GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC1 239 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 1.
ACCESSION M63415 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 1 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 239)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CAAT_signal 35..39
/gene="NMDMC"
exon 58..233
/number=1
/gene="NMDMC"
TATA_signal 77..80
/gene="NMDMC"
exon 100..233
/number=1
/gene="NMDMC"
BASE COUNT 22 a 82 c 85 g 50 t
ORIGIN
1 agatctccta ttggctccta cgccggctca ggggccaatg gggcgcgcgg gaggcggggc
61 tttcgtgggc ccggggtata gcttcgtggc ccgcgcgcgc gcttctctcc ggcgcgggca
121 ccggcgcgag ccatggcttc agtttccttg ttgtctgcgt tggctgtgcg gttgttgcgc
181 cccacgcacg gctgccaccc ccgcctacag cccttccacc tggcggcagt gcggtgagt
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC2 204 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 2.
ACCESSION M63439 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 2 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 204)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63415:234..239,1..14)
/number=1
/note="4.5 kb gap."
/gene="NMDMC"
exon 15..198
/number=2
/gene="NMDMC"
BASE COUNT 58 a 49 c 58 g 39 t
ORIGIN
1 ggttcaccat gcagaaatga agccgttgtc atttctggaa ggaaactggc ccagcagatc
61 aagcaagaag tacagcagga ggtggaagag tgggtggcct caggcaacaa gcggccacac
121 ctcagtgtca ttctggttgg tgacaatccc gccagtcact cctatgttct caacaaaacc
181 agggcagcag ctgaagtggt aagt
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC3 144 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 3.
ACCESSION M63440 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 3 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 144)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63439:199..204,1..14)
/number=2
/note="1.4 kb gap"
/gene="NMDMC"
exon 15..138
/number=3
/gene="NMDMC"
BASE COUNT 44 a 32 c 35 g 33 t
ORIGIN
1 ctttcttaca atagggaatc aacagtgaga caattgtgaa accagcctca gtttcagagg
61 aagagctgct gaattcaatc aggaagctga acaacgatga gaacgtagat ggcctccttg
121 ttcagctgcc actcccaggt gagt
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC4 173 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 4.
ACCESSION M63441 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 4 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 173)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63440:139..144,1..14)
/number=3
/note="700 bp gap"
/gene="NMDMC"
exon 15..167
/number=4
/gene="NMDMC"
BASE COUNT 41 a 32 c 52 g 48 t
ORIGIN
1 gatttctgtt ttagagcaca ttgatgagag gaaggtctgc aatgccgttt ctcctgacaa
61 ggatgttgat ggctttcatg tcattaacgt ggggcgaatg tgcttggacc agtactctat
121 gctgccagca accccatggg gcgtgtggga gataattaag cgaacaggta ggt
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC6 113 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 6.
ACCESSION M63443 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 6 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 113)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63442:123..128,1..14)
/number=5
/note="800 bp gap"
/gene="NMDMC"
exon 15..107
/number=6
/gene="NMDMC"
BASE COUNT 33 a 30 c 22 g 28 t
ORIGIN
1 tttttgcctc tcaggtgatg ccacagtcac aatatctcat cgatacactc ccaaagagca
61 gctgaagaag cacacgatcc ttgcagacat tgtaatatct gccgctggta aga
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC5 128 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 5.
ACCESSION M63442 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 5 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 128)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63441:168..173,1..14)
/number=4
/note="700 bp gap"
/gene="NMDMC"
exon 15..122
/number=5
/gene="NMDMC"
BASE COUNT 33 a 25 c 41 g 29 t
ORIGIN
1 atttatcttt gcaggcattc caaccttagg gaagaatgtg gtagtggctg gcaggtcaaa
61 aaacgttgga atgccgattg caatgttgct gcacacagat ggagctcacg aacggcccgg
121 gggtgagg
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC7 146 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 7.
ACCESSION M63444 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 7 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 146)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63443:108..113,1..14)
/number=6
/note="700 bp gap"
/gene="NMDMC"
exon 15..140
/number=7
/gene="NMDMC"
BASE COUNT 43 a 28 c 37 g 38 t
ORIGIN
1 ctctctgtca ctaggcattc caaatctgat cacagctgac atgatcaagg aaggagcagc
61 ggtcatcgat gtgggaataa acagagttca agatcctgtc actgcaaagc ccaaattggt
121 tggagatgtg gattttgaag gtattt
//GenBank-Updates@genbank.bio.net (03/20/91)
LOCUS MUSNMDMC8 1119 bp ds-DNA ROD 20-MAR-1991
DEFINITION Mouse NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase gene, exon 2.
