GenBank-Updates@genbank.bio.net (03/23/91)
LOCUS HUMSCLA 5000 bp ds-DNA PRI 23-MAR-1991
DEFINITION Human stem cell protein mRNA, complete cds, and genomic DNA.
ACCESSION M61108
KEYWORDS stem cell protein.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 5000)
AUTHORS Aplan,P.D., Begley,C.G., Bertness,V., Nussmeier,M., Ezquerra,A.,
Coligan,J. and Kirsch,I.R.
TITLE The SCL gene is formed from a transcriptionally complex locus
JOURNAL Mol. Cell. Biol. 10, 6426-6435 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
exon 1..118
/number=IIa
/gene="SCL"
intron 119..420
/gene="SCL"
CDS 578..1573
/function="hematopoietic differentiation"
/product="stem cell protein"
/gene="SCL"
/codon_start=578
polyA_signal 4981..4986
/gene="SCL"
polyA_site 5000..5000
/gene="SCL"
BASE COUNT 1078 a 1305 c 1359 g 1258 t
ORIGIN
1 gcccgggact atcccttcgc ggtgtagcgg cagccggaga cctggctgag gaggcaaccg
61 cgtagacacc tccctgctta gaaaacaaac actgaaccag accgatccca gttggagggt
121 tcgaaaatgt tccagacagc ctgtcgggag gggttgttgt tgctgttgga ctaaatagct
181 attcctgatt ggtcatgtat agggtttttt aaggcgggtg gggggaggag ggggtagagg
241 aaaggctcca aacacctgca ggttgggggc ggaaagctgt ttgcgattcc ctggactggt
301 tggtcgggga caggaggtaa ttcccagcca ttgaccccca tttctctctc tccctccctc
361 ttgccctgcc tctttctctc cacccctatc tttcctggaa actcgctttg ggcgcggcag
421 atcgcccagg accacaccgc agcgtaactg caggcctctc agcgaaaaag ggggaaagca
481 aagacccggg tgtgcatcct cttcctcggc ttccgcccct ttccggcgga gtggagatcc
541 tattcagagg ggccggtctc tctaaatatg ccccaggatg accgagcggc cgccgagcga
601 ggcggctcgc agtgaccccc agctagaggg acgggacgcg gccgaggcca gcatggcccc
661 cccgcacctg gtcctgctga acggcgtcgc caaggagacg agccgcgcgg ccgcagcgga
721 gcccccagtc atcgaactgg gcgcgcgcgg aggcccgggg ggcggccctg ccggtggggg
781 cggcgccgcg agagacttaa agggccgcga cgcggcgacg gccgaagcgc gccatcgggt
841 gcccaccacc gagctgtgca gacctcccgg gcccgccccg gcccccgcgc ccgcctcggt
901 tacagcggag ctgcccggcg acggccgcat ggtgcagctg agtcctcccg cgctggctgc
961 ccccgccgcc cccggccgcg cgctgctcta cagcctcagc cagccgctgg cctctctcgg
1021 cagcgggttc tttggggagc cggatgcctt ccctatgttc accaccaaca atcgagtgaa
1081 gaggagacct tccccctatg agatggagat tactgatggt ccccacacca aagttgtgcg
1141 gcgtatcttc accaacagcc gggagcgatg gcggcagcag aatgtgaacg gggcctttgc
1201 cgagctccgc aagctgatcc ccacacatcc cccggacaag aagctcagca agaatgagat
1261 cctccgcctg gccatgaagt atatcaactt cttggccaag ctgctcaatg accaggagga
1321 ggagggcacc cagcgggcca agactggcaa ggaccctgtg gtgggggctg gtgggggtgg
1381 aggtggggga gggggcggcg cgcccccaga tgacctcctg caagacgtgc tttcccccaa
1441 ctccagctgc ggcagctccc tggatggggc agccagcccg gacagctaca cggaggagcc
1501 cgcgcccaag cacacggccc gcagcctcca tcctgccatg ctgcctgccg ccgatggagc
1561 cggccctcgg tgatgggtct gggccaccag gatcagccag gagggcgttc ttaggctgct
1621 gggatggtgg gcttcagggc aggtggggtg agaattgggc ggctctgaag caaggcggtg
1681 gacttgaact ttcctggatg tctgaacttt gggaagcctt tactgaccct ggggctggct
1741 tttctgtttc ctgtaccagt aggagatcag aaaaatggag caaagtggta ggtacttttt
1801 gtgaagacgg cacggtcttc cctcttccct cagtcccaaa tccttcccaa gtaagaggct
1861 ggagttgtca ctgcttttgg cctggagttt gggatccctg tctttcctaa gacctggggt
1921 tgtcagctct catctgaggc atccagcagt ctctgccttg cctttagccc ctcccaagct
1981 ggctggggtg gcctgtgtgg ccacttctgt ccatatttat aggtacccaa tagctgccca
2041 tttcgtgagc cccatcttca cccaggccta tgttgatcca tccagcttgc cagatgctgc
2101 agagtcacaa gcctcgaggt gccttcttca gggcctggtt gaagaagatg atcagtggac
