GenBank-Updates@genbank.bio.net (03/19/91)
LOCUS RABBCAS 11174 bp ds-DNA MAM 19-MAR-1991
DEFINITION O.cuniculus beta-casein gene, complete cds.
ACCESSION M33582
KEYWORDS beta-casein.
SOURCE O.cuniculus liver DNA.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 11174)
AUTHORS Thepot,D., Devinoy,E., Fontaine,M.L. and Houdebine,L.M.
TITLE Structure of the gene encoding rabbit beta-casein
JOURNAL Gene 97, 301-306 (1991)
STANDARD simple staff_entry
COMMENT Draft entry and computer readable sequence for [Gene (1990) In
press] kindly submitted
by E.Devinoy, 05-APR-1990.
FEATURES Location/Qualifiers
CDS join(3508..3558,4097..4123,4233..4259,5280..5300,
5396..5440,6974..7483,8417..8422)
/note="beta-casein"
/codon_start=3508
prim_transcript 446..9875
/note="beta-casein mRNA and introns"
exon 3508..3558
/note="beta-casein, exon 2 (first expressed exon)"
intron 3559..4096
/note="beta-casein intron A"
exon 4097..4123
/note="beta-casein, exon 3"
intron 4124..4232
/note="beta-casein intron B"
exon 4233..4259
/note="beta-casein, exon 4"
intron 4260..5279
/note="beta-casein intron C"
exon 5280..5300
/note="beta-casein, exon 5"
intron 5301..5395
/note="beta-casein intron D"
exon 5396..5440
/note="beta-casein, exon 6"
intron 5441..6973
/note="beta-casein intron E"
exon 6974..7483
/note="beta-casein, exon 7"
intron 7484..8416
/note="beta-casein intron F"
exon 8417..8422
/note="beta-casein, exon 8"
BASE COUNT 3634 a 2051 c 2018 g 3448 t 23 others
ORIGIN
1 actagttgct ttgttaattt ctccactgtg acataaagga ctgttcaggt tatcatgaag
61 tcatggtctt tgtgagcccc tgtgtatcgt tggtgttcat atagaatttc cctacagttg
121 agatctttag gcctccctag acccaaaaga aacctaatag tgctcacatt agtatcttgg
181 agactaggct ggagcaccac tcttctccag ccattgtgtt tattattggg caattcattt
241 cctggacaca tttcctttat aggcctatga attactgcct tgtctcaatg ctccccagaa
301 tttctgggga aagataatga gtagaaatca ttttctaatc atatggagtt cttggaattg
361 aaactcaaaa tcgatttttt ttttcaaacc acaaaattag catgtcatta aatgcagtat
421 ataagcatcc ccaaaagcag agaacatcat ccacccagct tcattttcac ttcttgtcct
481 ccaccttgga ataaaggtaa gaattctagg tatgaatttc atttactcac ccaaccttta
541 tttcagaata tgattaaaat acagtttttg aaataaagtt acctgagata gtactaaaat
601 tatttttaac acttagaaaa aataggatgc ctagaaatat ttaacaaaac atacaaagat
661 tatataagcc ttgtaaatcc tatgcaatgt agtaactaat ttaatatgtg tagcaaaact
721 agctaatact taatattaag atgatatcta tttcttgaat taaatgtctt caaatttaca
781 taacatatta aaaccataaa acaaatatat ttaaattagc ttgagaagat gaataattat
841 tgggaaagtt ttttttacca atatgtagca tgctgagtca agaaacagat ggagggagtg
901 ggaacataca atatcctaaa tattcataaa ctttttagaa gaagagtgta ctcattaaag
961 ttaagttggc ctagactctc cagtttccca gtttatcatc tagtttataa tatttcaaaa
1021 taatcttata atggagacat ggagatacag agttaagctg aaaaaatcaa attattctac
1081 attttaagaa aattctacat gtgacaaaga tgtcttgcaa acaaaacaca aaggaaatag
1141 atgatttgaa aacagtagat gtataccagt ctataataaa attcttgctt aaaaactagt
1201 atacaaaata ctacgtgtaa gagatagaaa atgcagtggg attcttctta ctttacttgt
