GenBank-Updates@genbank.bio.net (03/16/91)
LOCUS HUMPROFILE 2930 bp ss-mRNA PRI 16-MAR-1991
DEFINITION Human profilaggrin mRNA, 3' end.
ACCESSION M60502
KEYWORDS profilaggrin.
SOURCE Human, cDNA to mRNA, clone lambga-HF223.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2930)
AUTHORS Gan,S.-Q., McBride,W.O., Idler,W.W., Markova,N. and Steinert,P.M.
TITLE Organization, structure, and polymorphisms of the human
profilaggrin gene
JOURNAL Biochemistry 29, 9432-9440 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 1..2394
/product="profilaggrin"
/gene="profilaggrin"
/codon_start=1
/partial
polyA_signal 2909..2914
/gene="profilaggrin"
/partial
polyA_site 2930..2930
/gene="profilaggrin"
/partial
BASE COUNT 864 a 715 c 739 g 612 t
ORIGIN
1 ggccactctg cagacagctc cagacaatca ggcactcgtc acacagagtc ttcctctcgt
61 ggacaggctg cgtcatccca tgaacaggca agatcaagtg caggagaaag acatggatcc
121 caccaccagc agtcagcaga cagctccaga cacgcaggca ttgggcacgg acaagcttca
181 tctgcagtca gagacagtgg acaccgaggg tacagaggta gtcaggccac tgacagtgag
241 ggacattcag aagactcaga cacacagtca gtgtcagcac agggacaagc tgggccccat
301 cagcagagcc accaagagtc cgcacgtggc cagtcagggg aaagctctgg acgttcaggg
361 tctttcctct accaggtgag cactcatgaa cagtctgagt ccacccatgg acagtctgtg
421 cccagcactg gaggaagaca aggatcccac catgatcagg cacaagacag ctccaggcac
481 tcagcatccc aagagggtca ggacaccatt cgtggacacc cggggccaag cagaggagga
541 agacaggggt cccaccacga gcaatcggta gataggtctg gacactcagg gtcccatcac
601 agccacacca catcccaggg aaggtctgat gcctcccgtg ggcagtcagg atccagaagt
661 gcaagcagac aaacacatga ccaggaacaa tcaggagacg gctctaggca ctcagggtcg
721 cgtcatcagg aagcttcctc ttgggccgac agctctagac actcacaggc agtccaggga
781 caatcagagg ggtccaggac aagcaggcgc cagggatcca gtgttagcca ggacagtgac
841 agtcagggac actcagaaga ctctgagagg cggtctgggt ctgcttccag aaaccatcgt
901 ggatctgctc aggagcagtc aagagatggc tccagacacc ccaggtccca tcacgaagac
961 agagccggtc acggggactc tgcagagagc tccagacaat caggcactca tcatgcagag
1021 aattcctctg gtggacaggc tgcatcatcc catgaacagg caagatcaag tgcaggagag
1081 agacatggat cccactacca gcagtcagca gacagctcca gacactcagg cattgggcac
1141 ggacaagctt catctgcagt cagagacagt ggacaccgag ggtccagtgg tagtcaggcc
1201 agtgacaatg agggacattc agaagactca gacacacagt cagtgtcagc ccaccgacag
1261 gctgggcgcc atcacgagag ccaccaagag tccacacgtg gccggtcacg aggaaggtct
1321 ggacgttcag ggtctttcct ctaccaggtg agcactcatg aacagtctga gtctgcccat
1381 ggacgggctg ggcccagtac tggaggaaga caaggatccc gccacgagca ggcacgagac
1441 agctccaggc actcagcgtc ccaagagggt caggacacca ttcgtggaca cccggggtca
1501 aggagaggag gaagacaggg atcctaccac gagcaatcgg tagataggtc tggacactca
1561 gggtcccatc acagccacac cacatcccag ggaaggtctg atgcctccca tgggcagtca
1621 ggatccagaa gtgcaagcag agaaacacgt aatgaggaac agtcaggaga cggctccagg
1681 cactcagggt cgcgtcacca tgaagcttcc actcaggctg acagctctag acactcacag
1741 tccggccagg gtgaatcagc ggggtccagg agaagcaggc gccagggatc cagtgttagc
1801 caggacagtg acagtgaggc atacccagag gactctgaga ggcgatctga gtctgcttcc
1861 agaaaccatc atggatcttc tcgggagcag tcaagagatg gctccagaca ccccggatcc
1921 tctcaccgcg atacagccag tcatgtacag tcttcacctg tacagtcaga ctctagtacc
1981 gctaaggaac atggtcactt tagtagtctt tcacaagatt ctgcgtatca ctcaggaata
2041 cagtcacgtg gcagtcctca cagttctagt tcttatcatt atcaatctga gggcactgaa
2101 aggcaaaaag gtcaatcagg tttagtttgg agacatggca gctatggtag tgcagattat
2161 gattatggtg aatccgggtt tagacactct cagcacggaa gtgttagtta caattccaat
2221 cctgttcttt tcaaggaaag atctgatatc tgtaaagcaa gtgcgtttgg taaagatcat
2281 ccaaggtatt atgcaacgta tattaataag gacccaggtt tatgtggcca ttctagtgat
2341 atatcgaaac aactgggatt tagtcagtca cagagatact attactatga gtaagaaatt
2401 aatggcaaag gaattaatcc aagaatagaa gaatgaagca agttcacttt caatcaagaa
2461 acttcataat actttcaggg aagttatctt ttcctgtcaa tctgtttaaa atatgctata
2521 gtatttcatt agtttggtgg taacttattt ttattgtgta atgatcttta aacgctatat
2581 ttcagaaata ttaaatggaa gaaatcaata tcatggagag ctaactttag aaaactagct
2641 ggagtatttt aggagattct gggtcaagta atgttttatg tttttgaaag tttaagtttt
2701 agacactccc caaatttcta aattaatctt tttcagaaat atcgaaggag ccaaaaatat
2761 aaaacagttc tgatatccaa agtggctata tcaacatcag ggctagcaca tctttctcta
2821 ttatccttct attggaattc tagtattctg tattcaaaaa atcatcttgg acataattaa
2881 tattttagta agctgcatct aaattaaaaa taaactattc atcatataat
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