII), and 1.6
kb (MACIII). Alternative processing results from alternative
choice of chromosome break/telomere-addition sites. The 1.6 kb
region in common between the three chromosomes bears a transcribed
open reading frame, the conceptual translation product of which is
homologous to solute carrier proteins from plants and metazoans.
There are three distinct micronuclear loci (sequence versions),vA,
vB, and vC. Alternative processing of each micronuclear version
independently gives rise to a I+II+III family of macronuclear
chromosomes. The open reading frame is conserved in all three
versions. Little is known about the structure of vB micronuclear
DNA (no clones), but vA and vC micronuclear DNAs bear
micronucleus-limited sequences called internal eliminated sequences
(IESs). vA and vC have small IESs in common, but in addition, vC
bears two large transposons, TBE1-1 and -2, which also are IESs.
IESs are precisely excised, leaving one short flanking direct
repeat in macronuclear DNA.
When the IES is excised the 5' imperfectly duplicated sequence
'atta' remains in the macronuclear DNA. The sequence of the
homologous macronuclear DNA can be found in a separate entry:
M15835.
FEATURES Location/Qualifiers
repeat_region 138..141
/note="5' imperfectly duplicated sequence"
iDNA 142..210
/note="IES"
repeat_region 207..210
/note="3' imperfectly duplicated sequence"
BASE COUNT 125 a 56 c 27 g 145 t
ORIGIN 5 bp upstream of KpnI site; about 0.9 kb after segment 2.
1 ggtaccttct tctccagtac tcaactaaaa ataaatttta taaatcgatg attcgatatt
61 ttattgataa atttaccttc catttaagta ggcatctttc ttgattgctt attttaaaat
121 aattttaata actttatatt attgtaatca cattaagatt tatagtataa tttcaaagaa
181 tcattttaat ttccttatat tcaagcaata attatgttta ttacaaatta tttcaattaa
241 gttcattcaa aaataaatct ctgccacctt taaaatctat atttaggtta actcaagtct
301 tcaaacaaca cttctctgtg aagaatcact tcttaaaaca ccagttttct act
//GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS OFA81MCA1 846 bp ds-DNA INV 16-MAR-1991
DEFINITION O.fallax micronuclear (81-MAC family, version C) DNA, region
mic-BSRRHG-c.
ACCESSION M13035 M13029 M13036
KEYWORDS 81-MAC chromosome family; TBE1 telomere bearing element;
alternative DNA processing;
homolog of mitochondrial solute carriers; transposon.
SEGMENT 1 of 3
SOURCE O.fallax (subkaryonide 3.5) micronuclear DNA, regions SRRHG-c,
mic-RR-c and mic-Rg-c, clones L47-mic[10,20].
ORGANISM Oxytricha fallax
Eukaryota; Animalia; Metazoa; Ciliophora; Polyhymenophora;
Spirotricha; Hypotrichida; Sporadotrichina; Oxytrichidae.
REFERENCE 1 (sites)
AUTHORS Herrick,G., Cartinhour,S., Dawson,D., Ang,D., Sheets,R., Lee,A. and
Williams,K.
TITLE Mobile elements bounded by C-4-A-4 telomeric repeats in Oxytricha
fallax
JOURNAL Cell 43, 759-768 (1985)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 846)
AUTHORS Herrick,G.
JOURNAL Unpublished (1987) Univ. of Utah, Salt Lake City, Utah 84132
STANDARD full staff_entry
REFERENCE 3 (bases 1 to 846)
AUTHORS Herrick,G., Cartinhour,S.W., Williams,K.R. and Kotter,K.P.
TITLE Multiple sequence versions of the Oxytricha fallax 81-MAC alternate
processing family
JOURNAL J. Protozool. 34, 429-434 (1987)
STANDARD full staff_review
COMMENT
[Cell 43, 759-768 (1985)] sites; telomere-bearing element
description.
Draft entry and computer-readable sequence for [J. Protozool. 34,
429-434 (1987)] kindly provided
by G.Herrick, 12-DEC-1986.
This sequence would be named 'mic-SRRg-c' by the conventions in
[J. Protozool. 34, 429-434 (1987)].