1261 ctattgcctt gtgttacatt tttttgaact ctttacaaga aaaactcctt tggaaattta
1321 tggtgtctca ggcaaggtaa aattaataaa taattataaa ccattcataa gaaaaacaaa
1381 aaattatttt cacaaatgga attatttcaa ccttcaacta ttggaaagga tatttttctt
1441 ttttttatga ttcattttac ttatcagaag ggcagagttt cagagagaga ggaagggaaa
1501 gacacagaga gaggtcttct ttctgttggt tcactcccca aatagctaca atggccaggg
1561 ttgggccagg ccgaagccag gaatcaagag cttctcctgg gtctccaatg tgggtgcagg
1621 ggtccaagca cttggacctt cctccactgc tttcccaggg cattagcatg gagctggatt
1681 ggaagtggag cagtggggac ttagacctgc atccatgtgg gatgcccatg ctgcatgtag
1741 aggcttaacc caccatgcca cagcactggg cccaggagat gacagttttc agaagcagaa
1801 ctttattctg agaactgttt gaatttcaga aatttagttt aaaaatatga aaatgaagat
1861 cgagtgtcaa atattattat ggcataaaaa ttaattttta aaataaatga tttaaaatgc
1921 aagaaaaagg aaggatattt ggcttagtgg ttaaagtgct ccttaggata tctgtctcca
1981 tgttagagtg cctggctttg agtcctaact ctgctccaac tccagcttcc tgctaatgca
2041 cagcctgaga ggcaacaggt tggatacctg tcacccaggt gggaggcctg aagtgagttc
2101 acagctcttg aatttgttct gatccagccc cagcctttgc tggcatttgg ggagtgatcc
2161 aacagatagg agttctctga ctgcctttct gtcttgtgta tgtctctctg tctttcagat
2221 aaaaaaaaaa ttttaaaaat gcaacaagaa aatcatagag gtcatttagt atattttgat
2281 caaaagtatt aacatatatt tcataagagg tagcttgggg ttagagagta ggcaagagga
2341 agtagccctt tgtaagtcat caagggatca gtgtgcattt taatagcaag agaaggccag
2401 cgctggggct cactaggcta atcctccgnc cttgcggcac tggcacaccg ggttctagtc
2461 ccggtcgggg cgccggattc tgtcctggtt gcccctcttc caggccagct ctctgctgtg
2521 gccagggagt gcagtggagg atggcccagc tccttgggcc ctgcacccca tgggagacca
2581 ggagaagcac ctggctcctg ccttcggatc agcgcggtgc ggctgcagcc attggagggt
2641 gaaccaacgg caaaggaaga cctttctctc tgtctctctc tctctcactg tccactctgc
2701 ctgtcaaaaa aataaaataa aaaacccaaa gctctacccg gctcaagggt gaggaaacaa
2761 aaatagcaag agaaacaacc tggagagtta tctctaaaat cacatggcat aatgagaaga
2821 gacatgattt ggtgtatggg gaggaagact acacagtggg gacagatgga gaaaactcaa
2881 acctatcatc taaaaaatca tctggagaat gaagcaaata aaggaaacac caaatgaaaa
2941 ttttagtttc attgaaaatg aaaagatcaa tttcaactag atatgcatgg caactgtttg
3001 gcagaaaaaa tcaaaataaa gggtcaatta taaattgtat gacttttctt gatcagttac
3061 ctgttgtaga attgagtctc gtttaggacg aaaatcttat tattttgctc attgctgcat
3121 tcctagtacc tggacactga caatgaaaga tgctaaataa atatttttga atatatgaat
3181 caatacatat ttctgtaaat attgataact ttatcccttt caaaaagtaa agcatggtag
3241 tgtgagagag agaaaaccag aagcatggag gagagtagtg aaatttgaat tttatacgca
3301 agcatcagga gacagggaag attttgaatt tgatcatctg acaaaacttc tttacttttt
3361 tactgtgaag tgcaagcatt tttactgcat tatcttggat gtcttttaaa ggaacactag
3421 ctctactcaa gtaaaaacat tgacctgatt gactaattga ttgactgatt aattctcttg
3481 tctctccatt cacaggactt ggcagtcatg aaggtcctca ttctcgcctg cctggtggct
3541 ctcgctcttg caagggaggt atgtgcaaaa gaaagttctc aataacgaaa atacagggaa
3601 ctatgtaccc gcttacaaac cacatcgcca acagtagcat acaagcaacg gaggttttct
3661 gcagaacttg cttggtttcc atgaaagtca actacgttca accattgtct caacagtttc
