GenBank-Updates@genbank.bio.net (03/23/91)
LOCUS MUSMHH2DKF 880 bp ss-mRNA ROD 23-MAR-1991
DEFINITION Mouse MHC class I H-2D-k mRNA (H-2-b x H-2-k), partial cds.
ACCESSION M58595
KEYWORDS cell surface antigen; cell surface glycoprotein; class I gene;
integral membrane protein; major histocompatibility complex.
SOURCE Mouse (strain (C3HeB x C57BL/6J)F1, haplotype H-2-b x H-2-k) IE-7
cell, cDNA to mRNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 880)
AUTHORS Aboud,M., Askenazi-Rydel,M., Har-Vardi,I., Weinstein,Y., Gopas,J.
and Segal,S.
TITLE Changes in the coding sequence of the H-2D-k gene of metastatic
cells that might account for immunogenic abnormality of its encoded
antigen
JOURNAL Biochem. Biophys. Res. Commun. 171, 1395-1401 (1990)
STANDARD simple staff_review
FEATURES Location/Qualifiers
CDS 1..880
/product="MHC H-2D-k glycoprotein"
/gene="H-2D-k"
/codon_start=2
/partial
mutation 191..191
/note="t in IE-7 cells; c in wt"
mutation 246..246
/note="a in IE-7 cells; t in wt (Tyr->Phe)"
mutation 399..399
/note="c in IE-7 cells; g in wt (Ser->Trp)"
mutation 733..733
/note="a in IE-7 cells; g in wt"
BASE COUNT 192 a 227 c 299 g 162 t
ORIGIN Chromosome 17.
1 gcgcttcgac agcgacgcgg agaatccgag agatgagccg cgggtgcggt ggatggagca
61 ggaggggccg gagtattggg aacgggagac acagatcgcc aagggcaatg agcagagttt
121 ccgagtggac ctgaggaccc tgctccgcta ctacaaccag agcgagggtg gctctcacac
181 gatccagcgg ttgtccggct gtgacgtggg gtcggactgg cgcctcctcc gcgggtacga
241 gcagtacgca tacgacggct gcgattacat cgccctgaac gaagacctga aaacgtggac
301 ggcggcggag atggcggcgc tgatcaccaa acacaagtgg gagcaggctg gtgctgcaga
361 gagagaccgg gcctacctgg agggcacgtg cgtggagtcg ctccgcagat agctggagct
421 cgggaatgcg acgctgctgc acacagattc cccaaaggca catgtgaccc atcaccccag
481 atctaaagtt gaagtcaccc tgaggtgctg ggccctgggc ttctaccctg ctgacatcac
541 cctgacctgg cagttgaatg gggaggagct gacccaggac atggagcttg tggagaccag
601 gcctgcaggg gatggaacct tccagaagtg ggcatctgtg gtggtgcctc ttgggaagga
661 gcagaattac acatgccata tgtaccatga ggggctgcct gagcccctca ccctgagatg
721 ggagcctcct ccatccactg agtcttacat ggtgatcgtt gctgttctgg gtgtccttgg
781 agctgtggcc atcattggag ctgtggtggc ttttgtgatg atgatgagga gaaacacagg
841 tggaaaagga ggggactata ctctgactcc aggctcccag
//