Bases 1-494 come from region SRRHG-c, 372-617 from mic-RR-c, and
612-846 from mic-Rg-c as referred to in [J. Protozool. 34, 429-434
(1987)].
The 81-MAC chromosome family is created by alternative processing
of the micronuclear DNA. The 81-MAC family consists of three sizes
of macronuclear chromosomes: 4.9 kb (MACI), 2.9 kb (MACII), and 1.6
kb (MACIII). Alternative processing results from alternative
choice of chromosome break/telomere-addition sites. The 1.6 kb
region in common between the three chromosomes bears a transcribed
open reading frame, the conceptual translation product of which is
homologous to solute carrier proteins from plants and metazoans.
There are three distinct micronuclear loci (sequence versions),vA,
vB, and vC. Alternative processing of each micronuclear version
independently gives rise to a I+II+III family of macronuclear
chromosomes. The open reading frame is conserved in all three
versions. Little is known about the structure of vB micronuclear
DNA (no clones), but vA and vC micronuclear DNAs bear
micronucleus-limited sequences called internal eliminated sequences
(IESs). vA and vC have small IESs in common, but in addition, vC
bears two large transposons, TBE1-1 and -2, which also are IESs.
IESs are precisely excised, leaving one short flanking direct
repeat in macronuclear DNA.
When TBE1-1 is excised one flanking 'aat' probably remains in
macronuclear DNA, as judged from oligomer hybridization
experiments.
FEATURES Location/Qualifiers
repeat_region 490..494
/note="5' IES duplicated sequence"
iDNA 495..566
/note="IES"
repeat_region 562..566
/note="3' IES duplicated sequence"
repeat_region 715..717
/note="5' TBE1-1 duplicated insertion target sequence"
repeat_region 718..734
/note="telomere sequence of TBE1-1"
repeat_region 718..795
/note="5' TBE1-1 inverted terminal repeat"
transposon 718..>846
/note="TBE1-1 insertion element"
BASE COUNT 293 a 100 c 155 g 298 t
ORIGIN 86 bp upstream of SphI site.
1 agagacggag gaatgattga atgtgcaaaa tatatcttta agaatgaaca tgggtttatg
61 ggattttgga gagggttctc agcatgcagt gcaagagcag tatttgctaa ttctttcatg
121 tttgtggctt atgaatatgc ttagaaaaaa gcgagaggta ttattgaatg aatgatcgtg
181 gatttatcaa agtttttgaa tgatataatg ctttataatg tactttatca aagtaactta
241 agactgtgat attaatatga actaagatta tatataaatt taatattttt aaataggttt
301 aaataacaaa taaatctcta ctttaacaca aagcatgtga taatacttta tgttagagac
361 aatttatttc tgaattctca gataattgcg agattttctt ttcctgaagg atgagcagct
421 cccatacctc cagtagctgt agtataagta gcaactaatt ttttattgaa ggcatctgtg
481 tatggatcat gaatcataac gatttataaa attttggaaa aaatcataat ctaaaatttc
541 tgcttcatta taataagtta ttgaatatcg taatcgatac cactttgata gtggaatctc
601 tgtggttgcc agaattcttg atcatagtag ttttcgttat agtagtctac caagaattga
661 gaaagataac aaatcaagaa caatctgagg aagtaggctt cacctcctgc atagaatcaa
721 aaccccaaaa ccccttaagt agatggttta gtgtattgat ttgtagagaa tttgttaggg
781 gttggggtta ttaatagttt ttaatgtgga aatttatagt aaatgtattt aatttaatca
841 ctcaaa
//GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS OFA81MCA2 1232 bp ds-DNA INV 16-MAR-1991
DEFINITION O.fallax micronuclear (81-MAC family, version C) DNA, regions
SRRHG-c (partial), mic-gH-c and GKH-c (partial).
ACCESSION M13037 M13029 M13038 N00056
KEYWORDS 81-MAC chromosome family; TBE1 telomere bearing element;
alternative DNA processing;
homolog of mitochondrial solute carriers; transposon.