3721 ttgtaagccc caaaactcag ataaatgctt tctgtaaact gctgccagtc ctaaagagca
3781 aacaaacata tcaataaaca gcaacaacga tcagcaacaa aacaaaacac aagaaaaaga
3841 gagaaacaga aaagcagcaa gaaaatgtaa tatacacata caattgcaag tatgggcacc
3901 ccctataaat atatcttatt acagtggaaa taaaagactt taaagcaata tttcaagttt
3961 tttgaaaggc acataatatg tttttatttc tcaaatttgt gaaagaattt tatggagcta
4021 aaaattcact agaaaacaca tttaatcatg aattagctat agaaactgaa aaggtttttt
4081 ttttttcctt tttcagaagg aacaactcag tgttcccaca gaggtaagaa ttttttttct
4141 ccagagaaaa tattccagcc ataaagcagt aacattctct gaaatggctc ttagctggtt
4201 gctgatcttt tttccctatt ttttttttac aggctgtagg aagtgtttcc agcagcgagg
4261 taagacaaac tttttttcag aggcaatttc tcttttttag aacagtgaat cagagtacca
4321 tatgtgtctt acattacatc acagcagtta cacagatgtc atgttctgac atgtaagttc
4381 tgatataaat tccctttata tatgtttaca atcagaataa atgctgggga gtcactattc
4441 tagatctttc tatgtaggct tactacttca gttgtgtcag tttgccaaca cctcatccct
4501 tgttctatga gctgtatagt cctggtttct ggactccctc cgttctgacc tcatccacat
4561 gtaacattta tccagtcctt tctgtggatg agacattgac tagaaacagt gcacaaacgg
4621 aaaaaatcca gatgtcatta caatacagag cctgcgatgc accaacaggc agatatgcaa
4681 agggacataa tttgtaatta gaattgtcac tttagtaaac aagaagcaat gagaaatctt
4741 cctgggagaa ccaagtagat atgtatcctt ccacaattct tttttggtat gccatcatca
4801 gaacaatgtc ttttcacaaa atccataaga tccattgagg aggtatttat ttcctataat
4861 tcattggaag ccttacatat aagtaaactg tattactatt attttgcttc tattgttatt
4921 taaatgtatt ttcaatggca attttttttt tagaatcaca ttggatgttg gaaatcattt
4981 gtcctcagag aaagcaatat gattttagag agaactcagc ggcaattaaa tacctctttt
5041 tgtactagtt tcactagctt tcgttcacct cttggttgta ttgatctcac tttcttttat
5101 acaagacact tatgtagaat actataaatg aaaatttcaa caatcatccg gttatcaaac
5161 agaagcatgc acattaacct attaaatgcc ttcatttttt atttctattt aagtataagt
5221 gtttcagtaa aactatttag taaaactaaa tatgattttc tttttcattt tttctgaagg
5281 aaattacaca tatcaacaag gtaagacctc caaaattgtc attattttgc aagtttccca
5341 tgctagcttt tcaaaagtgg taacatttct ctctatatat atattttgtt tttagcagaa
5401 actcgagacg attaagcacg tggaacagct gctaagagag gtatttgtca tgatgtgata
5461 tttctaaaat tattatgaca cataataata caaaaatatt taaaatgcat gcatttagtc
5521 tgaagaatag taataacata aatgccatgc acccaataag cattgtaaaa taaatataaa
5581 caaaatcaat atactttcta agcaataaat gcatttttaa actcataatc aatttttcaa
5641 ctatggctaa atatttcatg atattactaa tgatacatga ggagtcttca aaaagtttgt
5701 ggaaaatgaa atttaaaaat aagtttaatt tagtacaaat gattttgaaa tcggtgcaaa
5761 gattcaattt ccagaaaaaa ttcattaaca atacagatta tgtaaaattt atgcatgatt
5821 tcaaagtgtt ctacacaaga ttaaacatct tttaatttaa ttttccgtga actttttgag
5881 tcatcctcat ataagtaaag gtatattagt acaattactt ccagattgga agctatgttc
5941 ctgtaatttt caaggtgaac atagtaatga aaggtgtaaa ggcagcaagg cagaaatcct
6001 caattgatca tttaccacct gtataaactg ggtcacatgt ttgtttgctc ttcaatgtct
6061 tcacctgtga gctaagagta tttgtaagga taccttctct gttatgttta tgagctggta
6121 tattcactta ttttacattt tgtaggtatt acagtaacat ttgttgaaaa tgctcgagta
6181 ttctcattac aaagatcaga gaagtgaggt acaccatcat tgagtccaca accatgtgat