2161 agtctgctct agatgagctg ggccggaggg tcaggaaacc cagtcgccct tacttcttgc
2221 cctggggatc aaagttctgc tttctcccca atgagacttg ccttcctaag cctgtggctg
2281 tggagaccat gtctgcagcc ctgagaaagc cctgtcgggc tttgtgtgaa ggcagagaaa
2341 gggacaatga tagtagagtg atatggagca agagatattt tgggcatgtg ggcttcaact
2401 cctcgacatc actgttcatg ctggcgagtg aatgccagtg tgctgatggg cgtacgctgg
2461 tgctgagtag atgcgcagcc ccatctgtgc attctcctgg atgcttagag ggatttcttt
2521 gctgtaagat gtctgtttgc tgatggtctg gtctatgttc cgaattgagc acaaaacctg
2581 tcctatgaat gctttgcatt tggaattttt gcttgacttc agttattggt ggaatcttta
2641 gcgctcaata ggaccaggat ccagcctcac ttctagggta tgggaaatcc aatcagagac
2701 caggccctgg ctagacccaa acatatgcac attcacttag cagaacctta aacacccctc
2761 agttgtgcag cttttggtca tcaagggtgc gtctgggagg ttggtttaat gcaatagaag
2821 tgctcccctc tgaaagttgt acatgaaatt tttgtaaatc acatccttat ccttcatctt
2881 ttaaagaaat aaccactgca agtccttttg taaagtgaag aatccttttg tagaatgaac
2941 cactgcccct tcattgattt cctgtgtcaa tccagatggt gggatgtggt tttcttaagg
3001 tgaggcctgt ctgtgacctg catctaagcc catgggacaa attgcacaga agtcctgtat
3061 gtctgtcatt gtacccttaa gtcaccctag ccctctccct ctaggctctg ccttcgaggt
3121 cagaggagag atagcctgtg gccctgtcct gccatgcaag aactcatcac tgtggctgtc
3181 tggaaagccc ccccttatag tttgggcttc agcctagtgg cttgtcctca ccatgatggg
3241 gccctaattc agccatgtac agacagagaa tatgtctgct cctttcccct tccttttaag
3301 taaggtccaa ttctcgagct tggggcaaca ttgttcacct ttgtagcact caggctctcc
3361 attcaatttc aggctcccca gatcatgttt tggtgaaaat tagggttggt tcctttccaa
3421 cgtttggaag atcctgtgag gagccccatc tgtctaaaga tagagtcatt gctgtaggat
3481 ctaaggctgt ttgcttcacc gtggattcgc ttgagttagg aatgagaagt agccacagta
3541 tggatgggtg gatgggtttt atgagatgga tcacatattt tattaagaac tcaaacttct
3601 ggctccctct tctttcagac ttgccatgtg actctggctt ggcctatctc ctagggctat
3661 ggtgtggact gaatgggatc atgaaagtag acagttttga gaacgtaaag aactttttct
3721 tttccctcaa tctcaatcct gcagtggggt ttcgcagcct gagtccacga cctaggcagt
3781 aggccggtgt gcctgactgc ccagcatttg ggtaatttag attgtaaacc gctttggcct
3841 gagttattga gattgtcctc atttctccag attatctatt tgtgtgtgtg tgtgtgtgtg
3901 tgtgagagac ggtgtcttgt tctgtcactc aggctggagt acagtggtgc catcattgct
3961 gtctgcagcc ttgaactctg ggctcaagca atcctctcac ctcagcctcc cgagtaggga
4021 ggaccacagg tgtgagccac cacacctggc taatttttac tttttttttt ttttggtaga
4081 gatggagtct tgctatattg cccaggctgg tcttgaagtc ctggcttcag gcaattctcc
4141 tgcctttgcc tccagaagca ctgggatcac aggtgtcagc cattgcaccc agcccagatt
4201 gtcttaattt ctatcttgtt ccaaggccag ggacagtaat aagaatggaa aagagatatg
4261 ggaacactgg cagactgtgt aaaatgtaat gcaactaccc aaaacaagcc tggtaggaaa
4321 gggcaagtct ttaggtcttt gtaagaacta aagaagatct gtaattttta ttttcaccct
4381 ctgtacccca tgaccttatc cttcctctcc ttccttgtta cccatgaaaa actggcaaca
4441 ttccaagaat agcatctgta caaaggggaa agaacataaa ggtaaaacaa aacaaaacaa
4501 cattttgaga acaaagatga ccataaccac tgaagggaat cacatctttt aagacaaatt
4561 catattcttt tatttgttat ggcagatgac aagatggtac aacctttatt cttttccaaa
4621 ataaaacaaa gggcacagca tctgtagtca gccgacaact ctttcggcct tttgggggtg
4681 ggtctggccg tacttgtgat ttcgatggta cgtgaccctc tgctgaagac ttgccccctg
4741 cccgtgtaca tagtgcattg tttctgtggg cgggcccagc actttccgtc aacgttgtac
4801 tgtatgtgat gaattgcgtt ggtctctgca tttttctgca gaagaggagt aaccgctcca
4861 ggtaccttga cctttgtaca gcccagaggc caacactgtg ggtgtgtgac tctttagcaa
4921 aaaaaaccca tgtggtgatg atgtgtctat atatgtgagg atgtatcggg aagatttcta
4981 aataaaagtt ttacaaaggg
//