[bionet.molbio.genbank.updates] Human guanine nucleotide-binding regulatory protein

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ01    1976 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exons 1 and 2.
ACCESSION   M60156
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            <1561..1678
                     /number=1
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
     exon            1899..1941
                     /number=2
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT      288 a    762 c    596 g    330 t
ORIGIN
        1 cggctgggat ctcggagcag ggtcggctat ggccctggag gcagcggctc acagagaaaa
       61 agctctggct tttctccgcc cgctgcgttc ctcttcttac agcctcgggt gtcacatatt
      121 aggtgctcaa taaatgtgga cataggaaac gaaaagtccg aatctgtcct tacgccccca
      181 agcgaattct ggggcgcgcg ggtttattcc gacccactac cacatcgcgt ttcctgaggt
      241 aacccggcct cggctctgcg gccccagcgg ctggagagcc acggagaagg cgggctacgg
      301 gcgacaagat ggagagccgg cccgagaggg acagaggccg cgctggcagc gagctggggg
      361 gcccacctga ccgtcctgcg ggcagcccgg ccccgcgctc ccattgacaa ggaggtccgc
      421 cgccggcgcg tggggcggga gcggaggcgg ggtgggcgcc ccggcgcgcg cccggcccca
      481 ctccccgccc ccgccagtcc cgcaagcacc caccccgggg gagccgcggg ccgggagggc
      541 gctgggggga ggggcaggcc tccgcgacgc gtgtgcgcgg cggcggccgg tgacgcgaac
      601 tgcggcgcgc gcctcccccg ccccgcgccc tccgtcccgg gggcccggcg cgcggccctg
      661 ctgacgtcag ctggcggccc gcggagccgg gtgcgcagag ccgtggcgca gcgtcgcgcg
      721 tgcgctggcc tcctccccgc cccgggccca ggcgcgcgcg cgcttgttcg ctctcccatt
      781 ttttttttcc cctccctccc tgcctctctc tctctccctc tccctcgagc tcccggctgg
      841 ctgcggctcc ctggcgctct ccctctctct ccggtaggct caccgagcga tgcgagctct
      901 gggagacagc gacgccgcct cccgctagag acctgcccct cggcccggcc ccctgcccaa
      961 ccctgcccag cgcgcggggg tcggcgaagg cgccgcggac gcaccgacgg ctgaagagcg
     1021 gcgatgcaca tgcactagca gcacccccta actcactccc tccacatccc gcgccgccgc
     1081 cgccgcctcc tccacctcct cctccgccgc cgccgcctcc tcctcctccg gcagccgcgg
     1141 cagcaggacc caccctgccc cccaccccac cctctgtcgg ctccggctgc ggctccagcc
     1201 tcgactatta ttttatttat tttgggtcgt gcacaagcct cagtgcctgc agtccgcgcc
     1261 tcctcggccc gcgggcgcct cctcccttgg ctccggagcc ccagaccccg gccaccctcg
     1321 attcgacaac cccagacccc tgccagctgc cgcgagtctc cgctgctgga atcttgttag
     1381 cggctgtctt tttggagggt tctggtttcc cgacattttt gtttccagcc caggagagga
     1441 tatcgtgatt ttcccccctt gagccagccc aggctctgct ctctgggggg gtggggggcg
     1501 ctccaagccg gggagccgtg ccagccgagt cgtgcgggct gtggcaggga aggggccacc
     1561 atgggatgta ctctgagcgc agaggagaga gccgccctcg agcggagcaa ggcgattgag
     1621 aaaaacctca aagaggatgg catcagcgcc gccaaagacg tgaaattact cctgctcggt
     1681 aaggaccgcc gctgctaccc ccatcccccg accccggcca ctccgcaccc cctgccacca
     1741 gctcccccac cccactcgcg cccgggagac ctggtcccca agttggcacc accatgtgcc
     1801 caggatcgcc caccccctcg catgccttag tccccccctc cccctgttcc cttaagctga
     1861 cactcaccag tttttcccca ctgtctgtgt cccaacaggg gctggagaat caggaaaaag
     1921 caccattgtg aagcagatga agtaagtccc tgtggcattg ggattcgtac ttttat
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ02     185 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 3.