6241 agtattacac tttaattaaa cagcagagct tgcttaaaga cccaggaagt ttcttggata
6301 acataaaacc ctatacttac atttatgtca tatatatgta actacaatat ttaaagcttt
6361 ttattttatg aatggattat ttgatgctca cacaaaatat tgtttaaatc aagttgccat
6421 ataaaattga tgcctcttga aagccctgag aaaactacct tttacctagg aaagtaatat
6481 tagactctag ctaggttatg ggtctcactg aattttgcta caaattaaaa ctggttttta
6541 ataaaacaaa aatcagaaca aacatcagaa ttgcttctct aagattgtaa aattgacctc
6601 cattcatgat gagaaagcaa tcttgtctat taccaacact ctatgttgaa agaccaacat
6661 tcataggcac caaagtgtac agcgtcagct ttccaagcaa ctcaggataa tgaaaaatta
6721 atgaaatcca caaattttta cttcactttg cttcatgcat tcacttatga agtgatgtta
6781 aggagtaatc tctctaagag cattttactc atttttcttc acatgaccca aggtaatttc
6841 taagcaagat aagtgaaaga tttttttttg tctttcactc agatgtggtt gtccaacaga
6901 caggagatta aatcattatg aattacaagg aaagttgaat catggactca aagattcttt
6961 tccttctttc caggagaaac tccaggataa aatcctcccc tttattcaat cactctttcc
7021 ttttgctgag cgcatcccct accctactct tccacagaac accctgaacc ttgctcaact
7081 cgacatgctg ctacctctcc ttcagcctga aataatggaa gaccccaagg ctaaagagac
7141 cattatccct aagcacaaac tgatgccctt ccttaaatct ccaaagacgg tcccctttgt
7201 tgactctcaa attctgaatc tcagggagat gaaaaatcaa caccttcttt tgccccagct
7261 cctgcccttc atgcaccagg tcttccagcc ttttccccag actcccattc cataccctca
7321 ggccctcctc tctcttcctc agtccaaatt catgcctatt gtcccacaag tggtgcccta
7381 ccctcaaagg gacatgccta tccaagccct tcagctgttc caagaactgc ttttccctac
7441 ccatcaaggc taccctgtgg ttcaaccaat agccccagtt aatgtaagtg caaacttact
7501 tattttgctg catcactcat agtgagttcg tgatgtgttt atgatggtgg aataagttca
7561 agagctctag gatgaaagaa caaaagtata aagaatggat ccaaaatcat attttatttt
7621 ttaaggattt atttagttat ttacttgaaa gagttacaca gagtgaggag aggcagagag
7681 agggagagag agaagtcttc catccactgg ttcactcccc aattggccac aacggcagga
7741 gctgcactgg tcggaagcca ggagccagga gccaggagcc aggagccagg agccaggagc
7801 ttcttctggg tctcaaggac ttgggtcatc ttctgctggc ttcccaggcc atagcagaga
7861 gctggatcgg aagtgaaaca gccgggtctt gaactggcac ccatatggga tgccggtgct
7921 tcaggcgagg gcattaaccc tctgagccac agtgctggcc cccaaaatca tattttagat
7981 ctgtgattct caatactagg tatactttgg gataacctgg agaactctta gactggagaa
8041 ctcccagtac tcaaattcca atgcaaaagc ccacccacag tattctgaca caattgtttt
8101 gctccaccat acagaaaaaa aattgtgttt gaaggaaaag attgtaggcc ctctgatttt
8161 cttggttagt tgagaaatct gagttaaggt agatcaaagt taattaaagc tagaattaaa
8221 tataattatc tgaacaggtc tgaaattaag aacatttagt attatctata gtttgaaaat
8281 ttttttatct tctattttta atatgtacac atgagggaaa aaatagaaat gctgacttca
8341 ttacattgaa caattttaag gcaagtgttt tccagtggtg aactgtatat ttattttgta
8401 tttatttatt ttaaaggtct aagaggattt cacagttaat atcttttcct gatttttggt
8461 aagttttgag actttggaga ttagactatt ttatagttga caaaacttta caactaattc
8521 ccctacatta acccaaaata gtggcagttt ccatcataga caaacttact tatcagatta
8581 ttctcaatgg ttgagtatta tttaccatta tatatctttt atattcacaa taacttttaa
8641 ttttatttat gtgttattga caaatctgac tggcttgctt ttaagggcca gtgtccttac