SEGMENT 2 of 3
SOURCE O.fallax (subkaryonide 3.5) micronuclear DNA, regions mic-gH-c and
SRRHG-c, clones L47-mic[2,8,10,20,22,26].
ORGANISM Oxytricha fallax
Eukaryota; Animalia; Metazoa; Ciliophora; Polyhymenophora;
Spirotricha; Hypotrichida; Sporadotrichina; Oxytrichidae.
REFERENCE 1 (sites)
AUTHORS Herrick,G., Cartinhour,S., Dawson,D., Ang,D., Sheets,R., Lee,A. and
Williams,K.
TITLE Mobile elements bounded by C-4-A-4 telomeric repeats in Oxytricha
fallax
JOURNAL Cell 43, 759-768 (1985)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1232)
AUTHORS Herrick,G.
JOURNAL Unpublished (1987) Univ. of Utah, Salt Lake City, Utah 84132
STANDARD full staff_entry
REFERENCE 3 (bases 1 to 827)
AUTHORS Herrick,G., Cartinhour,S.W., Williams,K.R. and Kotter,K.P.
TITLE Multiple sequence versions of the Oxytricha fallax 81-MAC alternate
processing family
JOURNAL J. Protozool. 34, 429-434 (1987)
STANDARD full staff_review
REFERENCE 4 (bases 828 to 1232)
AUTHORS Hunter,D.J., Williams,K., Cartinhour,S. and Herrick,G.
TITLE Precise excision of telomere-bearing transposons during Oxytricha
fallax macronuclear development
JOURNAL Genes Dev. 3, 2101-2112 (1989)
STANDARD full staff_entry
COMMENT
[Cell 43, 759-768 (1985)] sites; telomere-bearing element
description.
Draft entry and computer-readable sequence for [J. Protozool. 34,
429-434 (1987)] kindly provided
by G.Herrick, 12-DEC-1986.
Bases 1-398 are from region mic-gH-c and 118-827 from SRRHG-c as
referred to in [J. Protozool. 34, 429-434 (1987)].
This sequence would be named 'mic-gHGh-c' by the convention in [J.
Protozool. 34, 429-434 (1987)].
The 81-MAC chromosome family is created by alternative processing
of the micronuclear DNA. The 81-MAC family consists of three sizes
of macronuclear chromosomes: 4.9 kb (MACI), 2.9 kb (MACII), and 1.6
kb (MACIII). Alternative processing results from alternative
choice of chromosome break/telomere-addition sites. The 1.6 kb
region in common between the three chromosomes bears a transcribed
open reading frame, the conceptual translation product of which is
homologous to solute carrier proteins from plants and metazoans.
There are three distinct micronuclear loci (sequence versions),vA,
vB, and vC. Alternative processing of each micronuclear version
independently gives rise to a I+II+III family of macronuclear
chromosomes. The open reading frame is conserved in all three
versions. Little is known about the structure of vB micronuclear
DNA (no clones), but vA and vC micronuclear DNAs bear
micronucleus-limited sequences called internal eliminated sequences
(IESs). vA and vC have small IESs in common, but in addition, vC
bears two large transposons, TBE1-1 and -2, which also are IESs.
IESs are precisely excised, leaving one short flanking direct
repeat in macronuclear DNA.
When TBE1-1 is excised one flanking 'aat' probably remains in
macronuclear DNA, as judged from oligomer hybridization
experiments. When TBE1-2 is excised one flanking 'aat' remains in
macronuclear DNA; the sequence of the resulting macronuclear DNA
can be found in a separate entry, accession number M25391.
FEATURES Location/Qualifiers
transposon <1..114
/note="TBE1-1 insertion element"
repeat_region 38..114
/note="3' TBE1-1 inverted terminal repeat"
repeat_region 98..114
/note="telomere sequence of TBE1-1"
repeat_region 115..117
/note="3' TBE1-1 duplicated insertion target sequence"
repeat_region 1048..1050
/note="5' TBE1-2 duplicated insertion target sequence"
repeat_region 1051..1067
/note="telomere sequence of TBE1-2"
repeat_region 1051..1128
/note="5' TBE1-2 inverted terminal repeat"
transposon 1051..>1232
/note="TBE1-2 insertion element"
BASE COUNT 379 a 232 c 224 g 394 t 3 others
ORIGIN About 3.2 kb after segment 1.