ACCESSION   M60157
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 185)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..163
                     /number=3
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       47 a     44 c     51 g     43 t
ORIGIN
        1 gtgtgtgtgg tttttctcta ggatcatcca tgaagatggc ttctccggag aagacgtgaa
       61 acagtacaag cctgttgtct acagcaacac tatccagtcc ctggcagcca tcgtccgggc
      121 catggacact ttgggcatcg aatatggtga taaggagaga aaggtaggcc cctgagccca
      181 taagc
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ03     299 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 4.
ACCESSION   M60158
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..180
                     /number=4
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       63 a     78 c     97 g     61 t
ORIGIN
        1 catccacctc tcctcacagg ctgacgccaa gatggtgtgt gatgtggtga gtcggatgga
       61 agacaccgag cccttctctg cagagctgct ttctgccatg atgcggctct ggggcgactc
      121 aggaatccaa gagtgcttca accggtcccg ggagtatcaa ctcaacgact ctgccaaata
      181 gtgagtgtcc cagcggcgca tggcctggag ccgggcagtg atgcgggagt ggaagggact
      241 gtgatgggat ggcagagcaa ggaggattct cgctgagtca cgctccggag attctccat
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ04     189 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 5.
ACCESSION   M60159
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 189)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..150
                     /number=5
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       44 a     65 c     48 g     32 t
ORIGIN
        1 cctgtttgtt gccatcctca gctacctgga cagcctggat cggattgggg ccgccgacta
       61 ccagcccact gagcaggaca tcctccgaac cagggtcaaa accactggca tcgtagaaac
      121 ccacttcaca ttcaagaacc tccacttcag gtgaggccca gagaggcccc caggccctgg
      181 cgagggcta
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ05     189 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 6.
ACCESSION   M60160
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 189)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..151
                     /number=6
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       35 a     59 c     60 g     35 t
ORIGIN
        1 ccagctccct gcctcctaca ggctgtttga cgtcggaggc cagcgatctg aacgcaagaa
       61 gtggatccat tgcttcgagg acgtcacggc catcattttc tgtgtcgcgc tcagcggcta
      121 tgaccaggtg ctccacgaag acgaaaccac ggtgagtggc ctgggccccc cgggcagggg
      181 gcagcgctg
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ06     184 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 7B.
ACCESSION   M60161
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 184)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..173
                     /number=7B
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       55 a     54 c     32 g     43 t
ORIGIN
        1 cccctccact ctgttgcaga accgcatgca cgaatccctg aagctttttg acagcatctg
       61 caacaacaaa tggttcacag acacgtccat catcctgttt cttaacaaga aggacatatt
      121 tgaagagaag atcaagaagt ccccgctcac catctgcttt cctgaatata caggtagaga
      181 cccc
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ07     291 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 8B.
ACCESSION   M60162
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            21..>208
                     /number=8B
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       61 a    112 c     66 g     52 t
ORIGIN
        1 tgccttgttt tgctctgcag gccccagcgc cttcacagaa gccgtggctt acatccaggc
       61 ccagtacgag agcaagaaca agtcagccca caaagagatc tacagccacg tcacctgcgc
      121 cacggacacc aacaacatcc agtttgtctt tgatgctgtg acggacgtca tcatcgccaa
      181 aaacctgcgg ggctgtggac tctactgagc ccagccgccc tgcccggcac ccttgccctg
      241 cctggcctgc cgcccccccc tccccctgga accaagctcc accagtctca g
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ08     183 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 7A.
ACCESSION   M60163
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 183)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..173
                     /number=7A
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       45 a     57 c     32 g     49 t
ORIGIN
        1 tcccttcctg cggccgcaga accgcatgca cgagtctctc atgctcttcg actccatctg
       61 taacaacaag ttcttcatcg atacctccat cattctcttc ctcaacaaga aagatctctt
      121 tggcgagaag atcaagaagt cacctttgac catctgcttt cctgaataca caggtgggtg
      181 cca
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ09     289 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 8A.
ACCESSION   M60164
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            21..237
                     /number=8A
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       81 a     88 c     55 g     65 t
ORIGIN
        1 tcttctgtgt cttgttacag gccccaatac ctatgaagac gcagccgcct acatccaagc
       61 acaatttgaa agcaaaaacc gctcacccaa caaagaaata tattgtcaca tgacttgtgc
      121 cacagacacg aataacatcc aggtggtgtt cgacgccgtc accgacatca tcattgccaa
      181 caacctccgg ggctgcggct tgtactgacc tcttgtcctg tatagcaacc tattttggta
      241 atgattccag cacccacaga acagcttgcg tgcgcgcgca tacacacac
//

GenBank-Updates@genbank.bio.net (03/22/91)

LOCUS       HUMGOAQ10    1439 bp ds-DNA             PRI       22-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 9.