8701 atttggtatt cataatgctt aggaaaaaat aaaaactaga gcttctttta cttttttaaa
8761 agatttattt atttatttga aagtcagagt tacacacaga gagaaggaga ggcagagaga
8821 gagagagaca gagacacaaa gagagagaga gagagagaga gagagacagt gtcttccatc
8881 tgctgattca ctccccaatt cgctgcaaca gctggagctg caccgatcag aagccaggag
8941 cctgaagctt tctctgggtc tcctatgttg gtgcaggggc ccaaggactt ggaccatcct
9001 ctgctgcttt cccaggccac ggcagagagc tatattggaa gtggagcagc tgggacttga
9061 accagagtcc atatgggatg ccagcactgc agccagccac agcactggcc tcacttcttt
9121 tacttttata taaatatctt tgagctttag ttgaaaacca acttgcatta ctatttctgg
9181 tttaggcctt ataaaatttg tatttggttc acttaaattt gtcttttgaa ccatgattca
9241 aaataaaatt acttaatcta aatgtaagga ttaaaaaggg aagaggatga tagatacagt
9301 tatcttgact tggacattat agaaaatata acaaaacatc acatatcacc tcataaatgt
9361 atgggtgtaa agagacagag aaagagaaag gcagagaaag agaaagggaa agagaaagtc
9421 cccatctgct agtacattct tcaagtgttg acaatggcca ggactggact tgtaacagga
9481 gccaggaact cagnnnnnnn nnnnnnnnnn nngtctctta tatgtgtggc tggaacccaa
9541 tgacttaagt taacaattcc actgacatcc aaggtctgca ttggtgggga gctgaagtaa
9601 gaagccaaag tcaggaacca gtgtcaggcn ttccagtgtg ggatataggc atcttaacca
9661 ctaaccttaa tgctcactgt aaaatgtaca agctttatgt gttgatttaa aataagttaa
9721 aaaaaagaca aaacaaggaa gagaagatga tacttttagg atcttaatga cacaaaacct
9781 tttgtgataa cagactagat atttcagtaa aaaattaaag tgaactgata tttagaacct
9841 taggaatttt ctatatgtcc aaggaaaggc acaatagagt atatttgtga tacaattttt
9901 ttattaatta gtcacagcac aattacaaat ggaaaaggtt agcaatcatg tcatgtaacg
9961 taactaattt ttcatttgct ctgtattcca cagaattgac tgagactgga actttggcat
10021 cttctccgtc tttctatcat gtcatcagaa actaaatgtt ttttaactaa ccaatatggg
10081 caaatgaatc cttactcttt tatttatttt atgccttaaa tgaaatttca tttaatttga
10141 atttgacttg taagttgttt atacattaca aattgtaatt caggtagtac catcaaaatt
10201 caacattgaa ttggaaatgt tatagcaatg ccaaaatatg ttcaaaaata attcttacta
10261 ttatttcttt cagactctat ttcctttcca gtcatttcaa taaattaatc ctttaggcat
10321 acttaagttg ttctgtcttt attacatttc aaatgttatc attcttttta atgttaacct
10381 tagattatta ttgatgatga aaacaatcat ggaaaacttt tgatattgaa aaatgttttt
10441 tatgatttat tatttatttg agaggcagaa ttatagacag agagagggaa agacaaagag
10501 aaagatcttc catctcctgg ttcattcccc aaatggccac aatggctgga gctgggatga
10561 tccaaagcca gggatcaaga gccaggagct tcttctgggt ttcccacgta ggtgcaggga
10621 cccaaacact tagcatggtc tgctgctttc ccaggccgca gcagagagct ggatcagaag
10681 tggagcagct gggacttgaa ccagcgccca tatgggatgc tgacactaca gcaccagccc
10741 tgaatagaat cttttaagtt gaatattaaa agatatgaaa aggtggaaga aaagatagga
10801 tgattgcatg tttatctcat ttgctcctga aacatcttgg ttgatattca ttttccccat
10861 gcaatgattg aacttatgtt tttcaccaca cagaaaaaga gttaactaac attagacata
10921 acgttttgtg atcactcgaa ggaaagagct acaagtgtga aatgcgttta acagctccca
10981 cataattatc taagtgatgc tgtgagatgc actcacccat tatttcaatt tccatatcta
11041 tacagtagtc aggaatagac ttaggtattc ctaacatggc aggcattcct tgttgctcca
11101 cactgctcac accactgata ccagagcaan aangtattct atcacaatca gaatcaactg
11161 gattacatga attc
//