1 agaccccgga tagcttgtaa tttttgtctc gcatttaatt aataacccaa cccctaacaa
61 attccctaca aatcaataca ctaaaccatc tacttaaggg gttttggggt tttgaatgat
121 ccaaagttag acatccactt tgagttacac tcgtacttta tgatcttgtt gaagcaatca
181 atcatgccgt tatatggcat ttgaccgttt ggtagtggtc tcatggtgtg tagtcttgtt
241 ctgatcatat cgaaaggcat acttacagca gttcctatag caacagctac ggcagtaccc
301 cacaatctat taatccaatg aggaccaaag aagaagtagg agttttcctt gcaccaatcg
361 tagatgtttg tcattgatga acaaatagct gcaagcttaa aaccgttggc accagcacct
421 ctgaagagag caccttcttc agcaactttg gcaagtcctt aaattgtatt tgagtaattt
481 cttctggcag cttgtggata aagctcatca acttgcattc tattgtagac gatatcgatt
541 ggatttgtca ctacaccagc aataaatcct ccgagtactc ctgctgctac caagaagtct
601 ggacgagcaa ctcttctggg atctttattt accttatcgt agaaataacc gaaggctgtt
661 actctggcag tagtgtaaca aacagttctg aagaagaatg tgtcgaaact ataccaatat
721 aaattagcta aatttattgc aattcctcaa ttataatgtt gagagagaac tttatataag
781 ccaaattttg tttatacact tacgcagaat agaatttttt gagtccacct cctgctgcat
841 aaatctcttc cataatttag aatggatacc aacccttttg ataaccaagg cctgagaagg
901 tcttgccctc ttacagcatt tgagatctga ttctaaccat atcgagtggt taagtctata
961 ttacatttag aatatgatta atcattgcta ataagataga aaatgtgcta tagaatacta
1021 acttacagca gcatgagtta tgagagcaat caaaacccca aaacccctta agtagatggt
1081 ttagtgtatt gatttgtagg gaatttgtta ggggttgggg ttattaatag gttttaatgt
1141 gaaatttaaa gtatatmtat ttaactttaa tcactcaaaa tmtacttttg gatcgtgtgg
1201 gagnggtctg aaggtttatc ttacttaacc ac
//GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS OFA81MCA3 591 bp ds-DNA INV 16-MAR-1991
DEFINITION O.fallax micronuclear (81-MAC family, version C) DNA, regions
mic-rK-c, GKH-c (partial), and mic-KH-c.
ACCESSION M13039 M13030 M13040
KEYWORDS 81-MAC chromosome family; TBE1 telomere bearing element;
alternative DNA processing;
homolog of mitochondrial solute carriers; transposon.
SEGMENT 3 of 3
SOURCE O.fallax (subkaryonide 3.5) micronuclear DNA, regions mic-rK-c,
GKH-c and mic-KH-c, clone L47-mic22.
ORGANISM Oxytricha fallax
Eukaryota; Animalia; Metazoa; Ciliophora; Polyhymenophora;
Spirotricha; Hypotrichida; Sporadotrichina; Oxytrichidae.
REFERENCE 1 (sites)
AUTHORS Herrick,G., Cartinhour,S., Dawson,D., Ang,D., Sheets,R., Lee,A. and
Williams,K.
TITLE Mobile elements bounded by C-4-A-4 telomeric repeats in Oxytricha
fallax
JOURNAL Cell 43, 759-768 (1985)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 591)
AUTHORS Herrick,G.
JOURNAL Unpublished (1987) Univ. of Utah, Salt Lake City, Utah 84132
STANDARD full staff_entry
REFERENCE 3 (bases 1 to 591)
AUTHORS Herrick,G., Hunter,D., Williams,K. and Kotter,K.