ACCESSION   M60165
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     mRNA            join(M60156:<1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60163:20..173,M60164:21..237,46..>1166)
                     /product="guanine nucleotide-binding regulatory protein 1"
                     /gene="Go-alpha"
                     /partial
     mRNA            join(M60156:<1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60161:20..173,M60162:21..>208)
                     /product="guanine nucleotide-binding regulatory protein 2"
                     /gene="Go-alpha"
                     /partial
     CDS             join(M60156:1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60163:20..173,M60164:21..208)
                     /product="guanine nucleotide-binding regulatory protein 1"
                     /gene="Go-alpha"
                     /codon_start=1561
     CDS             join(M60156:1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60161:20..173,M60162:21..208)
                     /product="guanine nucleotide-binding regulatory protein 2"
                     /gene="Go-alpha"
                     /codon_start=1561
     exon            46..>1166
                     /number=9
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT      385 a    376 c    289 g    389 t
ORIGIN
        1 tcacagaaaa tggtcagact ggacccctta tctctctctc tacagactgc ttcacggact
       61 ctttgctgtt gacgttgatc tcctggtagc atgacctttt ggcctttgta agacacacag
      121 cctttctgta tcaagcccct gtctaaccta cgaccccaga gtgactgacg gctgtgtatt
      181 tctgtagaat gctgtagaat ccggttttag ttgagtcttc acatttagaa tttgaaagga
      241 aaaacagaac atttctcatg tgctttgtag cttaaaaaaa ggaaaactca ccatttcaac
      301 catatttctt tttcttgcaa aacaaacata cccatctgca ccgacgcctg ccccgtccca
      361 cctcgcgcga gcccctggag ctcctgctgg gggaggccca tctgccgcct ggggctccgg
      421 tgcggtgcat ggtccgagga gtgtgctcag gccgggcttt ccagaaggca caggccactg
      481 caaaccctgc tgctgccggc cgcccagaca ccacagacgc cactggcggc cctaagccac
      541 tcccgccaca cgctcactcc aggttcgtat agaaaaagca cagctctcac tggccagtag
      601 ctgccaaaaa gaacacccat cgtataagga aatccagccc catagaaaac aatctgccca
      661 ccgaccccct ttctaaggat agcctttgta ggggtttttt ggttcctttt tttttttttc
      721 agtttgtgtt tttacttttg tcccgccgag tactatgtat taccagcccc cacccacaga
      781 tcagtttcct agtctttggg aaacgggttg tgtttttttt cctttgccgt gttggatttc
      841 cggtcgcggc tgacacctcc cttcgtgtgt gcgcccctcc ccacccctgc ctgtgttctg
      901 tgccctgtgt ccgctctctc atgtggggat gtttgtgctg cagacaaaaa gaacaaaaaa
      961 aaatttttaa ataccacaag atggaaaaaa aaaacaaaaa aatttaaaaa gatggaatgt
     1021 agtgtttaca ttaaagccgc cgttttcatg accaatccta tgtcatttct actttgacta
     1081 atacccaaac cctaaacctc ttcacggttt cacttttaag acttaatctg tgctgaagaa
     1141 gaccagtcac agccatttca aataaagagg aggcaaaaag acaaaacaca caaaaaatta
     1201 aaaaaaaaaa cttaaaaaaa aaaggaaaaa agaaaaaaaa gcccacgggt ctttgtaagc
     1261 ctttctattc ccaatcggtg aggtttctgt gatatcttac acactgccag tctacttctc
     1321 tgactaatgg aaaattcctg tgtagctcaa taaaagagaa tgtttgtctg tactcctgag
     1381 tctcaccctg tgccttccaa cgatggttat ttggggtggg cttcattctg gcaggagag
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ01    1976 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exons 1 and 2.
