GenBank-Updates@genbank.bio.net (03/21/91)
LOCUS HUMMGDMT 744 bp ss-mRNA PRI 21-MAR-1991
DEFINITION Human O-6-methylguanine-DNA methyltransferase mRNA, complete cds.
ACCESSION M60761
KEYWORDS O-6-methylguanine-DNA methyltransferase.
SOURCE Human Raji cell line, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 744)
AUTHORS Koike,G., Maki,H., Takeya,H., Hayakawa,H. and Sekiguchi,M.
TITLE Purification, structure, and biochemical properties of human
O-6-methylguanine-DNA methyltransferase
JOURNAL J. Biol. Chem. 265, 14754-14762 (1990)
STANDARD full staff_entry
REFERENCE 2 (sites)
AUTHORS Hayakawa,H., Koike,G. and Sekiguchi,M.
TITLE Expression and cloning of complementary DNA for a human enzyme that
repairs O-6-methylguanine in DNA
JOURNAL J. Mol. Biol. 213, 739-747 (1991)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS 16..639
/product="O-6-methylguanine-DNA methyltransferase"
/gene="methyltransferase"
/codon_start=16
polyA_site 744..744
/gene="methyltransferase"
BASE COUNT 162 a 194 c 246 g 142 t
ORIGIN
1 ttggtacttg gaaaaatgga caaggattgt gaaatgaaac gcaccacact ggacagccct
61 ttggggaagc tggagctgtc tggttgtgag cagggtctgc acgaaataaa gctcctgggc
121 aaggggacgt ctgcagctga tgccgtggag gtcccagccc ccgctgcggt tctcggaggt
181 ccggagcccc tgatgcagtg cacagcctgg ctgaatgcct atttccacca gcccgaggct
241 atcgaagagt tccccgtgcc ggcacttcac catcccgttt tccagcaaga gtcgttcacc
301 agacaggtgt tatggaagct gctgaaggtt gtgaaattcg gagaagtgat ttcttaccag
361 caattagcag ccctggcagg caaccccaaa gccgcgcgag cagtgggagg agcaatgaga
421 ggcaatcctg tccccatcct catcccgtgc cacagagtgg tctgcagcag cggagccgtg
481 ggcaactact ccggaggact ggccgtgaag gaatggcttc tggcccatga aggccaccgg
541 ttggggaagc caggcttggg agggagctca ggtctggcag gggcctggct caagggagcg
601 ggagctacct cgggctcccc gcctgctggc cgaaactgag tatgtgcagt aggatggatg
661 tttgagcgac acacacgtgt aacactgcat cggatgcggg gcgtggaggc accgctgtat
721 taaaggaagt ggcagtgtcc tggg
//