TITLE Alternative processing during development of a macronuclear
chromosomal family in Oxytricha fallax
JOURNAL Genes Dev. 1, 1047-1058 (1987)
STANDARD full staff_entry
REFERENCE 4 (bases 1 to 591)
AUTHORS Herrick,G., Cartinhour,S.W., Williams,K.R. and Kotter,K.P.
TITLE Multiple sequence versions of the Oxytricha fallax 81-MAC alternate
processing family
JOURNAL J. Protozool. 34, 429-434 (1987)
STANDARD full staff_review
COMMENT
[Cell 43, 759-768 (1985)] sites; telomere-bearing element
description.
Draft entry and computer-readable sequence for [J. Protozool. 34,
429-434 (1987)] kindly provided
by G.Herrick, 12-DEC-1986.
Bases 1-237 are from region mic-rK-c; 194-372 and 443-591 from
GKH-c; and 232-591 from mic-KH-c as referred to in [J. Protozool.
34, 429-434 (1987)].
This sequence would be named 'mic-rKH-c' by the conventions in [J.
Protozool. 34, 429-434 (1987)].
The 81-MAC chromosome family is created by alternative processing
of the micronuclear DNA. The 81-MAC family consists of three sizes
of macronuclear chromosomes: 4.9 kb (MACI), 2.9 kb (MACII), and 1.6
kb (MACIII). Alternative processing results from alternative
choice of chromosome break/telomere-addition sites. The 1.6 kb
region in common between the three chromosomes bears a transcribed
open reading frame, the conceptual translation product of which is
homologous to solute carrier proteins from plants and metazoans.
There are three distinct micronuclear loci (sequence versions),vA,
vB, and vC. Alternative processing of each micronuclear version
independently gives rise to a I+II+III family of macronuclear
chromosomes. The open reading frame is conserved in all three
versions. Little is known about the structure of vB micronuclear
DNA (no clones), but vA and vC micronuclear DNAs bear
micronucleus-limited sequences called internal eliminated sequences
(IESs). vA and vC have small IESs in common, but in addition, vC
bears two large transposons, TBE1-1 and -2, which also are IESs.
IESs are precisely excised, leaving one short flanking direct
repeat in macronuclear DNA.
When the short IES is excised the 5' imperfectly duplicated
sequence 'atta' remains in the macronuclear DNA. Similarly, when
TBE1-2 is excised one flanking 'aat' remains in macronuclear DNA.
The sequence of the homologous macronuclear DNA can be found in a
separate entry, accession number M25391.
FEATURES Location/Qualifiers
transposon <1..190
/note="TBE1-2 insertion element"
repeat_region 114..190
/note="3' TBE1-2 inverted terminal repeat"
repeat_region 174..190
/note="telomere sequence of TBE1-2"
repeat_region 191..193
/note="3' TBE1-2 duplicated insertion target sequence"
repeat_region 369..372
/note="5' IES imperfectly duplicated sequence"
iDNA 373..442
/note="IES"
repeat_region 439..442
/note="3' IES imperfectly duplicated sequence"
BASE COUNT 209 a 106 c 55 g 221 t
ORIGIN About 3 kb after segment 2.
1 ggtttgactt agtcactata tatatcacat ccatatcgca gtttaaacac taaatctata
61 tactcttcat cataaataga ccccaatagc ttgtaatttt tgtctcgcat ttaattaata
121 acccaacccc taacaaattc cctacaaatc aatacactaa accatctact taaggggttt
181 tggggttttg aatgacatta gcagcagcaa atctttcata gttcatgcgt tggtaccttc
241 ttctccagta ctcaactaaa acgaaatttt agaaatcaat gattcgatat tttattgata
301 aatttacctt ccatttaagt aggcatcttt cttgattgct tattttaaaa taattataat
361 aactttatat tattgcaata acattaagat ttaatagttt ataatgacga tttcatttta
421 atttcattat attcaagcaa taattatgtt tattacaaat tatttcaatt aagttcatta
481 aaaaacatta atctctctac caatttaaaa atttatatgt aagttaactc aagtcttcaa
541 acaacacttc tctgtgaaga atcacttctt aaaacaccag tcttctacta a
//