ACCESSION   M60156
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     1 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            <1561..1678
                     /number=1
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
     exon            1899..1941
                     /number=2
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT      288 a    762 c    596 g    330 t
ORIGIN
        1 cggctgggat ctcggagcag ggtcggctat ggccctggag gcagcggctc acagagaaaa
       61 agctctggct tttctccgcc cgctgcgttc ctcttcttac agcctcgggt gtcacatatt
      121 aggtgctcaa taaatgtgga cataggaaac gaaaagtccg aatctgtcct tacgccccca
      181 agcgaattct ggggcgcgcg ggtttattcc gacccactac cacatcgcgt ttcctgaggt
      241 aacccggcct cggctctgcg gccccagcgg ctggagagcc acggagaagg cgggctacgg
      301 gcgacaagat ggagagccgg cccgagaggg acagaggccg cgctggcagc gagctggggg
      361 gcccacctga ccgtcctgcg ggcagcccgg ccccgcgctc ccattgacaa ggaggtccgc
      421 cgccggcgcg tggggcggga gcggaggcgg ggtgggcgcc ccggcgcgcg cccggcccca
      481 ctccccgccc ccgccagtcc cgcaagcacc caccccgggg gagccgcggg ccgggagggc
      541 gctgggggga ggggcaggcc tccgcgacgc gtgtgcgcgg cggcggccgg tgacgcgaac
      601 tgcggcgcgc gcctcccccg ccccgcgccc tccgtcccgg gggcccggcg cgcggccctg
      661 ctgacgtcag ctggcggccc gcggagccgg gtgcgcagag ccgtggcgca gcgtcgcgcg
      721 tgcgctggcc tcctccccgc cccgggccca ggcgcgcgcg cgcttgttcg ctctcccatt
      781 ttttttttcc cctccctccc tgcctctctc tctctccctc tccctcgagc tcccggctgg
      841 ctgcggctcc ctggcgctct ccctctctct ccggtaggct caccgagcga tgcgagctct
      901 gggagacagc gacgccgcct cccgctagag acctgcccct cggcccggcc ccctgcccaa
      961 ccctgcccag cgcgcggggg tcggcgaagg cgccgcggac gcaccgacgg ctgaagagcg
     1021 gcgatgcaca tgcactagca gcacccccta actcactccc tccacatccc gcgccgccgc
     1081 cgccgcctcc tccacctcct cctccgccgc cgccgcctcc tcctcctccg gcagccgcgg
     1141 cagcaggacc caccctgccc cccaccccac cctctgtcgg ctccggctgc ggctccagcc
     1201 tcgactatta ttttatttat tttgggtcgt gcacaagcct cagtgcctgc agtccgcgcc
     1261 tcctcggccc gcgggcgcct cctcccttgg ctccggagcc ccagaccccg gccaccctcg
     1321 attcgacaac cccagacccc tgccagctgc cgcgagtctc cgctgctgga atcttgttag
     1381 cggctgtctt tttggagggt tctggtttcc cgacattttt gtttccagcc caggagagga
     1441 tatcgtgatt ttcccccctt gagccagccc aggctctgct ctctgggggg gtggggggcg
     1501 ctccaagccg gggagccgtg ccagccgagt cgtgcgggct gtggcaggga aggggccacc
     1561 atgggatgta ctctgagcgc agaggagaga gccgccctcg agcggagcaa ggcgattgag
     1621 aaaaacctca aagaggatgg catcagcgcc gccaaagacg tgaaattact cctgctcggt
     1681 aaggaccgcc gctgctaccc ccatcccccg accccggcca ctccgcaccc cctgccacca
     1741 gctcccccac cccactcgcg cccgggagac ctggtcccca agttggcacc accatgtgcc
     1801 caggatcgcc caccccctcg catgccttag tccccccctc cccctgttcc cttaagctga
     1861 cactcaccag tttttcccca ctgtctgtgt cccaacaggg gctggagaat caggaaaaag
     1921 caccattgtg aagcagatga agtaagtccc tgtggcattg ggattcgtac ttttat
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ02     185 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 3.
ACCESSION   M60157
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     2 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 185)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..163
                     /number=3
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       47 a     44 c     51 g     43 t
ORIGIN
        1 gtgtgtgtgg tttttctcta ggatcatcca tgaagatggc ttctccggag aagacgtgaa
       61 acagtacaag cctgttgtct acagcaacac tatccagtcc ctggcagcca tcgtccgggc
      121 catggacact ttgggcatcg aatatggtga taaggagaga aaggtaggcc cctgagccca
      181 taagc
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ03     299 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 4.
