GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS HUMFUSED 555 bp ds-DNA SYN 20-MAR-1991
DEFINITION Human interleukin-1beta/growth hormone fusion protein gene,
complete cds.
ACCESSION M35049
KEYWORDS growth hormone; interleukin-1-beta.
SOURCE Human synthetic DNA.
ORGANISM Artificial gene
Artificial sequences; Genes.
REFERENCE 1 (bases 1 to 555)
AUTHORS Pecceu,F., Dousset,P., Shire,D., Cavrois,E., Marchese,E.,
Ferrara,P., Kaghad,M., Dumont,X. and Lupker,J.
TITLE Human interleukin 1-beta fused to the human growth hormone signal
peptide is N-glycosylated and secreted by chinese hamster ovary
cells
JOURNAL Gene 97, 253-258 (1991)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by F.Pecceu, 08-JUN-1990.
Author address: F.Pecceu
SANOFI ELF BIO-RECHERCHES
LABEGE INNOPOLE B.P. 137
31328 LABEGE CEDEX
FRANCE
FEATURES Location/Qualifiers
CDS 11..550
/note="human growth hormone/interleukin--1beta fusion
protein"
/codon_start=11
sig_peptide 11..88
/note="human growth hormone signal peptide"
/codon_start=11
mat_peptide 89..547
/note="interleukin-1-beta"
/codon_start=89
BASE COUNT 154 a 142 c 135 g 124 t
ORIGIN
1 agcttccgcc atggctacag gctcccggac gtccctgctc ctggcttttg gcctgctctg
61 cctgccctgg cttcaagagg gcagtgccgc acctgtaaga tctctgaact gcacgctccg
121 ggactcacag caaaagagct tggtgatgtc tggtccatat gaactgaaag ctctccacct
181 gcagggacag gatatggagc aacaagtggt gttctccatg tcctttgtcc aaggagaaga
241 aagtaatgac aaaatacctg tggcgttggg cctcaaggaa aagaatctgt acttaagctg
301 cgtgttgaaa gatgataagc ccactctaca gctggagagt gtagacccca aaaattaccc
361 aaagaagaag atggaaaagc gatttgtctt caacaagata gaaatcaata acaagctgga
421 atttgagtct gcccagttcc ccaactggta catcagcacc tctcaagcag aaaacatgcc
481 cgtcttcctg ggtggtacca aaggcggcca ggatataact gacttcacca tgcaatttgt
541 gagctcctag gatcc
//