ACCESSION M63445 M37088
KEYWORDS NAD-dependent methylenetetrahydrofolate dehydrogenase;
methenyltetrahydrofolate cyclohydrolase.
SEGMENT 8 of 8
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Isolation and characterization of cDNA clones encoding the murine
NAD-dependent methylenetetrahydrofolate dehydrogenase-
methenyltetrahydrofolate cyclohydrolase
JOURNAL J. Biol. Chem. 264, 4837-4843 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1119)
AUTHORS Belanger,C. and MacKenzie,R.E.
TITLE Structural organization of the murine gene encoding NAD-dependent
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate
cyclohydrolase
JOURNAL Gene 97, 283-288 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
intron order(M63444:141..146,1..14)
/number=7
/note="2 kb gap"
/gene="NMDMC"
CDS join(M63415:133..233,M63439:15..198,M63440:15..138,
M63441:15..167,M63442:15..122,M63443:15..107,
M63444:15..140,15..178)
/EC_number="1.5.5.15"
/EC_number="3.5.4.9"
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
/codon_start=133
mRNA join(M63415:58..233,M63439:15..198,M63440:15..138,
M63441:15..167,M63442:15..122,M63443:15..107,
M63444:15..140,15..839)
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
mRNA join(M63415:100..233,M63439:15..198,M63440:15..138,
M63441:15..167,M63442:15..122,M63443:15..107,
M63444:15..140,15..839)
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
mRNA join(M63415:100..233,M63439:15..198,M63440:15..138,
M63441:15..167,M63442:15..122,M63443:15..107,
M63444:15..140,15..1119)
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
mRNA join(M63415:58..233,M63439:15..198,M63440:15..138,
M63441:15..167,M63442:15..122,M63443:15..107,
M63444:15..140,15..1119)
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
sig_peptide join(M63415:133..233,M63439:15..18)
/number=8
/gene="NMDMC"
/codon_start=133
mat_peptide join(M63439:19..198,M63440:15..138,M63441:15..167,
M63442:15..122,M63443:15..107,M63444:15..140,15..175)
/product="NAD-dependent methylenetetrahydrofolate
dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
/gene="NMDMC"
/codon_start=19
exon 15..839
/number=8
/gene="NMDMC"
exon 15..1119
/number=8
/gene="NMDMC"
BASE COUNT 281 a 240 c 276 g 322 t
ORIGIN
1 ttgtttctat gcaggagtca agaagaaagc tggttatatc actcccgtcc ctggtggtgt
61 gggtcccatg accgtggcca tgctcatgaa gaacaccatt attgccgcaa agaaagtgct
121 aagaccagag gagctggaag tgttcaagtc caaacagcgc ggagtcgcca ccaactagca
181 gcactctgag ccagcccgag aggctaagca ggccaagagg aatgcagtgt ttttaattta
241 ttctgtcgaa atggtttaaa atgtttgtat ttattgaaag cttaaacggg tggctgtgtg
301 cgcgcatggc tctacagaac ctcaccagga tgcccatcag ttgtcctgcc tttgacctgg
361 tgatgcacag gagacgtcct cacaccgaga gtggatgctg aacttcatca aaaaaaaaaa
421 aaggtctgcc gttttaggct ctcatttccc aagtgctatt ccaatacaag ttgatgactc
481 atcttaggtc ccaagccttt gagttcaact ttcaaaccaa aggaaacctt agtagaggaa
541 atgaagggaa aggaagagaa agcagcacag ggtttcaacg gcactccctt actctctcgg
601 gagtgcagcc aggagtgctc cgattgccct gaggagagct cagctggctg ggcctagctg
661 tccccctgtg gcgggtcgtc agggaagggt tagagtctcc ccacttgctg ttatcctcct
721 gtgagcttgt cctatctatt ttaattttct agaatcgaaa aagctcattt tataaatgat
781 gtgtgtatta tcacgtttgg cttttgcagc acatttaaac ttttaagttt cagactgtta
841 agagagttgt gtgtctgttt tctttggcgg gtgctttgag gcctatttgt ttttgaaaaa
901 caaaacaaaa cttgtgcgtg ataatcacga gggcagctcg tgccaccaaa gaactgtcag
961 cagctgcctg cacgtctttc acgttacccc gttggctttc ctgtaagcta tccaggagct
1021 tgggttaata taagacttag tcggattttc ttattaaagg gttttcttgc agttgggttt
1081 tttgtttgtt tttaaataaa gctcatctgt cgggtgtgg
//