ACCESSION   M60158
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     3 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..180
                     /number=4
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       63 a     78 c     97 g     61 t
ORIGIN
        1 catccacctc tcctcacagg ctgacgccaa gatggtgtgt gatgtggtga gtcggatgga
       61 agacaccgag cccttctctg cagagctgct ttctgccatg atgcggctct ggggcgactc
      121 aggaatccaa gagtgcttca accggtcccg ggagtatcaa ctcaacgact ctgccaaata
      181 gtgagtgtcc cagcggcgca tggcctggag ccgggcagtg atgcgggagt ggaagggact
      241 gtgatgggat ggcagagcaa ggaggattct cgctgagtca cgctccggag attctccat
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ04     189 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 5.
ACCESSION   M60159
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     4 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 189)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..150
                     /number=5
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       44 a     65 c     48 g     32 t
ORIGIN
        1 cctgtttgtt gccatcctca gctacctgga cagcctggat cggattgggg ccgccgacta
       61 ccagcccact gagcaggaca tcctccgaac cagggtcaaa accactggca tcgtagaaac
      121 ccacttcaca ttcaagaacc tccacttcag gtgaggccca gagaggcccc caggccctgg
      181 cgagggcta
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ05     189 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 6.
ACCESSION   M60160
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     5 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 189)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            22..151
                     /number=6
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       35 a     59 c     60 g     35 t
ORIGIN
        1 ccagctccct gcctcctaca ggctgtttga cgtcggaggc cagcgatctg aacgcaagaa
       61 gtggatccat tgcttcgagg acgtcacggc catcattttc tgtgtcgcgc tcagcggcta
      121 tgaccaggtg ctccacgaag acgaaaccac ggtgagtggc ctgggccccc cgggcagggg
      181 gcagcgctg
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ06     184 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 7B.
ACCESSION   M60161
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     6 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 184)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..173
                     /number=7B
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       55 a     54 c     32 g     43 t
ORIGIN
        1 cccctccact ctgttgcaga accgcatgca cgaatccctg aagctttttg acagcatctg
       61 caacaacaaa tggttcacag acacgtccat catcctgttt cttaacaaga aggacatatt
      121 tgaagagaag atcaagaagt ccccgctcac catctgcttt cctgaatata caggtagaga
      181 cccc
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ07     291 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 8B.
ACCESSION   M60162
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     7 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            21..>208
                     /number=8B
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       61 a    112 c     66 g     52 t
ORIGIN
        1 tgccttgttt tgctctgcag gccccagcgc cttcacagaa gccgtggctt acatccaggc
       61 ccagtacgag agcaagaaca agtcagccca caaagagatc tacagccacg tcacctgcgc
      121 cacggacacc aacaacatcc agtttgtctt tgatgctgtg acggacgtca tcatcgccaa
      181 aaacctgcgg ggctgtggac tctactgagc ccagccgccc tgcccggcac ccttgccctg
      241 cctggcctgc cgcccccccc tccccctgga accaagctcc accagtctca g
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ08     183 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 7A.
ACCESSION   M60163
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     8 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 183)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            20..173
                     /number=7A
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       45 a     57 c     32 g     49 t
ORIGIN
        1 tcccttcctg cggccgcaga accgcatgca cgagtctctc atgctcttcg actccatctg
       61 taacaacaag ttcttcatcg atacctccat cattctcttc ctcaacaaga aagatctctt
      121 tggcgagaag atcaagaagt cacctttgac catctgcttt cctgaataca caggtgggtg
      181 cca
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ09     289 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 8A.
ACCESSION   M60164
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     9 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     exon            21..237
                     /number=8A
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT       81 a     88 c     55 g     65 t
ORIGIN
        1 tcttctgtgt cttgttacag gccccaatac ctatgaagac gcagccgcct acatccaagc
       61 acaatttgaa agcaaaaacc gctcacccaa caaagaaata tattgtcaca tgacttgtgc
      121 cacagacacg aataacatcc aggtggtgtt cgacgccgtc accgacatca tcattgccaa
      181 caacctccgg ggctgcggct tgtactgacc tcttgtcctg tatagcaacc tattttggta
      241 atgattccag cacccacaga acagcttgcg tgcgcgcgca tacacacac
//

GenBank-Updates@genbank.bio.net (03/27/91)

LOCUS       HUMGOAQ10    1439 bp ds-DNA             PRI       27-MAR-1991
DEFINITION  Human guanine nucleotide-binding regulatory protein (Go-alpha)
            gene, exon 9.
ACCESSION   M60165
KEYWORDS    alternative splicing; go-alpha;
            guanine nucleotide-binding regulatory protein.
SEGMENT     10 of 10
SOURCE      Human DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Tsukamoto,T., Toyama,R., Matsuoka,M., Kozasa,T., Itoh,H. and
            Kaziro,Y.
  TITLE     Structure of human Go(alpha) gene and two rat Go(alpha) cDNAs: Two
            different Go(alpha) mRNAs are generated by alternative splicing
  JOURNAL   Unpublished (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     mRNA            join(M60156:<1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60163:20..173,M60164:21..237,46..>1166)
                     /product="guanine nucleotide-binding regulatory protein 1"
                     /gene="Go-alpha"
                     /partial
     mRNA            join(M60156:<1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60161:20..173,M60162:21..>208)
                     /product="guanine nucleotide-binding regulatory protein 2"
                     /gene="Go-alpha"
                     /partial
     CDS             join(M60156:1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60163:20..173,M60164:21..208)
                     /product="guanine nucleotide-binding regulatory protein 1"
                     /gene="Go-alpha"
                     /codon_start=1561
     CDS             join(M60156:1561..1678,M60156:1899..1941,M60157:22..163,
                     M60158:20..180,M60159:22..150,M60160:22..151,
                     M60161:20..173,M60162:21..208)
                     /product="guanine nucleotide-binding regulatory protein 2"
                     /gene="Go-alpha"
                     /codon_start=1561
     exon            46..>1166
                     /number=9
                     /product="guanine nucleotide-binding regulatory protein"
                     /gene="Go-alpha"
BASE COUNT      385 a    376 c    289 g    389 t
ORIGIN
        1 tcacagaaaa tggtcagact ggacccctta tctctctctc tacagactgc ttcacggact
       61 ctttgctgtt gacgttgatc tcctggtagc atgacctttt ggcctttgta agacacacag
      121 cctttctgta tcaagcccct gtctaaccta cgaccccaga gtgactgacg gctgtgtatt
      181 tctgtagaat gctgtagaat ccggttttag ttgagtcttc acatttagaa tttgaaagga
      241 aaaacagaac atttctcatg tgctttgtag cttaaaaaaa ggaaaactca ccatttcaac
      301 catatttctt tttcttgcaa aacaaacata cccatctgca ccgacgcctg ccccgtccca
      361 cctcgcgcga gcccctggag ctcctgctgg gggaggccca tctgccgcct ggggctccgg
      421 tgcggtgcat ggtccgagga gtgtgctcag gccgggcttt ccagaaggca caggccactg
      481 caaaccctgc tgctgccggc cgcccagaca ccacagacgc cactggcggc cctaagccac
      541 tcccgccaca cgctcactcc aggttcgtat agaaaaagca cagctctcac tggccagtag
      601 ctgccaaaaa gaacacccat cgtataagga aatccagccc catagaaaac aatctgccca
      661 ccgaccccct ttctaaggat agcctttgta ggggtttttt ggttcctttt tttttttttc
      721 agtttgtgtt tttacttttg tcccgccgag tactatgtat taccagcccc cacccacaga
      781 tcagtttcct agtctttggg aaacgggttg tgtttttttt cctttgccgt gttggatttc
      841 cggtcgcggc tgacacctcc cttcgtgtgt gcgcccctcc ccacccctgc ctgtgttctg
      901 tgccctgtgt ccgctctctc atgtggggat gtttgtgctg cagacaaaaa gaacaaaaaa
      961 aaatttttaa ataccacaag atggaaaaaa aaaacaaaaa aatttaaaaa gatggaatgt
     1021 agtgtttaca ttaaagccgc cgttttcatg accaatccta tgtcatttct actttgacta
     1081 atacccaaac cctaaacctc ttcacggttt cacttttaag acttaatctg tgctgaagaa
     1141 gaccagtcac agccatttca aataaagagg aggcaaaaag acaaaacaca caaaaaatta
     1201 aaaaaaaaaa cttaaaaaaa aaaggaaaaa agaaaaaaaa gcccacgggt ctttgtaagc
     1261 ctttctattc ccaatcggtg aggtttctgt gatatcttac acactgccag tctacttctc
     1321 tgactaatgg aaaattcctg tgtagctcaa taaaagagaa tgtttgtctg tactcctgag
     1381 tctcaccctg tgccttccaa cgatggttat ttggggtggg cttcattctg gcaggagag
//